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All Journal MPI (Media Pharmaceutica Indonesiana) Scientiae Educatia: Jurnal Pendidikan Sains Jurnal Penelitian Pendidikan IPA (JPPIPA) Jurnal Pendidikan dan Pengajaran Guru Sekolah Dasar (JPPGuseda) FITOFARMAKA: Jurnal Ilmiah Farmasi EKOLOGIA : Jurnal Ilmiah Ilmu Dasar dan Lingkungan Hidup Patria : Jurnal Pengabdian Kepada Masyarakat JSEP (Journal of Science Education and Practice)
D Prasetyorini
Program Studi Biologi, FMIPA, Universitas Pakuan, Bogor
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Education Environmental Science Health Professions Immunology & microbiology Materials Science & Nanotechnology Mathematics Medicine & Pharmacology Physics Public Health Social Sciences Other

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FORMULASI GRANUL INSTAN EKSTRAK HERBA PEGAGAN (Centella asiatica) DAN ANALISIS ASIATIKOSIDA Prasetyorini, -; Lohitasari, Bina; Amirudin, Ahmad
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Publisher : Fakultas Matematika dan ilmu pengetahuan Alam. Universitas Pakuan.

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Abstract

The research was conducted in the month from February until April 2011 in the laboratory of Pharmacy Faculty of Mathematics and Natural Sciences, University Pakuan. The research objective is to make a health drink formulation of herbs gotu kola extract and determine the form of instant granules asiatikosida content. Herb gotu kola is used in this study is the collection BALITRO. In this study of instant granules prepared by wet granulation method and made three formulas are: FI (formula without essence), F II (formula with caramel essence, and F III (formula with mango essence.) Asiatikosida analysis performed on dry ekstrakt by TLC method the scanner. the results showed all formulas have the instant granule flow rate and good Sagat compressibility, organoleptic tests (smell and color), which are the F III, asiotikosida content showed a decrease during processing. Gynecology asiatikosida ekstrakt dry is 1.75% (4.375 mg asiatikosida) , instant granules FI of 0.46% (0.052 mg asiatikosida), F II by 0.68% (0.072 mg asiatikosida), and F III amounting to 0.48% (0.056 mg asiatikosida). Rf value on testing asiatikosida in extracts obtained 0.81 with a standard 0.80. Rf value on testing for FI 0.28 instant granules; FII 0.28, and F III 0.29, the standard used for Rf value of 0.28 Kata kunci :   ekstrak herba pegagan, granul instan, asiatikosida
AKTIFITAS BERBAGAI SEDIAAN BUAH SIRSAK (Annona muricata Linn) DALAM PENURUNAN KADAR ASAM URAT TIKUS PUTIH Sprague-Dawley Prasetyorini, -; Moerfiah, -; Wardatun, Sri; Affandi, -
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Publisher : Fakultas Matematika dan ilmu pengetahuan Alam. Universitas Pakuan.

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Abstract

Research potential of juice, extract ethanol, ethyl acetate extracts with different doses of soursop fruit as down as the asamurat has been performed. The treatment given these supplies juice with doses of 930 mg, 1870 2810 mg and mg: 96% ethanol extract with a dose of 26.79 g/100 ml, 53.58 g/100 ml and 80.37 g/100 ml; and extract with ethyl acetate dose 2.58 g/100 ml, 5.16 g/100 ml and 7.74 g/100 ml. The making of extracts is done with methods of maceration of fruit juice, and squeeze the flesh of the fruit directly with Batiste. The results of qualitative testing all positive preparations contain a flavanoid, alkaloids, tannins, saponins and polyphenols. The content of polyphenols  100 g ingredients for fruit juice, extract 96% ethanol and ethyl acetate extracts of consecutive 0.473 g SAG: SAG 0.324 g; and 0.194 mg SAG. Vitamin C 100 g of ingredients for fruit juice, extract 96% ethanol and ethyl acetate extracts of consecutive 38.24 mg; 30.56 mg; 35.66 mg. for 100 g K Content material to juice, extract the ethanol 96% ethyl acetate extracts and a row of 0.39 g; 0.26 g; 0.22 g. Content of 100 g each Na ingredients for fruit juice, extract the ethanol 96% ethyl acetate extracts and a row of 0.0269 g; 0.0416 g; 0.0436 g. The results showed the treatment given the very real effect of lowering uric acid levels of rats, a third dose of juice lowers blood uric acid levels up to 40%, 96% ethanol extract Dosage dose 53.58 g/100 ml and 80.37 g/100mlserta ethyl acetate extract dosage 7.74 g/100 ml can also lower blood uric acid levels exceed the positive control. Key words:   Uric acid, fruit juice, ethanol and ethyl acetate extract fruit soursop (Annona muricata Linn),
PERBEDAAN STRUKTUR ANATOMI TUMBUHAN PENGHASIL GAHARU Aquilaria spp. DAN Gyrinops versteegii Widoyanti, -; Prasetyorini, -; Ismanto, -
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Publisher : Fakultas Matematika dan ilmu pengetahuan Alam. Universitas Pakuan.

