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All Journal Jurnal Pembelajaran dan Biologi Nukleus Journal of Community Empowerment for Health Indonesian Journal of Health Research and Development Bencoolen Journal of Pharmacy
Masrijal, Camelia Dwi Putri
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Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Education Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Medicine & Pharmacology Nursing Public Health

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FORMULASI, EVALUASI DAN UJI STABILITAS FISIK SEDIAAN GEL ANTIOKSIDAN EKSTRAK TALI PUTRI (Cassytha filiformis L) Setiawan, Roby; Masrijal, Camelia Dwi Putri; Hermansyah, Oky; Rahmawati, Suci; Sari, Rose Intan Perma; Cahyani, Arinda Nur
BENCOOLEN JOURNAL OF PHARMACY Vol. 3 No. 1 (2023): April
Publisher : UNIB PRESS

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33369/bjp.v3i1.27649

Abstract

Tali putri (Cassytha filiformis L) termasuk ke dalam famili lauraceae, yang memiliki aktivitas antioksidan alami. Tanaman ini banyak dijumpai di kawasan pesisir Pantai Panjang Kota Bengkulu. Tujuan penelitiaan ini adalah mendapatkan formula gel antioksidan ekstrak Tali Putri (Cassytha filiformis L) terbaik berdasarkan evaluasi dan uji stabilitasnya. Tumbuahan Tali Putri (Cassytha filiformis L) diekstrak dengan metode maserasi selama 3x24 jam menggunakan pelarut metanol. Penelitian ini menggunakan ekstrak tali putri (Cassytha filiformis L) sebanyak 3%, yang diformulasikan ke dalam 3 formula dengan variasi basis HPMC, yaitu 7% (F1), 10% (F2), dan 15% (F3). Uji evaluasi yang dilakukan yaitu uji homogenitas, uji organoleptis, uji pH, dan uji viskositas. Uji stabilitas fisik menggunakan metode cycling test dilakukan selama 3 hari. Hasil pengujian randemen ekstrak yang diperoleh adalah 2,812%. Uji pH menunjukan gel memiliki pH 6,4 (F1), 6,3 (F2), dan 6,2 (F3). Uji viskositas menunjukan gel memiliki viskositas 2530 cps (F1), 1610 cps (F2), 1920 cps (F3). Uji stabilitas metode cycling test terjadi sineresis di setiap formulasi dengan waktu terlama pada F1. Gel mengandung ekstrak tali putri (Cassytha filiformis L) yang terbaik berdasarkan hasil evaluasi dan uji stabilitas adalah formula 1 (F1).
Formulasi Blush On Stick dengan Zat Pewarna Alami Ekstrak Buah Murbei (Morus alba L) dengan Variasi Lilin Carnauba Sebagai Basis: Formulasi Blush On Stick dengan Zat Pewarna Alami Ekstrak Buah Murbei (Morus alba L) dengan Variasi Lilin Carnauba Sebagai Basis Patmawati, Aprisa Riski; Rose, Rose Intan Perma Sari; Hermansyah, Oky; Masrijal, Camelia Dwi Putri; Salamet, Samwilson
BENCOOLEN JOURNAL OF PHARMACY Vol. 4 No. 2 (2024): Oktober
Publisher : UNIB PRESS

