Garuda - Garba Rujukan Digital

Effect of Andaliman (Zanthoxylum Acanthopodium DC) Extracts on The Histological Display of Lewy Body in The Brain of Rotenone Induced Wistar Rats Afina, Lubna; Halim, Binarwan; Chiuman, Linda; Anggraeni, Wenti; Rizki, Kartika Sari
International Journal of Islamic Education, Research and Multiculturalism (IJIERM) Vol 6 No 3 (2024)
Publisher : The Islamic Education and Multiculturalism Foundation

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47006/ijierm.v6i3.408

Dementia Lewy Body (DLB) is a form of dementia characterized by abnormal accumulation of α-synuclein protein in the brain, forming lewy bodies that damage the function of neurons and nervous system. This study aimed to evaluate the effect of andaliman fruit extract (Zanthoxylum Acanthopodium DC), which is rich in antioxidants, on the number of lewy bodies in the brain of rotenone-induced Wistar male rats. Histology analysis was performed to observe the number of lewy bodies in the brain. The results showed a significant decrease in the number of lewy bodies in the treatment group compared to the positive control group (p<0.05). Increasing the dose of andaliman extract was directly proportional to the decrease in the number of lewy bodies, with the highest dose (450 mg/kgBB) providing the best protective effect. These findings suggest that the antioxidant content in andaliman extract can neutralize the oxidative stress caused by rotenone, thus protecting neurons from damage. This study supports the development of andaliman extract as an alternative therapy to prevent or inhibit the progressivity of DLB.

Effectiveness of stretching on reducing muscle and bone pain in worker Siagian, Masryna; Butar-Butar, Emely Thania; Rizki, Kartika Sari; Artiani, Litri; Siregar, Ryskina Fatimah; Putri, Disti Amanda
Buletin Kedokteran & Kesehatan Prima Vol. 4 No. 1 (2025): March
Publisher : Fakultas Kedokteran, Kedokteran Gigi, dan Ilmu Kesehatan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.34012/bkkp.v4i1.6547

Musculoskeletal pain is a common work-related ailment in Indonesia. Although not fatal, it can significantly reduce worker productivity. Stretching exercises are often used to alleviate this pain. Pre-work stretching and warm-up exercises may reduce the risk of musculoskeletal pain and fatigue, improve muscle balance and posture, and promote muscle relaxation by lengthening tense muscles, thus increasing comfort during work. This study aimed to determine the effectiveness of stretching in reducing musculoskeletal pain among workers at the Opak Suli Factory in Sukaraya Bakti Village, Pancur Batu District, Deli Serdang Regency. The experimental study employed a pre-test and post-test control group design. All 38 workers at the Opak Suli Factory in Sukaraya Bakti Village, Pancur Batu District, Deli Serdang Regency, were included using total sampling and divided into an intervention group and a control group, each consisting of 19 workers. The intervention group showed a statistically significant reduction in musculoskeletal pain (p < 0.001), indicating that stretching was effective. In contrast, the control group showed no significant change (p = 0.083). In conclusion, stretching is an effective method for reducing musculoskeletal pain among the workers in this study.

PENGARUH PEMBERIAN KRIM EKSTRAK KULIT KAYU MANIS (CINNAMOMUM BURMANNII) TERHADAP PENINGKATAN JUMLAH FIBROBLAS KULIT DALAM PENYEMBUHAN LUKA BAKAR PADA TIKUS PUTIH JANTAN GALUR Herwanto, Syaputra Adhi; Rosari, Anita; Rizki, Kartika Sari
PREPOTIF : JURNAL KESEHATAN MASYARAKAT Vol. 9 No. 1 (2025): APRIL 2025
Publisher : Universitas Pahlawan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/prepotif.v9i1.41178

Penelitian ini dilakukan untuk menguji dan menganalisis pengaruh pemberian krim ekstrak kulit kayu manis (Cinnamomum burmannii) terhadap peningkatan jumlah fibroblas pada tikus putih (Rattus norvegicus) jantan galur wistar yang mengalami luka bakar. Jenis penelitian yang digunakan pada penelitian ini yaitu kuantitatif eksperimental dengan menggunakan desain true experiment atau eksperimental laboratorium. Penelitian eksperimen dilaksanakan dengan mengontrol semua variabel luar yang dapat mempengaruhi kegiatan eksperimen. Penelitian ini menggunakan post-test only control group design untuk mengetahui dan menganalisis efek pemberian ekstrak kulit kayu manis dalam mempercepat penyembuhan luka dan pembentukan jaringan fibroblas pada tikus putih (Rattus norvegicus) galur wistar yang mengalami luka bakar. Hasil uji fitokimia menunjukkan bahwa ekstrak kulit kayu manis (Cinnamomum burmannii) mengandung metabolit sekunder berupa flavonoid, tannin, saponin, alkaloid, dan triterpenoid. Pemberian krim ekstrak kulit kayu manis (Cinnamomum burmannii) dengan konsentrasi 4%, 6%, dan 8% dapat mempercepat penyembuhan luka bakar dan meningkatkan pertumbuhan fibroblas pada tikus putih galur wistar. Krim ekstrak kulit kayu manis (Cinnamomum burmannii) dengan konsentrasi 8% paling efektif dalam mempercepat penyembuhan luka, yaitu dalam 12 hari. Hasil pengamatan gambaran histopatologi jaringan kulit menunjukkan pertumbuhan fibroblas kelompok perlakuan 1, 2, dan 3 dengan pemberian krim ekstrak kulit kayu manis (Cinnamomum burmannii) dengan konsentrasi 4%, 6%, dan, 8% lapisan epidermis sudah terbentuk secara sempurna dan tidak ditemukan penebalan pada lapisan epidermis dibanding kelompok kontrol yang hnnya mulai terbentuk lapisan epidermis.

