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All Journal Journal of Research and Technology JURNAL EDUCATION AND DEVELOPMENT Journal of Herbal, Clinical and Pharmaceutical Science (HERCLIPS) Community Development Journal: Jurnal Pengabdian Masyarakat Journal of Pharmaceutical Care Anwar Medika Journal Pharmasci (Journal of Pharmacy and Science) International Journal of Islamic and Complementary Medicine Farmasis: Jurnal Sains Farmasi Jurnal Abdi Masyarakat Kita NUSANTARA: Jurnal Pengabdian Kepada Masyarakat SITAWA : Jurnal Farmasi Sains dan Obat Tradisional GEMBIRA (Pengabdian Kepada Masyarakat) Jurnal Komunitas Farmasi Nasional
Mercyska Suryandari
Akademi Farmasi Surabaya
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Aktivitas Antibakteri Daun Pepaya (Carica Pepaya) Menggunakan Pelarut Etanol Terhadap Bakteri Escherichia Coli Sudarwati, Tri Puji Lestari; Suryandari, Mercyska
Journal of Pharmaceutical Care Anwar Medika (J-PhAM) Vol 1 No 2 (2019): Volume 1, Nomor 2, Juni 2019
Publisher : STIKES Rumah Sakit Anwar Medika

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36932/jpcam.v1i2.11

Abstract

Isolasi zat aktif dari herba menimbulkan pandangan baru bahwa tiap herba memiliki zat aktif (satu atau lebih). Carica papaya L memiliki zat aktif yang berhasil diisolasi, zat – zat tersebut dapat menggantikan pemakaian herba untuk tujuan pengobatan. Escherichia coli merupakan bakteri yang banyak terdapat di usus besar (colon) manusia dan sebagai flora normal colon, sifat Escherichia coli dapat menyebabkan infeksi primer pada usus besar sehingga menyebabkan penyakit diare. Sampel yang digunakan adalah Daun Pepaya tua berwarna hijau tua yang diperoleh dari UPT Materia Medika Batu. Dicuci bersih kemudian dikeringkan, kemudian dihaluskan dengan cara diblender. Proses ekstraksi menggunakan metode maserasi. Pengujian dilakukan dengan menggunakan 5 konsentrasi dan kontrol negatif. Metode pengujian antibakteri yang digunakan adalah difusi kertas cakram. Diameter zona hambat pada tiap konsentrasi dianalisis menggunakan statistik menggunakan uji ANOVA. Berdasarkan hasil pengujian dengan melakukan replikasi sebanyak 6 kali pada konsentrasi 20 µ g/mL dengan rata – rata 7,25 mm, 40 µ g/mL dengan rata – rata 7,43 mm, 60µ g/mL dengan rata – rata 7,7 mm, 80 µ g/mL dengan rata – rata 7,8 dan 100 µ g/mL dengan rata – rata 7,9 mm dengan kategori sedang. Dapat dikatakan terdapat pengaruh aktivitas antibakteri pada Daun Pepaya (Carica papaya L) dengan bakteri Escherichia coli maka, semakin tinggi konsentrasi maka daya hambat yang dihasilkan semakin tinggi.
Profil Peresepan Penyakit Mata Glaukoma pada Pasien BPJS Rawat Jalan (Studi dilaksanakan di RS Mata Masyarakat JawaTimur Periode Januari - Desember 2015) Mustofa, Achmad; Ulfa, Ninik Mas; Suryandari, Mercyska
Journal of Pharmacy and Science Vol. 1 No. 1 (2016): Journal of Pharmacy and Science
Publisher : Akademi Farmasi Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53342/pharmasci.v1i1.57

