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All Journal Jurnal Penelitian Pendidikan IPA (JPPIPA) Jurnal Keperawatan Priority Jurnal Ners Jurnal Sains dan Teknologi Proceeding of The International Conference on Health Sciences and Nursing Indonesian Journal of Global Health Research
Suandy Suandy
Universitas Prima Indonesia
Aerospace Engineering Agriculture, Biological Sciences & Forestry Automotive Engineering Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Computer Science & IT Control & Systems Engineering Dentistry Education Electrical & Electronics Engineering Energy Engineering Health Professions Industrial & Manufacturing Engineering Materials Science & Nanotechnology Mathematics Mechanical Engineering Medicine & Pharmacology Nursing Physics Public Health Veterinary

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Efektivitas Ekstrak Bawang Putih Tunggal Terhadap Kadar Gula Darah, HBA1C dan Histopatologi Pankreas Rattus Norvegicus Dislipidemia Suandy Suandy; Ratu Mutiara Raudhatul Jannah; Linda Chiuman
Jurnal Ners Vol. 9 No. 4 (2025): OKTOBER 2025
Publisher : Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/jn.v9i4.50952

Abstract

Penyakit Diabetes Melitus merupakan masalah kesehatan global yang ditandai dengan hiperglikemia, seringkali disebabkan oleh kerusakan sel beta pankreas. Pengobatan diabetes seringkali memiliki efek samping dan biaya yang tinggi, sehingga penelitian mengenai terapi alternatif, seperti ekstrak alami diperlukan. Penelitian ini bertujuan untuk mengevaluasi efektivitas ekstrak bawang putih tunggal (Allium sativum) terhadap kadar gula darah (KGD), HbA1c, dan gambaran histopatologi pankreas pada tikus (Rattus norvegicus) yang mengalami dislipidemia. Penelitian ini menggunakan desain eksperimen dengan desain kelompok pre-test dan post-test menggunakan 24 ekor tikus yang dibagi menjadi empat kelompok perlakuan. Data dianalisis dengan uji normalitas, uji One-way ANOVA, uji Post-Hoc Tukey HSD, uji Kruskal-Wallis, dan Mann-Whitney. Hasil statistic menunjukkan perbedaan KGD yang signifikan antar kelompok pada hari ke-0 (P. 0.001) dan hari ke-28 (P. 0.001). Namun, pada uji Post-Hoc Tukey HSD, tidak ditemukan perbedaan signifikan antara kelompok kontrol positif dengan kelompok dosis 200 mg/kgBB (P. 0.499) dan 400 mg/kgBB (P. 0.866) pada hari ke-28. Pada parameter HbA1c, uji ANOVA menunjukkan tidak ada perbedaan signifikan antar kelompok pada seluruh haripengamatan (P. > 0.05). Secara visual, gambaran histopatologi menunjukkan adanya perbaikan pada struktur pankreas. Secara statistik, pemberian ekstrak bawang putih tunggal tidak menunjukkan perbedaan yang signifikan terhadap kadar KGD, HbA1c, maupun histopatologi pankreas pada tikus yang diuji.
Effectiveness of Single Garlic Extract on Fatty Liver and Liver Enzymes in Rattus Norvegicus Wistar Fahmi Syahputra; Suandy Suandy; Linda Chiuman
Jurnal Ners Vol. 10 No. 1 (2026): JANUARI 2026
Publisher : Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/jn.v10i1.52285

Abstract

This study investigated the hepatoprotective efficacy of ethanol-extracted single garlic (EEBPT) on fatty liver and hepatic enzymes in rats. A true experimental design with pretest-posttest control group approach was employed. Twenty-four male Wistar rats (Rattus norvegicus) were randomly allocated into four groups: negative control (distilled water), positive control (simvastatin 2.1 mg/kg body weight), low-dose EEBPT (200 mg/kg body weight), and high-dose EEBPT (400 mg/kg body weight). All animals received high-fat diet supplementation for four weeks. Serum aspartate aminotransferase (SGOT/AST) and alanine aminotransferase (SGPT/ALT) were measured on days 0, 14, 21, and 28. Hepatic histopathology was assessed using hematoxylin and eosin staining. One-way ANOVA with Tukey post-hoc test and Kruskal-Wallis test were applied for statistical analysis (p<0.05). Results demonstrated that high-dose EEBPT significantly reduced SGOT and SGPT levels equivalent to simvastatin treatment and ameliorated hepatic steatosis, hepatocyte ballooning, and inflammatory infiltration. Ethanol-extracted single garlic at 400 mg/kg body weight exhibited hepatoprotective effects comparable to conventional statin therapy through antioxidative and anti-inflammatory mechanisms. Garlic extract represents a promising natural hepatoprotective agent for NAFLD management
The Effect of Age and Length of Stay on the Incidence of Ventilator Associated Pneumonia (VAP) in the ICU of Royal Prima Ayahanda Hospital During the 2022-2024 Period Faskanita Maristella Nadapdap; Talitha Syifa; Suandy Suandy
Jurnal Penelitian Pendidikan IPA Vol 11 No 11 (2025): November
Publisher : Postgraduate, University of Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jppipa.v11i11.13255

