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All Journal Jurnal Biologi Tropis Lombok Medical Journal
Arif Zuhan
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Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Mechanical Engineering Public Health

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Colorectal Cancer: The Impact of Smoking and Alcohol on Risk in West Nusa Tenggara, Treatment, and Prevention Syakir, Syahda Aqila; Arif Zuhan
Jurnal Biologi Tropis Vol. 24 No. 1b (2024): Special Issue
Publisher : Biology Education Study Program, Faculty of Teacher Training and Education, University of Mataram, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jbt.v24i1b.8074

Abstract

: Colorectal cancer (CRC) is the third most common cancer globally and the second leading cause of cancer-related mortality. It results from complex interactions between genetic, environmental, and lifestyle factors, with smoking and alcohol consumption being significant contributors. This study focuses on the correlation between smoking and alcohol consumption with CRC incidence in West Nusa Tenggara (NTB), a province in Indonesia known for its high smoking prevalence (32.79%) and alcohol consumption rate (1.6%). A literature review methodology was employed, systematically collecting data from PubMed, ScienceDirect, Cochrane Library, Google Scholar, and ProQuest using keywords such as "colorectal cancer," "risk factors," "smoking," "alcohol," "management," and "prevention." A total of 35 articles published between 2007 and 2024 were analyzed to provide a comprehensive synthesis of CRC risk factors, management approaches, and prevention strategies. The findings reveal a strong association between smoking and CRC risk, particularly among middle-aged males, while alcohol amplifies the risk synergistically. Despite limited alcohol prevalence, its impact remains substantial. The study emphasizes the importance of targeted public health interventions in NTB, integrating lifestyle modification campaigns and routine screenings to mitigate CRC risks and improve health outcomes in high-risk communities.
The Article Review Penggunaan Aspirin sebagai Faktor Pemicu Sindrom Reye Radwa, Ghaniyyah Atifah; Fatikha Rudia Ahda; Indri Setiawati; Khaula Karima; Ni Made Ayu Shinta Dewi; Arif Zuhan
Lombok Medical Journal Vol. 2 No. 3 (2023): Lombok Medical Journal Volume 2 Nomor 3
Publisher : Faculty of Medicine, Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/lmj.v2i2.3174

Abstract

Reye syndrome (RS) is a rare metabolic disorder which primarily affects children. The disease is generally characterized by acute encephalopathy and fatty degeneration of several parenchymes, especially the liver. Aspirin or acetylsalicylic acid is an over-the-counter drug as a solution to viral infection that would be the trigger for developing this syndrome. Reye syndrome is most commonly caused by viral pathogens like influenza A and B and varicella. Reye syndrome presents signs and symptoms of continued vomiting with or without dehydration, encephalopathy and, in 50% of patients, hepatomegaly. According to the clinical stage developed and modified by Hurwitz, the clinical stage of Reye syndrome is divided in 0-5, including the non-clinical stage (stage 0). The pathophysiological profile of Reye syndrome is unknown. However, it appears to be associated with mitochondrial dysfunction caused by the use of aspirin resulting in impaired fatty acid metabolism, reduced excretion, and impaired hepatic metabolism. A case-control study suggested a strong association between aspirin-taking behavior and the development of Reye's syndrome. A case-control study suggested a strong association between aspirin-taking behavior and the development of Reye's syndrome. This literature will present a discussion of the relationship of aspirin as a trigger for Reye syndrome based on the etiology, pathophysiology, and pharmacodynamics of aspirin.
Caring for HIV Person in Dermatology Jibriel, Diaz Azhalea; Dharma, Yoga Prawira Wedha Swara; Nuriasti, Rovera; Pambudi, Balqis Prudena Kurnia; Sugiono, Muhammad Rafly Adrian; Febriana, Nanggi Qoriatul; Dwiandika, Rizki Ary; Zulkifli, Yasmin Sabrina; Larasati, A. A. A. Regina; Senna, Cantika Brilliant; Tahriani, Ridha; Arif Zuhan
Jurnal Biologi Tropis Vol. 25 No. 4 (2025): in Progress
Publisher : Biology Education Study Program, Faculty of Teacher Training and Education, University of Mataram, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jbt.v25i4.10075

Abstract

More than 90% of individuals infected with Human Immunodeficiency Virus (HIV) exhibit skin abnormalities that can serve as important clues for early diagnosis, monitoring disease progression, and assessing the effectiveness of antiretroviral therapy (ART). However, the diverse presentation of skin problems often complicates clinical management. Methods: This article is based on a literature review of various international and national publications on skin manifestations in HIV patients, as well as dermatological management guidelines. The analysis focused on the types of skin infections, non-infectious conditions, side effects of ART, and recommended treatment strategies. Results: The literature review revealed that skin problems in HIV patients include fungal infections (such as candidiasis, dermatophytosis), bacterial (CA-MRSA, syphilis), viral (HSV, VZV, HPV, molluscum contagiosum), and non-infectious conditions such as seborrheic dermatitis, psoriasis, and severe drug reactions. These skin conditions are influenced by a weakened immune system, treatment side effects, and socioeconomic factors. Treatment requires a combination of ART therapy, dermatological care tailored to the type of skin problem, and psychosocial support. Conclusion: Skin manifestations in HIV patients reflect their immune system and quality of life. Comprehensive treatment, including ART, dermatological therapy, and a psychosocial approach, has been shown to be effective in reducing morbidity and stigma. The results of this study underscore the importance of interdisciplinary collaboration to improve treatment outcomes for HIV patients with skin problems in Indonesia.
Co-Authors Dharma, Yoga Prawira Wedha Swara Dwiandika, Rizki Ary Fatikha Rudia Ahda Febriana, Nanggi Qoriatul Indri Setiawati Jibriel, Diaz Azhalea Khaula Karima Larasati, A. A. A. Regina Ni Made Ayu Shinta Dewi Nuriasti, Rovera Pambudi, Balqis Prudena Kurnia Radwa, Ghaniyyah Atifah Senna, Cantika Brilliant Sugiono, Muhammad Rafly Adrian Syakir, Syahda Aqila Tahriani, Ridha Zulkifli, Yasmin Sabrina