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All Journal Jurnal EduHealth International Journal of Health and Pharmaceutical (IJHP) The International Journal of Medical Science and Health Research The Indonesian Journal of General Medicine
Nur Aulia Amir
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Dentistry Health Professions Medicine & Pharmacology Nursing Public Health Veterinary

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 1 
Description of Visual Acuity and Refractive Arrangements in Patients Post Cataract Operation at Jec Orbita Makassar Eye Hospital in 2022 Yulia Nugra; Zulfikri Khalil Novriansyah; Hikmah Hiromi R; Nur Aulia Amir; Ruslinah, Ruslinah
Jurnal EduHealth Vol. 15 No. 02 (2024): Jurnal eduHealt, Edition April - June , 2024
Publisher : Sean Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Survey results show that the main cause of blindness is cataracts. The only definitive therapy for cataract patients is surgery. However, not all patients who have undergone surgery will achieve the desired visual improvement and therefore affect the patient's quality of life. To determine the description of visual acuity and refractive errors in patients after cataract surgery at the JEC-Orbita Makassar Eye Hospital in 2022. This research is a descriptive study with a cross sectional approach using secondary data from the medical records of patients who have had cataract surgery at the JEC Eye Hospital -Orbita Makassar in 2022. Results: Visual acuity at H+1 post-surgery mostly showed blind vision (32.3%), at H+7 post-surgery most showed normal vision (43%), and at H+30 post-surgery the majority showed normal vision (68.8%). The refractive errors found were 17.2% hypermetropia, 10.8% AHS, 9.7% AMS, 9.7% AM, 8.6% AHC, and 1.1% myopia. Conclusion: Visual acuity after cataract surgery shows significant improvement and continues to improve with increasing length of control time. Large parts of post-operative refractive error show hypermetropia, then AHS, AMS, AM, AHC and myopia sequentially.
Cytotoxicity Test of Green Betel Leaf Ethanol Extract (Piper Betle L.) Using Shrimp Larvae (Artemia Salina L.) Using The Brine Shrimp Lethality Test (BSLT) Method Ismail, Mardhiyah Adawiyah; Vitayani, Sri; Nur Aulia Amir; Yusriani Mangarengi; Marzelina Karim; Galagher, Mahry
International Journal of Health and Pharmaceutical (IJHP) Vol. 5 No. 1 (2025): February 2025 (Indonesia - Turkey - Malaysia - Australia - Iran)
Publisher : CV. Inara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51601/ijhp.v5i1.407

Abstract

The Brine Shrimp Lethality Test (BSLT) method is a preliminary method for screening anticancer compounds by looking at the cytotoxic effect of a sample that will be tested on Artemia salina shrimp larvae. This study aims to evaluate the cytotoxic effect of ethanol extract of green betel leaves (Piper betle L.) on Artemia salina Leach larvae using the Brine Shrimp Lethality Test (BSLT) method. Extraction was carried out by maceration method using 96% ethanol, and phytochemical screening to show the presence of secondary metabolite on green betel leef. Cytotoxicity tests were carried out at five extract concentrations (concentrations of 50 ppm, 100 ppm, 250 ppm, 500 ppm, and 750 ppm). Based on the results of the research carried out, it can be concluded that the results show that the percentage of larvae deaths ranges from 30-80% and the highest mortality was obtained at a concentration of 750 ppm with a total of 26 larval deaths, this death was in line with the increase in concentration. The Lethal Concentration (LC50) value obtained was 121.3317 ppm. In conclusion, green betel leaf extract contains secondary metabolite compounds which cause cytotoxic effects on Artemia salina Leach shrimp larvae with a mortality percentage of 30-80% and the LC50 value is 121.3317 ppm.
Literature Review : Manifestation Ocular Pada Penyakit Tiroid Balgis Dhea Permatasari; Nur Aulia Amir; Andi Faridah Amien; Abdul Mubdi; Ratih Natasha
The Indonesian Journal of General Medicine Vol. 13 No. 4 (2025): The Indonesian Journal of General Medicine
Publisher : International Medical Journal Corp. Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.70070/rtk32413

Abstract

Thyroid Eye Disease (TED) atau oftalmopati Graves merupakan manifestasi okular dari gangguan tiroid autoimun, terutama pada penyakit Graves. Kajian ini bertujuan untuk mengidentifikasi karakteristik klinis, faktor risiko, dan penatalaksanaan pada TED melalui tinjauan terhadap lima studi primer. Hasil menunjukkan bahwa manifestasi TED dapat terjadi pada pasien hipertiroid maupun eutiroid, dengan gejala seperti proptosis, retraksi kelopak mata, dan gangguan motilitas okular. Kadar TRAb tinggi dan aktivitas penyakit terbukti berhubungan erat dengan keparahan TED, sementara faktor klasik seperti usia, jenis kelamin, dan merokok tidak selalu signifikan. Penatalaksanaan yang efektif termasuk pemberian metilprednisolon intravena, dengan tambahan terapi multimodal pada kasus berat atau refrakter. Hasil tinjauan ini menekankan pentingnya pendekatan diagnostik dan terapetik yang terintegrasi serta deteksi dini untuk mencegah komplikasi penglihatan.
Katarak Pada Pasien Diabetes Mellitus Brigischa Febrilia AP; Suliati P Amir; Nur Aulia Amir; Zulfikri Khalil Novriansyah; Ariyanie Nurtania
The Indonesian Journal of General Medicine Vol. 14 No. 1 (2025): The Indonesian Journal of General Medicine
Publisher : International Medical Journal Corp. Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.70070/d6kpjm10

