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All Journal Community Development Journal: Jurnal Pengabdian Masyarakat Jurnal Mandala Pengabdian Masyarakat Jurnal Pengabdian Masyarakat Indonesia Jurnal Penelitian Keperawatan Kontemporer (JPKK) Jurnal Borneo Cendekia
Fristiyanti, Regina Ayu
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Humanities Economics, Econometrics & Finance Education Engineering Health Professions Nursing Public Health Social Sciences Veterinary

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Journal : Jurnal Penelitian Keperawatan Kontemporer (JPKK)

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The Comparison of Oral and Intravaginal Administration of Lactobacillus plantarum Probiotics on Body Weight of Rattus norvegicus with Vulvovaginalis Candidiasis Matin, Nur Sophia; Fristiyanti, Regina Ayu
Jurnal Penelitian Keperawatan Kontemporer Vol 5 No 2 (2025): Februari 2025
Publisher : Program Studi S1 Ilmu Keperawatan dan Ners IKBIS Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59894/jpkk.v5i2.942

Abstract

Background: The prevalence of fungal infections in humans has been recorded to have increased significantly. Several species of fungi in the genus Candida are reported to cause mucosal and systemic infections with high levels of morbidity and mortality. Infections caused by Candida are called candidiasis, one type of which is Vulvovaginal Candidiasis (Vulvovaginal Candidiasis). In the last few decades, Lactobacillus probiotics have become an alternative strategy for treating various types of infections, including L. plantarum. The comparison of effectiveness between oral and intravaginal administration of L. plantarum still needs to be studied, considering that this really determines the success rate of probiotics as supportive therapy in cases of vulvovaginal candidiasis. Objective: To compare body weight gain after oral and intravaginal administration of L. plantarum in vivo. Method: The research was conducted using a pretest posttest randomized experimental group design approach. The L. plantarum given consisted of three concentrations, namely 2,25x1010, 4,5x1010 and 9x1010 CFU/ml. The statistical analysis used was a paired T-test (CI 95%) to measure body weight before and after administration of L. plantarum. Results: There was a significant increase in the body weight of the study sample with oral and intravaginal administration. Conclusion: Probiotic L. plantarum given orally and intravaginally has the potential to be a supportive therapy for vulvovaginal candidiasis infections.
Co-Authors Ahmad, Mukhlisiana Avia Dewi, Yuanita Viva Fazriyah, Nurul Firdaus, Abraham Ahmad Ali Matin, Nur Sophia Permatasari, Ineke Ineke Prayekti, Endah Puspitasari, Mia Rakhmawati, Shafira Cahyani Riza, Mochamad Faishal Rosyida, Naila Irtabaza Sadeli, Syifani Fauzia Sari, Lia Indria Suci Fitriana Pramudya Wardani Yuliana Yuliana Yuwono, Asma' Denaya Psari Zaizafun, Deaneta Salwa