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All Journal Buletin Veteriner Udayana
Sri Kayati Widyastuti
Laboratorium Penyakit Dalam Veteriner, Fakultas Kedokteran Hewan Universitas Udayana, Jl. Raya Sesetan, Gg. Markisa No.6, Denpasar, Bali, Indonesia, 80235
Immunology & microbiology Public Health Veterinary

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HISTOLOGICAL STRUCTURE OF LYMPHOCYTES, MONOCYTES IN DOGS WITH DERMATITIS PRE AND POST THERAPY Made Ananda Giri Tanaya; Ni Ketut Suwiti; I Nyoman Suartha; Sri Kayati Widyastuti; Ni Luh Eka Setiasih; I Made Kardena
Buletin Veteriner Udayana Bul. Vet. Udayana. June 2025 Vol. 17 No. 3
Publisher : Fakultas Kedokteran Hewan Universitas Udayana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24843/bulvet.2025.v17.i03.p22

Abstract

A study was conducted to analyse the histological structure of lymphocytes and monocytes in dogs with dermatitis before and after therapy. Dermatitis is skin inflammation that can be caused by bacterial infections, allergies, or environmental factors. This study used 20 dogs with dermatitis that were given a combination of antiparasitic, antibiotic, anti-inflammatory, and antihistamine therapy. Blood samples were taken before and after therapy to be analysed using Morphology of Edge Blood (MDT) staining to observe changes in the histological structure of lymphocyte and monocyte cells. The results showed: before therapy, lymphocytes and monocytes experienced more necrosis (P<0.05) histological structure changes such as pycnosis, karyorexis, and karyolysis. After therapy, there was a decrease in the number of cells that experienced necrosis in lymphocytes, from 8.45 ± 2.08% to 6.85 ± 1.75%. Whereas in monocytes, there was a decrease in the number (P<0.05) of necrotised cells at post- therapy, from 27.5±19.4% to 13.5±10.3%. The conclusion of this study is that the histological structure of lymphocytes and monocytes that experience necrosis is less than cells that do not necrose. The histological structure of the cells showed a lot more normal. The combination therapy used proved effective in improving the structure of lymphocytes and monocytes.
FELINE CLAMYDIOSIS IN DOMESTIC CATS Divina Gracia Aviela; I Putu Gede Yudhi Arjentinia; Sri Kayati Widyastuti
Buletin Veteriner Udayana Bul. Vet. Udayana. February 2025 Vol. 17 No. 1
Publisher : Fakultas Kedokteran Hewan Universitas Udayana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24843/bulvet.2025.v17.i01.p08

Abstract

A common conjunctival disease in kittens is Chlamydiosis. Chlamydia bacteria invade and infect the cells of the conjunctiva causing inflammation and eye discharge. Clinical signs develop within a few days of infection and begin with eye discharge. The aim of this article is to improve the knowledge of veterinary colleagues in managing cases of conjunctivitis in kittens caused by chlamydial bacterial infection. A 5-month-old female local cat weighing 1.6 kg named Chips had complaints of eye swelling, eye redness and continuous tear and eye discharge since it was adopted. The cat showed signs of difficulty opening the eyes. The diagnosis was confirmed by haematology and cytology examination. Cytological examination of the eye discharge swab was positive for Chlamydophila felis. Haematological examination showed leukocytosis, lymphocytosis and thrombocytopenia. The cat was diagnosed with Feline Chlamydiosis. The cat was treated with Erlamycetin Plus Eye Drop (Chloramphenicol and Dexamethasone) one drop twice daily for 14 days. Supportive therapy with immunomodulator Echinacea purpurea (Imboost Kids Syrup 60 ml) was given twice daily for 2.5 ml for 14 days. The therapy showed satisfactory results. On day 14 the cat was declared cured after therapy and routine eye cleaning. It can be concluded that cats with Chlamydiosis can be treated until cured using topical antibiotics and immunomodulators. The importance of early detection and owner understanding of good and healthy environmental conditions to prevent recurrent infections.
THE EFFECTIVENESS OF DEMODICOSIS MANAGEMENT IN PEKING DOGS USING A COMBINATION OF IVERMECTIN AND AMITRAZ I Dewa Made Upadana Kumara; I Putu Gede Yudhi Arjentinia; Sri Kayati Widyastuti
Buletin Veteriner Udayana Bul. Vet. Udayana. February 2025 Vol. 17 No. 1
Publisher : Fakultas Kedokteran Hewan Universitas Udayana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24843/bulvet.2025.v17.i01.p09

