Article Per Year (5 Year)
p-Index From 2021 - 2026
2.049
P-Index
This Author published in this journals
All Journal Pharmaciana: Jurnal Kefarmasian Media Farmasi : Jurnal Ilmu Farmasi (Journal Of Pharmaceutical Science) Farmasains : Jurnal Ilmiah Ilmu Kefarmasian JRST (Jurnal Riset Sains dan Teknologi) PHARMACY: Jurnal Farmasi Indonesia (Pharmaceutical Journal of Indonesia) Jurnal Kesehatan Tambusai Jurnal Farmasi Sains dan Praktis Edunity: Kajian Ilmu Sosial dan Pendidikan JTH: Journal of Technology and Health Benzena Pharmaceutical Scientific Journal Praeparandi: Jurnal Farmasi dan Sains
Indri Hapsari
Universitas Muhammadiyah Purwokerto
Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Civil Engineering, Building, Construction & Architecture Computer Science & IT Dentistry Economics, Econometrics & Finance Engineering Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Materials Science & Nanotechnology Medicine & Pharmacology Nursing Public Health Social Sciences

Published : 24 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 24 Documents
Search

 1   2   3 
Pemodelan Pelepasan In Vitro Tablet Floating Teofilin Dengan Program Ddsolver Agus Siswanto; Indri Hapsari; Yusni Ulfiani Zulaikha; Eva Rosmawati
PHARMACY: Jurnal Farmasi Indonesia (Pharmaceutical Journal of Indonesia) Jurnal Pharmacy, Vol. 13 No. 01 Juli 2016
Publisher : Pharmacy Faculty, Universitas Muhammadiyah Purwokerto

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

ABSTRAK Disolusi merupakan elemen penting dalam pengembangan obat terutama terkait dengan absorpsi dan bioavailabilitas sediaan. Penelitian ini bertujuan untuk menentukan kinetika pelepasan tablet floating teofilin secara in vitro. Tablet floating teofilin dibuat dengan metode granulasi basah menggunakan bahan tambahan HPMC K4M CR, NaHCO3, laktosa, dan magnesium stearat. Hasil evaluasi sifat fisik menunjukkan bahwa tablet floating teofilin mempunyai bobot yang seragam (CV=1,93%), kekerasan yang baik (8,4 kg), dan kerapuhan yang rendah (0,05%). Evaluasi model pelepasan dengan program DDSolver menggunakan 2 kriteria: 1). Parameter statistik: R2adjusted, mean square error (MSE), weighted sum of squares (WSS), akaike information criterion (AIC), model selection criterion (MSC); 2). Visual goodness of fit (GOF). Hasil evaluasi data disolusi dengan program DDSolver menunjukkan bahwa pelepasan tablet floating teofilin mengikuti persamaan Weibull. Kurva disolusi berbentuk eksponensial dan pelepasan teofilin terjadi melalui mekanisme difusi. Kata kunci: tablet floating teofilin, DDSolver, pemodelan pelepasan obat. ABSTRACT The dissolution is an important element in drug development is mainly related to the absorption and bioavailability. The aim of this study was to determine in vitro dissolution study of theophylline floating tablet release kinetics model. The floating tablets were prepared by a wet granulation method with HPMC K4M CR, NaHCO3, lactose, and magnesium stearate as excipients. The result showed that the theophylline floating tablets had a weight uniformity (CV=1.93%), good hardness (8.4 kg), and low friability (0.05%). Dissolution data were evaluated using DDSolver conducted by 1). Statistical parameters: R2adjusted, mean square error (MSE), weighted sum of squares (WSS), akaike information criterion (AIC), model selection criterion (MSC); 2). Visual goodness of fit (GOF). The results showed that theophylline floating tablets release kinetics followed the Weibull equation. The dissolution curve is exponential shape and theophylline release occurs through a diffusion mechanism. Key words: floating tablet of theophylline, DDSolver, modeling of drug release.
THE EFFECTS OF HANDWASHING HABITS ON HEALTH PROTOCOLS ON SKIN HYDRATION LEVELS AND INCIDENCE OF IRRITANT CONTACT DERMATITIS Sustiawati _; Indri Hapsari; Irsalina Nurul Putri
Jurnal Farmasi Sains dan Praktis Vol 7 No 1 (2021)
Publisher : Universitas Muhammadiyah Magelang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31603/pharmacy.v7i1.4667