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Abstract

The cross and longitudinal section anatomical structure of Aquilaria malaccensis, A. beccariana, A. decipiens, A. microcarpa and Gyrinops versteegii has been studied using paraffin method following Sass (1951) as well as paraderm section and maceration as described in Cutler (1978). The results showed that there were differences in the type of crystal, the number of neighboring cells, the epidermal cells form on upper and lower leaf surfaces and in stomatal index. Further more the differences were also appeared at fingers pith and niche forms. The stomatal index percentage was different significantly with the highest percentage found in A. decipiens 8.47%, followed by A. beccariana 6.73%; A. microcarpa 3.84%; A. malaccensis 3.49% and the lowest percentage was G. versteegiiie 1.60%. Key words: Aquilaria spp., Gyrinops versteegii, plant anatomy, stomatal index
PERBANDINGAN AKTIVITAS ANTIBAKTERI EKSTRAK ETANOL 30% dan 96% KELOPAK BUNGA ROSELLA (Hibiscus sabdariffaL)TERHADAP BAKTERI Staphylococcus aureus Miranti, Mira; -, Prasetyorini; Suwary, Chrys
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Publisher : Fakultas Matematika dan ilmu pengetahuan Alam. Universitas Pakuan.

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Abstract

Penelitian ini bertujuan untuk mengetahui perbandingan aktivitas antibakteri ekstrak etanol 30% dan 96% kelopak  bunga rosella (Hibiscus sabdariffa L) terhadap bakteri Staphylococcus aureus. Perlakuan yang digunakan adalah konsentrasi ekstrak etanol 30% dan 96% kelopak bunga rosella dengan konsentrasi masing-masing yaitu 20%, 40%, 60% dan 80%, sebagai pembanding digunakan antibiotik amoksisilin 10 ppm. Pengujian aktivitas antibakteri dilakukan dengan menggunakan metode difusi kertas cakram serta uji Konsentrasi Hambat Minimum (KHM) menggunakan metode dilusi padat.Hasil penelitian menunjukkan bahwa aktivitas antibakteri ekstrak etanol 30% dan 96% kelopak bunga rosella berbeda dalam menghambat bakteri Staphylococcus aureus. Ekstrak etanol 96% kelopak bunga rosella lebih aktif dalam menghambat bakteri Staphylococcus aureus karena pada konsentrasi 60% dengan rata-rata lebar daerah hambat sebesar 4,5 mm, sedangkan ekstrak etanol 30% kelopak bunga rosella paling aktif pada konsentrasi 80% dengan ratarata lebar daerah hambat sebesar 4,5 mm. Hasil lebar daerah hambat untuk konsentrasi 60% pada ekstrak etanol 96% dan konsentrasi 80% pada ekstrak etanol 30% memiliki pengaruh yang sama secara statistik terhadap kontrol positif amoksisilin dengan rata-rata lebar daerah hambat sebesar 4,6 mmHasil uji konsentrasi hambat minimum (KHM) yang efektif adalah pada konsentrasi 2,5% untuk ekstrak etanol 30% dan konsentrasi 1% untuk ekstrak etanol 96%. Berdasarkan hasil pengujian fitokimia diketahui bahwa ekstrak  etanol 30% dan 96%  kelopak  bunga rosella mengandung saponin, tanin dan flavonoid yang memiliki aktivitas antibakteri.
ANALISIS KANDUNGAN TIMBAL, TEMBAGA DAN ARSEN PADA DAUN KANGKUNG (Ipomoea aquatica) YANG DIJUAL DI TEMPAT YANG BERBEDA DENGAN METODE SPEKTROFOTOMETRI SERAPAN ATOM Prasetyorini, -; Wardatun, Sri
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Publisher : Fakultas Matematika dan ilmu pengetahuan Alam. Universitas Pakuan.