Abstract

Demodicosis is a skin disease caused by Demodex mites and is commonly found in dogs. This study aims to evaluate the effectiveness of a combination of ivermectin and amitraz for the treatment of demodicosis in dogs. A three-year-old male Pekingese dog weighing 5.5 kg was presented to the Internal Medicine Laboratory, Faculty of Veterinary Medicine, Udayana University, exhibiting lethargy and hair loss in the back, neck, legs, and extremities. Physical examination revealed alopecia, erythema, skin thickening, oily and scaly skin, a rancid odor, and hyperpigmentation. The dog exhibited a high level of pruritus. Routine hematological examination showed the dog was experiencing anemia and leukocytopenia. The diagnosis was confirmed as demodicosis based on microscopic examination of deep skin scrapings. The prognosis for this case was considered favorable. The dog was treated with subcutaneous ivermectin (Wormectin 0.5 mg/kg BW, PT. Medion Farma Jaya, Bandung, Indonesia) and antihistamine diphenhydramine HCL (Recodryl® 4 mg/kg BW, PT. Global Multi Pharmalab, Semarang, Indonesia). Weekly baths with amitraz (V-Traz Amitraz 12.5%, PT. Olego Mandiri Indonesia, DKI Jakarta, Indonesia) at a concentration of 500 ppm were administered, along with daily oral administration of a skin and coat supplement (Coatex® vetplus, Mega Utama Medica, DKI Jakarta, Indonesia) at a dose of one capsule. After 14 days, the dog’s condition showed improvement, with reduced scratching intensity, decreased erythema, and resolution of the previously oily skin. Supportive therapy was continued for one month, with further evaluation planned. The dog demonstrated significant recovery following the treatment, and intensive care is recommended to prevent reinfection.
SARCOPTES SCABIEI INFECTION ACCOMPANIED BY HYPOCHROMIC MICROCYTIC ANEMIA IN A DOMESTIC DOG Gusti Ayu Putu Ratih Puspasari; Sri Kayati Widyastuti; I Gusti Made Krisna Erawan
Buletin Veteriner Udayana Bul. Vet. Udayana. February 2025 Vol. 17 No. 1
Publisher : Fakultas Kedokteran Hewan Universitas Udayana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24843/bulvet.2025.v17.i01.p21

Abstract

Scabies is a skin infection caused by ectoparasites of the mite type, Sarcoptes scabiei. These mites infect the host's skin by making tunnels in the epidermis layer which will cause itching. This article aims to describe the occurrence of scabiosis due to Sarcoptes scabiei infection in local dogs. A series of examinations to determine the diagnosis, and the therapy given. A case study was conducted on a local male dog, named Boby, aged 4 months who had itching all over his body that had lasted for one month. Physical examination found alopecia, scales, and crusts on the head, hind legs, front legs, both ears, abdomen, back, and tail. Examination using the skin scraping method found Sarcoptes scabiei mites. Hematological examination showed that the case animal had lymphocytosis, monocytosis, granulocytopenia, hypochromic microcytic anemia, and thrombocytosis. Based on anamnesis, clinical examination results, and supporting examinations, the case animal was diagnosed with scabiosis with a prognosis of fausta. The case dog was given causative therapy in the form of ivermectin at a dose of 0.2 mg/kg BW, subcutaneous injection with two administrations at an interval of 28 days, Symptomatic therapy was given subcutaneous injection of diphenhydramine HCl at a dose of 3 mg/kg BW with two administrations at an interval of 28 days, chlorpheniramine maleate at a dose of 0.5 mg/kg BW orally for 14 days. Supportive therapy B-complex was given 1 tablet once a day for 21 days, fish oil as much as 1 tablet once a day for 20 days, and bathed with shampoo containing sulfur (twice a week). The results of treatment for 28 days showed changes in the condition of the case dog improving, pruritus, crusts, scales, lichenification began to decrease. On the 40th day the case dog showed new hair growth. The awareness of pet owners, especially those who keep dogs, must be increased by always maintaining the cleanliness of their dog's cage, eating utensils, and play equipment.
MANAGEMENT OF NOTOEDRES CATI AND FELICOLA SUBROSTRATUS INFESTATION IN A MALE CAT Angela Ivanka Benedicta; Sri Kayati Widyastuti; I Gusti Made Krisna Erawan
Buletin Veteriner Udayana Bul. Vet. Udayana. April 2025 Vol. 17 No. 2
Publisher : Fakultas Kedokteran Hewan Universitas Udayana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24843/bulvet.2025.v17.i02.p18

