cover
Article Per Year (5 Year)
All
Home Page
OAI Link
Editorial Team
Contact
Reviewer
Google Scholar
Contact Name
-
Contact Email
-
Phone
-
Journal Mail Official
-
Editorial Address
-
Location
Kota medan,
Sumatera utara
INDONESIA
Majalah Kedokteran Nusantara The Journal Of Medical School
Published by Universitas Sumatera Utara
ISSN : -     EISSN : -     DOI : -
Core Subject : Health,
Health Professions Medicine & Pharmacology
Arjuna Subject : -
Articles 181 Documents
 10   11   12   13   14 
Metabolisme Protein Pada Anak Sakit Kritis Syarif, Erlita Wienanda; Lubis, Munar; Yanni, Gema Nazri
Majalah Kedokteran Nusantara The Journal Of Medical School Vol 50, No 3 (2017): The Journal of Medical School
Publisher : Fakultas Kedokteran USU

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Hospital malnutrition is known as a risk factor for mortality and morbidity in children, adolescents, and adults. Critically ill child more prone to suffer from malnutrition during treatment. This is because protein metabolism in critically ill children in different to the healthy children. Protein metabolism in critically ill children influenced by catabolic hormones triggered by stressful state resulting in increased protein breakdown. Therefore the protein requirement for critically ill children is different from healthy children. There are several methods of evaluation that can be used to evaluate the protein metabolism status, among others anthropometry, nitrogen balance, and tracer isotope. The importance of maintaining the balance of formation and protein breakdown must be one of the targets of nutritional therapy in the pediatric intensive care unit, thus improving treatment outcomes.Keyword : critically ill, protein metabolism, children
Update Diagnosis dan Tatalaksana Meningitis Tuberkulosa Anak Elvina, Fadhilah; Dimyati, Yazid; Saing, Johanes H.; Amelia, Fereza
Majalah Kedokteran Nusantara The Journal Of Medical School Vol 50, No 3 (2017): The Journal of Medical School
Publisher : Fakultas Kedokteran USU

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Tuberculous meningitis is the most devastating manifestation of pediatric tuberculosis (TB). Nowadays with the increase resistancy of M. tuberculosis, delay of antituberculosis administration and increase of HIV patient, morbidity and mortality of patient with tuberculosis are also increased. Tuberculous meningitis is diagnosed by clinical or laboratory findings. Recently, WHO develop Xpert as diagnostic tools, IGRA, NAATs, PCR, and any other tools help to diagnosed TB. Management with antituberculous drugs, antiinflammation and management of complication such as hydrocephalus.Keyword : tuberculous meningitis, diagnosis, management
FUNGSI TIROID PADA ANAK OBESITAS Sitompul, Dame Lamtiur; dr, Hakimi
Majalah Kedokteran Nusantara The Journal Of Medical School Vol 50, No 3 (2017): The Journal of Medical School
Publisher : Fakultas Kedokteran USU

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Levels of Thyroid Stimulating Hormone (TSH) can have a positive correlation with Body Mass Index(BMI), which is found TSH levels increased slightly with increased leptin in obese children. Increasing ofTSH, Free Triiodotironine (FT3) and leptin levels in obese children and their weight loss causes adecrease in serum TSH, FT3, and leptin levels, supporting the hypothesis that alterations in thyroidfunction in obesity are reversible with weight loss.Keywords: thyroid function, obesity, children
Masalah Perilaku pada Anak Sindroma Nefrotik Barus, Ratna Sari; Ramayani, Oke Rina; Siregar,, Rosmayanti; Siregar, Beatrix
Majalah Kedokteran Nusantara The Journal Of Medical School Vol 50, No 3 (2017): The Journal of Medical School
Publisher : Fakultas Kedokteran USU

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Nephrotic syndrome (NS) is the most common chronic kidney disease in children.As one of chronic diseases having remission and relapse periods and requiring longterm corticosteroid theraphy, NS has impacts on children’s biologic, social, and behavior functions which will affect psychosocial developmen of the children and their families. Untill now there were difficulties in determining behavioural problem in children with NS and to determine whether it was caused by the disease itself or by chronic condition or by the side effect of steroid theraphy. High-dose steroid usage, mainly in the early treatment phase of NS is proven to correlate with internalization behavioural problem, manifesting with anxiety, depression, aggressiveness, and retraction from social life.It is suggested to pay more attention to psychosocial problems in children with NS especially in the early phase of steroid theraphy.Keywords : nephritic syndrome, children, behavioral problem, steroidTinjauan Pustaka
Perubahan Faal Paru pada Penderita Efusi Pleura setelah Tindakan Aspirasi Cairan Pleura Nasution, Morris Shofwan; Widirahardjo, Widirahardjo
Majalah Kedokteran Nusantara The Journal Of Medical School Vol 51, No 1 (2018): The Journal of Medical School
Publisher : Fakultas Kedokteran USU

