cover
Article Per Year (5 Year)
All
Home Page
OAI Link
Editorial Team
Contact
Reviewer
Google Scholar
Contact Name
Ajuk Sapar
Contact Email
ajuk.sapar@chemistry.untan.ac.id
Phone
+6281282990575
Journal Mail Official
anthoni.b.aritonang@chemistry.untan.ac.id
Editorial Address
Department of Chemistry, Faculty of Mathematics and Natural Sciences, Tanjungpura University Jl. Prof. Dr. Hadari Nawawi, Pontianak, Kalimantan Barat, Indonesia
Location
Kota pontianak,
Kalimantan barat
INDONESIA
Indonesian Journal of Pure and Applied Chemistry
Published by Universitas Tanjungpura
ISSN : 26208571     EISSN : 2620858X     DOI : -
Core Subject : Science,
Biochemistry, Genetics & Molecular Biology Chemistry
Indonesian Journal of Pure and Applied Chemistry (IJoPAC) was first established in 2018 as a scientific journal that accommodates researchers and education practitioners to publish scientific work and research results which are the results of experiments or literature studies in the field of chemistry. Publications are carried out periodically with three issues (January-April, May-August, September-December) in one volume per year. Published scientific work can be in the form of original articles, short communications and review results covering the fields of Physical chemistry, Organic chemistry, Analytical chemistry, Inorganic chemistry, Biochemistry / Biological Chemistry, Applied Chemistry. Focus and Scope of Indonesian Journal of Pure and Applied Chemistry covering the fields : Physical chemistry Organic chemistry Analytical chemistry Inorganic chemistry Biochemistry/Biological Chemistry Applied Chemistry
Arjuna Subject : Kimia(semua kategori) - Kimia (Lain-Lain)
Articles 5 Documents
 1 
Search results for , issue "Vol 8, No 1 (2025)" : 5 Documents clear
COMPARATIVE OF INHIBITORY EFFICIENCY OF LIGNIN EXTRACT OF NIPAH (Nypa fruticans Wurmb) PEEL AND FROND ON MILD STEEL IN HCl MEDIUM Emriadi, Emriadi; Sartika, Hilda; Pradiwi, Nailatul Zahrah; Stiadi, Yeni
Indonesian Journal of Pure and Applied Chemistry Vol 8, No 1 (2025)
Publisher : Tanjungpura University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26418/indonesian.v8i1.83186

Abstract

Lignin extract from nipah fruit skin and nipah frond (Nypa fruticans Wurmb) was effectively extracted and used as a corrosion inhibitor on mild steel samples. The corrosion inhibition efficiency of lignin extract in 1 N HCl solution was determined by the weight loss method and surface morphology analysis using an optical microscope. The measurement results showed that the highest efficiency was obtained at the concentration of lignin extract from fruit skin (ELBN) and nipah frond (ELPN) of 82.16 and 78.36%. The adsorption of lignin extract on the surface of mild steel follows the Langmuir isotherm adsorption and includes mixed adsorption leading to chemical adsorption.
KONVERSI KITIN MENJADI GLUKOSAMIN PADA PREPUPA MAGGOT (Hermetia illucens) SEBAGAI ALTERNATIF TERAPI SINDROM METABOLIK: NARRATIVE REVIEW Pamungkas, Pandu; Mubinan, Muhammad Fathan; Cahyadi, Achmad; Husnawati, Husnawati
Indonesian Journal of Pure and Applied Chemistry Vol 8, No 1 (2025)
Publisher : Tanjungpura University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26418/indonesian.v8i1.90282

Abstract

Maggots or larvae of the Black Soldier Fly (BSF) are decomposer insects widely cultivated in Indonesia due to their efficient and environmentally friendly ability to degrade organic waste. One of the key components in BSF is chitin, which accounts for approximately 17.93% (w/w) of its total body weight. Chitin can be converted into chitosan through deacetylation and hydrolyzed into glucosamine. Glucosamine has been shown to possess potential in the prevention and management of metabolic syndrome-related diseases such as hypercholesterolemia, diabetes, and obesity. This study explores the potential of glucosamine derived from BSF chitin in reducing the risk of metabolic syndrome. The method used is a literature review of various scientific articles. The findings indicate that glucosamine can activate the AMP-activated protein kinase (AMPK) pathway, which regulates glucose and lipid metabolism. AMPK activation inhibits adipogenesis, fatty acid synthesis, cholesterol production, and adipose tissue formation, positively affecting metabolic syndrome management. Therefore, glucosamine derived from BSF chitin has the potential to serve as a natural bioactive agent for the prevention of metabolic syndrome through AMPK pathway regulation.
MOLECULAR DOCKING AND ADME STUDIES OF STIGMASTEROL COMPOUNDS AS ANTI-BREAST CANCER Amir, Nur Insani; Nurfadillah, Arafah; Miladiarsi, Miladiarsi; Irma, Ade; Wahdaniar, Wahdaniar
Indonesian Journal of Pure and Applied Chemistry Vol 8, No 1 (2025)
Publisher : Tanjungpura University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26418/indonesian.v8i1.83224

