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All Journal Contagion: Scientific Periodical Journal of Public Health and Coastal Health Indonesian Journal of Global Health research KESANS : International Journal of Health and Science Asian Journal of Community Services (AJCS) International Journal of Health and Pharmaceutical (IJHP)
Christine Handayani Tampubolon
Universitas Kristen Indonesia
Chemistry Computer Science & IT Education Health Professions Languange, Linguistic, Communication & Media Medicine & Pharmacology Nursing Physics Public Health Social Sciences

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Alternative Milk Options for Infants with Cow's Milk Allergy: A Systematic Review of Goat's Milk, Plant-Based Milk, and Partially Hydrolyzed Protein Wija, Ida Bagus Eka Utama; Angelica, Chatrine; Hardiyani, Kartika; Felicia, Mildi; Firmansyah, Gogma; Nandya, Galuh; Tampubolon, Christine Handayani
Jurnal KESANS : Kesehatan dan Sains Vol 4 No 12 (2025): KESANS: International Journal of Health and Science
Publisher : Rifa'Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.54543/kesans.v4i12.426

Abstract

Introduction: Cow's milk allergy (CMA) is the most common food allergy occurring in the first year of life. Restriction of cow's milk and dairy products results in decreased macro- and micronutrient intake, especially in infants who are not breastfed. Therefore, alternative milk supplements for supplemental nutrition in CMA must be considered. Methods: This systematic review used PRISMA guidelines with the PICO search strategy, focusing on RCTs, clinical trials, and observational studies. A comprehensive search was conducted to obtain articles published in English between 2010 and 2025 using ScienceDirect, PubMed, SagePub, and Scopus. Result and Discission: Results A total of 2010 publications were retrieved using relevant search terms. After a rigorous three-stage review, nine studies were selected based on inclusion criteria and deemed suitable for in-depth analysis. These studies addressed tolerance and allergic reactions or cross-reactivity following administration of goat's milk, soy isolate, rice isolate, and partially hydrolyzed formula. Conclusion: In infants with CMA, goat's milk can trigger cross-reactivity. Partially hydrolyzed formulas can be an option for oral food challenges to assess tolerance. Plant-based formulas, particularly rice isolate, are the best choice, especially for those with non-severe CMA and CMA who cannot tolerate extensively hydrolyzed and amino acid-containing formulas.
Promotive Activities through Counseling on Immunization as an Effort to Manage Stunting Reviani, Nia; Sitompul, Yunita R.M.B; Sanggul, Andriyani Risma; Lumbantobing, Romauli; Tampubolon, Christine Handayani
Asian Journal of Community Services Vol. 3 No. 4 (2024): April 2024
Publisher : PT FORMOSA CENDEKIA GLOBAL

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55927/ajcs.v3i4.8884

Abstract

Immunization is an effort to actively create/increase a person's immunity against a disease so that if one day they are exposed to the disease they will not become sick or will only experience mild illness. By providing timely immunization, the community can remain protected and VPD outbreaks can be prevented. Diseases that can be prevented by immunization currently still threaten the world because they can cause death and disability. Based on this, it is very necessary to take preventive and promotive actions related to the importance of immunization. The method used in this activity is through socialization and discussions involving expert speakers in their fields with participants consisting of 67 mothers of toddlers. Participants came from three villages in Jatigede sub-district, Sumedang.
The Relationship Between Mothers’ Frequency of Visits to the Posyandu and the Nutritional Status of Toddlers in Jemah Village, West Java, Indonesia Reviani, Nia; Handayani Tampubolon, Christine
Jurnal KESANS : Kesehatan dan Sains Vol 5 No 3 (2025): KESANS: International Journal of Health and Science
Publisher : Rifa'Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.54543/kesans.v5i3.524

