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All Journal Jurnal RESTI (Rekayasa Sistem dan Teknologi Informasi) Jurnal Kedokteran Anatomica (Anatomica Medical Journal) JURNAL IBNU SINA BIOMEDIKA Buletin Farmatera Hasil Pengabdian Kepada Masyarakat Majalah Patologi Indonesia Jurnal Kesehatan Panrita Husada JURNAL ILMIAH MAKSITEK JURNAL ILMIAH SIMANTEK JURNAL ILMIAH KOHESI Budapest International Research in Exact Sciences (BirEx Journal) Jurnal Pandu Husada Jurnal Kesehatan Republik Indonesia JIMKI: Jurnal Ilmiah Mahasiswa Kedokteran Indonesia Jurnal Pengabdian Ilmu Kesehatan Jurnal Implementa Husada (JIH)
Des Suryani
UNIVERSITAS MUHAMMADIYAH SUMATERA UTARA
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GAMBARAN FOTO TORAKS PASIEN PENYAKIT PARU YANG MENGALAMI HEMOPTISIS PERIODE FEBRUARI - JUNI 2018 DI RSUD DR. PIRNGADI MEDAN RIZKY NURDIANTY; IKHFANA SYAFINA; DEDY DWI PUTRA; DES SURYANI
JURNAL ILMIAH SIMANTEK Vol 5 No 3 (2021): JURNAL ILMIAH SIMANTEK
Publisher : LP2MTBM MAKARIOZ

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Abstract

Hemoptysis is a symptom of removal of blood from mouths that are filled with a feeling of wanting to cough hematemesis ablood drain, black which is not and weal. To find out the picture of the chest X ray of patients with pulmonary disease whoexperienced symptoms of hemotysis in February 2018 – june 2018 at Dr. Pirngadi Medan. The type to be used in thisresearch is descriptive research and cross sectional research design. study. Population is patient of polyclinic of lung atRSUD Dr. Pirngadi Medan. The sample in this study is the medical record data from febuary 2018 – june 2018 in patients inthe pulmonary clinic RSUD Dr. Pirngadi Medan. The results of chest X-ray images in lung patients with most hemoptysissymptoms were infiltrates of 40 (75.5), the most gender who experience symptoms of hemoptysis are men as many as 40(75.5%), the highest age who experience symptoms of hemoptysis is 21-30 years as many as 22 (41.5%), the most lungdiagnosis of hemoptysis is 30 pulmonary tuberculosis (56.6%). There is a picture of chest X-ray infiltrates more common inlung disease patients with hemoptysis symptoms.
Comparison between Ocimum Sanctum Hepatoprotector Extract and Curcuma Xanthorrhiza on the Histological Structure of Aspartame-Induced Wistar Rats Des Suryani; Humairah Medina Liza Lubis
Budapest International Research in Exact Sciences (BirEx) Journal Vol 1, No 4 (2019): Budapest International Research in Exact Sciences, October
Publisher : Budapest International Research and Critics University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33258/birex.v1i4.476

Abstract

The use of aspartame is still controversial, because there are studies stating that aspartame is safe to use, and there are studies suggesting aspartame has the potential to damage the liver, but aspartame has been approved by the FDA and BPOM in Indonesia with a daily dose of 50 mg / kg / day, the level of public knowledge we are still low to allow this dose to be overtaken, coupled with the presence of several food products that do not include the content of aspartame, basil leaves have been known to have hepatoprotector effect, but the dosage is still varied, and no researchers have compared curcuma Xanthoriza which is herbal medicine that has been quite well accepted in the community, Objective: to compare the hepatoprotector effect of basil leaf extract with xanthoriza curkuma, Method: Laboratory experimental study with posttest only with control group design. Wistar rats were divided into 5 groups and treated for 30 days. This study analyzed the histopathology of liver using paraffin histotechnics blocks, with HE staining and light microscopy. Analysis of degeneration degree using Kruskal-walis analysis post Hoc Mann-Whitney Results showed an increase in the degree of degeneration in the aspartame group at a dose of 100 mg / kgbb / day (p <0.05) compared to the normal group and treatment. Use of aspartame past the ADI dose damaged the liver, kurkuma and basil leaf extract at a dose of 300 mg / kg has the same protective effect on aspartame-induced rat liver, conclusions: aspartame is toxic for the liver, the use of basil leaf extract at a dose of 300 mg / kg / day or kurkuma xhantoriza extract can reduce the toxicity of aspartame.
Minuman Berenergi Mengandung Aspartam Merusak Hepar Tikus Jantan (Rattus Norvegicus L) Zakiya Rafwiani; Des Suryani
ANATOMICA MEDICAL JOURNAL | AMJ Vol 1, No 1 (2018)
Publisher : Universitas Muhammadiyah Sumatera Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (327.661 KB) | DOI: 10.30596/anatomica