Abstract

Veintilatoir-assoiciateid pneiumoinia (VAP) is thei moist coimmoin noisoicoimial infeictioin affeicting patieints in inteinsivei carei units. Veintilatoir-assoiciateid pneiumoinia (VAP) is deifineid as pneiumoinia that oiccurs 48 hoiurs oir moirei afteir thei initiatioin oif meichanical veintilatioin. Thei aim oif this study was deiteirminei thei reilatioinship beitweiein agei and thei incideincei oif VAP, as weill as thei reilatioinship beitweiein thei leingth oif hoispital stay and thei incideincei oif VAP amoing ICU patieints at Roiyal Prima Ayahanda Hoispital during thei 2022-2024 peirioid whoi weirei using meichanical veintilatoirs. This study eimploiyeid a croiss-seictioinal deisign. Thei samplei coinsisteid oif 125 patieints, seileicteid using a coinseicutivei sampling teichniquei. Thei data useid weirei seicoindary data oibtaineid froim meidical reicoirds. Thei statistical teist applieid weirei Fisheir’s Eixact. Thei reisult shoiweid that 12 reispoindeints (9.6%) deiveiloipeid VAP in thei ICU oif Roiyal Prima Ayahanda Hoispital. Statistical analysis reiveialeid a p-valuei oif 0.342 beitweiein agei and thei incideincei oif VAP, and a p-valuei oif 0.003 beitweiein thei leingth oif hoispital stay and thei incideincei oif VAP. Thei coinclusioin oif this study is that theirei is a reilatioinship beitweiein agei and thei incideincei oif VAP, as weill as reilatioinship beitweiein thei leingth oif hoispital stay and thei incideincei oif VAP.
Leadership Style with Paramedic Work Motivation on General Hospital Performance Natalia Natalia; Edy Fachrial; Suandy Suandy; Yohani Theresia; I Nyoman Ehrich Lister
Proceeding of the International Conference on Health Sciences and Nursing Vol. 2 No. 1 (2025): Proceeding of the International Conference on Health Sciences and Nursing
Publisher : Asosiasi Riset Ilmu Kesehatan Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61132/ichsn.v2i1.53

Abstract

This study examines the influence of leadership style and paramedic work motivation on the performance of general hospitals. The research aims to investigate how leadership approaches and motivation levels among paramedics affect hospital outcomes. Using a quantitative approach, data was collected from paramedics working in several general hospitals. The analysis included statistical methods such as regression analysis and mediation analysis to test the direct and indirect effects of leadership style and work motivation on hospital performance. The results showed that leadership style and work motivation significantly affect hospital performance. Specifically, effective leadership and high work motivation among paramedics contributed to improved hospital performance indicators. This study provides insights into how hospital management can improve performance by focusing on leadership development and motivation enhancement strategies. The findings highlight the importance of fostering a supportive leadership environment and promoting work motivation among paramedics to achieve better hospital performance.
The Relationship Between Compulsive-Impulsive Behavior and Online Shopping Among Medical Students Suandy Suandy; Nathasyia Aulia; Yolanda Eliza Putri Lubis
Jurnal Keperawatan Priority Vol. 8 No. 1 (2025)
Publisher : Universitas Prima Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.34012/jukep.v8i1.6417

Abstract

Compulsive and impulsive buying behaviors have become increasingly prevalent in modern society, particularly among medical students who have easy access to online shopping. This study aims to explore the relationship between compulsive and impulsive buying tendencies and online shopping behaviors among students from the Faculty of Medicine at Universitas Prima Indonesia, specifically the Class of 2023. Using an analytical survey method and a cross-sectional approach, data were collected from a purposive sample of 100 students. Questionnaires were administered to assess the levels of compulsive and impulsive buying. The results indicated a significant moderate positive correlation between compulsive and impulsive buying behaviors and online shopping, with a correlation coefficient of r=0.445 (p<0.001). This research aims to enhance the understanding of shopping behavior in the digital era and to assist in developing strategies to prevent unhealthy shopping habits.
Effect of Single-Clove Garlic (Allium Sativum Var. Solo Garlic) Extract on Lipid Profile in Male Wistar Rats with Dyslipidemia” Miranda Winda Sari Sitorus; Suandy Suandy; Linda Chiuman
Indonesian Journal of Global Health Research Vol. 8 No. 2 (2026): Indonesian Journal of Global Health Research
Publisher : GLOBAL HEALTH SCIENCE GROUP