Abstract

Background: Handwashing using soap or hand sanitizer is one of the health protocols that must be implemented by society to prevent the spreading of SARS-COV2 virus which can cause pneumonia, acute respiratory syndrome and death. The implementation of health protocols during the COVID-19 pandemic caused the habit of handwashing increase. Hence, it can lead to cause irritant contact dermatitis and dry hand skin due to frequent contact with soap or hand sanitizers. Method: This study is an observational study with the sample from the villager of Banyumas regency. The data collection was taken by cluster random sampling and accidental sampling. Results: Considering the health protocol, most of the villager used to wash their hands regularly and 3 respondents (3.00%) of them did not. 100 respondents took the data and 19 respondents (19.00%) have irritant contact dermatitis and the rest did not. Furthermore, for skin hydration levels with dehydration category (0% - 29%) are 50 respondents (50.00%), normal category (30% - 50%) are 38 respondents (38.00%) and hydration category (51% - 100 %) are 12 respondents (12.00%). Chi-Square analysis showed that there was no significant relationship between handwashing habit and the incidence of irritant contact dermatitis with the value of “P” is 0.394> 0.05 and there was a significant relationship between hand washing habits and skin hydration levels with the value of “P” is 0.010 <0, 05. Conclusion: Handwashing habits have a significant relationship to skin hydration levels.
THE INFLUENCES OF KNOWLEDGE, BEHAVIOUR AND ATTITUDE IN SELECTING POWDER TYPE: THE INCIDENCE OF ACNE VULGARIS Anggita Nur Fauzana; Indri Hapsari; Irsalina Nurul Putri; Githa Fungie Galistiani
Jurnal Farmasi Sains dan Praktis Vol 8 No 2 (May-August 2022)
Publisher : Universitas Muhammadiyah Magelang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31603/pharmacy.v8i2.4668

Abstract

Acne vulgaris is a chronic obstructive and inflammatory skin disease. It occurs in almost all adolescents with a prevalence of 90%. Powder is the most widely used cosmetic in the long term and one of the causes of Acne vulgaris which causes occlusion of pores on the skin surface. The purpose of this study was to analyze the effect of the level of knowledge, attitudes and behavior of choosing the type of powder on the incidence of acne vulgaris in Banyumas Regency. This study was an observational study with data collection techniques using cluster sampling and sampling technique by accidental sampling. The level of knowledge of women in the Banyumas Regency was dominated by the high category as many as 64 respondents (64.0%). The incidence of acne vulgaris out of 100 respondents, 67 (67.0%) of respondents had mild acne vulgaris, 22 respondents (22.0%) had moderate acne vulgaris and 1 respondent (1.0%) had severe acne vulgaris and the rest had no acne vulgaris. Chi-square analysis showed that there was a relationship between knowledge with behavior and attitude in choosing the type of powder to the incidence of acne vulgaris as evidenced by the p value of each variable, namely 0.044 and 0.028 (p <0.05). The level of knowledge with behavior and attitude in choosing the powder type had a significant relationship to the incidence of acne vulgaris in women in Banyumas Regency.
Formula Optimization of Roselle Flower Extract as Clay Facial Soap Hidayah Anisa Fitri; Ghaliyah Kusuma Wardani; Ika Yuni Astuti; Indri Hapsari
JRST (Jurnal Riset Sains dan Teknologi) Volume 9 No. 2 September 2025: JRST
Publisher : Universitas Muhammadiyah Purwokerto