Abstract

Latar Belakang: Minuman berenergi yang mengandung aspartam biasa dikonsumsi oleh masyarakat.Penggunaan aspartam dalam minuman menimbulkan kontroversi mengenai keamanannya terhadap hati.Tujuan: Penelitian ini bertujuan untuk mengetahui pengaruhminuman berenergi mengandung aspartam sesuai dosis Acceptable Daily IntakeADI dan dosis melebihi ADI terhadap gambaran histopatologi hepar tikus jantan (Rattus norvegicus L.).Metode: Penelitian eksperimental invivo pada tikus dengan posttest only with control group design. Tikus dibagi menjadi 5 kelompok yaitu kelompok kontrol negatif (KN) yang hanya diberi aquades, kontrol positif 1 (KP1) yang diberi aspartam dosis ADI (50mg/kgbb/hari), kontrol positif 2 (KP2) yang diberi aspartam dosis toksik (75mg/kgbb/hari), perlakuan 1(P1) yang diberi minuman berenergi dosis ADI aspartam (50mg/kgbb/hari), dan perlakuan 2(P2) yang diberi minuman berenergi dosis aspartam (75mg/kgbb/hari). dan diberi perlakuan selama 28 hari. Histopatologi hepar dianalisis secara kualitatif. Data derajat degenerasi hepar dianalisis menggunakan uji Kruskal-walis dan uji post Hoc Mann-Whitney.Hasil: Pemberian minuman berenergi mengandung aspartam menimbulkan degenerasi hidrofik sel hepatosit. Ada perbedaan tingkat kerusakan hepar antara tikus yang diberi aspartam dosis ADI dengan tikus yang diberi aspartam melebih dosis ADI (p<0,05).Tidak ada perbedaan tingkat kerusakan hepar antara tikus yang diberi aspartam dosis melebihi ADI dengan tikus yang diberikan minuman berenergi yang mengandung aspartam baik pada dosis ADI maupun dosis melebihi disis ADI(p>0,05). Kesimpulan: , minuman berenergi mengandung aspartam menimbulkan degenerasi hidrofik hepar tikus jantan. Kandungan lain dalam minuman berenergi mungkin memperberat kondisi degenerasi hidrofik pada hepar tikus yang diberi minuman berenergi sesuai dosis ADI,apalagi bila diberikan dalam dosis yang melebihi dosis ADIKata kunci: Minuman berenergi, aspartam, histopatologi, hepar
PENGARUH PEMBERIAN MINUMAN BERENERGI YANG MENGANDUNG ASPARTAM TERHADAP GAMBARAN HISTOPATOLOGI RENAL TIKUS JANTAN (Rattus norvegicus L.) Cindy Mentari; Des suryani
ANATOMICA MEDICAL JOURNAL | AMJ Vol 1, No 3 (2018)
Publisher : Universitas Muhammadiyah Sumatera Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (151.776 KB) | DOI: 10.30596/anatomica

