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All Journal Microbiology Indonesia Jurnal Farmasi Sains dan Komunitas Jurnal Kesehatan Medika Saintika Jurnal Penelitian Farmasi Indonesia SELAPARANG: Jurnal Pengabdian Masyarakat Berkemajuan JURNAL PENDIDIKAN TAMBUSAI JFL : Jurnal Farmasi Lampung Abdi: Jurnal Pengabdian dan Pemberdayaan Masyarakat Jurnal Pengabdian UNDIKMA JAFP (Jurnal Akademi Farmasi Prayoga) Jurnal Tata Rias (JTR) Florona : Jurnal Ilmiah Kesehatan Jurnal Katalisator Jurnal Tata Rias (JTR) JBC

Ringga Novelni

Prodi Pendidikan Tata Rias Dan Kecantikan, Fakultas Pariwisata Dan Perhotelan, Universitas Negeri Padang

Author-ID : 7783039

Religion Agriculture, Biological Sciences & Forestry Arts Humanities Biochemistry, Genetics & Molecular Biology Chemistry Computer Science & IT Control & Systems Engineering Decision Sciences, Operations Research & Management Economics, Econometrics & Finance Education Engineering Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Library & Information Science Mathematics Medicine & Pharmacology Nursing Public Health Social Sciences Veterinary Other

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UJI AKTIVITAS ANTIDEPRESAN EKSTRAK ETANOL DAUN GEDI HIJAU (Abelmoschus manihot (L.) Medik) PADA MENCIT PUTIH JANTAN (Mus mussculus) Ringga Novelni; Mimi Aria; Prima Minerva; Amelia Utami Putri
JURNAL KATALISATOR Vol. 7 No. 1 (2022): Jurnal Katalisator Volume 7 Nomor 1, April 2022
Publisher : LLDIKTI X Sumbar, Riau, Jambi, Kepri

Tumbuhan gedi hijau (Abelmoschus manihot (L.) merupakan salah satu alternatif yang bisa digunakan untuk pengobatan depresi. Tanaman ini mengandung senyawa-senyawa yang memiliki efek sebagai antidepresan, seperti quercetin, isoquercitrin, hyperoside, hibifolin, quercetin- 3'-0-glukosida, dan isorhamnetin. Tujuan penelitian ini adalah untuk mengetahui aktivitas antidepresan ekstrak etanol daun gedi hijau (Abelmoschus manihot (L.) Medik). Sebelum penelitian dilakukan, semua hewan uji dibuat menjadi stress dengan metode Tail suspension test selama 10 hari. Pemberian sediaan uji dilakukan hari ke-11 secara peroral, setelah 1 jam pemberian sediaan uji baru diamati aktivitas antidepresan dengan uji immobility time pada mencit dengan menggunakan stopwatch selama 5 menit. Kemudian diperoleh hasil berdasarkan urutan kelompok (kontrol negatif, kontrol pembanding, serta kelompok dosis 150; 250 dan 350 mg/Kg BB) dengan durasi immobility time (284,75 detik ; 159,5 detik ; 222,75 detik ; 178,5 detik ; 131,75 detik). Hasil penelitian ini dianalisis dengan anova satu arah dengan nilai signifikansinya (p<0,05). Hasil analisa statistik menunujukkan bahwa ekstrak etanol daun gedi hijau memiliki aktivitas sebagai antidepresan dan pemberian variasi dosis ekstrak etanol daun gedi hijau (Abelmoschus manihot (L.) Medik) memberikan pengaruh terhadap mencit putih jantan (Mus mussculus) dengan hasil dosis yang lebih efektif sebagai antidepresan adalah dosis 250 mg/KgBB.

EFEKTIVITAS ANTIDIABETES EKSTRAK DAUN KAYU MANIS (Cinnamomum burmanni) PADA MENCIT PUTIH JANTAN Diza Sartika; Miftahur Rahmi; Ringga Novelni; Fatma Adilla
JURNAL KATALISATOR Vol. 8 No. 1 (2023): Jurnal Katalisator Volume 8 No. 1, April 2023
Publisher : LLDIKTI X Sumbar, Riau, Jambi, Kepri

