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Alternative Milk Options for Infants with Cow's Milk Allergy: A Systematic Review of Goat's Milk, Plant-Based Milk, and Partially Hydrolyzed Protein Wija, Ida Bagus Eka Utama; Angelica, Chatrine; Hardiyani, Kartika; Felicia, Mildi; Firmansyah, Gogma; Nandya, Galuh; Tampubolon, Christine Handayani
Jurnal KESANS : Kesehatan dan Sains Vol 4 No 12 (2025): KESANS: International Journal of Health and Science
Publisher : Rifa'Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.54543/kesans.v4i12.426

Abstract

Introduction: Cow's milk allergy (CMA) is the most common food allergy occurring in the first year of life. Restriction of cow's milk and dairy products results in decreased macro- and micronutrient intake, especially in infants who are not breastfed. Therefore, alternative milk supplements for supplemental nutrition in CMA must be considered. Methods: This systematic review used PRISMA guidelines with the PICO search strategy, focusing on RCTs, clinical trials, and observational studies. A comprehensive search was conducted to obtain articles published in English between 2010 and 2025 using ScienceDirect, PubMed, SagePub, and Scopus. Result and Discission: Results A total of 2010 publications were retrieved using relevant search terms. After a rigorous three-stage review, nine studies were selected based on inclusion criteria and deemed suitable for in-depth analysis. These studies addressed tolerance and allergic reactions or cross-reactivity following administration of goat's milk, soy isolate, rice isolate, and partially hydrolyzed formula. Conclusion: In infants with CMA, goat's milk can trigger cross-reactivity. Partially hydrolyzed formulas can be an option for oral food challenges to assess tolerance. Plant-based formulas, particularly rice isolate, are the best choice, especially for those with non-severe CMA and CMA who cannot tolerate extensively hydrolyzed and amino acid-containing formulas.
Relationship between Increased Hematocrit Levels and Lowest Platelet Counts with Outcomes of Dengue Fever Patients in Children Tampubolon, Christine Handayani; Manalu, Erida; Dewi, Triana Paskah
Indonesian Journal of Global Health Research Vol 7 No 3 (2025): Indonesian Journal of Global Health Research
Publisher : GLOBAL HEALTH SCIENCE GROUP

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37287/ijghr.v7i3.6189

Abstract

Aedes aegypti mosquitoes carry a virus that causes Dengue Hemorrhagic Fever (DHF), a disease that continues to be a major health concern in Indonesia, particularly for children. Because variations in hematocrit and platelet counts might reveal the severity of the illness, these tests are crucial for both diagnosing and tracking the progression of DHF. The purpose of this study is to create a picture of the patient demographics and to comprehend the association between hematocrit and platelet parameters and the clinical outcomes of juvenile DHF patients. Objective to determine whether there is a relationship between increased hematocrit levels and the lowest platelet count with the outcome of dengue fever patients in children at Ciracas Regional Hospital. This research was conducted through a quantitative descriptive model with a retrospective approach. Data collection was carried out through medical records of pediatric patients with DHF at Ciracas Regional Hospital in 2022-2024, including demographic data, hematocrit, platelet examination results, and patient outcomes. Data analysis through Univariate and Bivariate analysis with the C-Square test. From this research, it can be seen that the majority of patients experienced a decrease in platelets <50,000 and an increase in hematocrit values ≤20%. A significant correlation was found between low platelet levels and an increase of ≤20% in hematocrit levels with patient clinical outcomes with a p value = 0.000. An decreased in plateleft levels and an increased in hematocrited ≤20% are important indicators in determining the clinical outcomes of DHF in children. Patients can recover even with a decrease in platelet levels <50,000, allegedly due to good and appropriate medical intervention, and the low level of increase in hematocrit levels contributes to the patient's clinical outcomes.
Promotive Activities through Counseling on Immunization as an Effort to Manage Stunting Reviani, Nia; Sitompul, Yunita R.M.B; Sanggul, Andriyani Risma; Lumbantobing, Romauli; Tampubolon, Christine Handayani
Asian Journal of Community Services Vol. 3 No. 4 (2024): April 2024
Publisher : PT FORMOSA CENDEKIA GLOBAL

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55927/ajcs.v3i4.8884

Abstract

Immunization is an effort to actively create/increase a person's immunity against a disease so that if one day they are exposed to the disease they will not become sick or will only experience mild illness. By providing timely immunization, the community can remain protected and VPD outbreaks can be prevented. Diseases that can be prevented by immunization currently still threaten the world because they can cause death and disability. Based on this, it is very necessary to take preventive and promotive actions related to the importance of immunization. The method used in this activity is through socialization and discussions involving expert speakers in their fields with participants consisting of 67 mothers of toddlers. Participants came from three villages in Jatigede sub-district, Sumedang.