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All Journal International Journal of Public Health Science (IJPHS) Mutiara Medika: Jurnal Kedokteran dan Kesehatan Biomedika Belitung Nursing Journal KACANEGARA Jurnal Pengabdian pada Masyarakat JSFK (Jurnal Sains Farmasi & Klinis) Jurnal Farmasi Indonesia JKKI : Jurnal Kedokteran dan Kesehatan Indonesia Jurnal Kedokteran Hewan JUKEJ: Jurnal Kesehatan Jompa Berkala Ilmiah Kedokteran dan Kesehatan Masyarakat
Yuantari, Rahma
Universitas Islam Indonesia
Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Education Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Public Health Veterinary

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Skrining Prediabetes Dengan Skoring American Diabetes Association (ADA) Pada Calon Jamaah Haji 2025 Jeem, Yaltafit Abror; Andriani, Russy Novita; Yuantari, Rahma; Asmara, Satria Akbar Putra
JUKEJ : Jurnal Kesehatan Jompa Vol 4 No 2 (2025): JUKEJ: Jurnal Kesehatan Jompa
Publisher : Yayasan Jompa Research and Development

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.57218/jkj.Vol4.Iss2.1851

Abstract

Objective: This study aimed to evaluate the diagnostic validity of the American Diabetes Association (ADA) risk score for prediabetes screening among prospective Hajj pilgrims in 2025.Methods: A diagnostic cross-sectional study was conducted on 232 prospective pilgrims from KBIHU Multazam Addakwah using total sampling. The primary variables were the ADA risk score (cut-off ≥4) and fasting plasma glucose as the reference standard. Data were collected through the ADA risk questionnaire and fasting glucose measurement, then analyzed using ROC curve and diagnostic performance metrics.Results: The prevalence of prediabetes was 10.99%. The ADA risk score demonstrated a sensitivity of 65%, specificity of 57.4%, positive predictive value of 15.8%, negative predictive value of 93%, and overall accuracy of 58.2%. The area under the curve (AUC) was 61.0% (95% CI: 50.7%–71.3%; p=0.042).Conclusion: The ADA risk score shows good exclusion capability for prediabetes but limited discriminatory accuracy, and therefore cannot yet be recommended as a standalone primary screening tool for Indonesian Hajj pilgrims without further modification. Keywords:
COFFEE CONSUMPTION MAY DECREASE THE SERUM CREATININE AND PLASMA MALONDIALDEHYDE LEVELS IN RATS WITH HYPERURICEMIA INDUCED BY A HIGH PURINE DIET Sudiarto, Hilmi Ardian; Yuantari, Rahma; Nur Ahsani, Dwi
Jurnal Kedokteran Hewan Vol 15, No 2 (2021): June
Publisher : Universitas Syiah Kuala

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21157/j.ked.hewan.v15i2.19141

Abstract

The aim of this research was to determine the effect of coffee on creatinine and plasma malondialdehyde (MDA) level in rats fed on high purine diet. A total of 24 male Wistar rats divided into 4 groups of 6 rats each. Beef broth were given to 3 groups (K1, P1, P2) for thirty days. Beef broth administration were followed by giving coffee (caffeinated= P1 or by a decaffeinated= P2, 144 mg/200 g BW). Serum creatinine levels and plasma MDA were examined periodically on day 0, 15, and 30. Data were analyzed by multivariate analysis of variance or MANOVA test (CI= 95%, P0.05). Coffee administration (caffeinated and decaffeinated) may decrease the serum creatinine (day-30, K1= 3.17+ 0.69; P1= 1.63+0.11; P2= 1.14+0.08) and MDA levels (day-30, K1= 9.8+0.28; P1= 5.80+0.55, P2= 3.87+3.26) after 30 days of treatment (P= 0.000 for creatinine and MDA levels in K1, P1, P2 groups). A lower serum creatinine and MDA levels can be found in decaffeinated coffee grup. Coffee consumption for 30 days (especially decaffeinated) may decrease serum creatinine and plasma MDA in rat induced by a high purine diet.
Hubungan Ureum dan Kreatinin Serum dengan Lamanya Terapi Hemodialisis pada Pasien Penyakit Ginjal Kronis (PGK) di RS PKU Bantul Malfica, Muhammad Joddy; Rosita, Linda; Yuantari, Rahma
Berkala Ilmiah Kedokteran dan Kesehatan Masyarakat Vol. 1 No. 1 (2023)
Publisher : Fakultas Kedokteran, Universitas Islam Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20885/bikkm.vol1.iss1.art2

