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All Journal Jurnal Biologi Tropis Jurnal Abdi Insani Lombok Medical Journal
Jacob, Lusye Diana
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PELATIHAN DETEKSI DINI NEUROPATI AKIBAT KEMOTERAPI Hunaifi, Ilsa; Primayanti, Ika; Sapta Wardhani, Indah; Briliansy, Briliansy; Anggoro, Joko; Setyawati, Indri; Fesmia, Herodya Lajunee; Ismiana, Baiq Holisatul; Wiracakra, I Gusti Lanang Krisna; Gea, Endah Irnanda Ulfa; Jacob, Lusye Diana; Putri, Siti Noururrifqiyati Juna; Wardi, Bq. Prita Riantiani; Suryani, ⁠Dini; Andiyani, Dinda Zahra Putri
Jurnal Abdi Insani Vol 12 No 9 (2025): Jurnal Abdi Insani
Publisher : Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/abdiinsani.v12i9.2843

Abstract

Cancer is currently a disease that is experiencing significant growth. This has resulted in the number of chemotherapy administrations reaching 9.8 million to 15 million people and increasing by 53%. One of the side effects that can be caused is peripheral nerve disorders called Chemotherapy-Induced Peripheral Neuropathy (CIPN). In connection with the increasing number of cancer patients undergoing chemotherapy and the severe impact on peripheral nerves due to chemotherapy, early detection is very important to prevent severe complications. This training aims to improve the knowledge and skills of medical personnel in the early detection of chemotherapy-induced neuropathy in order to improve the quality of life of patients and reduce complications and disabilities due to neuropathy. This training was carried out in collaboration with the West Nusa Tenggara Province General Hospital and was attended by 62 nurses. The series of training activities included delivering materials and direct practice to patients. Evaluation of participant knowledge was through a pre-test using the Kahoot application and a post-test using the Plataran Sehat application with a pre-test completion time of 5 minutes. The average pre-test score was 59.35, while the average post-test score was 79.35. The simulation sessions are conducted directly with patients using a neuropathy screening questionnaire, accompanied by a physician. The presentation of the material and the simulation sessions are highly beneficial in neuropathy screening, allowing early detection of neuropathy symptoms and prompt treatment.
Klasifikasi dan Faktor Risiko Ruptur Aneurisma Intrakranial; Sebuah Tinjauan Pustaka Baiq Holisatul Ismiana; Putri, Setyawati Asih; Landapa, Raditya Rachman; Jacob, Lusye Diana
Lombok Medical Journal Vol. 4 No. 3 (2025): Lombok Medical Journal
Publisher : Faculty of Medicine, Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/lmj.v4i3.7014

Abstract

Abstract: Intracranial aneurysms are cerebrovascular abnormalities resulting from structural weakness in the arterial wall, which may rupture and lead to aneurysmal subarachnoid hemorrhage (aSAH), a condition associated with high morbidity and mortality rates. The formation of aneurysms is a multifactorial process that culminates in degenerative changes within the vessel wall. Aneurysms are classified based on morphology (saccular, fusiform, dissecting), size (ranging from small to giant), and anatomical location. The mechanism underlying aneurysm rupture can be explained by the concept of wall shear stress (WSS) in cerebral vessels. Other critical risk factors for aneurysm rupture include aneurysm size and location. A thorough understanding of the classification and risk factors for aneurysm rupture is essential to improve preventive management strategies in clinical practice.
Pathophysiology of Cognitive Dysfunction Due to Decompression Sickness in Diver Pratiwi, Baiq Bunga Citra; Suryantarini, Ni Wayan Puspa Wijaya; Satriawan, Wira; Jacob, Lusye Diana; Harahap, Herpan Syafii
Jurnal Biologi Tropis Vol. 25 No. 4 (2025): Oktober-Desember
Publisher : Biology Education Study Program, Faculty of Teacher Training and Education, University of Mataram, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jbt.v25i4.10138

Abstract

Cognitive impairment can occur due to factors that affect the structural and functional integrity of brain areas that specifically play a role in each cognitive domain. Severe cognitive impairment causes morbidity and mortality. One condition that can lead to complications such as a cognitive impairment is Decompression Sickness (DCS). DCS is an important risk for divers and manifestations of cognitive impairment need to be recognized earlier to prevent progression to a more severe stage. The literature used was collected from the Google Scholar, ScienceDirect, and PubMed databases with restrictions: publication year 2015-2025, Indonesian or English languages, and research with human subjects. The results of the literature review indicate that the pathophysiology of cognitive impairment after onset of DCS is still not clearly understood. The principles that are understood so far include the impact of nitrogen gas bubble circulation in cerebral arteries, extensive brain ischemia, white matter damage, and hyperbaric pressure administration can simultaneously improve cognitive function in patients. It can be concluded that neurological symptoms in DCS can develop into severe cognitive impairment if not recognized and treated immediately. The underlying relationship is mainly related to the impact of nitrogen gas embolism, cerebral ischemia, and extensive damage to cognitive areas of the brain.
Co-Authors Andiyani, Dinda Zahra Putri Anggoro, Joko Baiq Holisatul Ismiana Briliansy, Briliansy Fesmia, Herodya Lajunee Gea, Endah Irnanda Ulfa Herpan Syafii Harahap Ilsa Hunaifi, Ilsa Ismiana, Baiq Holisatul Landapa, Raditya Rachman Pratiwi, Baiq Bunga Citra Primayanti, Ika Putri, Setyawati Asih Putri, Siti Noururrifqiyati Juna Sapta Wardhani, Indah Satriawan, Wira Setyawati, Indri Suryani, ⁠Dini Suryantarini, Ni Wayan Puspa Wijaya Wardi, Bq. Prita Riantiani Wiracakra, I Gusti Lanang Krisna