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37287/ijghr.v8i2.889

Abstract

Dyslipidemia, a major risk factor for cardiovascular diseases, is characterized by abnormal lipid profiles. While conventional treatments exist, they often have side effects, leading to a growing interest in natural alternatives. Single-clove garlic (Allium sativum var. solo) contains bioactive compounds known for their antioxidant and lipid-lowering properties. This study aimed to evaluate the effectiveness of single-clove garlic extract in improving the lipid profile, including total cholesterol, triglycerides, HDL, and LDL, in dyslipidemic male Wistar rats. A quasi-experimental pre-test and post-test control group design was used with 24 male Wistar rats using purposive sampling. Dyslipidemia was induced with a high-fat diet for 40 days. The rats were divided into four groups: a positive control (simvastatin), a negative control, and two treatment groups receiving different doses of single-clove garlic extract. Lipid profiles were measured on days 7, 14, 21, and 28. Data were analyzed using one-way ANOVA and Tukey’s HSD post-hoc test. The administration of single-clove garlic extract significantly improved the lipid profile of the rats. Over 28 days, treatment groups showed a significant reduction in total cholesterol, triglycerides, and LDL levels, while HDL levels increased. These changes were comparable to those observed in the positive control group. The findings suggest that single-clove garlic extract is effective in improving the lipid profile in dyslipidemic male Wistar rats.
The Effect of Single Garlic Extract (Allium Sativum Var. Solo Garlic) Administration on Weight Gain in Male Rattus Wistar Rats with Dyslipidemia Miranda Winda Sari Sitorus; Suandy Suandy; Linda Chiuman
INSOLOGI: Jurnal Sains dan Teknologi Vol. 4 No. 5 (2025): Oktober 2025
Publisher : Yayasan Literasi Sains Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55123/insologi.v4i5.6494

Abstract

Background: Dyslipidemia is an abnormal condition (increase or decrease) in cholesterol lipoproteins, including an increase in total cholesterol, triglycerides, and low-density lipoprotein (LDL) levels, as well as a decrease in high-density lipoprotein (HDL) levels. Metabolism plays a role in converting nutrients into compounds necessary for life processes, such as energy sources (ATP). Research Objective: To determine the effect of administering single garlic extract (Allium sativum var solo garlic) on weight gain in male Rattus winstar rats with dyslipidemia. Research Methods: This quasi-experimental study used 24 male Wistar rats, single garlic extract, butter, quail eggs, used cooking oil, and scales. The study population consisted of 24 male Wistar rats, which were divided into four groups of six rats each using Federer's formula. The treatments in this study were: the positive group was given standard feed and simvastatin; the negative group was given standard feed and aquabides; treatment group 1 was given 200 mg/kgBW of single garlic extract; and treatment group 2 was given 400 mg/kgBW of single garlic extract. Body weight assessments were conducted four times, namely on days 7, 14, 21, and 28. The research data analyzed were total cholesterol, LDL count, HDL count, triglyceride count, and body weight. Data were analyzed for normality using the Shapiro-Wilk test, and if normally distributed, continued with a one-way parametric ANOVA test and Tukey HSD post-hoc test. Data were analyzed using IBM SPSS 23 for Windows, with P values < 0.05 interpreted as statistically significant. Research Results: The mean values and standard deviations for the positive group were 234±13.20 on day 7, 223±12.29 on day 14, 231.83±11.99 on day 21, and 227.5±10.15 on day 28. Negative group on day 7 (237.33±18.52), day 14 (240±7.84), day 21 (238.5±17.28) and day 28 (239.16±9.62). Treatment 1 on day 7 (261.5±27.22), day 14 (296±21.63), day 21 (316.33±21.05) and day 28 (334.16±17.03). Treatment 2 on day 7 (290±10.62), day 14 (327.16±7.41), day 21 (344.33±45.39) and day 28 (385.83±13.43). Administration of 400 mg/kgBW single garlic extract significantly (P = 0.02 < 0.05) increased the body weight of rats compared to the positive and negative control groups. Conclusion: Based on the results of this study, single garlic extract in test animals showed an increase in body weight in dyslipidemic rats, indicating the need for further research on the mechanism of weight gain due to the administration of single garlic extract.
Co-Authors Edy Fachrial Fahmi Syahputra Faskanita Maristella Nadapdap I Nyoman Ehrich Lister Linda Chiuman Miranda Winda Sari Sitorus Natalia Natalia Nathasyia Aulia Ratu Mutiara Raudhatul Jannah Talitha Syifa Theresia, Yohani Yolanda Eliza Putri Lubis