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Introduction Pleural effusion is an excessive accumulation of fluid in the pleural space, related to the underlying diseases. Pleural effusion was associated with restrictive ventilatory impairment, and a frequent of symptom with dypsnea. Therapeutic thoracocentesis is aspiration of fluid from the pleural space, the volume removed may be associated with a decrease in the size of thoracic cavity. The aim of this study is to assess the pulmonary function with pleural effusion, performed before and after twenty four hours the therapeutic thoracocintesis Methods This is a propective study with data analysis with paired t-test performed on thirty patients. Subjects were all patients with pleural effusion who were documented clinically and fulfilling inclusion and exclusion criteria between January 2014 and August 2015. Subjects underwent chest x ray to therapeutic thoracocintesis. Spirometry were performed before and after twenty four hours thoracocentesis. Results The study population consisted of thirty patients, 18 male (60%) with a mean age of 49+14.85 years, average weight 52+11.27 kg, average height 159.23+8.52cm, and average of pleural fluid 707+279.25 cc. Pulmonary function before and after twenty four hours thoracocentesis (SVC: 195.31 ml, FVC:165.21 ml, FEV1: 115.40 ml). Statistically significant improvement pulmonary function following after therapeutic thoracocintesis (p<0,05). Conclusion Improvement pulmonary function was observed after therapeutic thoracocintesis in patient with pleural effusion.. Keywords : Pleural effusion, pulmonary function, therapeutic thoracocentesis
Kadar hs-CRP pada Pasien DM tipe-2 Dengan dan Tanpa Hipertensi Efi Ramadhan; Ozar Sanuddin; Dharma Lindarto
Majalah Kedokteran Nusantara The Journal Of Medical School Vol 49, No 2 (2016): The Journal of Medical School
Publisher : Fakultas Kedokteran USU

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Introduction : More than 50% of patients with type-2 diabetes have hypertension. Hypertension contributes the development of cardiovascular disease. hs-CRP is an inflammation marker which is associated with cardiovascular risk. The aim of this study is to measure hs-CRP in type-2 diabetes with and without hypertension and to assess hs-CRP levels based on cardiovascular risk group.Methods : This study is an analytical observational cross-sectional study. Performed at the Department of Clinical Pathology Adam Malik Hospital, the total of type-2 DM subjects with and without hypertension is 56, with 28 in each group. Laboratory tests: complete blood count, blood sugar levels, HbA1C, SGOT, SGPT, Lipid Profile, hs-CRP.Results : There was significant differences in the average levels of hs-CRP in type-2 diabetic patients with hypertension (4.03±2.49) and without hypertension (1.98 ± 1.93), p = 0.001. In this study seen an increase in the average levels of hs-CRP is based on group risk of cardiovascular disease in patients with type 2 diabetes with and without hypertension (p= 0,001 ). In the group of type-2 diabetes with hypertension, may not find a mild risk of cardio-vascular disease. It shows the type 2 DM patients with hypertension is more at risk of cardio-vascular disease than type 2 DM without hypertension.Discussion : hs-CRP levels were higher in type-2 diabetes with hypertension and associated with the risk of cardiovascular disease. Conclusion : There are significant differences between the levels of hs-CRP type-2 diabetes with and without hypertension.Keywords :  type-2 diabetes, hypertension, hs-CRP 
Hubungan antara Red Blood Cell Count (RBC) dan Retinopati Diabetik pada Pasien Diabetes Melitus tipe 2 Irmayani Irmayani; Santi Syafril; Dharma Lindarto
Majalah Kedokteran Nusantara The Journal Of Medical School Vol 49, No 2 (2016): The Journal of Medical School
Publisher : Fakultas Kedokteran USU

