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Jurnal Profesi Medika: Jurnal Kedokteran dan Kesehatan
Published by Universitas Pembangunan Nasional Veteran Jakarta
ISSN : 02163438     EISSN : 26211122     DOI : -
Core Subject : Health,
Health Professions Medicine & Pharmacology
Arjuna Subject : -
Articles 244 Documents
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Knowledge Level and Beliefs of Mothers of Children Under 5 Years of Age About Childhood Vaccinations Turhan Aksoku, Berna; Aypak, Cenk; Güven, Deniz
Jurnal Profesi Medika : Jurnal Kedokteran dan Kesehatan Vol 18 No 1 (2024): Jurnal Profesi Medika : Jurnal Kedokteran dan Kesehatan
Publisher : Fakultas Kedokteran UPN Veteran Jakarta Kerja Sama KNPT

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33533/jpm.v18i1.7984

Abstract

Vaccination prevents infectious diseases and mother’s consent is key to increasing childhood vaccination rates. The aim of this study was to assess mothers' knowledge, and beliefs about childhood vaccinations, as well as the impact of these factors on their vaccination behaviors. A descriptive cross-sectional study of 320 mothers was conducted. The data were collected using a questionnaire form. Most of mothers (98.4%) have their children fully vaccinated through the Extended Immunization Program (EIP), 96.6% of cases support vaccines necessity. Vaccine hesitancy was 7.8%, vaccine refusal was 1.6%. The majority of mothers believe that the most common side effects of vaccines are fever (53.4%). Mothers were not adequately informed about EIP were 42.2%, and 57.5% of them had not received non-EIP vaccines, and 33.1% cited lack of knowledge as the reason. The majority of cases (73.7%) received information about EIP from a doctor. Parents' educational status, higher family income, and having more than three children significantly increased non-EIP vaccination rates but had no significant effect on EIP vaccination (p<0.05). Mothers still support EIP, but vaccine hesitancy is growing due to a lack of information. It is critical to assess mothers' knowledge and beliefs about vaccination, and social awareness is also required.
IgG AND CD4+ Responses Post Immunization With Cidr1α-Pfemp1 Recombinant Protein Istinaroh, Nurul; Sulistyaningsih, Erma; Dewanti, I Dewa Ayu Ratna
Jurnal Profesi Medika : Jurnal Kedokteran dan Kesehatan Vol 18 No 2 (2024): Jurnal Profesi Medika : Jurnal Kedokteran dan Kesehatan
Publisher : Fakultas Kedokteran UPN Veteran Jakarta Kerja Sama KNPT

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33533/jpm.v18i2.7658

Abstract

Malaria vaccine is urgently needed to eradicate malaria. The complexity of Plasmodium sp life cycle and host immunity to malaria have become the forces for developing peptide-based malaria vaccines using recombinant technology. The CIDR1α-PfEMP1 (cysteine-rich interdomain region 1α of Plasmodium falciparum erythrocyte membrane protein 1) is vital in malaria pathogenicity, making it a malaria vaccine candidate. This study investigated the IgG and CD4+ responses generated after the CIDR1α-PfEMP1 recombinant protein immunization in Wistar rats. The rats were divided into a control group, injected with 0.9% NaCl, and a treatment group, subcutaneously injected with 150 µg of purified CIDR1α-PfEMP1 recombinant protein. Injection was conducted thrice with a three-week interval. Blood samples were extracted every two weeks after immunization. IgG and CD4+ concentrations were measured using ELISA. Data were analyzed using the independent T-test and Mann-Whitney test based on the data distribution. IgG and CD4+ concentrations increased along with the injection frequency. Significant differences between the control and treatment groups were observed in IgG concentrations after all injections and CD4+ level only after secondary II immunization (p<0.05). In conclusion, the CIDR1α-PfEMP1 recombinant protein induces humoral and cellular immune responses through increased IgG and CD4+ concentrations, making it a potential malaria vaccine candidate.
Shallot Peel Infusion Prevents Bronchus Epithelium Thickening And Cilia Shortening In Cigarette Smoke-Induced Wistar Rats Bintang, Muhammad Farrel Ravidinata Masoga; Dewi, Rosita; Efendi, Erfan; Helianti, Dina; Rachmania, Sheilla
Jurnal Profesi Medika : Jurnal Kedokteran dan Kesehatan Vol 18 No 2 (2024): Jurnal Profesi Medika : Jurnal Kedokteran dan Kesehatan
Publisher : Fakultas Kedokteran UPN Veteran Jakarta Kerja Sama KNPT