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30595/jrst.v9i2.24495

Abstract

Roselle flower is known rich in anthocyanin compounds that has activities as antipollutants, so it has potential to be developed as clay facial soap. Soap is formed by the saponification reaction between fatty acids and strong bases which generally has high pH properties. The anthocyanin compound in roselle extract is unstable at base pH. In addition, there are crucial parameters such as pH, viscosity and foam stability that must be eligible to be accepted as cleanser product for facial skin. This study aimed to obtain an optimal formula for clay facial soap containing roselle flower extract by optimizing concentration of surfactant SLES and KOH as soap-forming components. Soap basis was made by mixing the base with fatty acid phase. Design Expert 13 software, one-way ANOVA, and T-Test SPSS were used to design, analyze the effect and predict optimum mixed components in the formula so the final product met the ideal parameters. The data of study showed that the optimal formula of roselle flower clay facial soap should have 9.5% of SLES and 5.25% KOH with a desirability value of 1. The optimum formula had organoleptic, homogeneity, pH, viscosity and foam stability parameters that met the requirements.
ANALYSIS OF MEDICATION MANAGEMENT IN THE PHARMACY UNITS OF DISTRICT/CITY HEALTH DEPARTMENTS: LITERATURE REVIEW Aldhi Solihin Abd. Karim; Indri Hapsari; Githa Fungie Galistiani
JTH: Journal of Technology and Health Vol. 3 No. 4 (2026): April: JTH: Journal of Technology and Health
Publisher : CV. Fahr Publishing

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61677/jth.v3i4.831

Abstract

In order to guarantee the availability, fair distribution, and sensible use of medications, drug management at the District/City Health Office Pharmacy Installation is essential. This study uses a literature review methodology to examine several national publications over the last five years in order to investigate various issues and difficulties in drug management at the District/City Health Office Pharmacy Installation. In order to complete the review process, literature pertinent to the subject of drug management in healthcare institutions was chosen using inclusion criteria. Using the terms medication management, pharmaceutical installation, and health office, ten publications were retrieved from Google Scholar and the Garuda Portal (Garda Rujukan Digital). According to the study's findings, planning and procurement, storage and distribution systems, recording and reporting techniques, supervision and assessment, budgetary concerns, and human resource difficulties are the primary obstacles. The implementation of an integrated drug logistics information system, the development of human resource capacity, and more regionally sensitive policies are the goals of improvement initiatives. The study's findings highlight the necessity of a more all-encompassing management approach to ensure the successful, efficient, and sustainable operation of pharmaceutical services at the District/City level.
THE EFFECT OF HOME PHARMACY CARE ON CLINICAL OUTCOMES AND QUALITY OF LIFE IN PATIENTS WITH TYPE 2 DIABETES MELLITUS Ali Nurrohim; Djoko Wahyono; Indri Hapsari
JTH: Journal of Technology and Health Vol. 4 No. 1 (2026): July: JTH: Journal of Technology and Health
Publisher : CV. Fahr Publishing

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61677/jth.v4i1.837

Abstract

Home Pharmacy Care (HPC) is a comprehensive, home-based pharmacy service designed to improve adherence, education, and monitoring for patients with Type 2 Diabetes Mellitus (T2DM) in order to achieve optimal clinical outcomes and a better quality of life. This study aims to evaluate the impact of implementing Home Pharmacy Care on clinical outcomes (such as HbA1c levels, blood pressure, and lipid profiles) as well as the quality of life of T2DM patients. The study used a quasi-experimental design with intervention and control groups, involving 60 patients at Mitra Siaga Hospital, Tegal Regency, Central Java. Clinical outcome and quality of life data were collected before and after the intervention using standardized instruments (WHOQOL-BREF for quality of life). The results of the study showed that the intervention group experienced significant improvements in all parameters compared to the control group (p < 0.05). In the intervention group, there was a mean decrease in HbA1c levels of -1.5% (p = 0.000), a decrease in systolic blood pressure of -14 mmHg (p = 0.001), and improvements in lipid profile characterized by a reduction in total cholesterol of -23 mg/dL (p = 0.002) and LDL by -17 mg/dL (p = 0.003). Additionally, the intervention group’s quality of life score showed a significant overall increase of +11.6 points (p = 0.001), particularly in the dimensions of physical health and social relationships.  These findings suggest that Home Pharmacy Care has the potential to be an effective strategy for the sustainable management of T2DM patients.
OPTIMASI TABLET FLOATING TEOFILIN MENGGUNAKAN METODE DESAIN FAKTORIAL agus siswanto; Indri Hapsari; yusni ulfiani zulaikha; eva rosmawati
Farmasains : Jurnal Ilmiah Ilmu Kefarmasian Vol. 3 No. 1 (2016)
Publisher : Universitas Muhammadiyah Prof. DR. HAMKA