Abstract

ABSTRACTBackground: Energy drinks containing aspartame are commonly consumed by the public, the use of aspartame in energy drinks causes controversy regarding its safety against kidneys especially when consumed in excess. Objective: This study aimed to determine the effect of energy drinks containing aspartame on histopathology renal male rats (Rattus norvegicus L .) ". Method: Invivo experimental study on mice with posttest only with control group design. Rats were divided into 5 groups: negative control group (KN) which was only given aquades, positive control 1 (KP1) given ADI dose aspartame (50 mg / kg / day), positive control 2 (KP2) given toxic dose aspartame (75 mg / kgbb / day), treatment 1 (P1) given ADI dose of energy drinks aspartame (50 mg / kg / day), and treatment 2 (P2) given doses of aspartame doses of energy (75 mg / kg / day). and treated for 28 days. Renal histopathology was analyzed qualitatively. Glomerular and tubulus proximal degeneration degree data were analyzed using the Kruskal-walis test and Mann-Whitney post Hoc test. Results: Giving energy drinks containing aspartame caused glomerular and renal proximal tubular degeneration. There is a difference in the level of kidney damage between mice given ADI dose aspartame and mice given aspartame exceeding the ADI dose (p <0.05). There was no difference in the level of proximal tubular damage between mice given aspartame doses in excess of ADI with mice given energy drinks contains aspartame both at ADI doses and in doses exceeding the ADI level (p> 0.05). Conclusion: Energy drinks containing aspartame cause hydrophic degeneration in the glomerulus and proximal tubules of male rats. Other contents in energy drinks may aggravate the conditions of hydrophic degeneration in the glomerular and proximal tubular of  rat that are given energy drinks according to ADI doses, especially if given in doses that exceed ADI doses 
Meningkatkan Kesadaran Masyarakat Pentingnya Vaksinasi Covid 19 Di Kelurahan Pejuang, Jawa Barat Octari Auliati; Des Suryani; Nanda Sari Nuralita
JURNAL PRODIKMAS Hasil Pengabdian Kepada Masyarakat Vol 7, No 1 (2022)
Publisher : Universitas Muhammadiyah Sumatera Utara

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Abstract

Vaksinasi COVID-19 masih kontroversi di masyarakat, sebagian sudah memiliki kesadaran yang tinggi, namun sebagian masih takut karena mendapat informasi yang salah, dan sebagian lagi mau divaksin karena takut tidak di izinkan masuk mall, hal ini menjadi masalah yang dihadapi pemerintah, terutama di Kelurahan Pejuang ini. Dalam KKN ini saya berinisiatif untuk memberikan penyuluhan kepada masyarakat secara online melalui whatsApp. KKN dengan memberikan informasi berkaitan Vaksinasi. Penyuluhan Vaksinasi COVID-19 menggunakan Microsoft PowerPoint dimulai dari penjelasan hingga diskusi tanya jawab. Tanya jawab sangat penting bagi peserta. Kegiatan ini memungkinkan dapat meningkatkan kesadaran dan wawasan pentingnya Vaksinasi COVID-19 di masa pandemi saat ini. Hasil kegiatan ini menunjukkan bahwa masyarakat Kelurahan Pejuang antusias dan ada interaksi positif dari awal sampai akhir kegiatan berlangsung.
Sholat Dhuha May Reduce The Risk of Knee Osteoarthritis in The Elderly: Preliminary Research Elman Boy; Des Suryani; Debby Mirani Lubis; Balemun Kaisar Harahap
Buletin Farmatera Vol 7, No 3 (2022)
Publisher : Universitas Muhammadiyah Sumatera Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30596/bf.v7i3.11939

