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Paediatrica Indonesiana
Published by Ikatan Dokter Anak Indonesia
ISSN : 00309311     EISSN : 2338476X     DOI : -
Core Subject : Health,
Health Professions Medicine & Pharmacology
Paediatrica Indonesiana is a medical journal devoted to the health, in a broad sense, affecting fetuses, infants, children, and adolescents, belonged to the Indonesian Pediatric Society. Its publications are directed to pediatricians and other medical practitioners or researchers at all levels of health practice throughout the world.
Arjuna Subject : -
Articles 2,118 Documents
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Risk factors of cerebral palsy in the perinatal period Santi Gunarwati; S. Yudha Patria; Madarina Julia
Paediatrica Indonesiana Vol 48 No 3 (2008): May 2008
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (175.704 KB) | DOI: 10.14238/pi48.3.2008.175-9

Abstract

Background Cerebral palsy is an irreversible yet preventablecondition, thus it is necessary to know the risk factors of thedisease. The potential risk factors that are found in the perinataland neonatal period i.e. asphyxia, sepsis, very low birth weight,premature birth, and neonatal seizure. No available data for therisk factors of cerebral palsy in Indonesia.Objective To identify the perinatal risk factors in cerebral palsy.Methods We performed an age and sex-matched nested case-control study. The case group was children with cerebral palsywho were born at Sardjito Hospital during 1997-2005. The controlgroup was selected from the same population as the case group.Risk factors during the perinatal period consisted of asphyxia,sepsis, very low birth weight, premature birth and neonatal seizure.Logistic regression was used to determine the association betweenrisk factors and cerebral palsy.Results Univariate analysis showed that the following factors wererisk factors for cerebral palsy, i.e., asphyxia (OR 5.6, 95%CI 2.48;12.53); premature birth (OR 4.5; 95%CI 1.55; 13.13); and neona-tal seizure (OR 7.5, 95%CI 3.13; 18.03). On multivariate analysisrisk factors associated with cerebral palsy were asphyxia (aOR6.3, 95%CI 2.42; 16.66) and neonatal seizure (aOR 10.9,95%CI4.03; 29.97).Conclusion Asphyxia and neonatal seizure are significant riskfactors of cerebral palsy in perinatal period
Linear growth patterns in small for gestational age and preterm infants after zinc supplementation Caecilia Nancy Setiawan; Gatot Irawan Sarosa; Mexitalia Setiawati
Paediatrica Indonesiana Vol 55 No 1 (2015): January 2015
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (196.635 KB) | DOI: 10.14238/pi55.1.2015.23-8

Abstract

Background Low birth weight (LBW) infants are at risk for growth disturbances due to intrauterine zinc deficiency. Zinc supplementation is expected to improve the linear growth of LBW babies. Objective To assess the effect of zinc supplementation on linear growth in preterm and small for gestational age (SGA) infants. Methods This quasi-experimental study had a pre- and post-test design. Subjects were LBW infants hospitalized in Kariadi Hospital during March-December 2011, consisted of SGA and preterm neonates. All subjects were given 5 mg of zinc syrup daily for 3 months. Subjects’ head circumference, weight, and length were measured monthly. Serum zinc levels were measured before and after supplementation. Data were analyzed with Chi-square test, independent T-test, and general linear model repeated measure. Results A total of 61 subjects were enrolled consisted of 31 preterm and 30 SGA neonates. Mean serum zinc levels in the preterm group were 168.2 (SD 54.5) μg/dL pre-supplementation and 163.6 (SD 50.7) μg/dL post-supplementation (P=0.049), while mean serum zinc levels in the SGA group were 174.8 (SD 46.6) μg/dL pre-supplementation and 167.4 (SD 49.4) μg/dL post-supplementation (P=0.271). Median percentage preterm weight and length increased from 87.3 to 102.4% in the third month (P<0.001) and from 95.8 to 103.9% in the third month (P<0.001), respectively. Median percentage SGA weight and length increased from 73.5 to 98.3% in the third month (P<0.001) and from 94.5 to 102.2% in the third month (P<0.001), respectively. Conclusion Both, the preterm and SGA infants exhibit catch-up growth after three months of zinc supplementation. [
The prevalence of insulin resistance in patients with β -thalassemia major at Cipto Mangunkusumo Hospital Caroline Mulawi; Bambang Tridjaja; Maria Abdulsalam; Zakiudin Munasir
Paediatrica Indonesiana Vol 43 No 4 (2003): July 2003
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (304.937 KB) | DOI: 10.14238/pi43.4.2003.117-20

