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Jurnal Profesi Medika: Jurnal Kedokteran dan Kesehatan
Published by Universitas Pembangunan Nasional Veteran Jakarta
ISSN : 02163438     EISSN : 26211122     DOI : -
Core Subject : Health,
Health Professions Medicine & Pharmacology
Arjuna Subject : -
Articles 244 Documents
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The Relationship Between Personal Hygiene and The Prevalence of Tinea Unguium Infection Among Farmers in Jember District Mufida, Diana Chusna; Himma, Alyatul; Agustina, Dini; Armiyanti, Yunita; Sofiana, Kristianningrum Dian
Jurnal Profesi Medika : Jurnal Kedokteran dan Kesehatan Vol 18 No 1 (2024): Jurnal Profesi Medika : Jurnal Kedokteran dan Kesehatan
Publisher : Fakultas Kedokteran UPN Veteran Jakarta Kerja Sama KNPT

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33533/jpm.v18i1.7514

Abstract

Tinea unguium is an infection of the nail caused by dermatophyte fungi. Nails infected with the fungus will be discolored, thick, and brittle. Personal hygiene is one of the risk factors that can affect tinea unguium. This study aimed to determine the relationship of personal hygiene to the prevalence of tinea unguium infection in farmers in the Jember Regency. The benefits of research can be used as a source of information about the importance of maintaining personal hygiene to avoid fungal infections that cause tinea unguium. This study used an analytic observational method with a cross-sectional approach. This research was conducted from August to December 2023 in 10 districts of Jember Regency. The population in this study were all farmers in Jember Regency. The sample in this study was calculated by the Slovin formula and obtained from as many as 100 farmers who met the inclusion and exclusion criteria. Sampling using mixed methods sampling. The statistical analysis used is Cramer's V test α = 0.05. The results of this study show a significant relationship between personal hygiene and the prevalence of tinea unguium in farmers in Jember Regency with a p-value of 0.004 (0,004<0,05).
Hormonal and Laboratory Profile of Polycystic Ovarian Syndrome (Pcos) Women Visiting Fertility Center in Indonesia Sundari, Ayu Mulia; Wulandari, Tri Aprilliana; Prakoso, Nurul Muhammad; Dwiranti, Astari; Abinawanto; Boediono, Arief; Funahashi, Hiroaki; Bowolaksono, Anom
Jurnal Profesi Medika : Jurnal Kedokteran dan Kesehatan Vol 18 No 1 (2024): Jurnal Profesi Medika : Jurnal Kedokteran dan Kesehatan
Publisher : Fakultas Kedokteran UPN Veteran Jakarta Kerja Sama KNPT

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33533/jpm.v18i1.7546

Abstract

Our study aims to scrutinize the hormonal and laboratory profile of women with PCOS visiting a fertility center in Indonesia. A computerized database of 120 PCOS women and 120 controls was retrospectively reviewed and analyzed. According to analysis, the concentration of AMH and basal LH were significantly more elevated in the PCOS group than in the control group (6.77 vs. 2.05, P<0.001; and 6.8 vs. 5.3, P<0.001, respectively). The level of basal FSH was significantly lower in the PCOS group (5.83 vs. 7.86; P<0.001). After an IVF cycle, PCOS women had significantly higher retrieved oocytes and mature oocytes compared to controls (18 vs. 8, P<0.001; 12 vs. 6, P<0.001). The number of fertilizations, cleavages, and top-quality cleavages were also higher in the PCOS group than in the control group (10 vs. 4, P<0.001; 10 vs. 4, P<0.001; 4 vs. 2, P<0.001). At the blastocyst stage, patients with PCOS had a higher number of blastocysts and top-quality blastocysts than control (9 vs. 4, P<0.001); 4 vs. 1, P<0.01). However, the clinical pregnancy was significantly higher in the control group than in the PCOS group (52.6% vs. 16.7%; P = 0.045).
Chronic Septic Granulomatosis Revealed in Adulthood by Respiratory Manifestations Haouassia, Fatima Ezzahra; Chaanoun, Khadija; Zaghba, Nahid; Benjelloun, Hanane; Yassine, Najiba
Jurnal Profesi Medika : Jurnal Kedokteran dan Kesehatan Vol 18 No 1 (2024): Jurnal Profesi Medika : Jurnal Kedokteran dan Kesehatan
Publisher : Fakultas Kedokteran UPN Veteran Jakarta Kerja Sama KNPT