Abstract

ABSTRAKGlaukoma adalah penyakit kerusakan saraf optik mata, penyebabnya adalah tingginya tekanan bola mata, diatas 20mmHG. Rata-rata penderita glaukoma adalah glaukoma primer sudut terbuka (POAG) danglaukoma primer sudut tertutup (PACG). Di Rumah Sakit Mata Masyarakat (RSMM) JawaT imur, glaukoma menempati urutan ketiga dalam daftar 10 penyakit terbanyak. Sehingga dilakukan penelitian profil peresepan penyakit mataglaukoma pada pasien BPJS rawat jalan di RSMM Jatim periode Januari- Desember 2015.Penelitian ini bersifat observasional, pengambilan data bersifat retrospektif, penyajian data secara deskriptif. Observasi dengan mengumpulkan resep dokter mata, mencatat usia, golongan obat, nama generik, bentuk sediaan, prosentase obat glaukoma POAG dan glaukoma PACG. Hasil inklusi 2050 resepdan 1461 pasien glaukoma, terdapat 420 pasienglaukoma POAG, 190 pasien glaukoma PACG, dan 851 pasien glaukoma yang lain. Pasien terbanyak usia 61-80 tahun (52,50%), terendah usia ≥81 tahun sebanyak 49 pasien (3,35%). Bentuk sediaan terbanyak, yaitu tetes mata sebanyak 3766 (69,01%). Penggolongan obat terbanyak adalah penyekat β non selektif yaitu Timolol 1783 (32,67%), terendah golongan prostaglandin analog yaitu Travoprost 35 (0,64%). Pada glaukoma POAG, golongan terbanyak adalah golongan penyekat β non selektif yaitu Timolol 203 (29,29%), terendah adalah prostaglandin analog yaitu Latanoprost 83 (11,98%). Pada glaukoma PACG, terbanyak adalah penyekat β yaitu Timolol 81 (29,03%), terendah adalah golongan agonis kolinergik yaitu Pilokarpin 26 (9,32%). Pada penelitian ini disarankan agar dilakukan penelitian lebih lanjut tentang efektifitas peresepan penyakit mata glaukoma di RSMM Jatim.Kata kunci : peresepan glaukoma, glaukoma primer sudut terbuka, glaukoma primer sudut tertutup, klasifikasi obat.ABSTRACTGlaucoma is an eye disease that causes damages to the optic nerve, because high intraocular pressure, above 20mmHg.Glaucoma ranks third in the list of ten most diseases in RSMM. It is important to study the prescription profile of BPJS glaucoma patient in outpatient Eye Hospital in East Java Community period from January to December 2015. The inclusion in 2050 of a prescription, there are 1461 glaucoma patients. 420 with open-angle glaucoma(POAG), 120 patients with close-angle glaucoma (PACG), and 851 patients with others glaucoma. Based on the patient’s age, most patients aged 61-80 years (52.50%), lowest age of ≥81 years in 49 patients (3.35%). Based on the modest dosage forms, namely eye drops as much as 3766 (69.01%). Based on theclassification of drugs, most were non-selective β-blockers ie Timolol 1783 (32.67%), the least class of prostaglandin analogues were Travoprost 35 (0.64%). In POAG, the modest group was non-selective β-blockers ie Timolol 203 (29.29%), carbonic anhydrase inhibitors group, ie Acetazolamide 181 (26.12%), prostaglandin analogues group ie Latanoprost 83 (11.98%). In PACG the modest group was β-blockers, ie Timolol 81 (29.03%), carbonic anhydrase inhibitors group ie Acetazolamide 70 (25.09%), cholinergic agonist group ie Pilocarpine 26 (9.32%). In this study’s suggested that further research on the effectiveness of the prescription of eye disease glaucoma in Community Eye Hospital East Java.Keywords: Glaucoma prescription, primary open angle glaucoma, primary angle-closure glaucoma, drug classification
Validasi Metode Analisis Formaldehid Pada Tisu Basah Wahyuniati, Dwi; Yulianti, Cicik Herlina; Suryandari, Mercyska
Journal of Pharmacy and Science Vol. 3 No. 2 (2018): Journal of Pharmacy and Science
Publisher : Akademi Farmasi Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53342/pharmasci.v3i2.117