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Abstract

Kangkung merupakan sumber gizi yang murah harganya dan mudah untuk mendapatkannya. Kangkung yang ditanam dan disiram dengan air yang tercemar kemungkinan besar akan mengandung logam pencemar tersebut. Penelitian ini menganalisis kandungan logam pencemar pada kangkung yang dijual di pasaran dengan metode spektrofotometri serapan atom (AAS). Hasil menunjukkan bahwa kangkung yang dijual di pasaran mengandung logam timbal, arsen dan tembaga dengan kadar  di bawah kisaran maksimum  yang diijinkan dalam pangan.  Kata kunci : Kangkung, logam berat, AAS
PENERAPAN TEKNOLOGI NANOPARTIKEL PROPOLIS TRIGONA SPP ASAL BOGOR SEBAGAI ANTIBAKTERI ESCHERICHIA COLI SECARA IN-VITRO Prasetyorini, -; Hasan, AE. Zainal; Siregar, Rofiqoh
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Publisher : Fakultas Matematika dan ilmu pengetahuan Alam. Universitas Pakuan.

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Abstract

Penelitian penerapan nanopartikel propolis Trigona spp asal Bogor sebagai antibakteri Escherichia coli secara in-vitro bertujuan membuat sediaan nanopartikel dari propolis Trigona spp asal Bogor (nanopropolis). Pembuatan nanopropolis dilakukan dengan cara penyalutan dan homogenizer pada kecepatan 22.000 rpm selama satu jam. Dalam penelitian ini dilakukan melalui empat tahap, yaitu tahap ekstraksi raw propolis Trigona spp, tahap pembuatan sediaan nanopropolis, tahap melakukan uji aktivitas nanopropolis sebagai antibakteri dan menentukan konsentrasi hambat tumbuh minimum (KHTM) nanopropolis terhadap bakteri Escherichia coli. Hasil penelitian menunjukkan bahwa Propolis Trigona spp asal Bogor dapat dibuat nanopartikel dengan ukuran partikel mencapai 192 – 273 nm. Ukuran partikel nanopropolis dideteksi menggunakan Scanning Electron Microscopy. Hasil uji aktivitas antibakteri menunjukkan bahwa pada konsentrasi 0,02%-10% nanopropolis aktif sebagai antibakteri terhadap bakteri Escherichia coli.  Konsentrasi hambat tumbuh minimum  nanopropolis berada di bawah konsentrasi 0,02%. Ketika dibandingkan dengan sediaan tanpa teknologi nano (propolis biasa), pada kondisi konsentrasi sama nanopropolis lebih efektif daripada propolis biasa karena zona hambat yang dihasilkan lebih besar. Kata kunci  :  Trigona spp, propolis, dan teknologi nano
FORMULASI DAN UJI STABILITAS GRANUL EFERVESEN SARI BUAH SIRSAK (Annona muricata L.) Prasetyorini, -; Wiendarlina, Ike Yulia; Tiradisuci, Murni
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Publisher : Fakultas Matematika dan ilmu pengetahuan Alam. Universitas Pakuan.

