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BIOLINK (Jurnal Biologi Lingkungan, Industri, Kesehatan)
Published by Universitas Medan Area
ISSN : 25975269     EISSN : 2356458X     DOI : 10.31289
Biolink focuses on the publication of the results of scientific research related to fields. This article is published in the internal and external academic community of the University of Medan Area (UMA) especially in the field of Biology. Biolink publishes scientific articles in the scope of biology that includes environmental biology, industrial biology and health biology. Published articles are the results of research articles, studies or critical and comprehensive scientific studies on important issues related to the field of biology.
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Articles 378 Documents
CORRELATION BETWEEN ADHERENCE OF ANTIHYPERTENSIVE DRUGS USE AND BLOOD PRESSURE CONTROL IN PATIENTS WITH ESRD UNDERGOING HEMODIALYSIS Tedy Kurniawan Bakri; Raihanul Akmal; Azizah Vonna; Lydia Septa Desiyana; Fitrah Sari
BIOLINK (Jurnal Biologi Lingkungan Industri Kesehatan) Vol 8, No 2 (2022): Februari 2022
Publisher : Universitas Medan Area

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31289/biolink.v8i2.6028

Abstract

Antihypertensive therapy used in patients with End-Stage Renal Disease undergoing hemodialysis is objected to decrease mortality related to ESRD complications. Nonadherence to antihypertensive therapy can lead to uncontrolled blood pressure. This study aims to determine the level of adherence to antihypertensive drugs and its correlation to blood pressure control in ESRD patients undergoing hemodialysis. It was an observational analytic study based on the cross-sectional method. Sixty  person subjects were involved using the quota sampling technique. The level of adherence was examined using the Modified Morisky Scale questionnaire. Blood pressure data were obtained from mean values of respectively pre, during, and post-hemodialysis blood pressure within four hemodialysis visitations. The data was examined bivariately using the Chi-square test with a 95% confidence interval. The results show most patients have high level of adherence to antihypertensive treatments (55%) yet have uncontrolled levels of blood pressure (95%). The Chi-square analysis found there is no significant relationship between the level of adherence to antihypertensive therapy and the average blood pressure level of ESRD patients who undergo hemodialysis (p-value 0,301). This finding suggests a consideration in monitoring the effectivity of hypertension management that adherence is not a single significant factor affecting the successfulness of medication.
ENVIRONMENTAL IMPACT OF CEMENT PRODUCTION ACTIVITIES IN BOOLANG REGENCY, MONGONDOW, NORTH SULAWESI Ilham Akbar Mustafa; Hayati Sari Hasibuan; Ahyahudin Sodri
BIOLINK (Jurnal Biologi Lingkungan Industri Kesehatan) Vol 8, No 2 (2022): Februari 2022
Publisher : Universitas Medan Area

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31289/biolink.v8i2.5138

Abstract

The cement industry is a large industry that can have an impact on the surrounding environment. In the area of Boolang Regency, Mongondow, North Sulawesi, there is a foreign cement industry that has only been operating for about 2 years. Therefore, it is necessary to study the environmental impacts that have occurred around the cement industry. The objective of this study is to analyze the impact of the physical environment, especially water, on the production activities of the cement industry in Boolang Regency, Mongondow, North Sulawesi. The research method used was a laboratory test and the data were processed using STORET. The results showed that the water quality in the residents' wells was in very good condition, while the surface quality of the river water around the cement industry area could be categorized as lightly polluted.
THE REMOVAL EFFICIENCY OF ORGANIC LOADING, PHOSPHATES AND DETERGENTS IN WASTEWATER OF CAR WASH SERVICE BY CONSTRUCTED WETLAND SYSTEM Theofilus Stm; Haryati Bawole Sutanto; Guruh Prihatmo
BIOLINK (Jurnal Biologi Lingkungan Industri Kesehatan) Vol 8, No 2 (2022): Februari 2022
Publisher : Universitas Medan Area