Abstract

Scabies is a skin disease caused by Notoedres cati mites that is transmitted to cats. Felicola subrostratus is a species of chewing or biting lice that is common in homeless animals or animals in shelters. A domestic cat was examined at the Veterinary Internal Medicine Laboratory, Faculty of Veterinary Medicine, Udayana University with a history of hair loss and itching. The results of the clinical examination showed crusts on the ears, neck, and extremities, accompanied by dandruff on the neck and back areas. Microscopic examination of skin scrapings found Notoedres cati mites. Trichogram examination found Felicola subrostratus lice and eggs. Based on the history, symptoms, physical examination, and supporting examinations, the case cat was diagnosed with scabiosis and Felicola subrostratus infestation with a fausta prognosis. Treatment with ivermectin injection 0.2 mg/kg subcutaneously with two administrations at 14-day intervals. Symptomatic therapy in the form of diphenhydramine HCl 1 mg/kg BW intramuscularly given once a day for two consecutive days and supportive therapy given fish oil for 14 days. Cats are bathed with sulfur soap twice a week. Topical fipronil is given on the 14th day to kill eggs and adult fleas. The treatment given showed good results.
TOXOCARIASIS AND COCCIDIASIS IN DOMESTIC CAT Gusti Agung Ayu Alecia Putri Anugrahaeni; I Putu Gede Yudhi Arjentinia; Sri Kayati Widyastuti
Buletin Veteriner Udayana Bul. Vet. Udayana. December 2025 Vol. 17 No. 6
Publisher : Fakultas Kedokteran Hewan Universitas Udayana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24843/bulvet.2025.v17.i06.p12

Abstract

Toxocariasis and coccidiasis are parasitic diseases frequently found in domestic cats and can cause gastrointestinal disorders such as diarrhea, anorexia, and decreased body condition. This report aims to describe the symptoms, diagnostic methods, and treatment of Toxocara sp. and Isospora sp. infections in a domestic cat. This case discusses Toxocara sp. and Isospora sp. infections in a domestic cat named Mail, who exhibited clinical symptoms of chronic diarrhea, weakness, and changes in stool condition. Examination was conducted through history taking, clinical examination, fecal floatation and sediment tests, and a Complete Blood Count (CBC) examination. The results showed the presence of Isospora sp. oocysts, both sporulated and non-sporulated, and Toxocara sp. eggs, accompanied by anemia and leukocytosis. Therapy using Pyrantel pamoate, Praziquantel, Metronidazole, and iron supplements was given during the treatment period. After 20 days, the cat's condition improved, indicated by more solid stools and increased activity. It was concluded that rapid diagnosis and appropriate therapy can accelerate recovery. Maintaining environmental sanitation, routine deworming, and improving husbandry management are recommended to prevent reinfection.
HISTOLOGICAL STRUCTURE AND HISTOMORPHOMETRY OF THE BALI DUCK OESOPHAGUS IN STARTER PHASE Eunike Beallara Hutapea; Ni Luh Eka Setiasih; Desak Nyoman Dewi Indira Laksmi; Luh Gde Sri Surya Heryani; Ni Nyoman Werdi Susari; Sri Kayati Widyastuti
Buletin Veteriner Udayana Bul. Vet. Udayana. August 2025 Vol. 17 No. 4
Publisher : Fakultas Kedokteran Hewan Universitas Udayana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24843/bulvet.2025.v17.i04.p25