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Abstract

This event will be based on research by the large number of reports on the benefits of soursop for various diseases especially antihipertensi and antihiperuresemia. Forms need to be developed so that a more practical preparations and ketersediannya continuous, one of which is in the form of effervescen granule juice. This research aims to find out whether the soursop fruit juice can be a formulation in granule material of efervesen who meet the requirements of quality, standards and terms of efervesen granule and making it acceptable in society. In the study of fruit juice made with the soursop fruit flesh filter using Batiste, juice drained using Freezedryer with the addition of maltodekstrin 20%. The powder is then made 3 fruit formula granule effervesent with the difference of acid-catalyzed and the manufacturing process is done by the method of smelting using alcohol 70% without binder. Test results show the BSLT fruit pollen have toxic effects against larvae of shrimp Artemiasalina Leach with LC50 108.914 ppm. The results of the evaluation of the third shows the formula for granule corner quietly and solubility are eligible, cohesive, and the granule flow values test froth above 70%, the test results of licentious formula2 has the most preferred taste. Stability test for efervesen granule 8 weeks the most stable at a temperature of 15 ° C containing Sodium ion levels 3, 97g/100 ggranul, potassium of 0, 24g/100 ggranul, 2, 19mg SAG polyphenols/ggranul and vitamins C51, 91mg/100ggranul. Key words : granul, efervesen, stabilitas, sirsak
Aktivitas Antibakteri Ekstrak Maserasi Bertingkat Bawang Dayak (Eleutherine palmifolia) terhadap Porphyromonas gingivalis dan Staphylococcus aureus Lusi Indriani; Prasetyorini Prasetyorini; Arfian Eka Saputri
MPI (Media Pharmaceutica Indonesiana) Vol. 2 No. 3 (2019): JUNE
Publisher : Fakultas Farmasi, Universitas Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (1913.485 KB) | DOI: 10.24123/mpi.v2i3.1316

Abstract

Bawang Dayak (Eleutherine palmifolia) dengan kandungan alkaloid, glikosida, flavonoid, fenolik, steroid, dan tanin, telah digunakan secara turun-temurun oleh suku Dayak sebagai obat tradisional. Secara empiris bawang Dayak berkhasiat sebagai diuretik, astringent, pencahar, analgesik, obat luka, batuk, sakit perut, disentri, kanker kolon, payudara, dan obat bisul. Porphyromonas gingivalis (bakteri gram negatif anaerob) dan Staphylococcus aureus (bakteri gram positif aerob) masing-masing merupakan bakteri yang menjadi penyebab periodontal dan infeksi kulit. Penelitian ini bertujuan untuk mengetahui aktivitas antibakteri ekstrak bawang Dayak hasil maserasi bertingkat terhadap P. gingivalis dan S. aureus. Bawang Dayak diekstraksi menggunakan metode maserasi bertingkat dengan pelarut n-heksan, etil asetat, dan etanol 70%. Masing-masing ekstrak ditentukan aktivitasnya dengan metode dilusi sehingga diperoleh nilai Konsentrasi Hambat Minimum (KHM). Ekstrak dengan nilai KHM terkecil kemudian ditentukan daya hambatnya terhadap kedua bakteri dengan metode difusi kertas cakram sehingga diperoleh nilai Lebar Daerah Hambat (LDH). Hasil penelitian menunjukkan bahwa ekstrak etil asetat memberikan daya hambat paling baik terhadap bakteri P. gingivalis yaitu dengan KHM 1,25%, sedangkan ekstrak etanol 70% dan ekstrak n-heksan masing-masing sebesar 2,5% dan 20%. Ekstrak etil asetat dan etanol 70% memberikan daya hambat yang sama terhadap bakteri S. aureus yaitu dengan KHM sebesar 5%. Daya hambat ekstrak etil asetat terhadap bakteri P. gingivalis dengan metode difusi tidak dapat ditentukan karena bakteri sulit ditumbuhkan. Daya hambat ekstrak etil asetat terhadap bakteri S. aureus lebih baik dibanding esktrak etanol 70%. Hal ini ditunjukkan dengan nilai LDH ekstrak etil asetat pada konsentrasi 20% adalah 9,21 mm, sedangkan ekstrak etanol 70% pada konsentrasi yang sama adalah 6,48 mm.
Critical Thinking Skills of Junior High School Students in Science Learning Yanih Maryani; Prasetyorini Prasetyorini; Irvan Permana
Scientiae Educatia: Jurnal Pendidikan Sains Vol 10, No 1 (2021): June 2021
Publisher : Tadris Biologi Fakultas Ilmu Tarbiyah dan Keguruan IAIN SYEKH NURJATI CIREBON