Abstract

Background Diabetes mellitus is a common complication in pa-tients with thalassemia major. Iron overload plays an important roleby damaging the pancreatic β-cell and the liver cell, with the con-sequences of insulin deficiency and insulin resistance. Family his-tory of diabetes mellitus is one of the critical factors for the devel-opment of glucose metabolism derangement. However, the patho-genesis of glucose metabolism derangement remains unclear.Objective To evaluate the prevalence of impaired glucose toler-ance, diabetes mellitus, and insulin resistance in patients with β-thalassemia major treated in the Thalassemia Outpatient Clinic,Department of Child Health, Cipto Mangunkusumo Hospital,Jakarta.Methods This was a descriptive cross sectional study conductedin May 2002. Forty-eight subjects aged 10 to 18 years, grouped bytotal volume of transfusions and family history of diabetes mellitus,underwent an oral glucose tolerance test (OGTT), serum transfer-rin saturation, and insulin level examinations. Insulin resistancewas calculated from fasting plasma glucose and insulin concen-trations using the homeostasis model assessment (HOMA).Results One of 48 patients (2%) had impaired glucose toleranceat the age of 17 years. Diabetes mellitus occurred in three of 48patients (6%) at the age of 15.5 years in one patient and 18 yearsin two patients. Family history of diabetes mellitus was found in 2patients with diabetes mellitus and in the only one with impairedglucose tolerance. Insulin resistance was not detected in this study.Conclusion The prevalence of glucose metabolism derangementin patients with thalassemia major was low. No insulin resistancewas found in this study
Probiotic treatment in children with lactose intolerance – An open labeled the one group pre-test post-test experimental study Zainul Arifin; Aswitha D. Boediarso; Taralan Tambunan
Paediatrica Indonesiana Vol 46 No 3 (2006): May 2006
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14238/pi46.3.2006.139-43

Abstract

Background Lactose intolerance is the most common disorder ofintestinal carbohydrate digestion. Probiotic that contains the cor-rect strain in appropriate amount can be used as an alternativedietary for lactose intolerance patients.Objective This study was designed to describe the role of probioticin relieving lactose intolerance symptoms in children consumedfull-cream milk.Methods This study was a clinical trial. Inclusion criteria was chil-dren aged 12-14 years old, had a good nutrition and health status,with positive breath hydrogen test (BHT) result and lactose intoler-ance symptom(s), and their parents gave consent. Forty-two chil-dren were included. All subjects consumed one glass (200 ml) offull-cream milk twice a day for 21 days and recorded intolerancesymptoms. Probiotic was added from 8 th to 21 st day in their milk,and responses of treatment were evaluated by scoring system(based on borborigmic, flatulence, abdominal bloating, nausea andvomiting, abdominal pain, and diarrhea symptoms). At the end ofstudy they were undergone second BHT examination.Results There were decreasing mean score rates at 7 th day (pre)13.8 (SD 5.5) compared with 7.5 (SD 3.5) at 14 th day (after) andwas statistically significant (P<0.001). Mean score rate at 7 th day(pre) 13.8 (SD 5.5) compared with 21 st day (after) was 0.119 (SD0.55) and was statistically significant (P<0.001). At the end of study,only 2 subjects showed clinical signs of lactose intolerance. Thirty-six subjects had normal BHT result at 21 st day and was statisti-cally significant (P<0.001).Conclusion Two weeks administration of probiotic could relievelactose intolerance symptoms in children consumed full-cream milk
Hypertension due to renal artery stenosis Husein Albar; Haeriah Rahman; Syarifuddin Rauf
Paediatrica Indonesiana Vol 41 No 1-2 (2001): January 2001
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (413.376 KB) | DOI: 10.14238/pi41.1.2001.60-3

Abstract

A case of a 12-year-old boy with renal artery stenosis as a cause of hypertension is presented. The diagnosis of renal artery stenosis was established based on the bruit heard over costovertebral angle and the increased plasma rennin secretion, and further confirmed by angiogram finding. The detection of bruit, either on the abdomen or costovertebral angle, in association Indones with hypertension should initially lead to the consideration of the presence of renal artery stenosis.
The Preschool Child in Suka_ Village, North Sumatra III. Upper arm Circumference and Skinfolds as Indicators of Nutritional Status Jane A. Kusin; H. S. R. Parlindungan Sinaga; J. Khoman; J. M. Houtkooper; U. Renqvist
Paediatrica Indonesiana Vol 22 No 1-2 (1982): January - February 1982
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14238/pi22.1-2.1982.1-10