Abstract

Abstract: Osteoarthritis is one of the most common degenerative diseases that attack the joints and cause deformity in the elderly. The purpose of this study was to investigate the link between dhuha prayer and the risk of knee osteoarthritis (kOA). Methods: cross-sectional and purposive sampling, with inclusion criteria including Muslim women cured in the Government Binjai Senior Care, age greater than or equal to 60 years, communicative, signing informed consent, and providing complete answers to the WOMAC questionnaire to assess kOA risk. The interview form was used to count the number of rak'ahs of dhuha prayer that are usually performed every day. SPSS was used to analyze the data, and the Spearman Rank test was used. The research criteria were met by 30 of 101 prospective respondents. The respondents ages range from 60 to 85 years old, 68% are at risk of mild kOA, and there is a link between the number of rak'ahs of dhuha prayer and a lower risk of kOA. Conclusion: The more rak'ahs of dhuha prayer that are performed on a daily basis, the lower the risk of KOA.
PERBANDINGAN EFEKTIVITAS MADU TRIGONA DAN MADU SIDR DIKOMBINASIKAN DENGAN MINYAK JINTAN HITAM (Nigella sativa) SEBAGAI HEPATOPROTEKTOR TIKUS WISTAR (Rattus norvegicus) YANG DIINDUKSI PARASETAMOL AQILAH HANIFA; DES SURYANI
JURNAL ILMIAH KOHESI Vol 7 No 2 (2023): JURNAL ILMIAH KOHESI
Publisher : LP2MTBM MAKARIOZ

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Abstract

Paracetamol is an antipyretic and analgesic that is often used, but the use of excessive doses can cause hepatotoxicity. Black cumin oil and honey have been shown to have benefits for treating various health problems, especially protecting the liver from hepatotoxicity. Sidr honey is a monofloral honey produced by Apis mellifera bees. Trigona honey is a multi floral honey produced by Trigona sp. To compare the effectiveness of black cumin oil plus trigona honey with black cumin oil plus sidr honey on the liver function of rats induced by paracetamol. Experimental research with posttest only with controlled group design. A total of 4 groups were treated for 28 days. SGOT and SGPT levels were tested. Data analysis used one-way ANOVA post hoc Bonferroni. There was an effect of giving a single dose of paracetamol 2 g/kgBW on liver function of rats characterized by increased levels of SGOT and SGPT in the Positive Control group, there was no significant difference in giving black cumin oil at a dose of 2 ml/kgBW plus sidr honey at a dose of 1 g/kgBW and Black cumin oil at a dose of 2 ml/kgBW plus trigona honey at a dose of 7,4 ml/kgBW for 28 days on the liver of rats that had been induced by paracetamol (p>0.05).The administration of toxic doses of paracetamol caused a decrease in the liver function of rats. The combination of black cumin oil with sidr honey and trigona honey has the same hepatoprotective effectiveness. Paracetamol is an antipyretic and analgesic that is often used, but the use of excessive doses can cause hepatotoxicity. Black cumin oil and honey have been shown to have benefits for treating various health problems, especially protecting the liver from hepatotoxicity. Sidr honey is a monofloral honey produced by Apis mellifera bees. Trigona honey is a multi floral honey produced by Trigona sp. To compare the effectiveness of black cumin oil plus trigona honey with black cumin oil plus sidr honey on the liver function of rats induced by paracetamol. Experimental research with posttest only with controlled group design. A total of 4 groups were treated for 28 days. SGOT and SGPT levels were tested. Data analysis used one-way ANOVA post hoc Bonferroni. There was an effect of giving a single dose of paracetamol 2 g/kgBW on liver function of rats characterized by increased levels of SGOT and SGPT in the Positive Control group, there was no significant difference in giving black cumin oil at a dose of 2 ml/kgBW plus sidr honey at a dose of 1 g/kgBW and Black cumin oil at a dose of 2 ml/kgBW plus trigona honey at a dose of 7,4 ml/kgBW for 28 days on the liver of rats that had been induced by paracetamol (p>0.05).The administration of toxic doses of paracetamol caused a decrease in the liver function of rats. The combination of black cumin oil with sidr honey and trigona honey has the same hepatoprotective effectiveness. Keywords: Liver, Sidr honey, Trigona honey, Black cumin oil, Paracetamol, SGOT, SGPT
Pengaruh Protektif Ekstrak Daun Kemangi (Ocimum sanctum) terhadap Fungsi Ginjal Tikus Wistar Jantan yang Diinduksi Aspartam Nurhakiki Zahara Arif; Des Suryani
JURNAL PANDU HUSADA Vol 1, No 3 (2020)
Publisher : Universitas Muhammadiyah Sumatera Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30596/jph.v1i3.4664