Abstract

Introduction: Nutrition is a key determinant of human health and development, especially in the toddler period, when inadequate intake can quickly lead to growth and health problems. Objective: To determine the relationship between the frequency of maternal visits to integrated health posts (Posyandu) and the nutritional status of toddlers in Jemah Village, Jati Gede District, Sumedang Regency. Method: This descriptive analytic study used a cross-sectional design. Data were collected through observation with an accidental sampling technique from 50 mothers and toddlers registered at Posyandu Mawar I–IV in Jemah Village. Result and Discussion: Most mothers were 26–35 years old, had a high school education, and were housewives. Most toddlers had good nutritional status, and 82% of respondents routinely visited the integrated health posts. Statistical analysis showed a significant positive relationship between visit frequency and toddler nutritional status (p = 0.001), indicating a very strong correlation. Conclusions: Routine maternal visits to integrated health posts are strongly associated with better nutritional status among toddlers in Jemah Village.
Hipotiroid Kongenital Ida Bagus Eka Utama Wija; Christine Handayani Tampubolon
International Journal of Health and Pharmaceutical (IJHP) Vol. 6 No. 2 (2026): May 2026
Publisher : CV. Inara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51601/ijhp.v6i2.611

Abstract

Congenital hypothyroidism (HK) is the most common congenital endocrine disorder in children and is the most common cause of preventable mental retradation. The disorder is caused by the absence of thyroid hormones in the womb and is not needed early can cause severe mental retardation. Clinical manifestations in neonates are not specific, but manifestations obtained after birth consist of gestational age> 42 weeks, BBL> 4kg jaundice> 3 days after birth, edema, umbilical hernia, macroglossia, acrocyanosis. The diagnosis can be made for thyroid screening. Thyroid screening in neonates is carried out before being discharged from the hospital, from the 2nd to 4th day of the baby's age, by checking TSH and T4 levels. The dose of the thyroxine hormone is adjusted to the baby's age and also the baby's body weight.
Relationship between Increased Hematocrit Levels and Lowest Platelet Counts with Outcomes of Dengue Fever Patients in Children Christine Handayani Tampubolon; Erida Manalu; Triana Paskah Dewi
Indonesian Journal of Global Health Research Vol 7 No 3 (2025): Indonesian Journal of Global Health Research
Publisher : GLOBAL HEALTH SCIENCE GROUP

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37287/ijghr.v7i3.6189

Abstract

Aedes aegypti mosquitoes carry a virus that causes Dengue Hemorrhagic Fever (DHF), a disease that continues to be a major health concern in Indonesia, particularly for children. Because variations in hematocrit and platelet counts might reveal the severity of the illness, these tests are crucial for both diagnosing and tracking the progression of DHF. The purpose of this study is to create a picture of the patient demographics and to comprehend the association between hematocrit and platelet parameters and the clinical outcomes of juvenile DHF patients. Objective to determine whether there is a relationship between increased hematocrit levels and the lowest platelet count with the outcome of dengue fever patients in children at Ciracas Regional Hospital. This research was conducted through a quantitative descriptive model with a retrospective approach. Data collection was carried out through medical records of pediatric patients with DHF at Ciracas Regional Hospital in 2022-2024, including demographic data, hematocrit, platelet examination results, and patient outcomes. Data analysis through Univariate and Bivariate analysis with the C-Square test. From this research, it can be seen that the majority of patients experienced a decrease in platelets <50,000 and an increase in hematocrit values ≤20%. A significant correlation was found between low platelet levels and an increase of ≤20% in hematocrit levels with patient clinical outcomes with a p value = 0.000. An decreased in plateleft levels and an increased in hematocrited ≤20% are important indicators in determining the clinical outcomes of DHF in children. Patients can recover even with a decrease in platelet levels <50,000, allegedly due to good and appropriate medical intervention, and the low level of increase in hematocrit levels contributes to the patient's clinical outcomes.
Overview of Risk Factors for Pregnant Women from the Incidence of Stunted Children in the Working Area of East Bogor Health Center for the Period November 2024 to April 2025 Keswari Aji Patriawati; Vidi Posdo A. Simarmata; Batara Imanuel Sirait; Christine Handayani Tampubolon
Contagion: Scientific Periodical Journal of Public Health and Coastal Health Vol 8, No 3 (2026): Contagion
Publisher : Universitas Islam Negeri Sumatera Utara, Medan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30829/contagion.v8i3.29667

