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All Journal Jurnal Biologi Universitas Andalas JOPS (Journal Of Pharmacy and Science) Jurnal Pijar MIPA Jurnal Pengabdian Masyarakat Bidang Sains dan Teknologi SITAWA : Jurnal Farmasi Sains dan Obat Tradisional
arif ferdian
Universitas Baiturrahmah
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Studi Etnobotani Pemanfaatan Tumbuhan Obat Tradisional oleh Masyarakat Nagari Sijunjung Meiridha Mutiara Andania; Relin Yesika; arif ferdian
Jurnal Biologi Universitas Andalas Vol 12, No 1 (2024)
Publisher : Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jbioua.12.1.01-04.2024

Abstract

Minangkabau is one of the ethnics that uses plants as medicine. In this ethnobotanical study, the aim was to find out the use of plants as medicine by the people of Sijunjung. Data collection was carried out directly by interviewing native people. From the result known that there are about 42 types of plants used by the indigenous people of Sijunjung as medicine. Of the 42 types of plants used, sitawa (Costus speciosus) is the most widely used plant in the treatment of fever. Almost all plants used as medicine are taken orally.
Pelatihan Identifikasi Cepat Fitokimia pada Mahasiswa STIFI BP Palembang Ferdian, Arif; Arifa, Nurwahidatul; Bakhtiar, Amri
ABDIKAN: Jurnal Pengabdian Masyarakat Bidang Sains dan Teknologi Vol. 2 No. 4 (2023): November 2023
Publisher : Yayasan Literasi Sains Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55123/abdikan.v2i4.2372

Abstract

Identification of phytochemicals is an important preliminary test that pharmacy students need to know and understand. As is known, that natural ingredients are an important aspect that plays a role in herbal medicine. One of the most prominent uses of plants is as a medicinal ingredient. In determining the traditional use of natural materials, it is necessary to know which groups of chemical compounds are contained in natural materials. Chemical compounds contained in natural products are grouped into alkaloids, phenolics, flavonoids, saponins, steroids and terpenoids. To determine the class of compounds in natural products, it is necessary to carry out preliminary tests quickly, namely by testing phytochemicals. Phytochemical identification training is aimed at STIFI Bhakti Pertiwi Palembang students who conduct field studies at Anai Land, Padang Pariaman Regency, Padang, West Sumatra. This field study activity is held as a support for natural product chemistry lectures. Phytochemical testing was carried out in groups guided by each. Students who have received training can carry out phytochemical testing of natural ingredients as a provision for final project research.
Antibacterial Potential Of Endophytic Fungi Isolated From Pachyrhizus Erosus (Bengkoang) Dwinatrana, Khiky; Lira, Fadilla; Rustini, Rustini; Arif, Ferdian
SITAWA : Jurnal Farmasi Sains dan Obat Tradisional Vol. 5 No. 1 (2026): SITAWA : Jurnal Farmasi Sains dan Obat Tradisional
Publisher : LPPM Akademi Farmasi Imam Bonjol Bukittinggi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62018/sitawa.v5i1.190

Abstract

The search for new antibacterial agents has increasingly focused on endophytic fungi, which inhabit plant tissues and may complement the bioactivity of their hosts. Pachyrhizus erosus (bengkoang), an edible legume rich in phenolics and flavonoids, remains underexplored as a reservoir of fungal endophytes with antibacterial potential. This study aimed to isolate endophytic fungi from P. erosus and evaluate their antibacterial properties. Tuber and leaf tissues were surface sterilized, yielding five isolates (PE1–PE5) that were cultured on rice medium, extracted with ethyl acetate, and tested against Staphylococcus aureus ATCC 29213 and Escherichia coli ATCC 25922 using the Kirby–Bauer disc diffusion method. All extracts inhibited bacterial growth, with PE2 showing the strongest activity (15.7 ± 1.40 mm for S. aureus and 14.4 ± 0.32 mm for E. coli). TLC profiling of PE2 extract revealed multiple spots under UV (254 and 366 nm), and phytochemical screening indicated the presence of phenolics and triterpenoids. Taken together, the results demonstrate that tuber-associated endophytic fungi of P. erosus are capable of producing antibacterial metabolites comparable to plant-derived compounds, underscoring their potential as sources of antimicrobial agents.
Chemical profiling of African leaves (Vernonia amygdalina Delile) and Kenikir leaves (Cosmos caudatus Kunth) extracts using Thin Layer Chromatography (TLC) Relin Yesika; Meridha Mutiara A; Nurwahidatul Arifa; Arif Ferdian; Miming Andika; Yahdian Rasyadi; Nana Liana; Erdanela Setiawati
JURNAL FARMASI DAN MAKANAN Vol 7 No 1 (2023): Journal of Pharmacy and Science
Publisher : LPPM Universitas Abdurrab

