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All Journal Jurnal Biologi Tropis
Senna, Cantika Brilliant
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Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Immunology & microbiology

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Caring for HIV Person in Dermatology Jibriel, Diaz Azhalea; Dharma, Yoga Prawira Wedha Swara; Nuriasti, Rovera; Pambudi, Balqis Prudena Kurnia; Sugiono, Muhammad Rafly Adrian; Febriana, Nanggi Qoriatul; Dwiandika, Rizki Ary; Zulkifli, Yasmin Sabrina; Larasati, A. A. A. Regina; Senna, Cantika Brilliant; Tahriani, Ridha; Arif Zuhan
Jurnal Biologi Tropis Vol. 25 No. 4 (2025): Oktober-Desember
Publisher : Biology Education Study Program, Faculty of Teacher Training and Education, University of Mataram, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jbt.v25i4.10075

Abstract

More than 90% of individuals infected with Human Immunodeficiency Virus (HIV) exhibit skin abnormalities that can serve as important clues for early diagnosis, monitoring disease progression, and assessing the effectiveness of antiretroviral therapy (ART). However, the diverse presentation of skin problems often complicates clinical management. Methods: This article is based on a literature review of various international and national publications on skin manifestations in HIV patients, as well as dermatological management guidelines. The analysis focused on the types of skin infections, non-infectious conditions, side effects of ART, and recommended treatment strategies. Results: The literature review revealed that skin problems in HIV patients include fungal infections (such as candidiasis, dermatophytosis), bacterial (CA-MRSA, syphilis), viral (HSV, VZV, HPV, molluscum contagiosum), and non-infectious conditions such as seborrheic dermatitis, psoriasis, and severe drug reactions. These skin conditions are influenced by a weakened immune system, treatment side effects, and socioeconomic factors. Treatment requires a combination of ART therapy, dermatological care tailored to the type of skin problem, and psychosocial support. Conclusion: Skin manifestations in HIV patients reflect their immune system and quality of life. Comprehensive treatment, including ART, dermatological therapy, and a psychosocial approach, has been shown to be effective in reducing morbidity and stigma. The results of this study underscore the importance of interdisciplinary collaboration to improve treatment outcomes for HIV patients with skin problems in Indonesia.
Current Therapeutic Innovations in the Treatment of Von Willebrand Disease Senna, Cantika Brilliant; Pratiwi, Baiq Bunga Citra; Rizki, Mohammad
Jurnal Biologi Tropis Vol. 25 No. 4 (2025): Oktober-Desember
Publisher : Biology Education Study Program, Faculty of Teacher Training and Education, University of Mataram, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jbt.v25i4.10359

Abstract

Von Willebrand disease (vWD) is the most common hereditary bleeding disorder caused by a deficiency or dysfunction of von Willebrand factor (vWF), a key protein involved in both primary and secondary hemostasis. This study aims to review the current understanding of diagnosis, classification, and management strategies for vWD based on disease type and severity. A literature review approach was employed to analyze recent findings on the pathophysiology, diagnostic criteria, and therapeutic advances related to vWD. Accurate diagnosis remains crucial, as treatment must be tailored to the specific subtype and clinical severity. Current management focuses on increasing circulating levels of vWF and factor VIII through local hemostatic measures, antifibrinolytic agents such as tranexamic acid, desmopressin (DDAVP) for responsive patients, and vWF/factor VIII concentrates for severe cases or DDAVP contraindications. A multidisciplinary perioperative management plan is essential to minimize bleeding risks during surgical or invasive procedures. Despite advances in therapy, challenges persist in early detection and individualized treatment optimization. Comprehensive evaluation, improved clinical awareness, and collaborative care among healthcare providers are vital to enhancing patient outcomes and quality of life.
A Literature Review: Management of Paralysis and Prevention of Acute Respiratory Failure in Guillain-Barré Syndrome Al Qindi, Ahmad Sa'Bi; Senna, Cantika Brilliant; As Shiddiq, Muhammad Hilmy; Yolanda B.S, Moh. Rizky; Zulkifli, Yasmin Sabrina; Belia, Prima
Jurnal Biologi Tropis Vol. 26 No. 3 (2026): in Progress
Publisher : Biology Education Study Program, Faculty of Teacher Training and Education, University of Mataram, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jbt.v26i3.12588

Abstract

Guillain-Barré Syndrome (GBS) is an acute immune-mediated disorder of the peripheral nervous system characterized by progressive muscle weakness and paralysis. In severe cases, respiratory muscle involvement may lead to acute respiratory failure, which remains one of the leading causes of morbidity and mortality in patients with GBS. This literature review aims to discuss the pathophysiology, clinical manifestations, diagnostic approaches, management of paralysis, and strategies for preventing acute respiratory failure in Guillain-Barré Syndrome. A literature review was conducted by analyzing scientific journal articles, textbooks, and international clinical guidelines retrieved from electronic databases. The findings indicate that GBS is the most common cause of acute non-traumatic flaccid paralysis worldwide and is frequently preceded by an infectious illness. Diagnosis is primarily established based on clinical features and supported by cerebrospinal fluid analysis and electrodiagnostic studies, with diagnostic certainty commonly assessed using the Brighton Collaboration Criteria and clinical evaluation guided by the National Institute of Neurological Disorders and Stroke (NINDS) criteria. Respiratory complications occur in approximately 20–30% of patients and often require intensive monitoring and mechanical ventilation. Early recognition of respiratory muscle weakness through serial assessment of respiratory function, prompt airway management, and timely ventilatory support are essential to prevent acute respiratory failure and improve clinical outcomes. A multidisciplinary approach involving neurologists, intensivists, pulmonologists, rehabilitation specialists, and nursing teams is crucial for reducing morbidity and mortality associated with GBS.
Co-Authors Al Qindi, Ahmad Sa'Bi Arif Zuhan As Shiddiq, Muhammad Hilmy Belia, Prima Dharma, Yoga Prawira Wedha Swara Dwiandika, Rizki Ary Febriana, Nanggi Qoriatul Jibriel, Diaz Azhalea Larasati, A. A. A. Regina Nuriasti, Rovera Pambudi, Balqis Prudena Kurnia Pratiwi, Baiq Bunga Citra Rizki, Mohammad Sugiono, Muhammad Rafly Adrian Tahriani, Ridha Yolanda B.S, Moh. Rizky Zulkifli, Yasmin Sabrina