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All Journal Biofarmasetikal Tropis (The Tropical Journal of Biopharmaceutical)
Silvana L. Tumbel
Department of Pharmacy, Faculty of Mathematics and Natural Sciences, Christian University of Indonesia in Tomohon
Biochemistry, Genetics & Molecular Biology Chemistry Immunology & microbiology Materials Science & Nanotechnology Medicine & Pharmacology

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Evaluation of Ficus minahassae Fruit Extract as a Natural Agent against Propionibacterium acnes Abigail F. Maarisit; Cliveno Kojongian; Tesalonika Rondonuwu; Intan J. F. Rawung; Reine Kalalo; Arter Supit; Silvana L. Tumbel; Wilmar Maarisit
Biofarmasetikal Tropis (The Tropical Journal of Biopharmaceutical) Vol. 8 No. 1 (2025): April 2025
Publisher : FMIPA UKIT

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55724/jbiofartrop.v8i1.497

Abstract

Ficus minahassae fruit is known to contain bioactive compounds that have the potential to act as antibacterial agents. This study aims to determine the antibacterial activity of Propionibacterium acnes from F. minahassae fruit extract. F. minahassae fruit is extracted using ethanol. Antibacterial activity test using the disc diffusion method. Based on the results of the study, it was obtained that F. minahassae fruit extract was able to inhibit P. acnes bacteria at concentrations of 200, 300, 400, 500, and 600 mg/disc with inhibition zone diameters of 11.68, 13.33, 14.35, 15.47, and 17.82 mm, respectively. F. minahassae fruit extract can be developed as a raw material for drugs, especially anti-bacterial P. acnes, which causes acne.
Antibacterial Activity Of Green Sirih Leaves (Piper betle Linn) Against Propionibacterium Acnes Douglas N. Pareta; Rainhard R. M. Tumiwuda; Silvana L. Tumbel; Wilmar Maarisit; Yessie K. Lengkey; Ferdy A. Karauwan; Mitra W. Timburas
Biofarmasetikal Tropis (The Tropical Journal of Biopharmaceutical) Vol. 8 No. 2 (2025): OKTOBER 2025
Publisher : FMIPA UKIT

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55724/jbiofartrop.v8i2.522

Abstract

Betel is one of the medicinal plants often found around us. Because of its properties as an antiseptic and wound medicine, this plant can be cultivated. This research aimed to determine the antibacterial activity of green betel leaf essential oil against Propionibacterium acnes. This laboratory experimental research used a completely randomized design with three repetitions in five concentration treatments, one positive control and one negative control for Propionibacterium acnes bacteria. The test method used was the agar diffusion method. Data was collected by observing and measuring the inhibition zone on each Petri dish, which was then tabulated. The data obtained were analyzed descriptively. At a concentration of 10µl, green betel leaf essential oil can be an antibacterial agent against Propionibacterium acnes, according to the results of measuring the diameter of the inhibition zone produced.
Co-Authors Abigail F. Maarisit Arter Supit Cliveno Kojongian Douglas N. Pareta Ferdy A. Karauwan Intan J. F. Rawung Mitra W. Timburas Rainhard R. M. Tumiwuda Reine Kalalo Tesalonika Rondonuwu Wilmar Maarisit Yessie K. Lengkey