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All Journal Mutiara Medika: Jurnal Kedokteran dan Kesehatan Biomedika Smart Medical Journal KACANEGARA Jurnal Pengabdian pada Masyarakat JSFK (Jurnal Sains Farmasi & Klinis) Jurnal Farmasi Indonesia JKKI : Jurnal Kedokteran dan Kesehatan Indonesia Jurnal Kedokteran Hewan JUKEJ: Jurnal Kesehatan Jompa
Yuantari, Rahma
Universitas Islam Indonesia
Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Education Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Public Health Veterinary

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COFFEE CONSUMPTION MAY DECREASE THE SERUM CREATININE AND PLASMA MALONDIALDEHYDE LEVELS IN RATS WITH HYPERURICEMIA INDUCED BY A HIGH PURINE DIET Hilmi Ardian Sudiarto; Rahma Yuantari; Dwi Nur Ahsani
Jurnal Kedokteran Hewan Vol 15, No 2 (2021): June
Publisher : Universitas Syiah Kuala

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21157/j.ked.hewan.v15i2.19141

Abstract

The aim of this research was to determine the effect of coffee on creatinine and plasma malondialdehyde (MDA) level in rats fed on high purine diet. A total of 24 male Wistar rats divided into 4 groups of 6 rats each. Beef broth were given to 3 groups (K1, P1, P2) for thirty days. Beef broth administration were followed by giving coffee (caffeinated= P1 or by a decaffeinated= P2, 144 mg/200 g BW). Serum creatinine levels and plasma MDA were examined periodically on day 0, 15, and 30. Data were analyzed by multivariate analysis of variance or MANOVA test (CI= 95%, P0.05). Coffee administration (caffeinated and decaffeinated) may decrease the serum creatinine (day-30, K1= 3.17+ 0.69; P1= 1.63+0.11; P2= 1.14+0.08) and MDA levels (day-30, K1= 9.8+0.28; P1= 5.80+0.55, P2= 3.87+3.26) after 30 days of treatment (P= 0.000 for creatinine and MDA levels in K1, P1, P2 groups). A lower serum creatinine and MDA levels can be found in decaffeinated coffee grup. Coffee consumption for 30 days (especially decaffeinated) may decrease serum creatinine and plasma MDA in rat induced by a high purine diet.
Pengembangan dan Validasi Kuesioner untuk Menilai Miskonsepsi tentang Pengobatan pada Hipertensi dan Diabetes Melitus dengan Kejadian Gagal Ginjal Kurniawan, Irwan Nuryana; Yuantari, Rahma; Sulistyowatiningsih, Endang; Faizah, Ani Khotul; Ningrum, Vitarani Dwi Ananda
JSFK (Jurnal Sains Farmasi & Klinis) Vol 7 No 3 (2020): J Sains Farm Klin 7(3), Desember 2020
Publisher : Fakultas Farmasi Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jsfk.7.3.202-209.2020

Abstract

Miskonsepsi tentang pengobatan menjadi salah satu faktor tingginya ketidakpatuhan pengobatan. Masyarakat beranggapan bahwa penggunaan obat rutin pada hipertensi dan diabetes mellitus (DM) dapat menyebabkan gagal ginjal. Penelitian ini bertujuan untuk menyediakan kuesioner valid dan reliabel yang dapat digunakan untuk mengukur miskonsepsi masyarakat tentang pengobatan jangka panjang pada hipertensi dan DM dengan kejadian gagal ginjal. Pengembangan kuesioner dilakukan dalam 5 tahap yakni konseptualisasi, konstruksi alat ukur, uji coba melalui studi 1 pada 240 mahasiswa/i medis dan non-medis, dan studi 2 pada 300 masyarakat di wilayah Kabupaten Sleman, tes revisi dan selanjutnya tahap analisis melalui uji reliabilitas alpha cronbach. Sementara itu, uji validitas dilakukan dengan membandingkan kuesioner ini dengan kuesioner terpercaya lainnya. Hasil skala pengetahuan tentang terapi hipertensi dan DM terkait kejadian gagal ginjal pada studi 1 dan studi 2 tersusun atas 4 variabel pengetahuan meliputi: pengetahuan terapi hipertensi dan DMT (α 0.742, α 823), miskonsepsi penggunaan obat rutin (α 0.835, α 0.805), pengetahuan obat penyebab gagal ginjal (α 0.582), (α 0.581), serta pengetahuan faktor risiko gagal ginjal (α  0.721, α 0.698). Hasil analisis ini menunjukkan bukti awal dan menyediakan instumen valid dan relevan untuk mengukur tingkat miskonsepsi masyarakat tentang pengobatan jangka panjang pada hipertensi dan DM terkait dengan gagal ginjal.
Skrining Prediabetes Dengan Skoring American Diabetes Association (ADA) Pada Calon Jamaah Haji 2025 Jeem, Yaltafit Abror; Andriani, Russy Novita; Yuantari, Rahma; Asmara, Satria Akbar Putra
JUKEJ : Jurnal Kesehatan Jompa Vol 4 No 2 (2025): JUKEJ: Jurnal Kesehatan Jompa
Publisher : Yayasan Jompa Research and Development

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.57218/jkj.Vol4.Iss2.1851

Abstract

Objective: This study aimed to evaluate the diagnostic validity of the American Diabetes Association (ADA) risk score for prediabetes screening among prospective Hajj pilgrims in 2025.Methods: A diagnostic cross-sectional study was conducted on 232 prospective pilgrims from KBIHU Multazam Addakwah using total sampling. The primary variables were the ADA risk score (cut-off ≥4) and fasting plasma glucose as the reference standard. Data were collected through the ADA risk questionnaire and fasting glucose measurement, then analyzed using ROC curve and diagnostic performance metrics.Results: The prevalence of prediabetes was 10.99%. The ADA risk score demonstrated a sensitivity of 65%, specificity of 57.4%, positive predictive value of 15.8%, negative predictive value of 93%, and overall accuracy of 58.2%. The area under the curve (AUC) was 61.0% (95% CI: 50.7%–71.3%; p=0.042).Conclusion: The ADA risk score shows good exclusion capability for prediabetes but limited discriminatory accuracy, and therefore cannot yet be recommended as a standalone primary screening tool for Indonesian Hajj pilgrims without further modification. Keywords:
Co-Authors Adika Zhulhi Arjana Andriani, Russy Novita Ani Khotul Faizah Asmara, Satria Akbar Putra Budi Mulyono Dwi Nur Ahsani Edy Purwanto Endang Sulistyowatiningsih Ety Sari Handayani Faizah, Ani Khotul Farah Jasmine Dianita Firdausia Rahma Putri Hilmi Ardian Sudiarto Ingesti Bilkis Zulfatina Irfan, Rozan Muhammad Irfan, Rozan Muhammad Irwan Nuryana Kurniawan Jeem, Yaltafit Abror Juwariyah Juwariyah Linda Rosita Linda Rosita Mursidha Rakhmi Salicha Ninda Devita Ninda Devita, Ninda Rahadian Kurniawan Rahayu, Ester Tri Reza Ishak Estiko Rozan Muhammad Irfan Sri Kusumadewi Sulistyowatiningsih, Endang Vitarani Dwi Ananda Ningrum