Abstract

ABSTRAKTisu basah merupakan istilah umum untuk menggambarkan sepotong bahan, umumnya ditambahkan dengan komposisi cairan atau semi cair, dimaksudkan untuk membersihkan dan memberikan rasa lembut. Tisu basah memiliki struktur berserat terdiri dari campuran serat selulosa pulp dan regenerasi, seperti rayon dan atau liosel, dengan atau tanpa serat pengikat. Pada proses produksi, komponen-komponen yang sengaja ditambahkan pada pembuatan tisu basah salah satunya adalah formaldehid sebagai penguat keadaan basah. Akan tetapi penggunaan yang berlebihan dapat menyebabkan ruam pada kulit (dermatitis). Pada penelitian ini dilakukan validasi metode analisis formaldehid pada tisu basah dengan menggunakan metode absorpsi uap SNI ISO 14184-2:2015 dengan pereaksi nash menggunakan spektrofotometri UV-Vis. Sampel yang digunakan adalah tisu basah dari satu merek. Validasi metode dilakukan untuk memastikan metode SNI ISO 14184-2:2015 dapat diterapkan, diperoleh hasil valid, dengan nilai R = 0,9993, yang mendekati nilai 1, menghasilkan persamaan regresi linier y = 0,0294x - 0,0317. Pengujian akurasi diperoleh rata-rata persen recovery sebesar 84,54%, 102,05%, dan 106,13%. Nilai RSD sebesar 1,62%. Hasil nilai LOD sebesar 0,040, sedangkan hasil nilai LOQ sebesar 0,136. Hasil validasi terhadap metode SNI ISO 14184 – 2 : 2015 dapat disimpulkan bahwa metode SNI ISO 14184-2:2015 dapat digunakan untuk menguji formaldehid pada tisu basah. Kata kunci: Validasi, Tisu basah, Formaldehid, Pereaksi Nash, Spektrofotometri UV-Vis.ABSTRACT Wet wipes are the general terms to describe a piece of material, generally impregnated with a liquid or semi liquid composition, intended to both cleaning and providing a smooth feeling. Wet wipes has fibrous structures consist of a mixture of pulp and regenerated cellulose fibers, such as rayon and/or lyocell, with or without binding fibers. In product process, one of components expressly added was formaldehyde as strengthener as wet condition. But, excessive use of formaldehyde can cause skin rash (dermatitis). This study was aimed to Analysis Method Validation of Formaldehyde of Wet Wipes used vapour absorption SNI ISO 14184-2:2015 method with Nash Reagents by UV-Vis Spectrophotometry, and used vapour absorption method. The wet wipes sample used was from one brand. Method validation was conducted to definite SNI ISO 14184-2:2015 method can be applied, the result was valid, r value is 0,9993, the linear regression y = 0,0294x – 0,0317, accuracy percent recovery study showed 84,54%, 102,05%, and 106,13%., Related standar deviation showed 1,62%, limit of detection was 0,040, limit of quantitation was 0,136. The validation result of SNI ISO 14184-2:2015 method can be concluded that SNI ISO 14184-2:2015 method can be applied to examine formaldehid on wet wipes.Keywords: Wet wipes, Formaldehyde, Validation, Nash Reagent, UV-Vis Spectrophotometry.
PENINGKATAN PENGETAHUAN MASYARAKAT MENGENAI PERKEMBANGAN DAN PENYEBARAN DBD Tri Puji Lestari Sudarwati; M.A Hanny Ferry Fernanda; Mercyska Suryandari
Jurnal Abdi Masyarakat Kita Vol 1 No 1 (2021): Jurnal Abdi Masyarakat Kita
Publisher : APDFI (Asosiasi Pendidikan Diploma Farmasi Indonesia)

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (1176.178 KB) | DOI: 10.33759/asta.v1i1.92