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36341/jops.v7i1.4103

Abstract

African leaves (Vernonia amygdalina Delile) and kenikir leaves (Cosmos caudatus Kunth) are plants that belong to the asteraceae family. Members of asteraceae have been used in food and medicine for centuries. This study aims to determine the secondary metabolite compounds contained in African leaves extracts and kenikir leaves through phytochemical screening using Thin-layer chromatography (TLC) method detected using UV 254nm and UV 366 nm light, as well as spot revealers that match the chemical group. The results of phytochemical screening using KLT show that African leaves contain flavonoids, terpenoids. And kenikir leaf extract is positive for steroids and flavonoids, one of them which is isocuesitrin.
Potensi Aktivitas Anti-tirosinase dari genus Citrus: Potensi Aktivitas Anti-tirosinase dari genus Citrus Arif Ferdian; Khiky Dwinatrana; Relin Yesika
JURNAL FARMASI DAN MAKANAN Vol 9 No 1 (2025): Journal of Pharmacy and Science
Publisher : LPPM Universitas Abdurrab

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36341/jops.v9i1.7022

Abstract

Skin hyperpigmentation is a common dermatological condition characterized by excessive melanin production, primarily regulated by the enzyme tyrosinase. Natural tyrosinase inhibitors have gained increasing interest as safer alternatives to synthetic depigmenting agents. This study aimed to evaluate and compare the tyrosinase inhibitory activity of peel extracts and solvent fractions of three Citrus species: C. aurantifolia, C. microcarpa, and C. hystrix. Extraction was carried out using Soxhlet and fractionation with n-hexane, ethyl acetate, and methanol. Tyrosinase inhibition was assessed using L-DOPA as the substrate. The results showed significant differences among species and fractions. The n-hexane fraction of C. hystrix exhibited the strongest activity (IC50 34.24 ppm), followed by C. microcarpa (144.05 ppm), while C. aurantifolia showed the weakest inhibitory effect across all fractions. The high potency of C. hystrix is associated with its rich monoterpene content, while lower activity in C. aurantifolia may relate to degradation of thermo-labile flavonoids during Soxhlet extraction. These findings highlight the potential of C. hystrix peel, particularly its non-polar fraction, as a promising natural tyrosinase inhibitor for cosmetic applications.
Analysis of Metabolite Profile of Gambier Flower (Uncaria gambir (Hunter) Roxb.) in Various Solvent Fractions Using LC-MS Arif Ferdian; Amri Bakhtiar; Suci Salwa Fitri Mustafa; Neny Sandrawati
Jurnal Pijar MIPA Vol. 21 No. 4 (2026): in Progress
Publisher : Department of Mathematics and Science Education, Faculty of Teacher Training and Education, University of Mataram. Jurnal Pijar MIPA colaborates with Perkumpulan Pendidik IPA Indonesia Wilayah Nusa Tenggara Barat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jpm.v21i4.11982

Abstract

The gambier plant is known as a rich source of secondary metabolites with biological activities, including anticancer, antioxidant, and antimicrobial properties. The leaves of the gambier plant are reported to contain flavonoids, including catechins, and tannins. This study aims to analyze the metabolite profile of gambier flowers using Liquid Chromatography-Mass Spectrometry (LC-MS). Gambier flower samples were extracted by maceration using ethanol as the solvent. The resulting macerate was then fractionated using n-hexane, ethyl acetate, and n-butanol. The gambier flower extracts were tested for phytochemical content via thin-layer chromatography (TLC) and analyzed for secondary metabolite content via LC-MS for each fraction. TLC testing of the total extract yielded positive results for flavonoids, steroids, phenolics, and alkaloids. Analysis of the secondary metabolite profile of the total extract identified 6 compounds from the 14 compound chromatograms that appeared; the n-hexane extract showed 6 compounds successfully identified from a total of 20 compounds, the ethyl acetate extract showed 6 identified compounds from 17 compounds, and the n-butanol extract contained 7 known compounds from 35 compounds. From the metabolite profile analysis, it can be concluded that gambier flowers contain numerous bioactive compounds with potential for further development and can serve as a source of new knowledge in exploring plant potential. To the best of our knowledge, this is the first LC-MS-based metabolite profile of gambier flowers, an organ that has remained largely unexplored compared with the widely studied leaves; the flowers display a greater diversity of flavonoid glycosides and phenolic derivatives, highlighting their novelty and their promise as antioxidant-rich raw materials for the pharmaceutical and cosmetic industries.
Co-Authors Amri Bakhtiar Amri Bakhtiar Arifa, Nurwahidatul Dwinatrana, Khiky Erdanela Setiawati Khiky Dwinatrana Lira, Fadilla Meiridha Mutiara Andania Meridha Mutiara A Miming Andika Nana Liana Neny Sandrawati Nurwahidatul Arifa Relin Yesika Relin Yesika Relin Yesika Rustini Rustini Suci Salwa Fitri Mustafa Yahdian Rasyadi