Abstract

Bali duck (Anas sp.) is a native Indonesian duck breed developed in the Bali and Lombok regions. Bali duck have significant potential as producers of eggs and meat, contributing to the fulfilment of animal protein needs of the Indonesian population. This study was conducted to determine the histological structure and histomorphometry of the oesophagus of bali duck during the starter phase. Samples were taken from ducks aged 1 day, 14 days, 28 days, 42 days, and 56 days. Histological sample observations focused on the layers composing the oesophagus. Parameters used for histomorphometry measurements were the thickness of the oesophageal tunica layers and he results of the research on histological structure are presented in a descriptive qualitative form. The results of the research on histomorphometry are presented in a descriptive quantitative form, analysed using Analysis of Variance (ANOVA) and if the results showed a significant difference, were followed by Duncan’s post-hoc test. The study results indicated that histologically, the bali duck oesophagus consists of the tunica mucosa, tunica submucosa, tunica muscularis, and tunica adventitia. Histomorphometry results showed an increase in the thickness of each layer with increasing age, from 1 day, 14 days, 28 days, 42 days, to 56 days. Further studies in different phase employing special staining techniques are required to allow for more detailed identification.
HISTOLOGICAL AND HISTOMORPHOMETRIC ANALYSIS OF THE VENTRICULUS IN BALINESE DUCKS DURING THE STARTER PHASE Ana Angelica Floarta Nasa; Ni Luh Eka Setiasih; Sri Kayati Widyastuti
Buletin Veteriner Udayana Bul. Vet. Udayana. August 2025 Vol. 17 No. 4
Publisher : Fakultas Kedokteran Hewan Universitas Udayana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24843/bulvet.2025.v17.i04.p38

Abstract

Bali ducks are a source of wealth and genetic resources originating from Bali. This study aims to determine the histological and histomorphometric structure of the ventriculus of bali ducks in the starter phase. The samples used consisted of 15 male Bali ducks and 15 female bali ducks aged 1 day, 14 days, 28 days, 42 days, and 56 days. The histological structure was examined using a binocular light microscope, and histomorphometry was measured using the ImageJ application and analyzed with the assistance of SPSS software. The results of this study showed that the histological structure of the bali duck ventriculus consists of the cuticle, mucosa, submucosa, and muscularis. The histomorphometric results indicated that the thickness of the cuticle increased from 153.884 μm to 387.559 μm, the mucosa increased from 420.448 μm to 779.638 μm, the submucosa increased from 56.634 μm to 260.631 μm, and the muscularis increased from 1010.344 μm to 2420.951 μm. The results of the study indicate that there are no differences in anatomical and histological structure in the bali duck ventricle. However, there are histomorphometric differences in the bali duck ventricle at 1 day, 14 days, 28 days, 42 days, and 56 days of age.
HISTOLOGICAL STRUCTURE AND HISTOMORPHOMETRY OF THE BALI DUCK PROVENTRICULUS IN STARTER PHASE Ditha Amelia Himelda Putri; Ni Luh Eka Setiasih; Ni Nyoman Werdi Susari; I Ketut Berata; Luh Gde Sri Surya Heryani; Sri Kayati Widyastuti
Buletin Veteriner Udayana Bul. Vet. Udayana. August 2025 Vol. 17 No. 4
Publisher : Fakultas Kedokteran Hewan Universitas Udayana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24843/bulvet.2025.v17.i04.p17