Abstract

This community service event was aimed to elevate the knowledge of local society regarding the current update of Aedes aegypti mosquito as a vector of Dengue Hemorrhagic Fever (DHF). Hence, it raised awareness of their role in breaking the disease transmission. Involving students as supporting team, this activity was carried out at Jemur Gayungan RW 01 by giving public counselling and mentoring for the larvae surveyor cadre (Jumantik). Abdimas, which has been done, adds to the knowledge of jumantik cadres about the proliferation and spread of dengue, so that jumantik cadres not only observe their environment but can also take action to break the chain of dengue spread.
SOSIALISASI PEMILIHAN PERALATAN MAKAN DAN MINUM BERBAHAN MELAMIN YANG AMAN DI POSYANDU LANSIA KETINTANG SURABAYA Surahmaida Surahmaida; Mercyska Suryandari; Meyke Herina Syafitri; Ninik Mas Ulfa
Community Development Journal : Jurnal Pengabdian Masyarakat Vol. 3 No. 3 (2022): Volume 3 Nomor 3 Tahun 2022
Publisher : Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/cdj.v3i3.9424

Abstract

Peralatan makan dan minum dari melamin banyak digunakan di berbagai kalangan masyarakat karena tidak mudah pecah, awet, harganya terjangkau dan umumnya memiliki desain dengan warna dan motif yang menarik. Namun, peralatan makan minum bermelamin dianggap berpotensi membahayakan kesehatan. Hal ini dikarenakan masyarakat cenderung memilih peralatan makan minum yang harganya murah tanpa memperhatikan label keamanan produk dan perawatan penggunaan produk. Adanya kegiatan Pengabdian pada Masyarakat ini bertujuan untuk memberikan pengetahuan kepada masyarakat mengenai pengertian melamin, keunggulan produk peralatan makan dan minum bermelamin, bahaya melamin bagi tubuh, pentingnya membaca kode produk dan tips aman penggunaan peralatan makan bermelamin. Hasil dari kegiatan pengabdian masyarakat ini agar masyarakat memahami dan mulai menerapkan budaya teliti sebelum membeli dan menggunakan produk peralatan makan dan minum dari bahan melamin yang benar sebagai upaya menjaga kesehatan keluarga.
Identification of Secondary Metabolites of Onion Peels Extract (Allium cepa L.) of Various Solvent: Identifikasi Senyawa metabolit Sekunder Ekstrak Kulit Bawang Merah (Allium cepa L.) dari Berbagai Macam Pelarut Mercyska Suryandari; Galuh Gondo Kusumo
Journal Pharmasci (Journal of Pharmacy and Science) Vol. 7 No. 2 (2022): Journal Pharmasci (Journal of Pharmacy and Science)
Publisher : Akademi Farmasi Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53342/pharmasci.v7i2.289

Abstract

Onion peels (Allium cepa L.) is often disposed of without being used and ends up as waste in markets that can pollute the environment. Onion peels can potentially be developed for treatment as an anti-cancer because of its phytochemical compounds. Previous studies have shown that secondary metabolites found in onion peels using different solvents produce different secondary metabolites. So the purpose of this study was to find out the secondary metabolite compounds from onion peels extract (Allium cepa L.) qualitatively when extracted using 5 different solvents. This research was conducted using a phytochemical screening method on the onion peels extract (Allium cepa L.). n-Hexane, Ethyl Acetate, Acetone, Ethanol 96%, and Chloroform were used in the maceration extraction method separately. The results showed that the yield value was 0.96%; 2.66%; 3.90%; 4.80%; 1.62%. The results showed that acetone, ethanol, and chloroform extracts of onion peels extract (Allium cepa L.) contained alkaloids, flavonoids, saponins, steroids, terpenoids, and tannins. Meanwhile, the ethyl acetate extract of onion peels contains alkaloids, flavonoids, steroids, terpenoids, and tannins. Lastly, the n-hexane extract of the onion peels only contains steroids and terpenoids. So it can be concluded that secondary metabolites in onion peels extract contain alkaloids, flavonoids, saponins, steroids, terpenoids, and tannins.
Pengaruh Pengeringan Terhadap Senyawa Fitokimia Simplisia dan Kadar Flavonoid Total Ekstrak Etanol Buah Cabe Jawa Meyke Herina Syafitri; Mercyska Suryandari; Jezzita Aureola Martha
Journal of Herbal, Clinical and Pharmaceutical Science (HERCLIPS) Vol 4 No 02 (2023): HERCLIPS VOL 04 NO 02
Publisher : Universitas Muhammadiyah Gresik