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33533/jpm.v18i2.7804

Abstract

Cigarette smoke exposure is the major risk of chronic obstructive pulmonary disease, the third cause of death worldwide. Inhaled smoke triggers oxidative stress resulting in airway epithelium thickening and cilia shortening. Shallot (Allium cepa L.) peel contains flavonoid which can neutralize oxidative stress. This study aims to determine correlation between shallot peel infusion (SPI), bronchus epithelium thickness, and cilia length in cigarette smoke-induced rats; and establish maximum effective dose of SPI. Rats were divided into normal; cigarette; SPI 125, 250, 500, 1,000, 2,000 mg/kgBW groups. Two hours after administration, rats were exposed to cigarette smoke 2 cigarettes/day for 28 days. Hematoxylin-eosin-stained bronchus was observed and variable measurements were carried out. Comparation tests of epithelium thickness and cilia length between normal and cigarette group showed significant difference (p<0.05); Pearson coefficient between SPI dose and epithelium thickening was -0.614, Spearman coefficient between SPI dose and cilia length was 0.860; and maximum effective dose to prevent bronchus epithelium thickening and cilia shortening are 1,275.4 mg/kgBW and 1,325.8 mg/kgBW. In conclusion, the higher the SPI dose, the lower epithelium thickness, the higher cilia length. Maximum effective dose of SPI to prevent bronchus epithelium thickening and cilia shortening are 1,275.4 mg/kgBW and 1,325.8 mg/kgBW.
Analysis of Factors Affecting Fatigue Level in Online Motorcycle Taxi Drivers in Denpasar City Sahadewa, Anak Agung Gede Anandyaksa Waranggana; Apsari, Putu Indah Budi; Wijaya, Putu Austin Widyasari
Jurnal Profesi Medika : Jurnal Kedokteran dan Kesehatan Vol 18 No 2 (2024): Jurnal Profesi Medika : Jurnal Kedokteran dan Kesehatan
Publisher : Fakultas Kedokteran UPN Veteran Jakarta Kerja Sama KNPT

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33533/jpm.v18i2.8564

Abstract

Ojek online is an online-based transportation that is currently popular. Along with the rise of this drivers, it causes an increase in the number of accidents that occur. Factors that cause fatigue consist of age, gender, workload, length of service, and duration of work. Fatigue is the most workload experienced by online motorcycle taxi drivers in Denpasar. The purpose of this research is to determine the factors that affect job fatigue in online motorcycle taxi drivers, such as age, gender, smoking habits, length of work, duration of work, and body mass index. This study is an observational study with a cross sectional design and used the Industrial Fatigue Research Committee questionnaire. The subjects of this study were online motorcycle taxi drivers in Bali, especially in Denpasar City, totaling 106 people selected based on the inclusion and exclusion criteria using purposive sampling technique. The majority of this subjects are male (51,2%), duration of work of >8 hours (69,1%), work for >2 years (61,5%), aged 37 years (66,1%), and obese (100%) experiencing job fatigue. The results of the analysis obtained smoking factors, work duration, length of work, age, and body mass index affect work fatigue in online motorcycle taxi drivers.
Validation of Sistem Pelatihan Otak or SiPETA A Digital Cognitive Remediation Therapy for Children dewi, Suzy Yusna; Pasiak, Taufiq Fredrik; Theresa, Ria Maria; Harfiani, Erna
Jurnal Profesi Medika : Jurnal Kedokteran dan Kesehatan Vol 18 No 2 (2024): Jurnal Profesi Medika : Jurnal Kedokteran dan Kesehatan
Publisher : Fakultas Kedokteran UPN Veteran Jakarta Kerja Sama KNPT

