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Jurnal Anestesiologi Indonesia
Published by Universitas Diponegoro
ISSN : 23375124     EISSN : 2089970X     DOI : -
Core Subject : Health,
Health Professions Medicine & Pharmacology Public Health
Jurnal Anestesiologi Indonesia (JAI) diterbitkan oleh Perhimpunan Dokter Spesialis Anestesiologi dan Terapi Intensif (PERDATIN) dan dikelola oleh Program Studi Anestesiologi dan Terapi Intensif Fakultas Kedokteran Universitas Diponegoro (UNDIP) bekerjasama dengan Perhimpunan Dokter Spesialis Anestesiologi dan Terapi Intensif (PERDATIN) cabang Jawa Tengah.
Arjuna Subject : -
Articles 17 Documents
 1   2 
Search results for , issue "Publication In-Press" : 17 Documents clear
ANALYSIS OF THE RELATIONSHIP BETWEEN INTENSIVE CARE UNIT PATIENT CHARACTERISTICS AND PATIENT MORTALITY AT ADAM MALIK HOSPITAL, MEDAN Putera, Rahadhi
JAI (Jurnal Anestesiologi Indonesia) Publication In-Press
Publisher : Perhimpunan Dokter Spesialis Anestesiologi dan Terapi Intensif

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14710/jai.v0i0.78266

Abstract

Background: Intensive Care Unit (ICU) is a vital unit in hospitals that treats critical patients with physiological instability or organ failure.Objective The general objective of this study is to determine the analysis of the relationship between patient characteristics and ICU mortality, , with the specific objective of analyzing the number of patients who died, characteristics (gender, age, type of disease, type of germ, route of entry, antibiotic use, tracheostomy time, and SOFA score), Methods: This study used a cross-sectional descriptive analytical design, Inclusion criteria were medical records of patients aged >18 years in the ICU ward, Result: Patient characteristics showed that most patients were admitted to the ICU via referral from other hospitals (132 patients). Fluoroquinolone antibiotics were the most frequently used (118 patients, 10.83%). 140 deceased patients had a SOFA score range of 10-11, with no significant difference (P 0.35). The highest mortality was observed in patients >65 years old (31.43%) and males (57.14%), often associated with respiratory diseases. Most deceased patients had a length of stay of 1-3 days (68.57%) and did not use ventilators (97.14%). Non-surgical patients had the highest mortality, with septic shock, acute myocardial infarct, and chronic heart failure as the primary diagnoses, Conclusion Mortality Cause of ICU patient is a multifactorial cause.
Correlation Between ScVO2, PCO2 Gap (Artery-Vein PCO2 Gradient) And Respiratory Quotient With Cardiac Output In Septic Shock Patients Anindita, Eliezer Iswara; Rakhmatjati, Pradana Bayu; Paramita, Dina; Pramadika, Taufan
JAI (Jurnal Anestesiologi Indonesia) Publication In-Press
Publisher : Perhimpunan Dokter Spesialis Anestesiologi dan Terapi Intensif

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14710/jai.v0i0.68347

Abstract

ABSTRACT Background: Septic shock is a life-threatening condition characterized by cardiovascular dysfunction, which can cause multi-organ failure and high mortality rates. Central venous oxygen saturation (SCVO2), PCO2 Gap, and Respiratory Quotient are potential markers of tissue perfusion and oxygenation, while cardiac output is an important indicator of cardiovascular function. So it is hoped that the results of this research can be a guide in the management and prediction of the prognosis of septic shock patients.Objective: To determine the correlation between central venous saturation (ScVO2), PCO2 Gap (Arterial-venous PCO2 Gradient) and Respiratory Quotient on Cardiac Output in septic shock patients.Methods: This observational study was conducted on 30 septic shock patients treated in the intensive care unit. The patient's blood sample is taken via a central venous catheter and arterial line to check central venous saturation (2ScVO2), PCO2 gap and calculate the respiratory quotient. Then cardiac output (Cardiac Output) is measured using Echohemodynamics.Results: Based on analysis using the Spearman Rho test, the results show that the correlation between ScVO2 and Cardiac Output has a correlation value of -0.367 (p = 0.046). The correlation between PCO2 Gap and Cardiac output has a correlation value of -0.520 (p=0.003). The correlation between respiratory quotient and cardiac output in this study had a correlation value of -0.833 (p < 0.001).Conclusion: There is a correlation between ScVO2, PCO2 Gap (Arterial-venous PCO2 Gradient) and Respiratory Quotient on Cardiac Output in septic shock patients. Keywords: Septic shock, ScVO2, PCO2 Gap, Respiratory Quotient, Cardiac output 
Base Deficit and Increased Lactate Level as Predictors of Blood Transfusion in Trauma Patients With Acute Bleeding at the Emergency Department RSUP Prof. dr. I.G.N.G. Ngoerah Nenoharan, Esther Gisela; Widnyana, I Made Gede; Hartawan, IGAG Utara; Wiryana, Made; Senapathi, Tjokorda Gde Agung; Sucandra, I Made Agus Kresna; Dewi, Dewa Ayu Mas Shintya; Pradana, FX Adinda Putra; Wigundwipayana, Kadek Anggie
JAI (Jurnal Anestesiologi Indonesia) Publication In-Press
Publisher : Perhimpunan Dokter Spesialis Anestesiologi dan Terapi Intensif