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30587/herclips.v4i02.5304

Abstract

Cabe jawa (Piper retrofractum Vahl.) banyak digunakan oleh masyarakat sebagai bumbu dan obat tradisional. Petani di Madura biasanya akan merebus buah ini sebelum menjemurnya di bawah sinar matahari langsung untuk mempersingkat waktu pengeringan. Namun belum ada studi yang mempelajari apakah proses seperti ini dapat mempengaruhi kandungan simplisia yang dihasilkan. Untuk mengetahuinya, penelitian kali ini dilakukan dengan menggunakan sampel buah cabe jawa berwarna merah yang dikeringkan menggunakan 2 metode, yaitu dengan cara kering-angin (Metode I), sedangkan yang kedua dengan direbus terlebih dahulu selama beberapa menit kemudian dijemur di bawah sinar matahari langsung (Metode II). Sebagian serbuk simplisia kering yang dihasilkan dari kedua kelompok diidentifikasi kandungannya melalui skrining fitokimia. Hasilnya, kedua kelompok sama-sama mengandung alkaloid, flavonoid, terpenoid, steroid, tanin dan saponin. Selanjutnya, sisa serbuk dari masing-masing kelompok diekstraksi dengan etanol. Ekstrak kental yang dihasilkan kemudian ditetapkan kadar flavonoid totalnya menggunakan spektrofotometer UV-Vis dengan kuersetin sebagai pembanding. Kadar flavonoid total yang diperoleh yakni sebesar 42,88 dan 47,83 mg QE/g ekstrak masing-masing untuk metode I dan II. Penelitian ini menunjukkan bahwa secara kualitatif tidak terdapat perbedaan kandungan senyawa fitokimia, namun secara kuantitatif terdapat perbedaan signifikan terhadap kandungan flavonoid total dari kedua kelompok perlakuan.
Antioxidan Activity from Methanol Extract of Kratom Leaves (Mitragyna speciosa) Maseration Result Using The DPPH Method: Aktivitas Antioksidan Ekstrak Metanol Daun Kratom (Mitragyna speciosa) Hasil Maserasi Menggunakan Metode DPPH Andhika Dwi Aristyawan; Anggi Ayu Windari; Mercyska Suryandari; Galuh Gondo Kusumo
Journal Pharmasci (Journal of Pharmacy and Science) Vol. 8 No. 2 (2023): Journal Pharmasci (Journal of Pharmacy and Science)
Publisher : Akademi Farmasi Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53342/pharmasci.v8i2.357

Abstract

Antioxidants are compounds that can prevent the formation of free radicals. Kratom is a typical plant from South Putussibau area, in West Kalimantan. The kratom plant contains alkaloids, triterpenoid-steroids, saponins, tannins and flavonoids. The main component of kratom leaves is an indole alkaloid that is efficacious as an antioxidant. The goal is to determine the antioxidant activity of kratom leaf extract (Mitragyna speciosa). The method used is the measurement of the reduced amount of DPPH from an antioxidant compound UV-Vis spectrophotometrically at a wavelength of 517nm using Vitamin C as a comparison. The extraction method used is maceration. The test was sampled 10 mg of kratom leaf extract (Mitragyna speciosa) with 10 ppm, 20 ppm, 30 ppm, 40 ppm, and 50ppm concentrations, then repeated 3 times. The results of the antioxidant activity of kratom leaves (Mitragyna speciosa) were expressed with IC50 values of 44,169 ± 0.5313 with an RSD value of 1.202%. Then it can be concluded that kratom leaf methanol extract (Mitragyna speciosa) has a very strong antioxidant activity with an IC50 value of 44,169 ± 0.5313 with an RSD value of 1.202%.
SKRINING FITOKIMIA EKSTRAK ETANOL 80% ROSEMARY (Rosmarinus officinalis L.) DENGAN METODE EKSTRAKSI DIGESTI Evi Priyatno; Mercyska Suryandari
Jurnal Komunitas Farmasi Nasional Vol. 2 No. 1 (2022): Jurnal Komunitas Farmasi Nasional
Publisher : Akademi Farmasi Yarsi Pontianak