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33533/jpm.v18i1.7554

Abstract

Chronic septic granulomatosis is a rare genetic disease that affects the immune system. It is characterized by a primary immune deficiency that makes it more difficult for phagocytic cells (such as polymorphonuclear neutrophils, eosinophils, monocytes, and macrophages) to eradicate some harmful bacteria and fungi. It is considered an orphan disease because it affects less than 0.05% of a given population.
Clinical Characteristics of Children with Refrative Amblyopia at Cipto Mangunkusumo National Referral Hospital Yulia, Dian Estu; Barliana, Julie Dewi; Sitorus, Rita Sita; Putri, Meuthia Rana; Soeharto, Diajeng Ayesha
Jurnal Profesi Medika : Jurnal Kedokteran dan Kesehatan Vol 18 No 1 (2024): Jurnal Profesi Medika : Jurnal Kedokteran dan Kesehatan
Publisher : Fakultas Kedokteran UPN Veteran Jakarta Kerja Sama KNPT

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33533/jpm.v18i1.7582

Abstract

Amblyopia, commonly referred to as 'lazy eye’, manifests as a reduction in best corrected visual acuity (BCVA) in the absence of detectable ocular structural abnormalities. Refractive amblyopia specifically denotes a subtype of amblyopia arising from uncorrected refractive errors. A retrospective descriptive analysis was conducted on medical records of all pediatric patients with refractive amblyopia at the Department of Ophthalmology, Cipto Mangunkusumo Kirana National Referral Hospital, Jakarta, Indonesia in 2018 to 2022. A total of 391 eyes of 224 patients were included. Median age was 8 (5-18) years, with majority being older than 7 years of age (58.7%). Leading method of treatment was with spectacles alone (80.4%). Overall amblyopia improvement was mostly observed after six months of treatment. In conclusion, refractive amblyopia at our hospital was highly prevalent among children. Thus, early detection and treatment of refractive errors in children is essential to prevent refractive amblyopia.
Determination of Complete Blood Count Reference Values of Mindray BC-760 Hematology Analyzer Iriani, Anggraini; Armenia, Dhinasty; Putri, Dian Eka; Shafwandi, Ritki Fazapadena; Murdianto, Rendy; Aditya, Legina; Purnamasari, Endah; Bahri, Syukrini; Aprilio, Henri; Poerwantoro, Bambang
Jurnal Profesi Medika : Jurnal Kedokteran dan Kesehatan Vol 18 No 1 (2024): Jurnal Profesi Medika : Jurnal Kedokteran dan Kesehatan
Publisher : Fakultas Kedokteran UPN Veteran Jakarta Kerja Sama KNPT

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33533/jpm.v18i1.7644

Abstract

Hematological assessment serves as a standard examination in supporting diagnostics in clinical practice. The advanced hematology analyzer instrument namely Mindray BC 760 has recently introduced several new hematological parameters which previously unavailable. This study set out to establish the value of the reference interval of those new parameters on the Mindray BC 760 device in the Indonesian adult population. This observational study took place at Yarsi Hospital, Jakarta from March to August 2023. A total of 352 subjects who underwent medical check-ups at pathology clinics laboratory in the hospital were enrolled. All participants comprised both females and males aged > 17 years and were confirmed to be healthy through examination. Hematological assessment using Mindray BC 760 device. A remarkable significant difference was observed between females and males (p< 0.05) in terms of Hb, RBC, MCH, MCHC, RHE, RET, PLT, PDW, PCT, PLCC, Monocyte and eosinophil count, and neutrophil%. Conversely, MCV, RDW-SD, RET%, IRF, LFR, MFR, HFR, NRBC, NRBC%, WBC, NEU, LYM, BAS, IMG, LYM%, BAS%, IMG%, MPV, IPF showed no significant differences based on gender. It is recommended to adjust of reference interval value according to gender for several novel hematological parameters assessed through the Mindray BC 760 instrument.
Testing The Antibacterial Effectiveness of Black Cumin Extract on The Growth of Bacteria Bacillus Cereus Disk Diffusion Method Yuliati, Yuliati
Jurnal Profesi Medika : Jurnal Kedokteran dan Kesehatan Vol 18 No 1 (2024): Jurnal Profesi Medika : Jurnal Kedokteran dan Kesehatan
Publisher : Fakultas Kedokteran UPN Veteran Jakarta Kerja Sama KNPT