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31289/biolink.v8i2.5796

Abstract

The car wash wastewater has a proportion of detergent  and it can cause considerable impacts to pollute the environment and health if they are not processed in well. SSVF CW is one of  an alternative wastewater treatment, because it has the advantage such as wastewater flowing below the surface of the media so it  reduces the smell of wastewater. The objective of this study was to determine the  removal efficiency of reducing pollutants in the wastewater of treated car wash by Constructed Wetland and the influence of Chrysopogon zizanioides rhizosphere depth in supplying DO distribution. This experimental laboratory scale study used 2 PVC for reactor. Each pipe has 4 sampling points. The DO was measured from different depth, while the other parameters were from the effluent. The ratio of the media used was  1:3:2:4 from the top to the bottom. The SSVF CW system had high TSS removal efficiency of 94.74%, while the removal efficiency of COD, Detergent, and Phosphate was76.21%, 54.54%, 30.65%, respectively. DO distribution at a depth of 84 cm in both pipes increased even though the root zone was only 26.5 cm.  
THE EFFECT OF KESAMBI BARK EXTRACT ON MICE LYMPHOCYTE COUNT AND SPLEEN INDEX Christine Stefani Tamelan; Kukuh Madyaningrana; Vinsa Cantya Prakasita
BIOLINK (Jurnal Biologi Lingkungan Industri Kesehatan) Vol 8, No 2 (2022): Februari 2022
Publisher : Universitas Medan Area

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31289/biolink.v8i2.6039

Abstract

Kesambi is a plant widely used by people of Timor Island. Flavonoid content of Kesambi is potential to be used as immunomodulators. This study aimed  to study the effect of Kesambi bark extract on lymphocyte count and spleen index of male mice as an indicator of their immune responses. Research included identification of phytochemical compounds macerated from Kesambi bark, lymphocytes count and spleen index calculation. Mice injected with sheep erythrocytes were treated orally with three doses of Kesambi extract (0.113 mg/g BW, 0.491 mg/g BW, and 0.712 mg/g BW) for 10 days. Lymphocyte count using blood smear method was carried out on day 0, 5 and 10, while lymphocyte count using hematology analyzer and spleen index measurement were performed after mice sacrificed. Kesambi bark contains alkaloids, flavonoids, tannins, and steroids. Treatment with Kesambi bark extract reduced mice lymphocyte count. Administration of 0.491 mg/gr BW dose reduced the mice lymphocytes count close to the number of lymphocytes in the negative control group. The spleen index of mice had no correlation with changes in the number of lymphocytes. This preliminary study shows a potential use of Kesambi bark extract as a natural immunosuppressant.
EFFECT OF PERIWINKLE (CATHARANTHUS ROSEUS) LEAF EXTRACT ON LIVER HISTOLOGY OF MICE (MUS MUSCULUS L) AFTER ASPARTAME INDUCE Mahriani Mahriani; Rosita Dewi Wulandari; Susantin Fajariyah
BIOLINK (Jurnal Biologi Lingkungan Industri Kesehatan) Vol 8, No 2 (2022): Februari 2022
Publisher : Universitas Medan Area

