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All Journal Journal of Research and Technology JURNAL EDUCATION AND DEVELOPMENT Journal of Herbal, Clinical and Pharmaceutical Science (HERCLIPS) Community Development Journal: Jurnal Pengabdian Masyarakat Journal of Pharmaceutical Care Anwar Medika Journal Pharmasci (Journal of Pharmacy and Science) International Journal of Islamic and Complementary Medicine Farmasis: Jurnal Sains Farmasi Jurnal Abdi Masyarakat Kita NUSANTARA: Jurnal Pengabdian Kepada Masyarakat GEMBIRA (Pengabdian Kepada Masyarakat) Jurnal Komunitas Farmasi Nasional Media Penelitian dan Pengembangan Kesehatan
Mercyska Suryandari
Akademi Farmasi Surabaya
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Aktivitas Antibakteri Daun Pepaya (Carica Pepaya) Menggunakan Pelarut Etanol Terhadap Bakteri Escherichia Coli Sudarwati, Tri Puji Lestari; Suryandari, Mercyska
Journal of Pharmaceutical Care Anwar Medika (J-PhAM) Vol 1 No 2 (2019): Volume 1, Nomor 2, Juni 2019
Publisher : STIKES Rumah Sakit Anwar Medika

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36932/jpcam.v1i2.11

Abstract

Isolasi zat aktif dari herba menimbulkan pandangan baru bahwa tiap herba memiliki zat aktif (satu atau lebih). Carica papaya L memiliki zat aktif yang berhasil diisolasi, zat – zat tersebut dapat menggantikan pemakaian herba untuk tujuan pengobatan. Escherichia coli merupakan bakteri yang banyak terdapat di usus besar (colon) manusia dan sebagai flora normal colon, sifat Escherichia coli dapat menyebabkan infeksi primer pada usus besar sehingga menyebabkan penyakit diare. Sampel yang digunakan adalah Daun Pepaya tua berwarna hijau tua yang diperoleh dari UPT Materia Medika Batu. Dicuci bersih kemudian dikeringkan, kemudian dihaluskan dengan cara diblender. Proses ekstraksi menggunakan metode maserasi. Pengujian dilakukan dengan menggunakan 5 konsentrasi dan kontrol negatif. Metode pengujian antibakteri yang digunakan adalah difusi kertas cakram. Diameter zona hambat pada tiap konsentrasi dianalisis menggunakan statistik menggunakan uji ANOVA. Berdasarkan hasil pengujian dengan melakukan replikasi sebanyak 6 kali pada konsentrasi 20 µ g/mL dengan rata – rata 7,25 mm, 40 µ g/mL dengan rata – rata 7,43 mm, 60µ g/mL dengan rata – rata 7,7 mm, 80 µ g/mL dengan rata – rata 7,8 dan 100 µ g/mL dengan rata – rata 7,9 mm dengan kategori sedang. Dapat dikatakan terdapat pengaruh aktivitas antibakteri pada Daun Pepaya (Carica papaya L) dengan bakteri Escherichia coli maka, semakin tinggi konsentrasi maka daya hambat yang dihasilkan semakin tinggi.
PENINGKATAN PENGETAHUAN MASYARAKAT MENGENAI PERKEMBANGAN DAN PENYEBARAN DBD Tri Puji Lestari Sudarwati; M.A Hanny Ferry Fernanda; Mercyska Suryandari
Jurnal Abdi Masyarakat Kita Vol 1 No 1 (2021): Jurnal Abdi Masyarakat Kita
Publisher : APDFI (Asosiasi Pendidikan Diploma Farmasi Indonesia)

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (1176.178 KB) | DOI: 10.33759/asta.v1i1.92

Abstract

This community service event was aimed to elevate the knowledge of local society regarding the current update of Aedes aegypti mosquito as a vector of Dengue Hemorrhagic Fever (DHF). Hence, it raised awareness of their role in breaking the disease transmission. Involving students as supporting team, this activity was carried out at Jemur Gayungan RW 01 by giving public counselling and mentoring for the larvae surveyor cadre (Jumantik). Abdimas, which has been done, adds to the knowledge of jumantik cadres about the proliferation and spread of dengue, so that jumantik cadres not only observe their environment but can also take action to break the chain of dengue spread.
SOSIALISASI PEMILIHAN PERALATAN MAKAN DAN MINUM BERBAHAN MELAMIN YANG AMAN DI POSYANDU LANSIA KETINTANG SURABAYA Surahmaida Surahmaida; Mercyska Suryandari; Meyke Herina Syafitri; Ninik Mas Ulfa
Community Development Journal : Jurnal Pengabdian Masyarakat Vol. 3 No. 3 (2022): Volume 3 Nomor 3 Tahun 2022
Publisher : Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/cdj.v3i3.9424