Abstract

Aspartam adalah salah satu pemanis buatan yang paling banyak digunakan di dunia. Konsumsi aspartam dapat menyebabkan kerusakan ginjal yang ditandai dengan adanya peningkatan dari kadar ureum dan kreatinin. Daun kemangi sudah lama digunakan sebagi obat. Banyak penelitian yang menunjukkan bahwa ekstrak daun kemangi memiliki efek sebagai antioksidan dan renal protektor namun dosis masih berbeda-beda antar peneliti.Penelitian ini bertujuan untuk menilai manakah dosis ekstrak daun kemangi (Ocimum sanctum) yang paling efektif dan dibandingkan dengan kurkuma (Curcuma xanthorrhiza) terhadap fungsi ginjal tikus Wistar jantan yang di induksi aspartam.Penelitian ini menggunakan metode eksperimental dengan dengan rancanganPost Test Only Control Group Design. Penelitian ini menganalisis data dengan menggunakanOne Way ANOVAdanPost HocLSD.Dengan menggunakan One Way ANOVA, penelitian ini menunjukkan hasil p=0,00 (p0,05) untuk ureum dan nilai p=0,00 (p0,05) untuk kreatinin yang menunjukkan bahwa terdapat perbedaan pada setiap kelompok. Pada ujiPost HocLSD didapatkan p0,05 yang menunjukkan bahwa terdapat perbedaan yang signifikan pada setiap kelompok.Dosis yang paling efektif dari ekstrak daun kemangi adalah 300 mg/kgBB/hari namun dibandingkan dengan kontrol negatif belum tercapai dosis yang diharapkan
Perbandingan Efek Protektif Ekstrak Daun Kemangi (Ocimum sanctum) dan Kurkuma (Curcuma xanthoriza) Terhadap Fungsi Hepar Tikus Wistar jantan yang Diinduksi Aspartam Vici Vitricia Melja; Des Suryani
JURNAL PANDU HUSADA Vol 1, No 3 (2020)
Publisher : Universitas Muhammadiyah Sumatera Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30596/jph.v1i3.4665

Abstract

Latar Belakang: Aspartam merupakan pemanis buatan pengganti sukrosa yang digunakan untuk bahan tambahan makanan, minuman serta obat. Aspartam berpotensi untuk merusak hepar karena dimetabolisme di hepar dan menghasilkan metabolit berupa formaldehid yang dapat merusak sel hepar. Obat herbal yang digunakan sebagai pencegahan gangguan hepar adalah kurkuma. Ekstrak daun kemangi bekerja dengan mengendalikan kerusakan hepatosit yang diakibatkan oleh penggunaan aspartam, menurunkan kadar lipid peroksidase dan meningkatkan kadar antioksidan. Tujuan: Penelitian ini bertujuan untuk mengetahui dan mempelajari pengaruh ekstrak daun kemangi terhadap fungsi hepar tikus jantan galur Wistar yang di induksi aspartam. Metode: Penelitian eksperimental laboratorik dengan posttest only with control group design. Tikus dibagi menjadi 5 kelompok dan diberi perlakuan selama 30 hari. Penelitian ini menganalisis kadar SGOT dan SGPT setiap kelompok perlakuan. Analisis data menggunakan analisa one-way ANOVA post hoc Games-Howell. Hasil: Penelitian ini menunjukkan adanya pengaruh pemberian aspartam pada kerusakan hepar pada tikus yang diberi aspartam dosis 100 mg/KgBB/hari dengan tikus yang diberi aquabides (p0,05). Pemberian ekstrak daun kemangi dosis 200 mg/KgBB dan dosis 300 mg/KgBB bepengaruh terhadap hepar yang telah diinduksi aspartam (p0,05). Kesimpulan: Pemberian aspartam memiliki pengaruh terhadap kerusakan hepar tikus. Adanya perbaikan dari hepar setelah diberikan ekstrak daun kemangi dan kurkuma pada tikus yang diinduksi aspartam.Kata Kunci: Aspartam, ekstrak daun kemangi, hepar, kurkuma, SGOT, SGPT
Perbandingan Efektivitas Madu Trigona Dan Madu Sidr Dikombinasikan Dengan Minyak Jintan Hitam (Nigella Sativa) Sebagai Nefroprotektor Tikus Wistar (Rattus Norvegicus) Yang Diinduksi Parasetamol Shinta Damayanti; Des Suryani
JURNAL PANDU HUSADA Vol 2, No 3 (2021)
Publisher : Universitas Muhammadiyah Sumatera Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30596/jph.v2i3.9402

