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All Journal Open Access Health Scientific Journal Riset Informasi Kesehatan Media Penelitian dan Pengembangan Kesehatan Strada Journal of Pharmacy
Devientasari, Chinthia
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Biochemistry, Genetics & Molecular Biology Chemistry Decision Sciences, Operations Research & Management Dentistry Environmental Science Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Public Health Veterinary

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Association of medication adherence with clinical outcomes and quality of life in type 2 diabetes mellitus patients: a cross-sectional study Fandinata, Selly Septi; Putra, Deddy Aryanda; Lubada, Eziah Ika; Sari, Silfiana Nisa Permata; Devientasari, Chinthia; Ernawati, Iin; Suryandari, Mercyska; Berliana, Dini
Media Penelitian dan Pengembangan Kesehatan Vol. 36 No. 1 (2026): MEDIA PENELITIAN DAN PENGEMBANGAN KESEHATAN
Publisher : Poltekkes Kemenkes Bandung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.34011/jmp2k.v36i1.2218

Abstract

Background: Type 2 diabetes mellitus is a chronic metabolic disorder characterized by elevated blood glucose levels. Patient adherence to medication is a critical factor in effective management, as it can reduce morbidity and mortality while improving health-related quality of life (HRQoL). Digital interventions, such as smartphone-based medication reminder applications, represent a promising strategy to enhance adherence. Objective: This study aimed to examine the relationship between medication adherence and clinical outcomes, specifically fasting blood glucose levels and HRQoL, among patients with type 2 diabetes in primary health care settings. Methods: A cross-sectional pre–post test design was employed involving 96 respondents, divided equally into control and intervention groups, selected through convenience sampling. Primary data were collected using the MARS-10 adherence questionnaire and the DQOL Brief Clinical Inventory, while secondary data were obtained from pre– and post–fasting blood glucose measurements. Results: Results showed no significant relationship between medication adherence and fasting blood glucose levels (p > 0.05), nor between adherence and HRQoL (p > 0.05), even with the implementation of the Drug Reminder App intervention. Conclusion: These findings highlight the need for additional interventions or further innovations in digital adherence support to improve clinical and quality-of-life outcomes in type 2 diabetes management.
Analysis of the Relationship Between HIV/AIDS Clinical Stage and Opportunistic Infections at Hospital X Devientasari, Chinthia; Selly Septi Fandinata
Strada Journal of Pharmacy Vol. 8 No. 1 (2026): April
Publisher : Universitas STRADA Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30994/sjp.v8i1.287

Abstract

Opportunistic infections remain a major cause of morbidity and mortality among people living with Human Immunodeficiency Virus (HIV). The progressive decline in immune function increases susceptibility to infections such as tuberculosis, candidiasis, and toxoplasmosis. The World Health Organization (WHO) clinical staging system is widely used to assess HIV disease progression and is often associated with the occurrence of opportunistic infections. This study aimed to analyze the association between HIV clinical stage and opportunistic infections among HIV/AIDS patients at Hospital X. This study employed an observational analytic design with a cross-sectional approach. Data were obtained from medical records of HIV/AIDS patients, with a total sample of 193 patients selected using total sampling. Statistical analyses included univariate and bivariate analyses using the chi-square test. The majority of patients were in clinical stage III (80.3%). The prevalence of opportunistic infections was 14.0%. The results of the chi-square test showed no significant association between clinical stage and opportunistic infections (p = 0.206). Although opportunistic infections were more frequently observed in advanced stages, the relationship was not statistically significant.
Co-Authors Abdul Rohim, Abdul Adi Wibisono Anggra I.N.A Berliana, Dini Dandi Fathor Rozy Pradana Saputra Ernawati, Iin Eziah Ika Lubada Fidi Setyawan Gading Nurantika Hanie Kusuma Wardani Hanik Maria Dewi Mercyska Suryandari Putra, Deddy Aryanda Putri, Luluk Aniqoh Meliana Resca S.S. Sari, Silfiana Nisa Permata Septi Fandinata, Selly Titis Surya A