Abstract

Peralatan makan dan minum dari melamin banyak digunakan di berbagai kalangan masyarakat karena tidak mudah pecah, awet, harganya terjangkau dan umumnya memiliki desain dengan warna dan motif yang menarik. Namun, peralatan makan minum bermelamin dianggap berpotensi membahayakan kesehatan. Hal ini dikarenakan masyarakat cenderung memilih peralatan makan minum yang harganya murah tanpa memperhatikan label keamanan produk dan perawatan penggunaan produk. Adanya kegiatan Pengabdian pada Masyarakat ini bertujuan untuk memberikan pengetahuan kepada masyarakat mengenai pengertian melamin, keunggulan produk peralatan makan dan minum bermelamin, bahaya melamin bagi tubuh, pentingnya membaca kode produk dan tips aman penggunaan peralatan makan bermelamin. Hasil dari kegiatan pengabdian masyarakat ini agar masyarakat memahami dan mulai menerapkan budaya teliti sebelum membeli dan menggunakan produk peralatan makan dan minum dari bahan melamin yang benar sebagai upaya menjaga kesehatan keluarga.
Identification of Secondary Metabolites of Onion Peels Extract (Allium cepa L.) of Various Solvent: Identifikasi Senyawa metabolit Sekunder Ekstrak Kulit Bawang Merah (Allium cepa L.) dari Berbagai Macam Pelarut Mercyska Suryandari; Galuh Gondo Kusumo
Journal Pharmasci (Journal of Pharmacy and Science) Vol. 7 No. 2 (2022): Journal Pharmasci (Journal of Pharmacy and Science)
Publisher : Akademi Farmasi Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53342/pharmasci.v7i2.289

Abstract

Onion peels (Allium cepa L.) is often disposed of without being used and ends up as waste in markets that can pollute the environment. Onion peels can potentially be developed for treatment as an anti-cancer because of its phytochemical compounds. Previous studies have shown that secondary metabolites found in onion peels using different solvents produce different secondary metabolites. So the purpose of this study was to find out the secondary metabolite compounds from onion peels extract (Allium cepa L.) qualitatively when extracted using 5 different solvents. This research was conducted using a phytochemical screening method on the onion peels extract (Allium cepa L.). n-Hexane, Ethyl Acetate, Acetone, Ethanol 96%, and Chloroform were used in the maceration extraction method separately. The results showed that the yield value was 0.96%; 2.66%; 3.90%; 4.80%; 1.62%. The results showed that acetone, ethanol, and chloroform extracts of onion peels extract (Allium cepa L.) contained alkaloids, flavonoids, saponins, steroids, terpenoids, and tannins. Meanwhile, the ethyl acetate extract of onion peels contains alkaloids, flavonoids, steroids, terpenoids, and tannins. Lastly, the n-hexane extract of the onion peels only contains steroids and terpenoids. So it can be concluded that secondary metabolites in onion peels extract contain alkaloids, flavonoids, saponins, steroids, terpenoids, and tannins.
Pengaruh Pengeringan Terhadap Senyawa Fitokimia Simplisia dan Kadar Flavonoid Total Ekstrak Etanol Buah Cabe Jawa Meyke Herina Syafitri; Mercyska Suryandari; Jezzita Aureola Martha
Journal of Herbal, Clinical and Pharmaceutical Science (HERCLIPS) Vol 4 No 02 (2023): HERCLIPS VOL 04 NO 02
Publisher : Universitas Muhammadiyah Gresik

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30587/herclips.v4i02.5304

Abstract

Cabe jawa (Piper retrofractum Vahl.) banyak digunakan oleh masyarakat sebagai bumbu dan obat tradisional. Petani di Madura biasanya akan merebus buah ini sebelum menjemurnya di bawah sinar matahari langsung untuk mempersingkat waktu pengeringan. Namun belum ada studi yang mempelajari apakah proses seperti ini dapat mempengaruhi kandungan simplisia yang dihasilkan. Untuk mengetahuinya, penelitian kali ini dilakukan dengan menggunakan sampel buah cabe jawa berwarna merah yang dikeringkan menggunakan 2 metode, yaitu dengan cara kering-angin (Metode I), sedangkan yang kedua dengan direbus terlebih dahulu selama beberapa menit kemudian dijemur di bawah sinar matahari langsung (Metode II). Sebagian serbuk simplisia kering yang dihasilkan dari kedua kelompok diidentifikasi kandungannya melalui skrining fitokimia. Hasilnya, kedua kelompok sama-sama mengandung alkaloid, flavonoid, terpenoid, steroid, tanin dan saponin. Selanjutnya, sisa serbuk dari masing-masing kelompok diekstraksi dengan etanol. Ekstrak kental yang dihasilkan kemudian ditetapkan kadar flavonoid totalnya menggunakan spektrofotometer UV-Vis dengan kuersetin sebagai pembanding. Kadar flavonoid total yang diperoleh yakni sebesar 42,88 dan 47,83 mg QE/g ekstrak masing-masing untuk metode I dan II. Penelitian ini menunjukkan bahwa secara kualitatif tidak terdapat perbedaan kandungan senyawa fitokimia, namun secara kuantitatif terdapat perbedaan signifikan terhadap kandungan flavonoid total dari kedua kelompok perlakuan.
Antioxidan Activity from Methanol Extract of Kratom Leaves (Mitragyna speciosa) Maseration Result Using The DPPH Method: Aktivitas Antioksidan Ekstrak Metanol Daun Kratom (Mitragyna speciosa) Hasil Maserasi Menggunakan Metode DPPH Andhika Dwi Aristyawan; Anggi Ayu Windari; Mercyska Suryandari; Galuh Gondo Kusumo
Journal Pharmasci (Journal of Pharmacy and Science) Vol. 8 No. 2 (2023): Journal Pharmasci (Journal of Pharmacy and Science)
Publisher : Akademi Farmasi Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53342/pharmasci.v8i2.357