Abstract

Parasetamol adalah salah satu obat analgetik-antipiretik yang paling umum digunakan di seluruh dunia. Penggunaan dengan dosis toksik dapat menimbulkan kerusakan ginjal. Minyak jintan hitam dan madu digunakan sebagai obat untuk berbagai masalah kesehatan. madu trigona adalah madu multiflora dan madu sidr merupakan madu monoflora yang telah diolah dengan lebih baik dan diimpor dari luar negeri dengan harga yang mahal. membandingkan efektivitas minyak jintan hitam ditambah madu trigona dengan minyak jintan hitam ditambah madu sidr terhadap fungsi ginjal tikus yang diinduksi parasetamol. penelitian eksperimental dengan rancangan posttest only with controlled group design. Sebanyak 4 kelompok diberi perlakuan selama 28 hari. Uji kadar Ureum dan Kreatinin dilakukan. Analisis data menggunakan one way ANOVA post hoc bonferroni. Terdapat pengaruh pemberian parasetamol dosis tunggal 2 g/KgBB pada fungsi ginjal tikus ditandai dengan peningkatan kadar Ureum dan kreatinin pada kelompok KP, tidak terdapat perbedaan signifikan pemberian minyak jintan hitam dosis 2 ml/kgBB ditambah madu sidr dengan dosis 1 g/kgBB dan minyak jintan hitam dosis 2 ml/kgBB ditambah madu trigona dengan dosis 7,4 ml/kgBB selama 28 hari terhadap ginjal tikus yang telah diinduksi parasetamol (p0,05). Pemberian parasetamol memiliki pengaruh terhadap kerusakan ginjal tikus. Serta pemberian minyak jintan hitam ditambah madu dibandingkan dengan minyak jintan hitam ditambah madu trigona memiliki efek nefroprotektor yang sama.
Co-Authors Aidil Akbar Ance Roslina AQILAH HANIFA Balemun Kaisar Harahap Cindy Mentari Debby Mirani Lubis DEDY DWI PUTRA Ecie Budiyanti Eka Airlangga ELMAN BOY Fadhila, Mutia Fadhilla Qudsi Ramadhani Fadhilla Qudsi Ramadhani Fatimah Zahra Febriyanti, Eka Fujiati, Isti Ilmiati HANNY RAHMI LUBIS Hidayati, Nurul Hildaini Fatma Tanjung Humairah Medina Liza Lubis Ika Nopa IKHFANA SYAFINA Jeanne Adiwinata Pawitan KARTIKA HANDAYANI Khairunnisa Ariqah Sihombing MAULIDA SHAFI Muhammad Edy Syahputra Nasution Muhammad Iqbal Muhammad Jalaluddin Assuyuthi Chalil Mutia Fadhilla Nathasya Putri Kinanti Nuralita, Nanda Sari Nurfadhilah Amini Nasution Nurhakiki Zahara Arif Nurhasanah Nurhasanah Octari Auliati Pertiwi, Retno Ratih Yulistika Utami Ritonga, Annisa Qarunia RIZKY NURDIANTY Septi Dwi Pratiwi Shinta Damayanti Siregar, Pinta Pudiyanti Siti Mirhalina Hasibuan Vici Vitricia Melja WIDYA AFIFAH Yulia Afriani Nasution Zakiya Rafwiani