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33369/bjp.v4i2.36748

Abstract

: Blush on stick adalah sediaan kosmetik yang digunakan untuk mewarnai pipi dengan sentuhan artistik sehingga dapat meningkatkan estetika dalam tata rias wajah. Salah satu bahan alam yang dapat dijadikan pewarna adalah buah murbei (Morus alba L.) karena mengandung antosianin yang tinggih. Tujuan penelitian ini untuk mengetahui apakah ekstrak buah murbei dapat dijadikan sebagai pewarna pada sediaan blush on bentuk stick dengan memvariasikan lilin carnauba sebagai basis dan mengevaluasi sediaan blush on. Formulasi sediaan blush on yang dibuat yaitu menggunakan zat warna dari ekstrak buah murbei dengan konsentrasi 10% dan konsentrasi lilin carnauba pada masing-masing formula adalah 10%, 20% dan 30%. Pengujian yang dilakukan antara lain pemeriksaan organoleptis, uji homogenitas, uji pH, uji poles, uji keretakan, uji hedonik dan uji iritasi. Seluruh formula yang dibuat telah memenuhi persyaratan uji pH, uji poles, dan uji keretaka, sedangkan pada uji homogenitas terdapat sedikit butiran pada masing-masing sediaan. Pemeriksaan organoleptis menunjukkan bau keseluruhan sediaan blush on adalah bau khas oleum rosae dan bentuk keseluruhan sediaan blush on berbentuk batang padat (stick) dengan warna merah tua. Hasil uji iritasi menunjukkan bahwa seluruh sediaan tidak menunjukkan adanya reaksi iritasi. Hasil uji kesukaan menunjukkan bahwa F2 (20%) yang paling disukai oleh panelis. Kata Kunci: Ckstrak Buah Murbei; Blush On; Pewarna Alami, Stick
Formulation and Test of Burns Healing Effects of Preparations Cream Extract Leaf Nangka Kuning (Vincetoxicum villosum (Blume) Kuntze) Oktoviani, Oktoviani; Masrijal, Camelia Dwi Putri; Slamet, Samwilson; Wirahmi, Nori; Versita, Riana; Sari, Rose Intan Perma
Indonesian Journal of Health Research and Development Vol. 2 No. 1 (2024): Indonesian Journal of Health Research and Development (February)
Publisher : CV Media Inti Teknologi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58723/ijhrd.v2i1.159

Abstract

V. villosum (Blume) Kuntze shows inhibition of the growth of Pseudomonas aeruginosa which is usually the cause of infection in burn wounds. The aim of this research was to formulate V. villosum (Blume) Kuntze leaf extract into a cream preparation and determine the time needed for V. villosum (Blume) Kuntze leaf extract cream to heal burn wounds in rabbits. This research was a type of experimental research. The research was conducted at the University of Bengkulu Laboratory in September 2022-August 2023. The equipment used was the Ohaus Starter 3100 brand pH meter and the NDJ-8S viscometer. The materials used are V. villosum (Blume) Kuntze leaf extract, mice, ethanol solvent. Oil-in-water (O/W) phase cream formulation with 3 variations of stearic acid and triethonolamine emulsifiers (15:4), (16:3) and (17:2). Then the three formulas were evaluated for their preparations which included organoleptic tests, homogeneity tests, pH tests, adhesion tests, spreadability tests, viscosity tests and descriptive stability tests. The activity test against burn wound infections used rabbits consisting of groups K1 (without treatment), K2 (given 0.2% hyaluronic acid cream), P1 (given 2% V. villosum (Blume) Kuntze leaf extract), and P2 (given 2% V. villosum (Blume) Kuntze leaf extract cream). Groups K2, P1 and P2 showed perfect wound healing on day 12. Meanwhile group K1 experienced incomplete wound healing until day 14. Based on the results of the study it can be concluded that the cream formulations I, II and III were declared stable at a temperature of 25º and the extract cream Kuntze V. villosum (Blume) Kuntze leaves showed complete wound healing in 12 days. The results of the Kruskal Wallis test obtained p value = 0.670 > 0.05, which means there is no difference in the length of the healing process for all treatments.
Antibacterial Activity of Ethanol Extracts from Leaves and Flowers of Katang-Katang Ipomoea pes-caprae (L) R.Br Against Pseudomonas aeruginosa Wibowo, Risky Hadi; Nabella, Inastia; Fitri, Sabrina; Rahmawati, Suci; Hermansyah, Oky; Masrijal, Camelia Dwi Putri; Slamet, Samwilson; Mashudi, Mashudi; Hidayah, Thoriqul
JURNAL PEMBELAJARAN DAN BIOLOGI NUKLEUS Vol 10, No 1: Jurnal Pembelajaran Dan Biologi Nukleus March 2024
Publisher : Universitas Labuhanbatu