Prevalence and Associated Risk Factors of Dehydration Among Construction Workers Rizki, Kartika Sari; Siregar, Santy Deasy; Akasna, Ezra Tri Mutiara; Aulia, Annisa
Jurnal Kesmas Prima Indonesia Vol. 9 No. 2 (2025): July Edition
Publisher : Program Studi Sarjana Kesehatan Masyarakat Universitas Prima Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.34012/jkpi.v9i2.7374

Dehydration poses a significant health risk to construction workers due to heavy physical work and exposure to hot working conditions. This study aimed to determine the prevalence of dehydration and identify associated risk factors among construction workers. A cross-section study was conducted involving 32 construction workers in a construction project for the construction of a wheat flour and soybean mill owned by PT. Agri First which operates at KIM 2 Medan. Data were collected using questionnaires, fingertip pulse oximeters, urine refractometers, and observation sheets. Dehydration is categorized based on the level of urine specific gravity (ultrasound). The data was statistically tested using the Fisher Exact test (α=0.05). The majority of workers (75%) were dehydrated. There was no significant relationship between dehydration and age. However, workers with more than 3 years of experience were more likely to be dehydrated compared to workers with less than 3 years of experience (OR = 8,333, 95% CI: 1,392-49,872). Workers with moderate workloads were also more likely to be dehydrated compared to workers with light workloads (OR = 18,333). There was a significant association between water intake and dehydration (p = 0.000). All workers who did not drink enough water were dehydrated, while only 66.7% of those who drank enough water were dehydrated. Workers with more than 3 years of experience, moderate workload, and inadequate water intake have a higher risk of becoming dehydrated. Interventions to improve hydration among construction workers are urgently needed.

Effectiveness of stretching on reducing muscle and bone pain in worker Siagian, Masryna; Butar-Butar, Emely Thania; Rizki, Kartika Sari; Artiani, Litri; Siregar, Ryskina Fatimah; Putri, Disti Amanda
Buletin Kedokteran & Kesehatan Prima Vol. 4 No. 1 (2025): March
Publisher : Fakultas Kedokteran, Kedokteran Gigi, dan Ilmu Kesehatan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.34012/bkkp.v4i1.6547

Musculoskeletal pain is a common work-related ailment in Indonesia. Although not fatal, it can significantly reduce worker productivity. Stretching exercises are often used to alleviate this pain. Pre-work stretching and warm-up exercises may reduce the risk of musculoskeletal pain and fatigue, improve muscle balance and posture, and promote muscle relaxation by lengthening tense muscles, thus increasing comfort during work. This study aimed to determine the effectiveness of stretching in reducing musculoskeletal pain among workers at the Opak Suli Factory in Sukaraya Bakti Village, Pancur Batu District, Deli Serdang Regency. The experimental study employed a pre-test and post-test control group design. All 38 workers at the Opak Suli Factory in Sukaraya Bakti Village, Pancur Batu District, Deli Serdang Regency, were included using total sampling and divided into an intervention group and a control group, each consisting of 19 workers. The intervention group showed a statistically significant reduction in musculoskeletal pain (p < 0.001), indicating that stretching was effective. In contrast, the control group showed no significant change (p = 0.083). In conclusion, stretching is an effective method for reducing musculoskeletal pain among the workers in this study.

Prevalence and Associated Risk Factors of Dehydration Among Construction Workers Rizki, Kartika Sari; Siregar, Santy Deasy; Akasna, Ezra Tri Mutiara; Aulia, Annisa
Jurnal Kesmas Prima Indonesia Vol. 9 No. 2 (2025): July Edition
Publisher : Program Studi Sarjana Kesehatan Masyarakat Universitas Prima Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.34012/jkpi.v9i2.7374

Dehydration poses a significant health risk to construction workers due to heavy physical work and exposure to hot working conditions. This study aimed to determine the prevalence of dehydration and identify associated risk factors among construction workers. A cross-section study was conducted involving 32 construction workers in a construction project for the construction of a wheat flour and soybean mill owned by PT. Agri First which operates at KIM 2 Medan. Data were collected using questionnaires, fingertip pulse oximeters, urine refractometers, and observation sheets. Dehydration is categorized based on the level of urine specific gravity (ultrasound). The data was statistically tested using the Fisher Exact test (α=0.05). The majority of workers (75%) were dehydrated. There was no significant relationship between dehydration and age. However, workers with more than 3 years of experience were more likely to be dehydrated compared to workers with less than 3 years of experience (OR = 8,333, 95% CI: 1,392-49,872). Workers with moderate workloads were also more likely to be dehydrated compared to workers with light workloads (OR = 18,333). There was a significant association between water intake and dehydration (p = 0.000). All workers who did not drink enough water were dehydrated, while only 66.7% of those who drank enough water were dehydrated. Workers with more than 3 years of experience, moderate workload, and inadequate water intake have a higher risk of becoming dehydrated. Interventions to improve hydration among construction workers are urgently needed.

Title

Found 6 Documents
Search

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Title Search

Found 6 Documents Search

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Title

Found 6 Documents
Search