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Sarosa, Pandit
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Medicine & Pharmacology

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Perbandingan Daya Guna Profilaksis Pethidine 0,5 Mg/KgBB, Tramadol 1 Mg/KgBB dan Ketamin 1 Mg/KgBB untuk Mencegah Shivering Pasca Operasi Laparaskopi dengan Anestesi Umum Iqbal, Muhammad; Sarosa, Pandit; Sari, Djayanti
Jurnal Komplikasi Anestesi Vol 5 No 1 (2017): Volume 5 Number 1 (2018)
Publisher : This journal is published by the Department of Anesthesiology and Intensive Therapy of Faculty of Medicine, Public Health and Nursing, in collaboration with the Indonesian Society of Anesthesiology and Intensive Therapy , Yogyakarta Special Region Br

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/jka.v5i1.7316

Abstract

Background: Post anaesthesia shivering is a autonom mechanism compensation against fall body temperature to increased heat body production. Hypothermia during operation is primary cause post anaesthetic shivering. Shivering can increased cardiac activity, intraocular pressure, intracranial pressure and create postoperative discomfort condition. Objective: The aim of this study is compare effectivity of pethidin 0,5 mg/kg, tramadol 1 mg/kg and ketamin 0,5 mg/kg as a prophylactic drug of shivering after laparascopy surgery with general anesthesia. Methods: This study is double blind randomized controlled trial. The subject were 193 patient, male or female with age 18-60, physical status of ASA I and II, who undergo of laparascopy surgery with general anesthesia. Subject were divided into three group. Group P with pethidin 0,5 mg/kg, group T with tramadol 1 mg/kg, group K with ketamin 0,5 mg/kg, drug were diluted with 10 mL normal saline. Prophylactic drugs given when superficial skin closure. Results: Is done measurement systolic blood pressure, diastolic blood pressure, heart rate and body temperature. Measurement done before procedure anaesthesia, during anesthesia and at the recovery room. Conclusion : Shivering assessment began after terminating inhalation anaesthesia agen.
Efek Pemberian Ketamin Dosis 0,5 Mg/Kgbb Terhadap Onset Blokade Neuromuskular Oleh Atrakurium Al-Hilal, Said Rival; Sarosa H, Pandit; Widodo, Untung
Jurnal Komplikasi Anestesi Vol 5 No 2 (2018): Volume 5 Number 2 (2018)
Publisher : This journal is published by the Department of Anesthesiology and Intensive Therapy of Faculty of Medicine, Public Health and Nursing, in collaboration with the Indonesian Society of Anesthesiology and Intensive Therapy , Yogyakarta Special Region Br

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/jka.v5i2.7332

Abstract

Background. Atracurium is a nondepolarizing muscle relaxant agent. The onset of this drug is slower than succinylcholine thus limiting its use. Various attempts had been made to accelerate the onset of the nondepolarizing muscle relaxants. Various reports suggest that ketamine is associated with a better intubation conditions. Aims. The aim of this study was to determine the effect of ketamine 0.5 mg.kg-1 on neuromuscular blockade onset of atracurium. Method. The method was a Randomized Controlled Trial (RCT) with double blinding. Eighty adult patients aged 18-65 years with physical status according to class I and II of ASA classification who were undergoing elective surgery under general anesthesia in November 2016 up to January 2017, patients who met the inclusion and exclusion criteria were randomly divided into two groups: K (Ketamine ) and group S (Saline Control). Group K was given ketamine 0.5 mg.kg-1 while the S was given Saline. Eight patients were otherwise drop out because of tool’s error. The Onset of atracurium was measured by using a Train of Four. Result. The results of this study were the onset of neuromuscular blockade by atracurium in the ketamine group significantly faster (160.500 ± 58.956 seconds vs 288.750 ± 135.038 seconds; p = 0.001). Hemodynamic 8 changes (∆MAP : 6,500±7,965 mmHg vs 10,750±14,655 mmHg & ∆pulse rate : 3,737±11,700 x/minute vs 4,333±12,254 x/min) was not statistically significant (p = 0.123 and p = 0.831). Conclusion: The administration of ketamine 0.5 mgkg-1 accelerate the onset of neuromuscular blockade of atracurium.
Tablet Gabapentin sebagai Analgesia Multimodal Perioperatif dalam Anestesi Umum Widodo, Untung; Sarosa, Pandit; Gentong, Metia Gledis Gilang
Jurnal Komplikasi Anestesi Vol 6 No 2 (2019): Volume 6 Number 2 (2019)
Publisher : This journal is published by the Department of Anesthesiology and Intensive Therapy of Faculty of Medicine, Public Health and Nursing, in collaboration with the Indonesian Society of Anesthesiology and Intensive Therapy , Yogyakarta Special Region Br

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/jka.v6i2.7355

Abstract

Multimodal analgesia is a combination of different drugs with different actions and targets in the nervoussystem, producing addictive effects or synergistic analgesia by reducing the side effects of single drug. The response of the humoral and neuronal complexes that occur due to surgery requires balanced perioperative pain management. Multimodal use can reduce the dose of each drug and reduce the incidence of side effects of drugs used for the treatment of perioperative pain, which can shorten hospitalization time, speed-up recovery and function of the body, and reduce health costs. Today, the American Society of Anesthesiologists Task Force on Acute Pain Management advocates the use of multimodal analgesia.
Co-Authors Akhmad Yun Jufan Al-Hilal, Said Rival Bambang S, Bambang Bambang Suryono, Bambang Djayanti Sari Fauzani N, Achmad Gentong, Metia Gledis Gilang Hamdany, Ferry Hartono, Dedy Krisdiyantoro, Nova Marthysal, Audhiaz Mochammad Imron Awalludin Nur, Rifdhani Fakhrudin Pangroso, Agung Pangroso Pratama, Andhika Marthsyal Saputra, Rory Denny Setiawan, Yosy Budi Sudadi Untung Widodo, Untung Yudo P, Bhirowo Yunita Widyastuti