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33533/jpm.v18i1.7682

Abstract

The main components of volatile oils are thymoquinone, thymohydroquinone, thymoquinone, thymol, and tannin which have been proven to be able to inhibit bacterial growth. This research was conducted to determine the antibacterial effectiveness of black cumin against the growth of Bacillus cereus bacteria with various concentrations of 10%, 25%, 50%, 75%, and 100% using the diffusion method. The type of research used by researchers is experimental. In this study, the disk disc method was used with concentrations of 10% 25%, 50%, 75%, and 100% using Amoxicillin 0.3% as a positive control for Bacillus cereus bacteria with repetition three times, by soaking the disc for 15 minutes in each concentration and attach the disc to media that has been inoculated with Bacillus cereus bacteria. Based on research results from the results of measurements of the inhibitory zone of the Bacillus cereus bacterium, it is included in the weak category with all concentrations showing an inhibitory zone with an average diameter of 8.67 mm, 10.67 mm, 12 mm, 16.33 mm, and 17.67 mmm. The conclusion from research on the antibacterial effectiveness of black cumin extract can inhibit the growth of Bacillus cereus bacteria in the weak inhibition category.
Potential of Rambutan-Honey Antioxidants in Reducing Malondialdehyde Levels and Regenerating Hepatocyte Cells in Isoniazid-Rats Induced Yuslianti, Euis Reni; Ratwita, Welly; Koswara, Teja; Afra, Aldilla
Jurnal Profesi Medika : Jurnal Kedokteran dan Kesehatan Vol 18 No 1 (2024): Jurnal Profesi Medika : Jurnal Kedokteran dan Kesehatan
Publisher : Fakultas Kedokteran UPN Veteran Jakarta Kerja Sama KNPT

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33533/jpm.v18i1.7713

Abstract

Hepatotoxicity induced by prolonged administration of antituberculosis drugs such as isoniazid (INH) is associated with the production of free radicals. Rambutan-honey, rich in catalase enzyme, flavonoids, and vitamin C, exhibits antioxidant and immunomodulatory properties. This study purpose to assess the effect of rambutan-honey on malondialdehyde (MDA) levels and hepatocyte cell numbers in INH-induced rats. The research method using in vivo experimental study with a randomized posttest-only control group design. Thirty Wistar rats were divided into five groups: negative control(G1), positive control(G2), and three groups treated with rambutan-honey at doses of 250 mg/kgBW(G3), 500 mg/kgBW(G4), and 1000 mg/kgBW(G5). MDA levels were measured using the TBARS method on days 15 and 23, while hepatocyte cell numbers were assessed through histopathological examination using Hematoxylin-Eosin. Data were analyzed using One-Way ANOVA followed by Post-Hoc test. This study revealed that rambutan-honey at doses of 250, 500, and 1000 mg/kgBW significantly reduced MDA levels compared to controls, with a simultaneous increase in hepatocyte cell numbers (p=0.001). The conclusion of this research is the potential of rambutan-honey as an antioxidant and hepatoprotective agent, possibly mediated by its flavonoid content, which may stimulate superoxide dismutase activity akin to catalase enzyme and vitamin C.
The Comparison of Surface Dose in Vivo Dosimetry Using 3D-CRT and IMRT Technique on Breast Cancer Case Wulandari, Sri; Ulya, Syarifatul; Diyona, Fiqi; Adrial, Rico; Prasetio, Heru
Jurnal Profesi Medika : Jurnal Kedokteran dan Kesehatan Vol 18 No 1 (2024): Jurnal Profesi Medika : Jurnal Kedokteran dan Kesehatan
Publisher : Fakultas Kedokteran UPN Veteran Jakarta Kerja Sama KNPT