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

ABSTRACTTheophylline is a drug used in the management of asthma. It has relatively short half-life and narrow therapeutic index with 5-20 μg/mL serum concentration. Thus, Floating tablet formulations that can increase the bioavailability of the drug. The aims of this study were to determine the effect of the excipient (HPMC K4M CR and NaHCO3) to the quality of tablets and determine the optimum formula of theophylline floating tablet. A 22 randomized factorial design was used in development of theophylline floating tablet with HPMC K4M CR (A) and NaHCO3 (B) as independent variables.The flowability of mass tablet, floating character, and dissolution profile were chosen as dependent variables.The results showed that NaHCO3 was the most important factor on increasing flowability of mass tablet. HPMC K4M CR was the dominant factor in lowering the Flag time, improving integrity of the tablet, and decreasing the release of drug. The composition of HPMC K4M CR 40.00 mg and NaHCO3 35.39 mg produced the optimum formula of theophylline floating tablet with desirability value of 0.978.
PERAN APOTEKER DALAM IDENTIFIKASI DAN PENANGANAN DRUG RELATED PROBLEMS PADA TUBERKULOSIS nur annisa septyaningrum; Indri Hapsari; Githa Fungie Galistiani
Jurnal Kesehatan Tambusai Vol. 7 No. 2 (2026): JUNI 2026
Publisher : Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/jkt.v7i2.57472

Abstract

Tuberkulosis (TB) merupakan penyakit menular dengan prevalensi tinggi di Asia Tenggara, termasuk Indonesia, dan menjadi salah satu penyebab utama kematian akibat infeksi. Kompleksitas regimen pengobatan TB yang melibatkan penggunaan obat jangka panjang berisiko menimbulkan Drug Related Problems (DRPs), seperti interaksi obat, efek samping, dan ketidakpatuhan pasien terhadap terapi. Tinjauan ini bertujuan untuk mengeksplorasi peran apoteker dalam identifikasi dan penanganan DRPs pada pasien TB berdasarkan literatur terkini. Metode yang digunakan adalah narrative review terhadap 10 artikel ilmiah dalam rentang waktu 2019–2024 dari database bereputasi. Hasil kajian menunjukkan bahwa peran apoteker mencakup identifikasi interaksi obat, edukasi pasien, pemantauan efek samping, serta penguatan kepatuhan melalui intervensi farmasi seperti Medication Therapy Management (MTM) dan program DOTS. Bukti ilmiah menunjukkan bahwa keterlibatan aktif apoteker dapat meningkatkan efektivitas terapi dan keselamatan pasien TB. Oleh karena itu, diperlukan penguatan sistem dan kebijakan kesehatan untuk mendukung optimalisasi peran apoteker dalam praktik klinik pengelolaan TB.
TINJAUAN NARATIF: KEPATUHAN MINUM OBAT DAN FAKTOR KEBERHASILAN TERAPI HIPERTENSI DI PUSKESMAS INDONESIA Saturi; Djoko Wahyono; Indri Hapsari
Praeparandi : Jurnal Farmasi dan Sains Vol 9 No 1 (2025): Praeparandi : Jurnal Farmasi dan Sains
Publisher : Fakultas Farmasi Universitas YPIB