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33533/jpm.v18i2.8909

Abstract

The development of cognitive abilities is closely related to children's academic achievement and behavioral issues. Children prefer media that use visual and auditory elements to optimize their attention. Therefore, media are needed to enhance attention and memory, thus improving their understanding of lessons and impacting academic performance. This study aims to validate SiPETA as a digital cognitive remediation therapy for children to enhance learning abilities. SiPETA was developed based on a prototype of learning methods focused on Attention, Memory, and Self-Regulation. The platform contains social intelligence stories based on Bloom's taxonomy, categorizing cognitive abilities into six levels. The research method includes three stages. In the first stage, face validity was tested by 13 experts in child development and special education who evaluated the platform's narratives using the Delphi method. In the second stage, content and construct validity of SiPETA were tested by experts using the Lawshe method. In the third stage, the usability of the SiPETA application was tested on 12 elementary school children using the Lawshe method. The results showed that SiPETA is valid, reliable, and ready for training. SiPETA can be a valuable tool for teachers and parents to help children develop cognitive skills and improve academic achievement.
Heightened Blood Pressure, but not Pulse Rate, Response to Orthostatic Challenge in Normotensive Subjects with Family History of Hypertension Awisarita , Wiwara; Jenie, Ikhlas Muhammad
Jurnal Profesi Medika : Jurnal Kedokteran dan Kesehatan Vol 18 No 2 (2024): Jurnal Profesi Medika : Jurnal Kedokteran dan Kesehatan
Publisher : Fakultas Kedokteran UPN Veteran Jakarta Kerja Sama KNPT

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33533/jpm.v18i2.9063

Abstract

Whether exaggerated cardiovascular response to postural changes among normotensive subjects with family history of hypertension does exist is not reported yet. Male and female normotensive subjects with (n=16) and without (n=14) hypertensive parents did postural changes from supine to standing. Systolic blood pressure, diastolic blood pressure and pulse rate were measured during supine and immediately after standing. The median value of the delta systolic blood pressure, diastolic blood pressure and pulse rate from all samples were used to classified exaggerated cardiovascular responses. The differences in the proportion of subjects with exaggerated cardiovascular responses were analysed with Chi square. P value <0.05 was considered significant. Proportion of normotensive subjects who had exaggerated systolic (≥3.5 mm Hg) or diastolic (≥2 mm Hg) blood pressure responses to postural changes were significantly higher in those with parental history of hypertension as compared to those without parental history of hypertension. Proportion of subjects who had exaggerated pulse rate (≥12 bpm) response to postural changes was not significantly different between the two groups. Normotensive young adults with family history of hypertension demonstrated heightened blood pressure, but not pulse rate, responses to orthostatic challenge from supine to standing.
Clinical Characteristics and Management of Pediatric Eye Trauma in National Tertiary Eye Hospital in Indonesia Axa, Alya Putri; Amiruddin, Primawita Oktarima; Caesarya, Sesy
Jurnal Profesi Medika : Jurnal Kedokteran dan Kesehatan Vol 18 No 2 (2024): Jurnal Profesi Medika : Jurnal Kedokteran dan Kesehatan
Publisher : Fakultas Kedokteran UPN Veteran Jakarta Kerja Sama KNPT

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33533/jpm.v18i2.9087

Abstract

Eye trauma is a major cause of vision problems in children, leading to visual impairment and blindness. This issue has significant global implications, affecting children psychologically and socially. According to the American Academy of Pediatrics, 66% of all eye traumas occur in individuals under 16, with the highest occurrence between ages 9 and 11. We conducted a retrospective descriptive study using medical records of pediatric patients aged 0 - 18 years who experienced eye trauma from January to December 2022 at the National Eye Center-Cicendo Eye Hospital. There were 190 patients included in this study. The majority of patients were male (69.47%) and the most common age group affected was 6 - 12 years (33.16%). Leading causes of eye trauma were blunt trauma (58.95%). The common management for eye trauma in this study is operative or medical procedures (67,37%) This study provides valuable information on the characteristics and management of eye trauma in children, which can contribute to the development of prevention strategies and appropriate interventions. Understanding the patterns of eye trauma and implementing comprehensive care can help prevent blindness and minimize visual impairment. Keywords: Eye Trauma; Children; Management
The Effect Honey Has on SOD and Caspase9 Levels with Exposure to Cigarette Smoke in Wistar Rats Fentri, Ela; Isradji, Israhnanto; Trisnadi, Setyo
Jurnal Profesi Medika : Jurnal Kedokteran dan Kesehatan Vol 18 No 2 (2024): Jurnal Profesi Medika : Jurnal Kedokteran dan Kesehatan
Publisher : Fakultas Kedokteran UPN Veteran Jakarta Kerja Sama KNPT