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Rosemary (Rosmarinus officinalis L.) in the Lamiacea family is one of the herbal plants that has medicinal properties. Based on its potential benefits, a phytochemical screening study was conducted to determine the class of secondary metabolites contained in it and to test the ability of 80% ethanol for extracting secondary metabolites from rosemary extract using the digestion extraction method. The filtrate was then concentrated using a rotary evaporator and phytochemical screening tests were carried out by observing the presence of color changes, formation of precipitates, and the formation of stable foam using certain reagents. The results showed that the ethanol extract of 80% rosemary was positive for terpenoids, alkaloids, flavonoids, saponins, tannins, and polyphenols
Identification of Secondary Metabolites of Garlic Peels Extract (Allium sativum) Mercyska Suryandari Mercyska; Galuh Gondo Kusumo; Ade Ferdinan
Jurnal Komunitas Farmasi Nasional Vol. 2 No. 2 (2022): Jurnal Komunitas Farmasi Nasional
Publisher : Akademi Farmasi Yarsi Pontianak

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

The use of garlic often only makes use of the root part, while the garlic skin is often thrown away without optimal utilization and ends up as waste. Garlic skin has the potential to be developed as a treatment, one of which is for cholesterol because it contains phytochemical compounds. Previous studies have shown that using different solvents during the extraction process will produce different secondary metabolites. So the purpose of this study was to find out the secondary metabolites of garlic skin extract (Allium sativum L.) qualitatively when extracted using 5 different solvents. In this research, the method used was phytochemical screening on garlic skin extract (Allium sativun L.). n-Hexane, Ethyl Acetate, Acetone, 96% Ethanol, and Chloroform using remaceration extraction method separately. The results showed that the yield value was 0.90%; 1.34%; 1.00%; 3.90%; 1.20%. The results showed that the n-Hexane extract of garlic (Allium sativum L.) peels contained steroids and terpenoids; ethyl acetate extract contains alkaloids, steroids and terpenoids; acetone extract contains saponins, steroids, terpenoids and tannins; 96% ethanol extract contains alkaloids, flavonoids, saponins, terpenoids, and tannins; and finally the chloroform extract of garlic skin contains alkaloids, steroids, terpenoids and tannins. So it can be concluded that the secondary metabolites in garlic peel extract contain alkaloids, flavonoids, saponins, steroids, terpenoids and tannins.the study, methods, results and conclusions, can describe qualitatiive and quantitative information.
Co-Authors Ade Ferdinan Alfiana, Silvina Sita Andik Isdianto Anggi Ayu Windari Ari Anggraini, Nony Aristyawan, Andhika Dwi Avanti, Christina Cicik Herlina Yulianti Dwi Rahayu, Risma Evi Priyatno Eziah Ika Lubada Fernanda, M.A. Hanny Ferry Fitrianti, Novariza Galuh Gondo Kusumo Hatidja, Siti Annurijati Jezzita Aureola Martha M.A Hanny Ferry Fernanda M.A. Hanny Ferry Fernanda Meyke Herina Syafitri Mustofa, Achmad Ngurah Rio Juliana, I Made Nur Indahwati, Sephia Rizky Darmawan Septi Fandinata, Selly Sudarwati, Tri Puji Lestari Surahmaida, Surahmaida Syafika Rani, Noor Tri Puji Lestari Sudarwati Ulfa, Ninik Mas Wahyuniati, Dwi Wefa, Ali Yuliarni, Floreta Fiska