Abstract

Latar Belakang: Diabetes Mellitus (DM) merupakan penyakit metabolik kronis yang berpotensi menimbulkan komplikasi mikrovaskular, salah satunya adalah katarak. Dibandingkan populasi non-diabetik, penderita DM memiliki risiko 2–5 kali lebih tinggi mengalami katarak, yang dapat berkembang lebih cepat dan pada usia yang lebih muda. Mekanisme utama yang mendasari pembentukan katarak pada DM antara lain adalah akumulasi sorbitol melalui jalur poliol dan stres oksidatif yang menyebabkan kerusakan serat lensa. Metode: Penelitian ini merupakan narrative literature review yang bertujuan mengidentifikasi dan menganalisis artikel ilmiah terkait hubungan antara diabetes mellitus dan risiko katarak. Literatur diperoleh melalui pencarian sistematis pada database ilmiah. Total 14 artikel dipilih berdasarkan kriteria inklusi, dengan lima artikel utama dianalisis lebih dalam. Hasil: Review menunjukkan prevalensi katarak yang tinggi pada pasien DM, berkisar antara 42–70%, dengan jenis katarak yang paling sering adalah subkapsular posterior dan kortikal. Faktor risiko yang konsisten ditemukan mencakup kontrol glikemik buruk (HbA1c tinggi), durasi DM lebih dari 10 tahun, usia lanjut, dan keberadaan retinopati diabetik. Studi juga menunjukkan hubungan antara hipertensi, hiperlipidemia, serta neuropati diabetik dengan kejadian katarak. Kesimpulan: Terdapat hubungan signifikan antara diabetes mellitus dan peningkatan risiko katarak. Faktor metabolik dan sistemik turut mempercepat proses kekeruhan lensa. Oleh karena itu, manajemen DM yang optimal, pemeriksaan mata berkala, serta edukasi pasien merupakan langkah penting untuk mencegah gangguan penglihatan yang lebih lanjut.
The Relationship between Obesity and The Incidence of Gastroesophageal Reflux Disease (GERD) Puput S; Syamsu Rijal; Nur Aulia Amir
The International Journal of Medical Science and Health Research Vol. 15 No. 3 (2025): The International Journal of Medical Science and Health Research
Publisher : International Medical Journal Corp. Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.70070/nc66cm88

Abstract

Background: Gastroesophageal Reflux Disease (GERD) is an upper gastrointestinal disorder frequently associated with obesity. The prevalence of both GERD and obesity continues to rise in Indonesia, highlighting the importance of understanding their epidemiological relationship to support prevention and management strategies. Methods: This study is a narrative literature review that identifies and analyzes scientific publications from 2020–2025 regarding the relationship between obesity and the incidence of GERD in Indonesia. Literature was searched through PubMed, ScienceDirect, Google Scholar, and Garuda Ristek-BRIN using relevant keywords. Empirical and relevant articles were selected and analyzed qualitatively. Results: The majority of studies found a significant association between increased Body Mass Index (BMI) and the risk of GERD. The main mechanisms include increased intra-abdominal pressure due to visceral fat accumulation and dysfunction of the lower esophageal sphincter (LES), which facilitates gastric acid reflux. Some studies reported an odds ratio for GERD risk in obese individuals reaching up to 9.44 times compared to those with normal weight. Additionally, high-calorie and high-fat diets were shown to exacerbate GERD symptoms. Although some studies reported less significant findings, the general consensus supports obesity as a major risk factor for GERD. Conclusion: Obesity significantly increases the risk of GERD through physiological and hormonal mechanisms. Therefore, weight management through lifestyle modification and nutritional intervention is a crucial strategy for the prevention and treatment of GERD in the adult population in Indonesia.
Co-Authors Abdul Mubdi Andi Faridah Amien Ariyanie Nurtania Balgis Dhea Permatasari Brigischa Febrilia AP Galagher, Mahry Hikmah Hiromi R Ismail, Mardhiyah Adawiyah Marzelina Karim Puput S Ratih Natasha Ruslinah, Ruslinah Sri Vitayani Suliati P Amir Syamsu Rijal Yulia Nugra Yusriani Mangarengi Zulfikri Khalil Novriansyah