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31289/biolink.v8i2.5161

Abstract

Aspartame is an artificial sweetener in foods and beverages. Continuous use of aspartame will result in oxidative stress in the liver. So we need antioxidants from outside the body such as periwinkle leaves.This study aims to determine the effect of periwinkle leaves (Catharanthus roseus L) on aspartame-induced liver histology. This study used 24 male mice divided into 4 groups, namely negative control (K-) without treatment; Positive control (K +) treatment of aspartame; D1: treatment of aspartame and periwinkle extract doses of 0.42 mg/kg. D2: aspartame and periwinkle  extract doses of 0.84 mg/kgbb. Administration of aspartame dose of 0.2 mg /kgbb by intraperitoneal  for 14 days followed by gavage administration of periwinkle leaf extract for 12 days. The liver was taken on the 27th day by surgery, then made slide histology with Hematoxylin-Eosin staining. The results show that the administration of Catharanthus roseus leaf extract at a dose of 0.84 mg/kgbw in aspartame-induced mice was effective in reducing hepatocyte damage, namely hydrophilic degeneration and necrosis.
ANALYSIS OF LEAD CONTENT (Pb) IN WASTE STREAMS AND WELL WATER AND PUBLIC HEALTH COMPLAINTS AROUND THE PAPER INDUSTRY IN BONDOWOSO Balgis Putri Salindra; Prehatin Trirahayu Ningrum; Yunus Ariyanto
BIOLINK (Jurnal Biologi Lingkungan Industri Kesehatan) Vol 8, No 2 (2022): Februari 2022
Publisher : Universitas Medan Area

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31289/biolink.v8i2.5619

Abstract

Wastewater in an industry which is often called liquid waste is a by-product produced by several human activities. Liquid waste pollution from industrial effluents containing lead (Pb) in dug well water used by the community for daily needs can cause poisoning and health complaints. This study aims to determine the content of lead (Pb) in the liquid waste stream and well water as well as public health complaints around the pulp and paper industry. This type of research was descriptive with the observational method. Liquid waste from the paper and pulp industry is known to contain heavy metal type lead (Pb), if it pollutes the environment around the industry it can cause various negative impacts for the community. There were 2 samples of dug well water 90 meters that have lead content above the quality standard, namely in well 8 and well 10 with lead content of 2,998 mg/L and 4,247 mg/L while for other dug well water it did not exceed the threshold value with results below 0.0085 mg/L. Based on the results of interviews with 40 respondents, most of the respondents who used dug well 8 and well 10 water experienced health complaints such as skin redness and itching on the hands and arms, and the most experienced redness, itching, and hot eyes after using dug well water contaminated with lead (Pb).
MACROZOOBENTHOS DIVERSITY AND FUNCTIONAL FEEDING GROUP (FFG) IN BEREMBANG RIVER OF WEST KALIMANTAN Wolly Candramila; Sisi Marda Lorensa; Yunike Pristalika; Junardi Junardi
BIOLINK (Jurnal Biologi Lingkungan Industri Kesehatan) Vol 8, No 2 (2022): Februari 2022
Publisher : Universitas Medan Area

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31289/biolink.v8i2.6131

Abstract

This study analyzes macrozoobenthos diversity and functional feeding group in Berembang River, Kubu Raya Regency, West Kalimantan. The obtained macrozoobenthos were identified to the genus level, and their functional feeding group was determined through a literature study. Data on diversity, evenness, and dominance were analyzed descriptively. Diversity (H') and Evenness (E) of macrozoobenthos in Berembang River were low (H'=0.73 and E=0.15) while Dominance (C) was high (C=0.81) as evidenced by a large number of genera Corbicula and Gammarus. Macrozoobenthos functional feeding groups found at both stations can be divided into six categories, namely shredders, gathering collectors, deposit feeders, sub-surface deposit feeders, filtering collectors, and scrapers.
BIOECOLOGY OF GIANT FRESHWATER PRAWNS (MACROBRACHIUM ROSENBERGII) IN THE BILAH RIVER, LABUHANBATU DISTRICT, NORTH SUMATERA Siti Aminah Nasution; Rivo Hasper Dimenta
BIOLINK (Jurnal Biologi Lingkungan Industri Kesehatan) Vol 8, No 2 (2022): Februari 2022
Publisher : Universitas Medan Area