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Background : Diabetic retinopathy is main complications of diabetes. Some studies suggest a relation between red blood cell count (RBC) and diabetic retinopathy. Diabetic retinopathy is diagnosed with funduscopic examination, while red blood cell count can be seen from the peripheral blood examination, with the result is a relation of a decreased red blood cell count with diabetic retinopathy.Objective : To determine the relation between RBC count and diabetic retinopathy in diabetic type 2 patients. So that these parameters can be used as prospective and reliable indicators to detect complication of diabetes mellitus in the target organs, specially the eyes as early as possible.Methods: This cross sectional study with measurement data from March - June 2015, there were  49 patients with type 2 diabetic examined from the anamnesis, examination of vital signs, physical examination, and examination of routin peripheral blood, HbA1C ,fasting and 2 hours post prandial glucose count, lipid profile and funduscopy, subsequently the patients were classified in to two group, the diabetic retinopathy and without diabetic retinopathy respectively.Results : From 49 subjects were included and observed in this study, from statistical analysis data found that there are relation between age (p=0,001), smoking habbit (p=0,006), hemoglobin (Hb) (p=0.002), duration of diabetic (p=0,0001) and  the RBC count with diabetic retinopathy (p= 0,0001 ). From multivariate analysis we found that RBC range lower than 4,8 billion/mm3 are independent predictor for the incidence of diabetic retinopathy.Conclusion : This study found a significant relation between RBC count and diabetic retinopathy and RBC also can predict the incidence of diabetic retinopathy in patient with diabetes.Keywords : RBC, diabetic retinopathy, diabetes.
Hubungan Nilai Mean Platelet Volume (MPV) dengan Derajat Sepsis Andi Raga Ginting; Endang Sembiring; Armon Rahimi
Majalah Kedokteran Nusantara The Journal Of Medical School Vol 49, No 2 (2016): The Journal of Medical School
Publisher : Fakultas Kedokteran USU

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Background : Sepsis is a major disease that affects millions of people worldwide every year. Almost all organs and systems were affected by sepsis. Hemostatic system is also affected. Easily accessible, inexpensive, and widely used laboratory tests that shows sepsis and the severity are important.Purpose : To investigate the relationship of the MPV values with the degree of sepsis and correlation MPV with procalcitonin.Method :  A cross sectional study was conducted. The subject with infection was treated in ward or Intensive Care Unit (ICU) in Adam Malik General Hospital, after fulfilling the inclusion criteria, full blood examination including MPV, procalcitonin, blood cultures was taken. The MPV values was compared between sepsis and non-sepsis, also between sepsis and severe sepsis. Then MPV values was correlated with procalcitonin.Results : Of the 50 patients with sepsis and 50 non-sepsis, found a significant difference in MPV levels of sepsis patients 10.97 (0.63) compared to the non-sepsis 9.17 (± 0.75), (p < 0.001). From the 17 patients sepsis and 33 severe sepsis patients also found a significant difference in MPV levels of severe sepsis patients 11,19 (0.64) compared with groups of sepsis patients 10.52 (0.27), (p < 0.001). And there is a strong correlation between MPV with procalcitonin r=0,702.Conclusion : The value of MPV is higher in patients sepsis and non-sepsis, and there is also a difference value of MPV in patients sepsis and severe sepsis. And also found there is correlation between MPV and procalcitonin.Keywords : sepsis, severe sepsis, mean platelet volume.
Kader Pemulihan Faktor VIII pada Pembatan Kriopresipitat Evi Musafni Silitonga; Zulfikar Lubis; Herman Hariman
Majalah Kedokteran Nusantara The Journal Of Medical School Vol 49, No 2 (2016): The Journal of Medical School
Publisher : Fakultas Kedokteran USU