Abstract

The proventriculus is one of the primary digestive organs in poultry, functioning as a gland responsible for enzymatic digestion through the secretion of hydrochloric acid and pepsinogen. This study aimed to examine the histological structure and histomorphometry of the proventriculus in Bali ducks during the starter phase. Samples were collected from ducks aged 1, 14, 28, 42, and 56 days, totaling 30 individuals (15 males and 15 females). Histological observations were performed using a binocular microscope, while histomorphometric measurements were conducted using the ImageJ application. Histological data were presented descriptively, and histomorphometric data were analyzed using Analysis of Variance (ANOVA) followed by Duncan’s test. The histological structure of the proventriculus consists of the tunica mucosa, tunica submucosa, tunica muscularis, and tunica serosa. All four layers showed increased thickness with advancing age: the tunica mucosa increased from 156.31 µm to 352.31 µm, the tunica submucosa from 1,113.71 µm to 2,270.87 µm, the tunica muscularis from 215.62 µm to 573.62 µm, and the tunica serosa from 132.86 µm to 486.70 µm. No significant differences (p>0.05) were found in the histological structure between male and female ducks. However, significant differences (p<0.05) in histomorphometric measurements were observed among different age groups.
CYSTOLITHIASIS WITH ASSOCIATED HYDRONEFROSIS IN A FEMALE PERSIAN CAT: A CASE REPORT Valerie Xylia Tay; I Nyoman Suartha; Sri Kayati Widyastuti; I Wayan Nico Fajar Gunawan
Buletin Veteriner Udayana Bul. Vet. Udayana. October 2025 Vol. 17 No. 5
Publisher : Fakultas Kedokteran Hewan Universitas Udayana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24843/bulvet.2025.v17.i05.p03

Abstract

This report describes the diagnosis and management of cystolithiasis in an 8-year-old, spayed female Persian cat weighing 2.85 kg. The patient presented with a history of dysuria and hematuria that began nine months post-ovariohysterectomy. The symptoms initially resolved but recurred with greater severity a few days prior to presentation. Diagnostic tests, including urinalysis and ultrasonography, revealed hyperechoic particles within the urinary bladder and calcium oxalate crystalluria. A diagnosis of calcium oxalate cystolithiasis was made. The owner opted for conservative management, which included a prescription urinary diet and a daily herbal supplement (Keji Beling®). Clinical signs, including dysuria, resolved within seven days of treatment. However, calcium oxalate crystalluria persisted on follow-up urinalysis. This case suggests that conservative management can resolve the clinical signs of cystolithiasis, but long-term dietary control remains essential to manage the underlying risk of crystal formation. The role of herbal therapy in managing this condition requires further investigation.
Co-Authors Adithya Fauzan Ana Angelica Floarta Nasa Andri Saputra Angela Ivanka Benedicta Arya Duta Adnyana Ayala Lubiana Naro Desak Nyoman Dewi Indira Laksmi Dionysius Immanuel Ditha Amelia Himelda Putri Divina Gracia Aviela Eunike Beallara Hutapea Gusti Agung Ayu Alecia Putri Anugrahaeni Gusti Ayu Putu Ratih Puspasari I Dewa Made Upadana Kumara I Gede Bagas Upaditha Adresya Kaler I Gede Soma I Gusti Made Krisna Erawan I Kadek Putra Janardana I Ketut Berata I Made Kardena I Nyoman Suartha I Putu Gede Yudhi Arjentinia I Putu Gede Yudhi Arjentinia I Wayan Nico Fajar Gunawan Iwan Ramdani Luh Gde Sri Surya Heryani Made Ananda Giri Tanaya Nevi Ni Ketut Suwiti Ni Komang Wijayani Ni Luh Eka Setiasih Ni Nyoman Werdi Susari Ni Nyoman Werdi Susari Ni Putu Dewi Setia Sari Nyoman Adi Suratma Nyoman Adi Suratma Putu Ayu Sisyawati Putriningsih Putu Devi Jayanti Putu Devi Jayanti Valerie Xylia Tay