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14710/jai.v0i0.80615

Abstract

Background: Bleeding caused by trauma is still a prominent factor in death and organ system complications. Base deficit (BD) and lactate levels are experiencing disturbances which result in hypoxic acidosis conditions at the tissue and cellular levels.Objective: This study aims to determine the relationship between low base deficit levels, high lactate values, related to the need for blood transfusions in trauma patients with acute blood loss.Method: This research is an observational analytic study with a prospective cohort study design. The target population of this study were all trauma patients with acute bleeding admitted to the emergency room Prof Dr. dr. IGNG Ngoerah.Result: Age results showed a mean ± SD of 25.08 ± 6.38 years, the most gender was male, there were 36 subjects (72%), Hb levels had an average of ± 10.47 ± 2.85 g/dL, BMI results had mean ± SD 23.47 ± 3.54 kg/m2, the most common type of trauma was multiple trauma, the ISS score was found to have a mean ± SD 23.38 ± 9.09. The results for the value of the base level obtained a mean ± SD of 4.08 ± 5.08 mmol/L, with the transfusion group with an average of -6.41 ± 4.65 mmol/L. Low base level <-3 mmol/L had RR 3.69 (95% CI 1.83-7.45; P<0.001) and Adj RR 18.56 (95% CI 14.00-24.75; p=0.002 ). The average lactate result was found to have a mean ± SD 3.77 ± 2.29 and in the transfusion group 4.78 ± 2.38 mmol/L with high lactate levels (> 4 mmol/L) RR 5.53 (CI 95% 2, 25-13.64; P<0.001) and Adj RR 41.21 (95% CI 35.05-57.74; p<0.001).Conclusion: Low base deficit and high lactate levels are associated with the need for blood transfusions in patients with acute bleeding. 
Cytokine-Mediated Systemic Inflammation in Patient with Sepsis in ICU: A Systematic Literature Review and Meta- Analysis of Interleukin-6 and Tumor Necrosis - Yusuprihastuti, Maulitia Neny; Juniarti, Juniarti; Weni, Linda; Mukhtar, Diniwati; Satoto, Hari Hendriarto
JAI (Jurnal Anestesiologi Indonesia) Publication In-Press
Publisher : Perhimpunan Dokter Spesialis Anestesiologi dan Terapi Intensif

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14710/jai.v0i0.82097

Abstract

ABSTRACTObjectives: To systematically evaluate and quantify the prognostic value of circulating interleukin-6 (IL-6) and tumor necrosis factor-α (TNF-α) levels for mortality and disease severity in adult intensive care unit (ICU) patients with sepsis.Study design: This study was conducted as a systematic review and meta-analysis of observational studies and randomized controlled trials. Evidence quality was assessed using the Newcastle–Ottawa Scale for observational studies. Quantitative synthesis was performed using meta-analytic techniques.Data sources: A comprehensive literature search was performed in PubMed, Scopus, Web of Science, and Embase from database inception to the most recent available date. Reference lists of relevant articles were also manually screened to identify additional eligible studies.Data synthesis: Two studies evaluating IL-6 (196 ICU sepsis patients) demonstrated significantly higher IL-6 levels in non-survivors compared with survivors, with a large and consistent pooled effect size (SMD −1.92; 95% CI −2.27 to −1.57) and no interstudy heterogeneity, supporting IL-6 as a robust prognostic biomarker. TNF-α data from two studies (270 patients) also showed significantly elevated levels in non-survivors (SMD −2.70; 95% CI −3.05 to −2.35); however, substantial heterogeneity and slight funnel plot asymmetry reduced the certainty and generalizability of its prognostic value.Conclusions: Elevated IL-6 and TNF-α levels are associated with increased mortality in ICU patients with sepsis. IL-6 demonstrates more consistent and reliable prognostic performance, supporting its use for early risk stratification in critical care, whereas TNF-α may serve as a complementary biomarker.Registration: This systematic review and meta-analysis was conducted in accordance with PRISMA guidelines. Prospective registration in the PROSPERO database.Keywords:interleukin-6; intensive care unit; mortality; sepsis; tumor necrosis factor-α
Safe and Effective Perioperative Management in Patients with Atrial Septal Defect and Pulmonary Contusion: A Case Study with Supraclavicular Block RTH Supraptomo, RTH Supraptomo; Nugroho, Andy; Baihaqi Siddik, Muhammad
JAI (Jurnal Anestesiologi Indonesia) Publication In-Press
Publisher : Perhimpunan Dokter Spesialis Anestesiologi dan Terapi Intensif