Abstract

Antioxidants are compounds that can prevent the formation of free radicals. Kratom is a typical plant from South Putussibau area, in West Kalimantan. The kratom plant contains alkaloids, triterpenoid-steroids, saponins, tannins and flavonoids. The main component of kratom leaves is an indole alkaloid that is efficacious as an antioxidant. The goal is to determine the antioxidant activity of kratom leaf extract (Mitragyna speciosa). The method used is the measurement of the reduced amount of DPPH from an antioxidant compound UV-Vis spectrophotometrically at a wavelength of 517nm using Vitamin C as a comparison. The extraction method used is maceration. The test was sampled 10 mg of kratom leaf extract (Mitragyna speciosa) with 10 ppm, 20 ppm, 30 ppm, 40 ppm, and 50ppm concentrations, then repeated 3 times. The results of the antioxidant activity of kratom leaves (Mitragyna speciosa) were expressed with IC50 values of 44,169 ± 0.5313 with an RSD value of 1.202%. Then it can be concluded that kratom leaf methanol extract (Mitragyna speciosa) has a very strong antioxidant activity with an IC50 value of 44,169 ± 0.5313 with an RSD value of 1.202%.
SKRINING FITOKIMIA EKSTRAK ETANOL 80% ROSEMARY (Rosmarinus officinalis L.) DENGAN METODE EKSTRAKSI DIGESTI Evi Priyatno; Mercyska Suryandari
Jurnal Komunitas Farmasi Nasional Vol. 2 No. 1 (2022): Jurnal Komunitas Farmasi Nasional
Publisher : Akademi Farmasi Yarsi Pontianak

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Rosemary (Rosmarinus officinalis L.) in the Lamiacea family is one of the herbal plants that has medicinal properties. Based on its potential benefits, a phytochemical screening study was conducted to determine the class of secondary metabolites contained in it and to test the ability of 80% ethanol for extracting secondary metabolites from rosemary extract using the digestion extraction method. The filtrate was then concentrated using a rotary evaporator and phytochemical screening tests were carried out by observing the presence of color changes, formation of precipitates, and the formation of stable foam using certain reagents. The results showed that the ethanol extract of 80% rosemary was positive for terpenoids, alkaloids, flavonoids, saponins, tannins, and polyphenols
Identification of Secondary Metabolites of Garlic Peels Extract (Allium sativum) Mercyska Suryandari Mercyska; Galuh Gondo Kusumo; Ade Ferdinan
Jurnal Komunitas Farmasi Nasional Vol. 2 No. 2 (2022): Jurnal Komunitas Farmasi Nasional
Publisher : Akademi Farmasi Yarsi Pontianak

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

The use of garlic often only makes use of the root part, while the garlic skin is often thrown away without optimal utilization and ends up as waste. Garlic skin has the potential to be developed as a treatment, one of which is for cholesterol because it contains phytochemical compounds. Previous studies have shown that using different solvents during the extraction process will produce different secondary metabolites. So the purpose of this study was to find out the secondary metabolites of garlic skin extract (Allium sativum L.) qualitatively when extracted using 5 different solvents. In this research, the method used was phytochemical screening on garlic skin extract (Allium sativun L.). n-Hexane, Ethyl Acetate, Acetone, 96% Ethanol, and Chloroform using remaceration extraction method separately. The results showed that the yield value was 0.90%; 1.34%; 1.00%; 3.90%; 1.20%. The results showed that the n-Hexane extract of garlic (Allium sativum L.) peels contained steroids and terpenoids; ethyl acetate extract contains alkaloids, steroids and terpenoids; acetone extract contains saponins, steroids, terpenoids and tannins; 96% ethanol extract contains alkaloids, flavonoids, saponins, terpenoids, and tannins; and finally the chloroform extract of garlic skin contains alkaloids, steroids, terpenoids and tannins. So it can be concluded that the secondary metabolites in garlic peel extract contain alkaloids, flavonoids, saponins, steroids, terpenoids and tannins.the study, methods, results and conclusions, can describe qualitatiive and quantitative information.
Edukasi Manfaat Tanaman Piperaceae dan Pelatihan Pembuatan Hand Sanitizer Alami kepada Siswa SMK Farmasi Surabaya Meyke Herina Syafitri; Mercyska Suryandari; M.A. Hanny Ferry Fernanda
Nusantara: Jurnal Pengabdian kepada Masyarakat Vol. 3 No. 2 (2023): Mei : Jurnal Pengabdian Kepada Masyarakat
Publisher : Lembaga Pengembangan Kinerja Dosen

