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Jurnal Penelitian Farmasi Indonesia

jpfi
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Published by Sekolah Tinggi Ilmu Farmasi Indonesia Riau

ISSN : 2302187X EISSN : 26563614 DOI : -

Core Subject : Health,

Medicine & Pharmacology

Jurnal Penelitian Farmasi Indonesia adalah publikasi ilmiah berkala yang terbit dua kali dalam satu tahun (September dan Maret) dan menggunakan sistem peer-riview dalam seleksi makalah. Jurnal Penelitian Farmasi Indonesia menerima naskah publikasi tentang hasil penelitian, survei dan telaah pustaka yang erat kaitanya dengan bidang kefarmasian dan kesehatan.

Arjuna Subject : -

Articles 111 Documents

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Analisis Faktor-Faktor Yang Mempengaruhi Pilihan Karir Mahasiswa Farmasi Di Sekolah Tinggi Ilmu Farmasi Riau Yulia Indri Yani
Jurnal Penelitian Farmasi Indonesia Vol. 8 No. 1 (2019)
Publisher : Lembaga Penelitian Sekolah Tinggi Ilmu Farmasi Jl. Kamboja Simpang Baru-Panam, Pekanbaru, Riau 28293 Telp. (0761) 588006, Fax. (0761) 588007 e-mail: editor-jpfi@stifar-riau.ac.id

Employment contract or prospects in the field of pharmacy are very variable, but the pharmacy staff are not evenly distributed. This is probably due to the factors that influence the career choice of a pharmacy worker. The aim of this study was to determine the main factor influencing the choice of career and student career choice direction and see the impact of demographic data on factors influencing students' career choices. This type of research is a descriptive analytical study conducted using a survey. The sampling technique used is a stratified random sample. The respondents in this study were 120 students, consisting of student class of 2014, 2015, 2016 and 2017 at the School of Pharmacy Riau. From the survey, the vast majority of pharmacy students opted for a career in hospital (RS) 34.2%, in one after another with 27.5% pharmaceutical industry, University / Research Institute 26.7%, pharmaceutical wholesalers (PBF) 5.8% and pharmacy 5.8%. Based on the results of univariate data analysis, there are three very important factors that influence the career choices of students salary / income, (the benefits) and work environment. From the results of the unpaired t-test between male students and female there are three factors that have a significant difference, is a factor of salary / income, working hours flexible and geography, while in beginning students with the final level there is no significant difference of each factor factors that influence the choices of the student career.

Uji efek analgetik infusa daun sukun (artocarpus altilis forst) terhadap mencit putih ( mus musculus l) jantan diinduksi asam asetata 1% nisa aulia; novia sinata
Jurnal Penelitian Farmasi Indonesia Vol. 8 No. 1 (2019)
Publisher : Lembaga Penelitian Sekolah Tinggi Ilmu Farmasi Jl. Kamboja Simpang Baru-Panam, Pekanbaru, Riau 28293 Telp. (0761) 588006, Fax. (0761) 588007 e-mail: editor-jpfi@stifar-riau.ac.id

ABSTRACTA study of the analgesic effect of breadfruit leaf infusion (ArtocarpusaltilisForst) on male white mice (Musmusculus L) was induced by 1% acetic acid. This study aims to look at the effect of the analgesic effect of breadfruit leaf infusion (ArtocarpusaltilisForst) on male white mice (Musmusculus L) by using the Writhing Test method. Experimental animals were divided into 5 groups. The negative control group was only given aquadest, the positive group was given acetylsalicylic acid at a dose of 1.3 mg / 20 gBB suspended with 1% Na CMC, the treatment group was given breadfruit leaf infusion preparation (ArtocarpusaltilisForst) with a concentration of 5%, 10% and 20 %. The experimental animals were given an oral preparation of 1% BB, 30 minutes after which each group was induced with 1% acetic acid as much as 0.1 ml. The data obtained is processed using two-way Analysis of Variance (ANOVA). The results showed that breadfruit leaf infusion (ArtocarpusaltilisForst) had an analgesic effect similar to acetylsalicylic acid (positive control) at 10% and 20% concentrations, significantly different from negative controland 5% infusion concentration (p <0.05).