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33533/jpm.v18i2.9102

Abstract

Cigarettes are a source of exogenous free radicals which disrupt the balance between free radicals and antioxidants in the body, causing oxidative stress. The aim of this study was to determine the effect of giving honey (Mel depuratum) on SOD and caspase-9 levels in Wistar rats exposed to cigarette smoke. This research used a laboratory experimental approach with a post-test only control group design. 24 Wistar rats were divided randomly into 4 groups then analysis tests were carried out using the One-Way ANOVA test and followed by the Post-Hoc LSD test. The results showed that the mean SOD levels in groups K1, K2, K3, K4 were 73.51 ± 1.68, 21.72 ± 2.23, 52.08 ± 2.03, and 73.51 ± 1.68. The results of the One Way Anova test showed a significant difference in SOD levels with a value of p = 0.000. The results of the LSD Post-Hoc Test showed that SOD levels between groups had significant differences in all groups (p=0.000). The IHK staining results showed that samples K1 and K4 were negative, while K2 showed strong positive and K3 was moderately positive.
Prostate volume’s effect on IPSS in patients over 50 with LUTS at RSUD Arjawinangun Auliya Sabilla Rosyada; Yudi Amiarno; Ferdy Ardiansyah; Siti Maulidya Sari
Jurnal Profesi Medika : Jurnal Kedokteran dan Kesehatan Vol 18 No 2 (2024): Jurnal Profesi Medika : Jurnal Kedokteran dan Kesehatan
Publisher : Fakultas Kedokteran UPN Veteran Jakarta Kerja Sama KNPT

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

The prostate is a gland that is part of the male reproductive system, located just below the bladder and surrounding the urethra. The prostate plays a role in producing semen, which nourishes and transports sperm. The International Prostate Symptom Score (IPSS) is a self-administered questionnaire used to assess symptoms of Benign Prostatic Hyperplasia (BPH). This study evaluates the relationship between prostate volume measured through transabdominal ultrasound and the International Prostate Symptom Score (IPSS) in patients aged 50 and above with Lower Urinary Tract Symptoms (LUTS) at RSUD Arjawinangun. The method involves using primary data (questionnaires) and performing prostate volume measurements via transabdominal ultrasound on 20 patients. The data will then be analyzed using SPSS version 26 with Spearman's test. Univariate results show that 12 patients experienced severe IPSS scores. The characteristic of prostate volume measured by transabdominal ultrasound was most found to be normal, with 12 patients having this volume. There was no significant relationship between prostate volume and the International Prostate Symptom Score (IPSS) in patients aged 50 and above with Lower Urinary Tract Symptoms (LUTS) at RSUD Arjawinangun, with a p-value of 0.811.
Differences in Corpse Stiffness (Rigor Mortis) of Organophosphate-Induced and Ordinary (Decerebrated) Dead Wistar Rats : A Randomized Experimental Study Nugroho, Novianto Adi; Zahrawan, Arzaq Fikrian; Wujoso, Hari; Atmoko, Wahyu Dwi
Jurnal Profesi Medika : Jurnal Kedokteran dan Kesehatan Vol 18 No 2 (2024): Jurnal Profesi Medika : Jurnal Kedokteran dan Kesehatan
Publisher : Fakultas Kedokteran UPN Veteran Jakarta Kerja Sama KNPT

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33533/jpm.v18i2.9215

Abstract

Corpse Stiffness (rigor mortis) is a secondary sign of death that can be used to estimate the time and cause of death. Organophosphates are the most toxic pesticides and often cause poisoning until death in humans. This study aims to determine the differences in corpse stiffness (rigor mortis) due to organophosphate poisoning and ordinary death (decerebration) using Wistar rats. The parameters of corpse stiffness (rigor mortis) used include 4 aspects: Corpse Stiffness Appearance, Perfect Formation of Corpse Stiffness, Persistent Corpse Stiffness, and Relaxation of Corpse Stiffness. Data were processed with univariate analysis and then tested with the Independent Sample T-test. There was a significant difference (p<0.05) in the duration of the appearance, perfect formation, persistent and relaxation of corpse stiffness between the control group and the treatment group. Meanwhile, there was no significant difference (p>0.05) in persistent corpse stiffness duration between the control and treatment groups, although there was a slight difference in the mean. Between ordinary and died rats due to organophosphate induction, there was a significant difference in the duration of appearance, perfect formation, and relaxation of corpse stiffness. However, there was no significant difference in the duration of persistent stiffness. Keywords: Organophosphates; Poisoning; Corpse Stiffness; Rigor Mortis

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