Cinnamon leaf extract (Cinnamomum burmanni) contains flavonoid compounds that function to stimulate insulin activation so that it can be used for anti-hyperglycemia.The purpose of this study was to determine the effect of giving cinnamon leaf extract (Cinnamomum burmanni) to male white mice induced by dexamethasone and 10% glucose and to determine the effective dose of cinnamon leaf extract (Cinnamomum burmanni) which can reduce blood glucose levels in mice. hyperglycemia. The group was divided into 6 groups, consisting of negative control, positive control, dose variation of 250mg/kg bw, 500mg/kg bw and 750mg/kg bw and the comparison group was Glibenclamide. The inducer used was dexamethasone 5mg/ml and 10% glucose. Induction of dexametason is carried out for 6 days and continued the administration of 10% glucose for 2 days, then given test preparations from days 7, 14 and 21 after the induction of dexamethasone and glucose 10%. The results showed that the best dose in reducing blood sugar levels in mice was a dose of 750 mg/KgBW with a percentage reduction of 26.33%. Two-way ANOVA statistical analysis test on the percentage of significant antidiabetic (p<0.05). The conclusion of this study is that the ethanolic extract of cinnamon leaves has the effect of activity in lowering blood glucose levels on the 21st day.

FORMULATION AND ANTIBACTERIAL ACTIVITY TEST OF ANTI-ACNE GEL FROM ETHANOL EXTRACT OF SENDUDUK LEAVES (Melastoma malabathricum. L) Novelni, Ringga; Mimi Yupelimi; Dina Agustina; Diza Sartika; Vici Syahril Chairani
JURNAL KATALISATOR Vol. 9 No. 1 (2024): Jurnal Katalisator Volume 9 No.1, April 2024
Publisher : LLDIKTI X Sumbar, Riau, Jambi, Kepri

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62769/katalisator.v9i1.2902

Treatment of inflamed acne is done by administering antibiotics and chemicals, which can usually cause side effects such as skin irritation and resistance. To avoid this, it can be replaced by doing traditional treatment using natural ingredients. Senduduk plant (Melastoma malabathricum L.) is one of the natural ingredients that can be used to treat acne because it contains secondary metabolites of flavonoids, phenolics, tannins and terpenoids that are very potential as antibacterials. This study aims to determine the ethanol extract of senduduk leaves can be formulated in a physically stable gel dosage form and determine the antibacterial activity against Propionibacterium acne and Staphylococcus aureus bacteria. This study used an experimental method by making 3 types of formulas containing ethanol extract of senduduk leaves (Melastoma malabathricum L.) 1.5%, 2.5% and 3.5%. Furthermore, the evaluation of the gel preparation included organoleptic test, homogeneity test, pH test, spreadability test and adhesion test. Antibacterial activity testing was carried out by the pitting diffusion method using Klindamycin as a positive control. Based on the results of the gel preparation evaluation, it shows that the anti-acne gel preparation has physical quality that meets the standards. Antibacterial activity test of senduduk leaf ethanol extract gel against S.aureus bacteria at concentrations of 1.5%, 2.5% and 3.5% had inhibition zone diameters of 20.3 mm, 21.4 mm, and 24.2 mm, respectively, while against P. acnes bacteria it was 21.6 mm, 25.3 mm, and 26.5 mm. It can be concluded that the anti-acne gel of senduduk leaf ethanol extract has antibacterial activity against S. aureus and P. acnes bacteria and can be made into an anti-acne gel dosage form.

Co-Authors Alamsyah Hanafiah Alena, Meysa Amelia Utami Putri Anisa, Ramatika Azyenela, Lola Dewi, Siska Miga Dina Agustina Diza Sartika Dovi Septiari Fadhillah Subegti, Dinda Fatma Adilla Fira Andila Gina Amelia Govaldi Govaldi, Gina Amelia Ifmaily, Ifmaily Irma Yulinda Irwandi Irwandi Latisa, Putri Lola Azyenela Marlina Marlina Maulani Meutia Melati, Pegi Melzy Putri Sani Mentari, Tyas Asih Surya Miftahur Rahmi Mimi Aria Mimi Yupelimi Nessa Nessa Oktarina, Rahmi Prima Minerva Rahma Putri, Dian RAVEINAL RAVEINAL Ria Afrianti Rifanda, Firara Safitri, Mayang Sakti, Lara Sartika, Diza Sri Selva, Wilvy Tisa Mandala Sari Vici Syahril Chairani Viora Lusiana Satri Yanita, Merita Zatil Hidayah, Adilah

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