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51997/6gkw4j69

Abstract

Kepatuhan pasien dalam menjalankan pengobatan antihipertensi berperan vital dalam mencapai keberhasilan terapi serta mengontrol tekanan darah secara optimal. Meskipun demikian, beragam penelitian menunjukkan bahwa tingkat kepatuhan pasien hipertensi di Puskesmas masih cukup bervariasi dan dipengaruhi oleh beragam determinan. Tinjauan naratif ini bertujuan mengidentifikasi serta menganalisis faktor-faktor penentu kepatuhan sekaligus hubungannya dengan keberhasilan terapi hipertensi. Dengan menganalisa sembilan artikel ilmiah ditemukan bahwa pengetahuan, motivasi, dukungan keluarga, penggunaan obat herbal, serta karakteristik individu seperti usia, pendidikan, dan pekerjaan memiliki pengaruh signifikan terhadap kepatuhan. Sebagian besar penelitian menggunakan instrumen MMAS-8 sebagai alat ukur utama. Ada hubungan yang kuat antara tingkat kepatuhan dan keberhasilan pengendalian tekanan darah. Oleh karena itu, strategi intervensi edukatif dan penguatan dukungan sosial di Puskesmas sangat diperlukan untuk meningkatkan kepatuhan pengobatan hipertensi.
TINJAUAN NARATIF : EVALUASI PENGELOLAAN OBAT PUSKESMAS DI INDONESIA Wiryanto; Djoko Wahyono; Indri Hapsari
Praeparandi : Jurnal Farmasi dan Sains Vol 9 No 1 (2025): Praeparandi : Jurnal Farmasi dan Sains
Publisher : Fakultas Farmasi Universitas YPIB

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51997/04hp4197

Abstract

Pengelolaan logistik obat yang efektif dan efisien di Pusat Kesehatan Masyarakat (Puskesmas) memegang peranan penting dalam menjamin ketersediaan obat yang bermutu dan tepat waktu bagi masyarakat. Namun, sejumlah studi menunjukkan bahwa pengelolaan logistik obat di tingkat pelayanan primer masih menghadapi berbagai kendala. Tinjauan naratif ini bertujuan untuk mengevaluasi sistem informasi manajemen logistik obat di Puskesmas berdasarkan analisis terhadap sebelas artikel penelitian yang diperoleh dari Google Scholar dan memenuhi kriteria inklusi. Permasalahan utama yang teridentifikasi meliputi aspek perencanaan, pengadaan, distribusi, penyimpanan, kepatuhan terhadap regulasi, serta pemanfaatan dana Jaminan Kesehatan Nasional (JKN). Hasil kajian menunjukkan bahwa sistem pengelolaan logistik obat di Puskesmas masih belum optimal dan membutuhkan penguatan dalam aspek teknis, sumber daya manusia, serta dukungan kebijakan yang konsisten. Rekomendasi perbaikan meliputi integrasi sistem informasi digital antara Dinas Kesehatan dan Puskesmas, peningkatan kapasitas sumber daya manusia melalui pelatihan berkelanjutan, serta optimalisasi alokasi dana JKN dalam perencanaan dan pengadaan obat. Diharapkan, langkah-langkah tersebut dapat mendorong efisiensi pengelolaan obat dan meningkatkan mutu pelayanan kesehatan dasar.
Co-Authors Agus Siswanto Aldhi Solihin Abd. Karim Ali Nurrohim Anggita Nur Fauzana Anis Kusumawati Anjar Mahardian Kusuma Anwar Rosyadi Binar Asrining Dhiani Budiman, Arif Caesar, Rahma Yuanita Chiara Dhinta Desy Sapmaimy Didik Setiawan Dinda Farida Djoko Wahyono Djoko Wahyono eva rosmawati Eva Rosmawati Gayuh Kurniawan Genatrika, Erza Ghaliyah Kusuma Wardani Githa Fungie Galistiani Githa Fungie Galistiani Hidayah Anisa Fitri Ika Yuni Astuti Irsalina Nurul Putri Irsalina Nurul Putri Isna Nurkhikmah nur annisa septyaningrum Pri Iswati Utami R. Adi Soeprijanto Rahma Yuanita Caesar Retno Wahyuningrum Reza Nur Iman Saturi Siti Farah Hardiyati Susmiatun Susmiatun susmiatun, susmiatun Sustiawati _ Wahyu Utaminingrum Wiryanto yusni ulfiani zulaikha Yusni Ulfiani Zulaikha