Abstract

Latar Belakang: Penurunan fungsi ginjal yang cukup berat dilihat dari peningkatan dua substansi kimia darah yaitu ureum dan kreatinin serum. Hemodialisis sebagai pengganti ginjal sementara dapat menurunkan kadar ureum dan kreatinin serum yang meningkat pada pasien Penyakit Ginjal Kronik (PGK). Semakin lamanya hemodialisis pada penyakit ginjal kronik diharapkan semakin terkontrol pula kadar ureum dan kreatinin pasien.Tujuan: Mengetahui apakah terdapat hubungan ureum dan kreatinin serum dengan lamanya hemodialisis pada pasien penyakit ginjal kronik di Rumah Sakit PKU Bantul D.I. Yogyakarta.Metode: Penelitian ini merupakan penelitian kuantitatif korelasi dengan pendekatan cross sectional. analisis data menggunakan analisis univariat dan bivariat dilakukan pada bulan November–Desember 2020 dengan sampel sebesar 50 orang yang menggunakan teknik consecutive sampling. Hasil: Nilai ureum dan kreatinin serum pada 50 subjek penelitian ditemukan berada pada kadar tinggi baik laki-laki maupun perempuan dengan nilai rerata ureum masing-masing (40,06 mg/dL & 35,59 mg/dL) dan nilai median kreatinin serum (3,05 mg/dL dan 2,28 mg/dL). Hubungan antara kadar ureum dan kreatinin serum dengan lamanya hemodialisis masing-masing didapatkan p = 0,980 dan p = 0,665.Simpulan: Tidak terdapat adanya hubungan yang bermakna antara ureum dan kreatinin serum dengan lamanya hemodialisis pada pasien penyakit ginjal kronik di RS PKU Bantul.   Kata kunci : Ureum; kreatinin; lama hemodialisis; pasien penyakit ginjal kronis
Evaluating the performance of TAG-IT for prediabetes detection in Indonesian population Jeem, Yaltafit Abror; Yuantari, Rahma; Widiatninda, Hajar Admira; Andriani, Russy Novita; Makkiyyah, Siti Solichatul
International Journal of Public Health Science (IJPHS) Vol 15, No 1: March 2026
Publisher : Intelektual Pustaka Media Utama

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.11591/ijphs.v15i1.26887

Abstract

Early detection of prediabetes plays a critical role in preventing type 2 diabetes mellitus (T2DM), especially within primary care, where access to laboratory testing may be constrained. Non-laboratory-based risk assessment instruments, including the tool to assess the likelihood of fasting glucose impairment (TAG-IT), can facilitate preliminary risk screening. This study sought to determine the diagnostic accuracy of the TAG-IT questionnaire in detecting prediabetes, using the oral glucose tolerance test (OGTT) as the reference standard. A cross-sectional design was implemented across three community health centers in the Special Region of Yogyakarta, Indonesia. Although 308 individuals were initially enrolled, only 93 participants with complete datasets were eligible for final analysis. The discriminative capacity of TAG-IT was evaluated through receiver operating characteristic (ROC) curve analysis along with a contingency table. Among the participants analyzed, 24.7% (23/93) were classified as having prediabetes. The TAG-IT tool exhibited modest discriminatory performance, yielding an AUC of 0.656 (95% CI 0.525-0.786; p = 0.026). Using the identified optimal threshold, sensitivity reached 52.2% while specificity was 67.1%. The negative predictive value was 81.0%, indicating better performance in excluding low-risk individuals. Overall, TAG-IT demonstrated moderate utility as a preliminary screening instrument in primary healthcare, particularly for identifying individuals unlikely to have prediabetes.
Home medication review and drug-related problems in patients with chronic diseases at primary health centers in Yogyakarta, Indonesia: A cross-sectional multicenter study Ningrum, Vitarani Dwi Ananda; Yunilistianingsih; Khotimah, Muslimatul; Shintia, Nirma Atin; Efendi, Septia Rahayu; Dewani, Cindy Pramudyah; Andini, Hana Trisna; Yuantari, Rahma
Belitung Nursing Journal Vol. 12 No. 1 (2026): January - February
Publisher : Belitung Raya Publisher - Belitung Raya Foundation