Abstract

Upper arm circumfereru:e, triceps and subscapular skinfolds were measured at 6-monthly intervals during one year in a group of preschool children, age 0 - 5 years.All 3 measurements decreased as compared with the reference in the age period 1 - 23 months followed by a catch-up at age 2- 4 years.The predictive value of upper arm circumference for the development af malnutrition was low. Age group 1 - 23 months should be considered "at risk" irrespectively of the nutritional state at the time of examination.Absence of mortality may be attributed to the fact that children can eat to appetite, when they are healthy and to the simple medical treatment given.
Juvenile myasthenia gravis Prastiya I. Gunawan; Darto Saharso
Paediatrica Indonesiana Vol 47 No 5 (2007): September 2007
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (302.484 KB) | DOI: 10.14238/pi47.5.2007.244-6

Abstract

Transcatheter closure of tubular type patent ductus arteriosus using Amplatzer® ductal occluder II: a case report Mulyadi M Djer; Nikmah Salamia Idris; Angelina Angelina
Paediatrica Indonesiana Vol 53 No 5 (2013): September 2013
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (467.951 KB) | DOI: 10.14238/pi53.5.2013.291-4

Abstract

Patent ductus arteriosus (PDA) is a common congenital heart disease, accounting for 5-10% of all congenital heart diseases. The incidence of PDA is even higher in preterm neonates, ranging from 20-60%.1-4 Closure of PDA is indicated in all cases, except for duct-dependent congenital heart diseases or PDA with Eisenmenger syndrome.1,5,6 In small asymptomatic PDAs, closure is indicated to prevent the risk of complications, such as endarteritis, endocarditis, aneurysm of ductus arteriosus, or congestive heart failure.1,2,7In recent years, interventional cardiology has become a gold standard therapy for the majority of PDA cases beyond neonatal age. Since its introduction in 1967, many devices and methods have been developed to allow transcatheter closure of virtually all PDAs, regardless of size or configuration. Nevertheless, the tubular shape (type C) PDA, which has the highest residual shunt rate, still poses a great challenge for the interventionist.8-10 The second generation of Amplatzer® device occluders (ADO II), released in 2007, has been suggested to be effective in closing tubular PDAs.10 The purpose of this study was to report the initial clinical experience using ADO II to close a tubular type PDA in Indonesia.
Obesity in children with frequent relapse and steroid dependent nephrotic syndrome Jeanne Vidianty; Sudung O. Pardede; Aryono Hendarto; Arwin A. P. Akib
Paediatrica Indonesiana Vol 50 No 3 (2010): May 2010
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14238/pi50.3.2010.139-43

Abstract

Background Children \\lith frequent relapse and steroid dependent nephrotic syndrome (FRNS/SDNS) will experience frequent relapse v.ith many complications due to the disease and toxicity of steroid therapy. One of the most common complications is obesity which is associated \\lith significant health problems in childhood and important risk factor of adult morbidity and mortality. Objective To find out the prevalence of obesity in children 'With FRNS/SDNS.Methods A cross sectional study was conducted from November 2008 until March 2009. Data were collected from the medical records of children 'With FRNS/SDNS treated during the period of 2000-2008. Body weight, height and body fat mass measurement was performed on the subjects. The diagnosis of obesity was based on body mass index (BMI) and body fat mass measurement.Results Obesity was diagnosed in 10 of 43 children (23%). Most of them were 5􀀼9 years old (58%) 'With male􀀼predominance. Most patients (70%) had age of onset younger than 5 years. The median of total relapse was 7 (range 2􀀼24) and cumulative dose of prednisone was 12,240 (range 3,490 to 44,330) mg. Time since the last dose of prednisone until the study in majority was 0 to 6 months (53%). The prevalence of obesity based on BMI was 7%while based on body fat mass was 23 (el 95% 10 to 36) %. Conclusion The prevalence of obesity based on body fat mass was 23%. The median BMI of obese subjects is in the 90-95th percentile. 
Diabetic ketoacidosis with acute kidney injury in prepubertal children: a report on two cases Dwi Andriyani; Afriyan Wahyudhi; Shirley Leonita Anggriawan
Paediatrica Indonesiana Vol 56 No 6 (2016): November 2016
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (750.056 KB) | DOI: 10.14238/pi56.6.2016.360-8

Abstract

Type 1 diabetes mellitus is a result of autoimmune damage, in which environmental factors are thought to trigger the autoimmune destruction of pancreatic ß-cells.1,2 Worldwide, an estimated 65,000 children under 15 years of age develop type 1 diabetes mellitus each year.3 Approximately 30% of children who present with newly-diagnosed type 1 diabetes have diabetic ketoacidosis (DKA).4 Himawan et al. reported a DKA prevalence of43.6% in girls.5 The long-term effects of diabetes mellitus include retinopathy, chronic kidney disease (nephropathy), neuropathy, and dyslipidemia.2

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