Identifikasi dan Uji Resistensi Bakteri pada Pasien Ulkus Diabetikum di Bangsal Interne RSUP Dr. M. Djamil Padang Ringga Novelni
Jurnal Penelitian Farmasi Indonesia Vol. 8 No. 2 (2019)
Publisher : Lembaga Penelitian Sekolah Tinggi Ilmu Farmasi Jl. Kamboja Simpang Baru-Panam, Pekanbaru, Riau 28293 Telp. (0761) 588006, Fax. (0761) 588007 e-mail: editor-jpfi@stifar-riau.ac.id

Diabetic ulcers is one of diabetic mellitus’s chronic complication such as open wound on the skin and can be accompanied by necrotic tissues. High blood glucose levels become a strategic area to the development of bacteria. This study aims to determine the bacterial agent that cause of diabetic ulcer and its resistance to antibiotics. The design of this study was true experiment with diabetic ulcers patients as the subject in the ward interne at RSUP Dr. M. Djamil Padang on period February - April 2019. In this study 10 samples of diabetic ulcer patients were obtained, then bacterial identification and antibiotic resistance test was done against 5 types of antibiotics ciprofloxacin, cefotaxime, meropenem, gentamicin and vankomicin. Consecutively most of bacteria found were Klebsiella pneumonia (40%), Staphylococcus epidermidis (60%). Proteus vulgaris (10%), Proteus mirabilis (10%), Pseudomonas aeruginosa (10%) and Staphylococcus aureus (10%). Ciprofloxacin and Cefotaxime had the highest level of bacterial resistance (40%), while Vancomicin is effective to used in Staphylococcus aureus and Staphylococcus epidermidis.

Uji Aktivitas Antijamur Minyak Atsiri Bawang Bombay ( Allium cepa L.) terhadap Pseudomonas aeruginosa Miftahur Rahmi
Jurnal Penelitian Farmasi Indonesia Vol. 8 No. 1 (2019)
Publisher : Lembaga Penelitian Sekolah Tinggi Ilmu Farmasi Jl. Kamboja Simpang Baru-Panam, Pekanbaru, Riau 28293 Telp. (0761) 588006, Fax. (0761) 588007 e-mail: editor-jpfi@stifar-riau.ac.id

Onions (Allium cepa L) contain essential oils which contain sulfur in the form of isothiocyanates or thiosulfinates which are known as antibacterial and antifungal. The aims of this study was to determine the antibacterial activity and minimum inhibitory concentration (MIC)of essential oils from onions (Allium cepa L) against Pseudomonas aeruginosa. This research was an experimental study using the Kirby-bauer method using discs. The results were obtained by concentration of 20%(C1), 10%(C2), 5%(C3), 2,5%(C4), 1,25%(C5), 0,625%(C6), and 0,312%(C7) provide the inhibition with an average diameter are 14,94 mm, 14,17 mm, 13,62 mm, 12,97 mm, 11,97 mm, 9,11 mm and 0 mm. From this research it can be concluded that essential oils from onions (Allium cepa L) can inhibit the growth of Pseudomonas aeruginosaand the minimum inhibitory concentration (MIC) of essential oils from onions (Allium cepa L) against Pseudomonas aeruginosawas at a concentration of 0,612% (C6) with an average diameter of 9,11 mm.

Pengetahuan Masyarakat tentang Suplemen Minuman Berenergi terhadap Risiko Penyakit Ginjal Kronik di Kelurahan Simpang Baru Kecamatan Tampan Pekanbaru Yolanda Fandra; septi muharni; ratna sari dewi
Jurnal Penelitian Farmasi Indonesia Vol. 8 No. 2 (2019)
Publisher : Lembaga Penelitian Sekolah Tinggi Ilmu Farmasi Jl. Kamboja Simpang Baru-Panam, Pekanbaru, Riau 28293 Telp. (0761) 588006, Fax. (0761) 588007 e-mail: editor-jpfi@stifar-riau.ac.id

Energy drink supplement is a health product that contains one or more substances that are nutritional (vitamins, minerals and amino acids) or drugs. This study aims to look at public knowledge about the use of energy drink supplements for the risk of chronic kidney disease in Simpang Baru district, Tampan District, Pekanbaru city. This research is an observational / survey research which is descriptive in nature. Sampling was done by purposive sampling, samples obtained in this study were 100 respondents who used energy drink supplements at least once a week. The results showed that community knowledge in the Simpang Baru sub-district was included in the sufficient category (64.83%) with the division of categories of knowledge about the definition of a supplement with enough energy drinks (62%), the content of the supplement with enough energy drinks (65.66%), the purpose / reason consume adequate energy drink supplements (75%), effects / risks after taking adequate energy drink supplements (69.6%) and when consuming energy drink supplement people in the Simpang Baru sub-district community have less knowledge level (52.33%). From these results it can be concluded that public knowledge about the use of energy drink supplements in Simpang Baru village, Tampan sub-district, Pekanbaru city is included in the sufficient category (64.83%).