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24235/sc.educatia.v10i1.8034

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Critical thinking skills are part of the 21st-century skills that are important for students to have. Critical thinking skills as an asset for students to achieve success in life. The purpose of this study is to describe the critical thinking skills of a state junior high school student in Bogor in learning Science. This research is a qualitative descriptive study. The research sample was taken by purposive sampling on the seventh-grade students of a state junior high school in Bogor. The participants were 176 students consisting of 81 boys and 95 girls. The data were collected by giving a multiple-choice test with the open reason, which was developed based on the indicators of the critical thinking skills of Ennis and interviews with a science teacher. The data were processed using Microsoft Office Excel 2013, then analyzed descriptively and qualitatively. The data analysis resulted in as many as 1.70% of students being included in the critical category; 88.64% of students are in the less critical category, and 9.66% are in the far less critical category. It can be concluded that the critical thinking skills of seventh-grade junior high school students in Bogor are still low at an average of 53.07. This proves that students' critical thinking skills still need to be trained further so that they can be improved.
PROBLEM BASED LEARNING DENGAN STRATEGI MIND MAP PADA MATERI EKOSISTEM UNTUK MENINGKATKAN HASIL BELAJAR SISWA Ucun Radi Muharam; Prasetyorini .; Dadang Jaenudin
Jurnal Pendidikan dan Pengajaran Guru Sekolah Dasar (JPPGuseda) Vol 3, No 2 (2020): Jurnal Pendidikan dan Pengajaran Guru Sekolah Dasar (JPPGuseda)
Publisher : Universitas Pakuan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33751/jppguseda.v3i2.2547

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PROBLEM BASED LEARNING WITH A MIND MAP STRATEGY ON ECOSYSTEM MATERIALS TO IMPROVE STUDENT LEARNING OUTCOMESThis study aims to describe the improvement of student cognitive, affective and psychomotor learning outcomes in ecosystem material, teacher and student learning activities, and student responses in the learning process using the Problem Based Learning model with mind map strategies. The study was conducted at Cianjur District PGRI Pagelaran Junior High School. This study involved 29 students in the experimental class and 30 students in the control class. The research method used was quasi-experimental with only test post design design. Data collection techniques use multiple choice tests for cognitive learning outcomes, questionnaires for affective students care about the environment, and product evaluation and performance for psychomotor. The results of the study using the problem based learning model with mind map strategies can improve the cognitive learning outcomes of students with a significance value of 0,000 0,05, students' caring attitude towards the environment includes a good category with a percentage of 83%, student skills in making mind maps including medium and high with the percentage of 61% and 39% respectively, and student discussion skills included sufficient and good categories with a percentage of 33% and 67% respectively. Learning with problem based learning models with mind map strategies provides opportunities for students to find solutions to the problems given. Problem based learning with mind map strategies can improve student cognitive, affective and psychomotor learning outcomes.
Co-Authors - Affandi . Yulianita, . Ahmad Amirudin, Ahmad Alfi Syari Sukarya Anggita Rahmadini Anisa Bela Peron Arfian Eka Saputri Bina Lohita Sari Dadang Jaenudin Diah Mustikarini Dwi Ambarwati Eka Suhardi Fitri Laila Hariyanti Nenti Hasan, AE. Zainal Idah Paridah Ike Yulia Wiendarlina Indriyani Rachman Ismanto, - Ismi Senjayani Iyan Mulyana Kuntarti Suhartini Kurniasih Kurniasih Lusi Indriani Mira Miranti MOERFIAH . Novi Fajar Utami Novi Novitasari Rita Retnowati S. Kurniasih Siregar, Rofiqoh Sri Wardatun Suwary, Chrys Tiradisuci, Murni Ucun Radi Muharam Widoyanti, - Widya fitriyani Yanih Maryani