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All Journal Jurnal Cendekia : Jurnal Pendidikan Matematika JKKI : Jurnal Kedokteran dan Kesehatan Indonesia CoMPHI Journal : Community Medicine and Public Health of Indonesia Journal International Journal of Health and Information System (IJHIS)
sulihah, nurfaizah titisari
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Computer Science & IT Education Health Professions Library & Information Science Mathematics Medicine & Pharmacology Nursing Public Health

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The Correlation Between Low Birth Weight And Stunting Incidence In Balet Baru Village, Sukowono District, Jember Regency Rachmawati, Dwita Aryadina; Normasari, Rena; Nurmaida, Eny; Hakiim, Arsyzilma; Sudarmanto, Yohanes; Parti, Dita Diana; Sofiana, Kristianningrum Dian; Astuti, Ida Srisurani Wiji; Putri, Elvia Rahmi Marga; Sulihah, Nurfaizah Titisari
International Journal of Health and Information System Vol. 3 No. 1 (2025): May
Publisher : Indonesian Journal Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47134/ijhis.v3i1.69

Abstract

Stunting is an indicator of chronic nutritional disorders and is still a complex public health problem. One of the direct risk factors for stunting is Low Birth Weight (LBW). This study is an analytical observational study that aims to determine the correlation between the history of Low Birth Weight (LBW) and the incidence of stunting in toddlers. The research was carried out in Balet Baru Village, Sukowono District, Jember Regency. The population in this study were all children aged 6 months to 5 years who are recorded in the Maternal and Child Health (KIA) register in Balet Baru Village. The total number of research subjects was 168 toddlers in a case-control design. Bivariate analysis is used to determine the relationship between LBW history and stunting incidence using the Chi-Square test. The results of the analysis showed a p-value of 0.002 (p < 0.05), which means that there is a statistically significant correlation between the history of LBW and the incidence of stunting in children aged 6 months to 5 years. An odds ratio (OR) value of 4.640 shows that children with a history of LBW have a 4.64 times greater risk of stunting than children without a history of LBW.
Proses Metakognisi dalam Interaksi Siswa pada Diskusi Kelompok Firmansyah, Frenza Fairuz; Yudianto, Erfan; Febrianto, Eko Yudi; Sulihah, Nurfaizah Titisari; Budianto, Trio Rhoma
Jurnal Cendekia : Jurnal Pendidikan Matematika Vol 9 No 2 (2025): Jurnal Cendekia: Jurnal Pendidikan Matematika Volume 9 Nomor 2 Tahun 2025
Publisher : Mathematics Education Study Program

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/cendekia.v9i2.3964

Abstract

Proses metakognisi berperan penting dalam mendukung interaksi siswa selama diskusi kelompok. Diskusi kelompok memungkinkan siswa bekerja sama untuk mencapai pemahaman yang lebih mendalam terhadap suatu konsep dengan saling bertukar ide dan strategi pemecahan masalah. Penelitian ini bertujuan untuk menganalisis proses metakognisi yang muncul dalam interaksi siswa selama diskusi kelompok. Metode penelitian yang digunakan yaitu penelitian kualitatif pendekatan penelitian deskripif dengan menganalisis pembelajaran siswa dalam diskusi kelompok. Subjek penelitian terdiri dari enam siswa dalam satu kelompok, dengan fokus utama pada siswa yang berperan sebagai siswa ahli yang ditinjau dari teori pemosisian siswa. Hasil penelitian menunjukkan bahwa siswa ahli cenderung menerapkan strategi metakognitif reflective use dalam setiap langkah pemecahan masalah. Kemampuan metakognitif menjadi faktor kunci dalam diskusi kelompok. Siswa yang memiliki keterampilan metakognitif lebih baik mampu mengarahkan jalannya diskusi, meningkatkan rasa percaya diri, dan membantu anggota kelompok memahami materi dengan lebih efektif. Kesadaran akan proses berpikir sendiri memungkinkan siswa untuk mengoptimalkan strategi belajar dalam menyelesaikan masalah secara kolaboratif. Rekomendasi dari hasil penelitia ini yaitu pendidik sebaiknya mendorong implementasi strategi reflective use dalam diskusi kelompok, khususnya dengan memfasilitasi peran siswa ahli untuk membimbing anggota kelompok lainnya.
Uji Aktivitas Antibakteri Senyawa Bawang Putih (Allium Sativum L.) secara In Silico Terhadap Bakteri Streptococcus Pneumoniae Sulihah, Nurfaizah Titisari; Baidowi, Ivan Iqbal; Firdaus, Jauhar; Wulan, Herlina Nur
CoMPHI Journal: Community Medicine and Public Health of Indonesia Journal Vol. 5 No. 3 (2025): Februari
Publisher : Perhimpunan Dokter Kedokteran Komunitas dan Kesehatan Masyarakat Indonesia (PDK3MI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37148/comphijournal.v5i3.297