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Pendahuluan :Terapi dengan Kriopresipitat terhadap pasien Haemophilia A mempunyai beberapa keuntungan dibandingkan F VIII concentrate yang dijual komersil seperti kecilnya kemungkinan timbulnya allogeneic – antibody (inhibitor), selain itu harga (cost)  dari  kriopresipitat jauh lebih murah dari commercial concentrate,  hal ini mengakibatkan Kriopresipitat  sangat penting bagi pengobatan Haemophilia A  di negara-negara yang sedang berkembang seperti di Indonesia. Faktor-faktor yang mempengaruhi faktor VIII dalam Kriopresipitat telah dipelajari dalam konteks program pembuatan komponen darah. Pada proses pembuatan Kriopresipitat harus melalui prosedur pembekuan, dan pelarutan serta pemutaran/centrifugasi. Sehingga menurut teori prosedur ini dapat membuat hilangnya sebagian aktivitas faktor VIII. Penelitian ini bertujuan untuk mengetahui berapa kehilangan aktivitas F VIII dan melihat berapa Kadar pemulihan faktor VIII selama pembuatan Kriopresipitat. Metode : Metode penelitian obsevasi analitik secara potong lintang di RSUP H.Adam Malik Medan, selama Maret-Mei 2015. Subjek penelitian adalah pendonor yang  darahnya  diambil oleh petugas Unit Transfusi Darah RSUP H. Adam Malik Medan. Yang memenuhi kriteria inklusi dan ekslusi.Hasil : Selama penelitian ini diperoleh 28 pendonor yang memenuhi kriteria inklusi dalam penelitian ini, yang kemudian darahnya di ambil untuk dilakukan pemeriksaan Faktor VIII. Dijumpai penurunan yang tidak signifikan konsentrasi Faktor VIII pada plasma awal (156.19  ± 32.79) dibandingkan dengan konsentrasi Faktor VIII pada Kriopresipitat (150.70± 29.08), dengan nilai (p > 0.05). Dijumpai penurunan yang signifikan konsentrasi Faktor VIII absolut (G1 unit)pada plasma awal (24599 ± 5163.9) dibandingkan dengan konsentrasi Faktor VIII absolut (G 2 unit) pada Kriopresipitat (5397.07± 1344.65), dengan nilai (p < 0.001). Setelah dihitung dengan rumus absolut ternyata Kadar pemulihan faktor VIII hanya 21.95%. Sehingga dapat diperkirakan kehilangan dari  FVIII absolute pada Kriopresipitat sekitar 78.05%.Kesimpulan : Terjadi kehilangan aktivitas maupun jumlah F VIII yang cukup besar dalam pembuatan Kriopresipitat dengan teknik Refrigerator-Centrifugation.Kata kunci : Hemofilia, Kriopresipitat, faktor VIII
Deteksi Immunoglobulin M dengan antigen Outer Membrane Protein (OMP) 50K-DA salmonella typhi pada demam tifoid Herawina E; Zulfikar Lubis; Ricke Loesnihari
Majalah Kedokteran Nusantara The Journal Of Medical School Vol 49, No 2 (2016): The Journal of Medical School
Publisher : Fakultas Kedokteran USU

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Introduction : Typhoid fever is a systemic infectious disease caused by Salmonella typhi. That is still widely found in the world and many developing countries that are mainly located in the tropical and subtropical. Clinical diagnosis of typhoid fever is difficult because there is no typical clinical manifestation, therefore we need laboratory tests. Typhidot IgM  is one of serological examination is a rapid examination with  of detecting the presence of  antibodies IgM of Outer membrane protein (OMP) 50KDa antigen in Salmonella typhi.The aim of this study was to assess the sensitivity and specificity of the IgM antigen examination of  Outer membrane protein (OMP) 50KDa Salmonella typhi  with blood culture.Methods : The method that was used in this study was diagnostic testing to compare rapid examination Typhidot IgM with blood cultures in  adult patients ≥ 18 years old, with fever≥38º,  fever ≥3 days, who were diagnosed with suspected typhoid fever or typhoid fever based on Nelwan score in Haji Adam Malik Hospital.Results : The number of subjects are 29 people, with 25 positive Typhidot IgM (86%) and 11 positive blood cultures (38%). The examination results of Typhidot IgM towards blood culture showed 100% sensitivity, 22% specificity, 45%  positive predictive value and 100% negative predictive value.Conclusion : The results of rapid examination Typhidot IgM  showed a good sensitivity and a poor specificity, with a negative predictive value of 100% which indicates that  rapid examination Typhidot IgM can not be use a diagnostic examination but Typhidot IgM can be use as an initial screening examination this means that Typhidot IgM  able to get rid of a case that really is not typoid fever.Keyword : Typhoid fever, rapid test Typhidot , Blood Cultures.

Page 12 of 19 | Total Record : 181

 10   11   12   13   14 

Filter by Year

2012 2018


Reset
Filter By Issues
All Issue Vol 51, No 4 (2018): The Journal of Medical School Vol 51, No 3 (2018): The Journal of Medical School Vol 51, No 2 (2018): The Journal of Medical School Vol 51, No 1 (2018): The Journal of Medical School Vol 51, No 1 (2018): The Journal of Medical School Vol 50, No 4 (2017): The Journal of Medical School Vol 50, No 3 (2017): The Journal of Medical School Vol 50, No 2 (2017): The Journal of Medical School Vol 50, No 1 (2017): The Journal of Medical School Vol 49, No 2 (2016): The Journal of Medical School Vol 48, No 1 (2015): The Journal of Medical School Vol 47, No 3 (2014): The Journal of Medical School Vol 47, No 2 (2014): The Journal of Medical School Vol 47, No 1 (2014): The Journal of Medical School Vol 46, No 3 (2013): The Journal of Medical School Vol 46, No 2 (2013): The Journal of Medical School Vol 46, No 1 (2013): The Journal of Medical School Vol 45, No 3 (2012): The Journal of Medical School Vol 45, No 2 (2012): The Journal of Medical School More Issue