Abstract

Stunting, a condition in which children fail to grow due to chronic malnutrition, remains a serious public health problem in Indonesia, although its prevalence has decreased from 21.6% in 2022 to 19.8% in 2024, according to the 2024 Indonesian Nutritional Status Survey (SSGI). This study aims to analyze risk factors in pregnant women that contribute to the incidence of stunting in the work area of the East Bogor Health Center in the period November 2024 to April 2025. This study used a descriptive quantitative method, with a population of 52 mothers who had stunted children aged 0-59 months at the East Bogor Health Center. Data collection was conducted via an electronic questionnaire, and the data were analyzed using univariate methods. The results showed that the majority of respondent mothers were aged 20-35 years (78.8%), had a junior high school education (46.2%), and worked as housewives (76.9%). The most stunted children are 25-36 months (28.8%), with the female gender slightly more (50%). Regarding risk factors among pregnant women, 55.8% did not have anemia, and 53.8% routinely took blood-boosting tablets. As many as 82.7% of mothers do not experience Chronic Energy Deficiency (CED). The most common maternal age during pregnancy is 20-35 years (67.3%). Most of the respondents (76.9%) had no history of pregnancy complications, attended regular ANC visits (71.2%), did not experience weight loss during pregnancy (76.9%), and received adequate nutrition (76.9%). Family support was received by 92.3% of respondents, but 53.8% did not receive counseling and information related to pregnancy. This study underscores the importance of interventions from the get-go to prevent stunting, with a focus on nutrition and health education for pregnant women, as well as on improving access to and quality of antenatal services. Keywords: Chronic Energy Deficiency, East Bogor, Overview, Risk Factors, Stunting
The Relationship Between Leukocytosis and Lymphopenia and the Clinical Outcome of Pneumonia in Toddlers Aged 12-59 Months Christine Handayani Tampubolon; Erida Manalu; Audrey Aurora Louisa Tambunan; Wiradi Suryanegara
Contagion: Scientific Periodical Journal of Public Health and Coastal Health Vol 8, No 3 (2026): Contagion
Publisher : Universitas Islam Negeri Sumatera Utara, Medan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30829/contagion.v8i3.29666

Abstract

Pneumonia is an acute infection of the lung parenchyma that commonly affects children under five years of age and remains a leading cause of pediatric morbidity and mortality worldwide. The inflammatory response to pneumonia is accompanied by alterations in hematological parameters, including leukocytosis and lymphopenia, which may reflect disease severity. This study aimed to evaluate the association between leukocyte and lymphocyte counts and clinical outcomes in toddlers hospitalized with pneumonia at Budhi Asih Regional Hospital. This observational analytical study employed a cross-sectional design using medical records of 117 toddlers diagnosed with pneumonia. Leukocytosis was defined as a leukocyte count of >15,500 cells/µL, while lymphopenia was defined as a lymphocyte count of <2,000 cells/µL. Clinical outcomes were categorized as improvement or deterioration. Associations between hematological parameters and clinical outcomes were analyzed using the Chi-square test, and effect sizes were expressed as odds ratios (ORs) with 95% confidence intervals (CIs). Leukocytosis was significantly associated with clinical deterioration (OR = 24.27, 95% CI: 6.97–84.52; p < 0.001). Likewise, lymphopenia was significantly associated with unfavorable clinical outcomes (OR = 3.05, 95% CI: 1.13–8.26; p = 0.024). A significant association was also observed between leukocyte and lymphocyte abnormalities (p = 0.004). Children with leukocytosis and lymphopenia were more likely to experience clinical deterioration than those without these hematological abnormalities. These findings suggest that leukocytosis and lymphopenia are significantly associated with clinical outcomes in toddlers with pneumonia and may serve as useful adjunctive laboratory markers in clinical assessment. However, because of the cross-sectional design, causal or prognostic inferences cannot be established. Prospective longitudinal studies are warranted to validate their predictive value for disease progression and clinical outcomes. Keywords: Clinical outcomes, leukocytes, lymphocytes, toddler pneumonia 
Co-Authors Angelica, Chatrine Audrey Aurora Louisa Tambunan Batara Imanuel Sirait Erida Manalu Felicia, Mildi Firmansyah, Gogma Hardiyani, Kartika Ida Bagus Eka Utama Wija Indah, Louise Kartika Keswari Aji Patriawati Lumbantobing, Romauli Nandya, Galuh Reviani, Nia Sanggul, Andriyani Risma Simarmata, Vidi Posdo Sitompul, Yunita R.M.B Triana Paskah Dewi Wija, Ida Bagus Eka Utama Wiradi Suryanegara