UJI SIFAT FISIK TABLET SALUT ENTERIK KALIUM DIKLOFENAK GENERIK DAN GENERIK BERMEREK YANG BEREDAR DI APOTEK KECAMATAN SIAK HULU Iga Susanti
Jurnal Penelitian Farmasi Indonesia Vol. 8 No. 1 (2019)
Publisher : Lembaga Penelitian Sekolah Tinggi Ilmu Farmasi Jl. Kamboja Simpang Baru-Panam, Pekanbaru, Riau 28293 Telp. (0761) 588006, Fax. (0761) 588007 e-mail: editor-jpfi@stifar-riau.ac.id

Diclofenac potassium is a non-steroidal anti-inflammatory drug that is widely used and available in the form of generic tablets and branded generics. This study aims to determine the physical properties between generic and generic branded diclofenac enteric coated tablets circulated at the pharmacy in Siak Hulu District. This type of research is experimental with random sample selection and purposive sampling. Tests were carried out on 2 samples of generic enteric diclofenac enteric coated tablets and 1 sample of generic enteric diclofenac enteric coated tablets. Physical quality tests are carried out such as uniformity of size, hardness, friability, endurance, uniformity of weights, and disintegration time. Based on the results of testing all generic and generic branded potassium enteric coated tablets meet the requirements according to Indonesian Pharmacopoeia and other literature.

Isolasi dan Uji Aktivitas Antioksidan Senyawa Metabolit Sekinder dari Fraksi n-Butanol Daun Tin (Ficus carica L.) Varietas Brown Turkey Haris Nanda Prayoga; noveri rahmawati
Jurnal Penelitian Farmasi Indonesia Vol. 8 No. 1 (2019)
Publisher : Lembaga Penelitian Sekolah Tinggi Ilmu Farmasi Jl. Kamboja Simpang Baru-Panam, Pekanbaru, Riau 28293 Telp. (0761) 588006, Fax. (0761) 588007 e-mail: editor-jpfi@stifar-riau.ac.id

Tin leaf (Ficus carica L.) is one of the traditional medicines that has potential as an antioxidant. The purpose of this study was to isolate secondary metabolites and to test the antioxidant activity of pure isolates from the n-butanol fraction of tin leaves. Extraction was carried out by the fractionation method using n-hexane, ethyl acetate and n-butanol. Then the n-butanol fraction was separated by column chromatography and antioxidant activity was tested using the DPPH method. Pure isolate compounds labeled HNF-3, in the form of crystals, white with a melting point 189-191 ° C. Based on phytochemical examination data analysis, UV spectroscopy, FT-IR and 1H-NMR it can be concluded that the HNF-3 compound is a flavonoid glycoside group and has a moderate category of antioxidant activity with an IC50 value of 160.613 µg / mL.

Gambaran Perencanaan dan Pengadaan Obat di Puskesmas Rawat Jalan Kabupaten Rokan Hulu Tahun 2018 septia roza; erniza pratiwi
Jurnal Penelitian Farmasi Indonesia Vol. 8 No. 2 (2019)
Publisher : Lembaga Penelitian Sekolah Tinggi Ilmu Farmasi Jl. Kamboja Simpang Baru-Panam, Pekanbaru, Riau 28293 Telp. (0761) 588006, Fax. (0761) 588007 e-mail: editor-jpfi@stifar-riau.ac.id

A study was conducted on the description of drug planning and procurement at outpatient health centers in Rokan Hulu Regency in 2018. The purpose of this study was to look at the description of drug planning and procurement at outpatient health centers in Rokan Hulu Regency in 2018 referring to Permenkes number 74 years 2016 and see the suitability of the implementation of planning and procurement in outpatient health centers in Rokan Hulu Regency. This type of research is quantitative descriptive observational with a retrospective data collection from January to December 2018. The sample used was 13 outpatient health centers and 80 drug samples in the LPLPO. The results of his research are based on the Permenkes assessment element number 74 of 2016, the overall outpatient puskesmas drug planning system meets the requirements with a percentage of 97.43% with a very good category and the drug procurement system has reached 100%. Based on the results of conformity assessment, the suitability of drug planning reaches a percentage of 90.3% and suitability of drug procurement reaches a percentage of 79.90%.