Abstract

Molecular docking studies of stigmasterol (test ligand) and estradiol (control ligand) against the ER-α receptor were performed using PyRx software. This study aims to determine the interaction between stigmasterol ligands and ER-α receptors by the molecular docking method using PyRx. The study results show that stigmasterol and estradiol have the same binding energy value of -7.3 kcal/mol. The stigmasterol compound could therefore be used as a candidate for breast cancer drugs.
ISOLASI DAN KARAKTERISASI SENYAWA STEROID FRAKSI n-HEKSANA TERIPANG HITAM (Holothuria atra) ASAL PERAIRAN LEMUKUTAN KALIMANTAN BARAT Abrori, Sayyidus Dzaki; Sapar, Ajuk; Gusrizal, Gusrizal; Harlia, Harlia; Prayitno, Dwi Imam
Indonesian Journal of Pure and Applied Chemistry Vol 8, No 1 (2025)
Publisher : Tanjungpura University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26418/indonesian.v8i1.88526

Abstract

Black sea cucumber Holothuria atra is a marine organism from the family Holothuriidae, a source for developing raw pharmaceutical materials, and is abundant in the waters of Lemukutan Island. This study aims to identify steroid compounds from the n-hexane fraction of the black sea cucumber (H. atra) from Lemukutan waters using FTIR and ¹H-NMR instruments. The steps involved in this study include extraction (maceration and partition), phytochemical tests, fractionation (column chromatography), purification, and molecular structure identification. Phytochemical analysis of the n-hexane fraction of H. atra sea cucumber revealed the presence of secondary metabolites belonging to the groups of steroids, alkaloids, phenolics, terpenoids, and saponins. The result of the isolation was a relatively pure isolate with a weight of 0.0303 grams, yellowish white in color, and suspected to be a steroid compound. The results of the n-hexane fraction identification using FTIR showed the presence of several functional groups found in steroid compounds, such as aliphatic C-H bonds, olefinic =C-H bonds, C-O group, C=O group, C=C bond, and OH (hydroxyl) group. The results of the isolate identification using the ¹H-NMR instrument (500 MHz, CDCl₃) showed chemical shift similarities to the β-sitosterol compound from two different references.
TOTAL ALKALOID CONTENT , CYTOTOXICITY, AND SELECTIVITY OF ETANOL EXTRACT OF Litsea firma (Blume) Hook. F Hidayati, Putri Risti; Muharini, Rini; Erlina, Erlina
Indonesian Journal of Pure and Applied Chemistry Vol 8, No 1 (2025)
Publisher : Tanjungpura University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26418/indonesian.v8i1.95469

Abstract

Litsea firma (Blume) Hook. f., known locally as Medang Piawas, is a Lauraceae plant found in West Kalimantan, which was traditionally used as medicine and reported to contain alkaloids. This study determined the total alkaloid content in ethanol extracts of the roots, stems, and leaves. Phytochemical tests with Dragendorff, Mayer, and Wagner reagents confirmed alkaloid presence, with the highest intensity in stems, followed by leaves and roots. Quantitative analysis by UV-Vis spectrophotometry using caffeine and quinine standards showed the stem extract contained the highest alkaloid levels (18.289 mg CE/g and 2.299 mg QE/g). Cytotoxic activity was evaluated against cancer cell lines (4T1, MCF-7, T47D, WiDr, HeLa, Hep G2) and normal Vero cells using the MTT assay. The root extract exhibited weak cytotoxicity against WiDr cells (IC50 201"“500 µg/mL) but was inactive against other cancer and normal cells. Stem and leaf extracts showed no cytotoxic effects (IC50 >500 µg/mL). These findings indicate that L. firma contains notable alkaloids, predominantly in stems, although its ethanol extracts demonstrate limited cytotoxic activity.

Page 1 of 1 | Total Record : 5

 1 

Filter by Year

2025 2025


Reset
Filter By Issues
All Issue Vol 8, No 3 (2025) Vol 8, No 2 (2025) Vol 8, No 1 (2025) Vol 7, No 3 (2024) Vol 7, No 2 (2024) Vol 7, No 1 (2024) Vol 6, No 3 (2023) Vol 6, No 2 (2023) Vol 6, No 1 (2023) Vol 5, No 3 (2022) Vol 5, No 2 (2022) Vol 5, No 1 (2022) Vol 4, No 3 (2021) Vol 4, No 2 (2021) Vol 4, No 1 (2021) Vol 3, No 3 (2020) Vol 3, No 2 (2020) Vol 3, No 1 (2020) Vol 2, No 3 (2019) Vol 2, No 2 (2019) Vol 2, No 1 (2019) Vol 1, No 3 (2018) Vol 1, No 2 (2018) Vol 1, No 1 (2018) More Issue