Abstract

Streptococcus pneumoniae is a pathogenic bacterium and one of the leading causes of pneumonia. The first-line therapy for pneumonia typically involves the administration of empirical antibiotics. However, excessive use of antibiotics has triggered resistance to various drugs, highlighting the need for new, potential alternatives with antibacterial activity. In this context, traditional medicinal plants with antibiotic-like properties can be considered, one of which is garlic (Allium sativum L.), known to contain active compounds with antibacterial effects. The objective of this study was to identify the most potent active compound in garlic (Allium sativum) as an antibacterial agent against S. pneumoniae. The method used was an in silico test via molecular docking between garlic’s active compounds and the bacterial target protein, penicillin-binding protein 2 (PBP2). The results showed that the active compounds allicin, ajoene, S-allylcysteine, and alliin have antibacterial potential, with alliin showing the highest potential among them although still lower than the antibiotic benzylpenicillin. This study is based on in silico analysis and therefore requires further experimental validation.
Caspase-3 modulation by Cinnamomum burmannii extract attenuates pancreatic damage in diabetic rats: An in silico and in vivo study Sulihah, Nurfaizah Titisari; Mufida, Diana Chusna; Akbar, Anandiya Dzakyfikri Dzikrullah; Baidowi, Ivan Iqbal
JKKI : Jurnal Kedokteran dan Kesehatan Indonesia JKKI, Vol 17, No 2, (2026)
Publisher : Faculty of Medicine, Universitas Islam Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20885/JKKI.Vol17.Iss2.art2

Abstract

Background: Diabetes mellitus is characterized by hyperglycaemia resulting from impaired insulin secretion or action. This condition may trigger oxidative stress leading to apoptosis, mediated by caspase-3. Pancreatic tissue damage caused by apoptosis contributes to diabetes progression. Cinnamomum burmannii extract is known to contain bioactive compounds with antioxidant and antiapoptotic properties, which may provide protective effects on pancreatic tissue.Objectives: This study aimed to evaluate the potential of C. burmannii extract in modulating caspase-3 in pancreatic diabetic rats through both in silico and in vivo studies.Method: The in silico study was conducted using molecular docking analysis to evaluate the binding affinity and interaction patterns of active compounds from C. burmannii with Caspase-3 as the target protein involved in apoptosis using pyRx, with visualization in Discovery Studio. The in vivo study used streptozotocin-induced diabetic male Wistar rat, which were randomly divided into four groups (normal control group, DM group, DM group treated with C. burmannii extract 100 mg/kg BW, DM group treated with CB extract 200 mg/kg BW). The pancreatic tissue was collected, and the Caspase-3 expression was evaluated using immunohistochemical staining. The obtained data were analysed using SPSS Statistics with one-way ANOVA and Pearson correlation coefficient, with p < 0.05 considered significant.Results: The in silico analysis demonstrated that epicatechin compounds have a strong binding affinity with the active site of caspase-3. Then the in vivo analysis indicated that administration of C. burmannii extract significantly reduced caspase-3 expression in the pancreas of the diabetic rats compared to the control group.Conclusion: C. burmannii extract has potential as an antiapoptotic agent through caspase-3 modulation. These findings provide scientific evidence supporting the promising role of C. burmannii as an adjunctive therapeutic agent in diabetes management.
Co-Authors Akbar, Anandiya Dzakyfikri Dzikrullah Arsyzilma Hakiim Baidowi, Ivan Iqbal Budianto, Trio Rhoma Diana Chusna Mufida Dita Diana Parti Dwita Aryadina Rachmawati Erfan Yudianto Febrianto, Eko Yudi Firmansyah, Frenza Fairuz Ida Srisurani Wiji Astuti Jauhar Firdaus Kristianningrum Dian Sofiana Nurmaida, Eny Putri, Elvia Rahmi Marga Rena Normasari Sudarmanto, Yohanes Wulan, Herlina Nur