Kepuasan Pasien Penyakit Kronik terhadap Pelayanan Resep di Apotek Daerah Pesisir Surabaya Oki Nugraha Putra
Jurnal Penelitian Farmasi Indonesia Vol. 8 No. 1 (2019)
Publisher : Lembaga Penelitian Sekolah Tinggi Ilmu Farmasi Jl. Kamboja Simpang Baru-Panam, Pekanbaru, Riau 28293 Telp. (0761) 588006, Fax. (0761) 588007 e-mail: editor-jpfi@stifar-riau.ac.id

Apotek ialah tempat untuk melakukan pekerjaan kefarmasian dan penyaluran perbekalan farmasi kepada masyarakat. Pelayanan kefarmasian pada saat ini telah bergeser orientasinya yaitu dari drug oriented menjadi Pharmaceutical Care. Salah satu bentuk pelayanan kefarmasian di apotek ialah pelayanan resep. Penelitian ini bertujuan untuk mengevaluasi kepuasan pasien pasien penyakit kronik terhadap layanan resep di beberapa apotek daerah pesisir timur surabaya berdasarkan lima dimensi mutu pelayanan, yaitu kehandalan (reliability), ketanggapan (responsiveness), jaminan (assurance), empati (emphaty) dan keberwujudan (tangibles). Penelitian ini merupakan penelitian observasional dengan desain cross sectional menggunakan kuesioner dengan skala likert. Sampel penelitian yakni pasien dengan penyakit kronik yang memenuhi kriteria inklusi. Pasien dengan penyakit kronik dipilih secara non random dengan metode consecutive sampling. Pengambilan data dilakukan pada bulan Agustus - November 2018. Data dari kelima dimensi mutu pelayanan dianalisis dengan metode SERVQUAL. Didapatkan 100 pasien dengan penyakit kronik yang memenuhi kriteria inklusi. Hasil menunjukkan bahwa nilai rata-rata gap antara harapan dan kinerja ialah -0,41 dengan nilai gap terbesar ditunjukan pada dimensi reliability yaitu -0,49. Pada tingkat kepuasaan secara keseluruhan didapatkan hasil sebesar 89,8%. Kesimpulannya ialah tingkat harapan pasien dengan penyakit kronik lebih tinggi daripada tingkat kinerja layanan resep yang diberikan oleh pihak apotek dengan tingkat kepuasaan pasien terhadap layanan resep yang tergolong baik. Kata Kunci : Apotek , Mutu Pelayanan, Pasien penyakit kronik, SERVQUAL

Farmakokinetika dan Bioavailability Senyawa Golongan Santon Revew Komprehensif Meri Susanti
Jurnal Penelitian Farmasi Indonesia Vol. 8 No. 2 (2019)
Publisher : Lembaga Penelitian Sekolah Tinggi Ilmu Farmasi Jl. Kamboja Simpang Baru-Panam, Pekanbaru, Riau 28293 Telp. (0761) 588006, Fax. (0761) 588007 e-mail: editor-jpfi@stifar-riau.ac.id

The use of herbs for treating various ailment dates back several centuries. Evidence-based verification of the efficacy of Herbal medicines is still frequently lacking. Of particular interest is the question of bioavailability to assess to what degree and how fast compounds are absorbed after administration of herbal. Of further interest is the elucidation of metabolic pathways, and the assessment of elimination routes and their kinetics. These data become an important issue to link data from pharmacological assays and clinical effects. A better understanding of the pharmacokinetics and bioavailability of phytopharmaceuticals can also help in designing rational dosage regimens. To provide provide a detailed picture on ADME parameters (absorption, distribution, metabolism, and excretion) of some xanthone active compound, this article reviews the pharmacokinetic profile of 7 xanthones bioactive compound from the year 2009 onward.

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