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33546/bnj.4185

Abstract

Background: The high incidence of Drug-Related Problems (DRPs), including medication adherence among patients with chronic diseases, especially during no direct monitoring by health workers, becomes a challenge to therapy success. Home Medication Review (HMR) is an alternative solution in primary healthcare services to avoid further complications. Objective: This study aimed to analyze DRPs, their affecting factors, and DRP interventions for patients with chronic diseases in primary health centers (Puskesmas) through HMR. Methods: A quantitative, cross-sectional observational study using purposive sampling was conducted in several Puskesmas in Yogyakarta from February to May 2023. The collaborative HMR involved healthcare providers at each Puskesmas. DRPs were assessed based on observations and semi-structured interviews. The DRP classification followed PCNE V9.1, and medication adherence was measured using both pill counts and self-report via the MARS-10 questionnaire. Data were analyzed using SPSS 25.0 to perform logistic regression with a 95% confidence level. Results: A total of 544 patients, comprising 269 adults and 275 older patients, were involved. Older patients experienced more DRPs than the adults (94.2% vs 84.8%). The most DRP experienced by both age groups was ineffective therapies, with the two most frequent causes being related to patient factors. Among the adults, hypertension comorbidity, number of medications, and BMI factors were associated with DRPs (p < 0.05). In contrast, no factors correlated with DRPs in the older patients. There was fair agreement between pill count and MARS-10 regarding medication adherence for both adults and older patients (kappa coefficients of 0.298 and 0.355, respectively). Conclusion: Patients in primary health facilities with hypertension and using at least three medications have over a three-fold increased risk of experiencing DRPs. Healthcare providers, including pharmacists, nurses, and physicians, should collaborate to identify medication-related issues and provide personalized advice and management plans to enhance medication adherence. This study highlights the need for a standardized, structured HMR program, not merely as a patient home visit but also to better control chronic diseases.
Co-Authors Adika Zhulhi Arjana Andini, Hana Trisna Andriani, Russy Novita Ani Khotul Faizah Asmara, Satria Akbar Putra Budi Mulyono Dewani, Cindy Pramudyah Dwi Nur Ahsani Edy Purwanto Efendi, Septia Rahayu Endang Sulistyowatiningsih Faizah, Ani Khotul Firdausia Rahma Putri Hilmi Ardian Sudiarto Ingesti Bilkis Zulfatina Irfan, Rozan Muhammad Irfan, Rozan Muhammad Irwan Nuryana Kurniawan Jeem, Yaltafit Abror Juwariyah Juwariyah Khotimah, Muslimatul Linda Rosita Linda Rosita Makkiyyah, Siti Solichatul Malfica, Muhammad Joddy Mursidha Rakhmi Salicha Ninda Devita Ninda Devita, Ninda Nur Ahsani, Dwi Rahadian Kurniawan Rahayu, Ester Tri Reza Ishak Estiko Rozan Muhammad Irfan Shintia, Nirma Atin Sri Kusumadewi Sudiarto, Hilmi Ardian Sulistyowatiningsih, Endang Vitarani Dwi Ananda Ningrum Widiatninda, Hajar Admira Yunilistianingsih