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14710/jai.v0i0.78083

Abstract

Introduction: Peripheral nerve blocks are a safe and effective anesthetic option for patients with congenital heart disease, offering significant advantages over general anesthesia by minimizing cardiovascular and pulmonary risks. The supraclavicular brachial plexus block, in particular, provides excellent anesthesia for upper limb surgery with fewer intraoperative and postoperative complications, faster recovery, and improved pain control 2.Case : A 67-year-old woman with a large secundum ASD, severe pulmonary hypertension, right ventricular dysfunction, and bilateral lung contusions on the 10th day is scheduled for ORIF of a distal radius fracture. Given her high cardiopulmonary risk, regional anesthesia via ultrasound and Nerve Stimulator supraclavicular block using Levobupivacaine 0.375 % 20 ml was chosen to minimize hemodynamic instability and avoid complications from general anesthesia. The procedure is supported by intensive monitoring in the High Care Unit after the operation is complete, reflecting a careful, individualized approach for this high-risk geriatric patient.Discussion : Anesthetic management in patients with left-to-right shunt congenital heart disease requires preservation of hemodynamic stability and careful control of pulmonary and systemic vascular resistance. General anesthesia and mechanical ventilation may disturb the Qp:Qs balance and increase cardiopulmonary risk, particularly in the presence of pulmonary contusion, which predisposes to ventilator-induced lung injury and hypoxemia. In this case, ultrasound-guided supraclavicular brachial plexus block was selected to preserve spontaneous ventilation, maintain stable hemodynamics, and minimize pulmonary stress while providing effective surgical anesthesia.Conclusion Supraclavicular brachial plexus block may be a method to consider in patients with congenital heart disease and pulmonary contusion in patients with surgery below the shoulder.Keywords: Adult Congenital Heart Disease, Pulmonary Contusion, Radius fracture, Supraclavicular block 
CASE REPORT The role of CRRT in optimizing management of septic shock in patient with miastenia gravis improve outcome amin, robby al; irawany, vera
JAI (Jurnal Anestesiologi Indonesia) Publication In-Press
Publisher : Perhimpunan Dokter Spesialis Anestesiologi dan Terapi Intensif

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14710/jai.v0i0.83434

Abstract

Septic shock is a medical emergency characterized by organ dysfunction due to the body's uncontrolled response to infection, with a high mortality rate. The combination of Myasthenia Gravis (MG), pneumonia, and septic shock requires prompt and appropriate management to prevent further complications and improve patient prognosis. In this case, a 47-year-old female patient with Myasthenia Gravis developed septic shock due to pneumonia and showed significant clinical improvement after hemodynamic stabilization, appropriate antibiotic therapy, and the use of Continuous Renal Replacement Therapy (CRRT) to regulate electrolyte balance and eliminate inflammatory mediators. Despite the absence of plasmapheresis, comprehensive management of sepsis and organ dysfunction successfully improved the patient's prognosis. Optimal sepsis therapy and the use of CRRT without plasmapheresis may serve as an alternative approach in managing MG patients with septic shock due to pneumonia. Stabilizing the patient's condition through infection control, organ support, and comprehensive MG therapy plays a crucial role in successful treatment. Further research is needed to evaluate teh effectiveness of this approach in a broader patient population  
Risk Factors and Impact of Surgery Type on Prolonged PACU Stay: A Modified Data Analysis Noprianty, Richa
JAI (Jurnal Anestesiologi Indonesia) Publication In-Press
Publisher : Perhimpunan Dokter Spesialis Anestesiologi dan Terapi Intensif

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14710/jai.v0i0.76066

Abstract

Background: Prolonged Post-Anesthesia Care Unit (PACU) stay represents a critical indicator of postoperative care efficiency and resource utilization. Extended PACU duration can lead to patient accumulation, increased complication risks, and healthcare system strain.Objective: To identify and analyze risk factors associated with prolonged PACU stay following general anesthesia, with particular emphasis on surgery type as a dominant predictor.Methods: A cross-sectional observational study was conducted using modified data from 96 patients undergoing general anesthesia. Data collection included patient demographics, ASA physical status, pain scores, surgical duration, comorbidities, surgery type, anesthesia technique, and patient transfer timing. Statistical analysis employed chi-square tests and logistic regression to identify significant predictors of prolonged PACU stay (≥30 minutes).Result: Among 96 patients, 37.5% experienced prolonged PACU stay (≥30 minutes). Significant predictors included age (p=0.011), ASA physical status (p=0.012), anesthesia technique (p=0.035), and surgery type (p=0.001). Multivariate logistic regression identified surgery type as the dominant factor (p=0.004, OR=2.524, 95% CI: 1.355-4.700). Major surgeries demonstrated 60% prolonged stay rates compared to 21.8% for minor procedures. Pain intensity, surgical duration, comorbidities, and patient pickup time showed no significant association.Conclusion: Surgery type emerges as the primary determinant of prolonged PACU stay, with major surgical procedures significantly increasing recovery duration. These findings provide evidence-based guidance for perioperative planning, resource allocation, and quality improvement initiatives in postoperative care.

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