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55606/nusantara.v3i2.1226

Abstract

Betel leaves contain phenols that function as powerful antiseptics. Hand sanitizer (HS) is a product that can kill parasites on the hands and is easy to use. Therefore, in this event, education will be provided to the students of SMK Farmasi Surabaya regarding the benefits of betel leaves, followed by a training session on making hand sanitizers containing extract. The participant's level of understanding is evaluated by comparing the scores obtained before and after receiving information from the speaker. A questionnaire is given to allow participants to evaluate the overall conduct of the event, and they are invited to try the hand sanitizers prepared by the team. The results show that 76% of the participants achieved higher scores, 24% maintained the same scores, and none of the participants received lower scores compared to the pre-test. Overall, the participants expressed that the event was very beneficial.
Fraksinasi dan Identifikasi Ektrak Daun Mitragyna Speciosa Menggunakan Metode Kromatografi Fernanda, M.A. Hanny Ferry; Suryandari, Mercyska; Sudarwati, Tri Puji Lestari
FARMASIS: Jurnal Sains Farmasi Vol 2 No 2 (2021): Farmasis : Jurnal Sains Farmasi
Publisher : Universitas PGRI Adi Buana, Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36456/farmasis.v2i2.4072

Abstract

Background: Mitragyna Speciosa or better known as Kratom is a typical plant from the Putusibau area, West Kalimantan. The most widely used part of this plant is the leaves. The kratom plant contains alkaloids, flavonoids, phenols, terpenoids-steroids, triterpenoids, saponins, and tannins. Alkaloid content is the most dominant and has benefits in this plant so it is necessary to do fractionation and identification of secondary metabolites. Objective: To fractionate and identify secondary metabolites from Mitragyna Speciosa leaf extract. Methods: The fractionation method was carried out using Column Chromatography while for identification using Thin Layer Chromatography. Results: 80 fractions were obtained from the column chromatography results, while the results of identification using thin layer chromatography showed that only the 2nd and 3rd fractions were obtained. The second fraction has two spots with Rf values of 0.51 and 0.73 and in the third fraction there are three spots with Rf values of 0.21; 0.52, and 0.74. Conclusion: Fractionation and identification by chromatographic method can be used as initial screening for secondary metabolite content in Mitragyna Speciosa leaf extract.
Co-Authors Achmad Mustofa Ade Ferdinan Alfiana, Silvina Sita Ana Safitri Andik Isdianto Anggi Ayu Windari Ari Anggraini, Nony Aristyawan, Andhika Dwi Avanti, Christina Berliana, Dini Cicik Herlina Yulianti Desy Irawati Devientasari, Chinthia Dwi Rahayu, Risma Dwi Wahyuniati Eliza Stepanie Romadhona Ernawati, Iin Evi Priyatno Eziah Ika Lubada Fatiya Nur Azifah Fernanda, M.A. Hanny Ferry Fitrianti, Novariza Galuh Gondo Kusumo Hatidja, Siti Annurijati Jessica Aparawidya Diaksa Jezzita Aureola Martha Kharisma Ilmi Nabilah Kinanti Ayu Puji Lestari Kinanti Lestari Lailatus Sa’diyah M.A Hanny Ferry Fernanda M.A. Hanny Ferry Fernanda Meyke Herina Syafitri Ngurah Rio Juliana, I Made Nia Dwi Wahyuning Arum Nur Indahwati, Sephia Permatasari, Silfiana Nisa Putra, Deddy Aryanda Rahma Faradillah Rizky Darmawan Rizky Darmawan Sari, Silfiana Nisa Permata Septi Fandinata, Selly Siti Annurijati Hatidja Sri Safitri Surahmaida, Surahmaida Syafika Rani, Noor Tri Puji Lestari Sudarwati Ulfa, Ninik Mas Umarudin, Umarudin Wefa, Ali Wulansari, Silvi ayu Yuliarni, Floreta Fiska Zenia Nirmala Bintang