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36987/jpbn.v10i1.4779

Abstract

The resistance character and infection pathogenicity of bacteria to humans is currently increasing, so there is a need for new alternative drugs. The bioactive compounds contained in katang-katang plant are one of the new sources of antibacterials obtained from nature. This study used leaves and flower samples of Katang-katang (Ipomoea pes-caprae (L)R.Br) obtained from the coastal area of Bengkulu City. The purpose of this study was to determine the phytochemical compounds of the leaves and flower extracts of Katang-katang using color reaction test method and to determine the antibacterial activity of the extracts of the leaves and flowers of Katang-katang against the testing pathogenic bacteria (Pseudomonas aeruginosa) at concentrations of 10%,25%,50%,75% using disc diffusion method. The leaves and flowers ethanolic extracts of the Katang - katang were proven contain secondary metabolites such as alkaloids, flavanoids, saponins, tannins and steroids. Antibacterial effectiveness of the ethanol extract from leaves was classified as moderate at a concentration of 50% with a measured inhibition zone of  6.30 mm and a concentration of 75% with an inhibition zone size 8.13 mm. In contrast, effectiveness of the antibacterial extracted from flower was classified as weak at a concentration of 50% with an inhibition zone 4.50mm and moderate at a concentration of 75% with a measured inhibition zone size of 6.40 mm. The experiment revealed that the leaves and flowers of the Katang-katang have antibacterial potential against P. aeruginosa which could be developed as a medicinal ingredient in the future
Nurturing Natural Beauty: Empowering MAN 1 Model Bengkulu's Female Students with Red Dragon Fruit (Hylocereus polyrhizus) Cosmetics Crafting Workshop Masrijal, Camelia Dwi Putri; Taurina, Hilda; Lubis, Ashar Muda; Permasari, Rose Intan; Hermansyah, Oky; Slamet, Samwilson; Rahmawati, Suci; Rahmadhani, Aliyah; Monalisa, Shelyn Puteri; Wahid, Muhammad Ali Ashar
Journal of Community Empowerment for Health Vol 7, No 1 (2024)
Publisher : Faculty of Medicine, Public Health, and Nursing, Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/jcoemph.90334

Abstract

Introduction: The use of lipstick, blush-on, and various colored cosmetic products is highly popular among teenage girls. However, the adverse effects of hazardous colorants in cosmetics include respiratory irritations, skin irritations, eye injuries, gastrointestinal toxicity, and carcinogenic properties. Red Dragon Fruit contains a significant amount of red anthocyanin antioxidants, making it a viable natural colorant for food, cosmetics, and textiles. This community engagement project aimed to enhance the understanding of teenage girls, especially students of MAN 1 Model City of Bengkulu, regarding illegal cosmetics containing harmful and prohibited ingredients. It also aimed to improve the girls' skills in crafting natural Lip Tint and Blush-On preparations from Red Dragon Fruit (Hylocereus Polyrhizus), promoting a return to nature in cosmetic choices. This initiative was expected to inspire creative ideas among teenagers for designing alternative economic activities centered on producing natural and halal cosmetics made from herbal ingredients. Methods: The project involved educational and awareness-raising activities about the dangers of forbidden cosmetic ingredients, followed by workshops on making Lip Tint and Blush-On formulations. These workshops were led by faculty members from the School of Medicine and the School of Pharmacy, with assistance from students of the Faculty of Mathematics and Natural Sciences at the University of Bengkulu. Results: Evaluation results showed that workshop participants experienced a 63.2% increased in knowledge and gained the ability to independently create Lip Tint and Blush-On products from red dragon fruit. Conclusion: The workshop successfully produced natural Lip Tint and Blush On and the project also heightened the students' interest in the Pharmacy Program.
Co-Authors : Samwilson Slamet, : Samwilson Arinda Nur Cahyani Ashar Muda Lubis Fitri, Sabrina Hidayah, Thoriqul Mashudi Mashudi Monalisa, Shelyn Puteri Nabella, Inastia Oktoviani, Oktoviani Oky Hermansyah Patmawati, Aprisa Riski Permasari, Rose Intan Rahmadhani, Aliyah ROBY SETIAWAN Rose, Rose Intan Perma Sari Salamet, Samwilson Sari, Rose Intan Perma Suci Rahmawati Suci Rahmawati, Suci Taurina, Hilda Versita, Riana Wahid, Muhammad Ali Ashar Wibowo, Risky Hadi Wirahmi, Nori