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33533/jpm.v18i1.7771

Abstract

The aim of this study is to verify the adequacy of the surface radiation dose calculated by the Treatment Planning System (TPS) using 3DCRT and IMRT technique with the dose measured by the TLD-100, referring to the report of the American Association of Physicists in Medicine Task Group No.219 (AAPM-TG No.219). This research process began with annealing the TLD-100 at the Research Center for Safety Technology Metrology and Nuclear Quality of the National Innovation Research Agency (PRTKMMR-BRIN), followed by scanning the TLD-100 on the surface of the phantom plate using a CT simulator. In addition, the TLD-100 was calibrated with different radiation doses (0; 20; 50; 80; 100; 150; 200; 250; 370) cGy. Verification of the surface radiation dose was performed by calculating the TPS surface dose by Patient Specific Quality Assurance (PSQA) and comparing it with the dose measured by the TLD-100. The result is Radiation techniques such as IMRT are more conformal than 3D-CRT because they precisely control dose intensity, making the TLD dose in IMRT closer to TPS. Differences in detector types such as TLD also affect the results of radiation dose measurements. Continuous assessment of patient dose is important for the safety of radiation therapy.
Impact of Age Initiation and Duration of Hemodialysis on Impaired Cognitive Function Experienced by Chronic Kidney Disease (CKD) Patients Nindela, Rini; Prastowo, Sigit Nur; Zulissetiana, Eka Febri; Marisdina, Selly; Fazzaura Putri, Siti Sarahdeaz
Jurnal Profesi Medika : Jurnal Kedokteran dan Kesehatan Vol 18 No 1 (2024): Jurnal Profesi Medika : Jurnal Kedokteran dan Kesehatan
Publisher : Fakultas Kedokteran UPN Veteran Jakarta Kerja Sama KNPT

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33533/jpm.v18i1.7830

Abstract

The prevalence of people with chronic kidney disease (CKD) in Indonesia increases with age. Various complications to death can occur in CKD patients, one of which is impaired cognitive function. In addition, end-stage CKD treatment options, such as hemodialysis, further increase the risk of complications of cognitive impairment in CKD patients. About 10%-40% of CKD patients experience a decline in cognitive function. This study aims to determine the factors that influence the occurrence of cognitive impairment in hemodialysis patients. This study was conducted at Mohammad Hoesin Hospital Palembang in October-November 2022. Cognitive decline was detected by examination of the Montreal Cognitive Assessment-Indonesian version (MoCA-Ina) while other variables were obtained through interviews. The data were analyzed with Chi-square or Fisher exact tests. Age, education level, and age at hemodialysis initiation affect global cognitive function in CKD patients. In cognitive domain analysis, a significant relationship was found between age and duration of hemodialysis and attentional function, as well as the impact of age, sex, and age at hemodialysis initiation on executive/visuospatial function. Several demographic and hemodialysis characteristics are associated with cognitive decline in hemodialysis patients. Education and periodic cognitive screening are necessary to prevent and detect cognitive decline in these at-risk populations.
Discrepant Results of Flexible Endoscopic Evaluation of Swallowing (FEES) and Videofluoroscopy Swallowing Study (VFSS) in Myasthenia Gravis’ Patient Tamin, Susyana; Octavia, Devianty
Jurnal Profesi Medika : Jurnal Kedokteran dan Kesehatan Vol 18 No 1 (2024): Jurnal Profesi Medika : Jurnal Kedokteran dan Kesehatan
Publisher : Fakultas Kedokteran UPN Veteran Jakarta Kerja Sama KNPT

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33533/jpm.v18i1.7942

Abstract

Myasthenia gravis (MG) is an autoimmune neuromuscular disorder that causes weakness in skeletal muscles. Dysphagia is an early symptom that is often found in 6-15% of patients with myasthenia gravis. Flexible Endoscopic Evaluation of Swallowing (FEES) and Video Fluoroscopic Swallowing Study (VFSS) examinations are routinely used to diagnose dysphagia. This paper reports a case of Male, 51 years old diagnosed with neurogenic oropharyngeal dysphagia due to MG. Swallowing evaluation post-therapy and rehabilitation programs were carried out. Interestingly both FEES and VFSS had a significant discrepant result. In cases of dysphagia due to MG, when interpreting objective swallowing function examination, confounding factors such as fatigue, timing of examinations, and time of taking medication specifically anticholinesterase (Pyridostigmine), should be taken into consideration.

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