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31289/biolink.v8i2.5191

Abstract

Giant freshwater prawns (Macrobrachium rossenbergii) were still been the favorite prawn catch of local fishermen in the Labuhanbatu district. This raises concerns for the survival of these animals. Therefore, it is necessary to conduct a study to obtain bioecological information on this giant freshwater, giant prawns in the Bilah river especially inform about condition the abundance based on gonad maturity levels, and the growth patterns of Giant freshwater prawns (M. rossenbergii). This study was conducted at 3 stations around the Bilah river. These stations were determined using a purposive sampling method. Furthermore, sampling was carried out using fishing nets. After that, the caught fish were analyzed to find out the Fulton’s condition factor, the abundance of prawns based on gonad maturity levels, and the growth patterns. The results of growth patterns analysis which calculate from the relationship of carapace length and body weight of M. rossenbergii caught were showed negative allometric category (b value 1.88 to 2.577). Meanwhile, the abundance of giant freshwater prawns based on gonad maturity levels for males and females were dominated by immature prawns (ranging from 46.15 to 54.65%).
ISOLATION, IDENTIFICATION, AND METAL RESISTANCE TESTING OF SOIL FUNGI (RHIZOSPHERE) FROM BANGKA TIN POST-MINING Mutiara Darlingga; Rahmad Lingga; Andri Kurniawan
BIOLINK (Jurnal Biologi Lingkungan Industri Kesehatan) Vol 8, No 2 (2022): Februari 2022
Publisher : Universitas Medan Area

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31289/biolink.v8i2.5512

Abstract

The ecological impacts of tin mining activities in the Bangka island is the presence of heavy metal contamination that accumulated in the environment. One of the heavy metals that was often found in post-tin mining areas is lead (Pb). Mycoremediation is a method that can be used to reduce lead pollution in post-tin mining areas. This study aimedto isolate, resistance test and identify to Pb-resistant soil fungi (rhizosphere) in the post-tin area of Bangka. The research methods included isolation, test of fungal resistance to Pb metal (Control, 150ppm, 250ppm, 350ppm, 500ppm, 1,000ppm, 5,000ppm and 10,000ppm), macroscopic and microscopic identification. The results showed that 9 isolates tested, there were 6 isolates that were resistant to Pb up to the concentration of 5,000 ppm, namely isolates I1(Rhizoctonia), I2(Penicilllium sp1), I5(Papulaspora), I6(Penicillium sp2), I7(Penicillium sp3) and I9 (Sclerotium). Three isolates of soil fungus were not resistant to Pb up to a concentration of 5,000 ppm, namely isolates I4 (Sclerotium), I8(Microsporum), and I10(Cladosporium). All isolates did not grow anymore at a concentration of 10,000 ppm of Pb.
THE EFFECT OF PASTEURIZATION STAGE ON THE PRODUCTION OF STRAW MUSHROOM (VOLVARIELLA VOLVACEA, BULL. EX. FR./SING.) Jessica Elfani Bermuli; Wahyu Irawati; Reisky Megawati Tammu
BIOLINK (Jurnal Biologi Lingkungan Industri Kesehatan) Vol 8, No 2 (2022): Februari 2022
Publisher : Universitas Medan Area

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31289/biolink.v8i2.6167

Abstract

God created Indonesia with a tropical climate that is very appropriate to support the development of straw mushroom cultivation (Volvariella volvaceae). One of the stages of mushroom cultivation sequentially is pasteurization. This study aims to determine the effect of pasteurization stages, the accuracy of the pasteurization temperature, and the factors that influence the growth of straw mushrooms. The method in this study was carried out using livestock manure, with a composition of 400 gr goat manure and 500 gr rabbit manure. The pasteurization stage is maintained at a temperature of 60-700C with a humidity of 80-90%. The watering interval at the observation stage was 4 days with a frequency of 40% in experiment 1 and every day or a frequency of 100% in experiment 2. The results showed that the pasteurization stage was very influential on the mushroom growing media. Inaccuracy in pasteurization resulted in many weeds that thrived, thus inhibiting the growth of straw mushrooms. The optimal temperature in the pasteurization stage is 60-900C. The factors that influence the growth of mushroom are the selection of materials as fertilizers for mushroom cultivation, temperature, humidity include interval and frequency of watering, pasteurization process, weeding the contaminants, and time of observation.