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INDONESIA
Indonesian Journal of Obstetrics and Gynecology (Majalah Obstetri dan Ginekologi Indonesia)
ISSN : 23386401     EISSN : 23387335     DOI : -
Core Subject : Health,
The Indonesian Journal of Obstetrics and Gynecology is an official publication of the Indonesian Society of Obstetrics and Gynekology. INAJOG is published quarterly.
Arjuna Subject : -
Articles 1,760 Documents
Tenascin-C is Strongly Expressed in the Anterior Vaginal Walls of Women with Pelvic Organ Prolapse Sulham, Risma N.
Indonesian Journal of Obstetrics and Gynecology Volume. 1, No. 4, October 2013
Publisher : Indonesian Socety of Obstetrics and Gynecology

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Abstract

Objectives: To compare the expression of tenascin in the anterior vaginal wall in women with pelvic organ prolapse and without pelvic organ prolapse (POP). Method: This study was a cross sectional study. The study was conducted in RS Dr. Wahidin Sudirohusodo and other network hospitals of Obstetrics and Gynecology Department of Hasanuddin University, Makassar, from 1st January 2011 to 1st April 2012. This study assessed the expression of tenascin in 35 women with pelvic organ prolapse grade III and IV and the controls were 35 women without pelvic organ prolapse. Tenascin expression was assessed by immunohistochemical examination using tenascin antibody staining (mouse monoclonal antibody Novacastratenascin C, code NCLTenasC). Sampling was done by consecutive sampling. Data processed by the chi-square. The significance level used was 0.05. Result: The result of this research shows that with exception of history of bearing baby > 4000 gr weight (p=0.572); age, parity, menopausal status, and body mass index were significantly different between the group. This indicates that the variable does not affect the calculation of research data. While parity, menopausal status and body mass index (BMI), from an analysis of risk factors for POP were associated with increased intensity of tenascin is significant in postmenopausal status, and BMI > 25 (overweight) (p
Difference of Vertical Transmission in HIV-Infected Women with Complete and Incomplete PMTCT Fausihar, Sitti; Saroyo, Yudianto B
Indonesian Journal of Obstetrics and Gynecology Volume. 3, no. 2, April 2015
Publisher : Indonesian Socety of Obstetrics and Gynecology

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (128.755 KB) | DOI: 10.32771/inajog.v3i2.30

Abstract

Objective: To analyze any differences on vertical transmission in groups with complete and incomplete program as well as the factors influencing completion. Method: This was a retrospective cohort study performed by data collection from medical records and/or interviews from January 2010 to February 2012. The variables analyzed subject characteristics, applied PMTCT program and risk factors affecting transmission. Result: Seventy-five pregnant women who were HIV-positive were initially recruited, but 21 subjects were excluded due to incomplete medical records. In the first group (n=27) who received complete PMTCT, no vertical transmission was identified, while in the second group (n=27) with incomplete PMTCT, seven children were found to be HIV-positive. Rupture of membrane for more than 4 hours was the only significant risk factor for vertical transmission (p=0.001, RR=64.5, 95% CI=6.14-677.6). Conclusion: There was a significant difference in the occurrence of vertical transmission between complete and incomplete PMTCT program. Complete PMTCT program may provide protective effect against the occurrence of vertical transmission by 25.9%. Keywords: HIV, PMTCT, vertical transmission
Human Papilloma Virus Selftesting as an Alternative Method for Cervical Cancer Screening Chandra, Richard; Rauf, Syahrul; Malinta, Umar
Indonesian Journal of Obstetrics and Gynecology Volume. 5, No. 2, April 2017
Publisher : Indonesian Socety of Obstetrics and Gynecology

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (98.036 KB) | DOI: 10.32771/inajog.v5i2.531

Abstract

Objective: To determine the level of acceptance of self Human Papilloma Virus (HPV) examination and to compare the level of sensitivity and specificity of self HPV examination with Fluid Based Cytology on precancerous cervical lesion and cervical cancer. Methods: The analytical method used in this research was cross sectional with purposive sampling. This study is conducted at Wahidin Sudirohusodo Hospital and its affiliation from October 2014 to May 2015 with 101 subjects. The data measurement used self HPV examination tool and fluid based cytology kit. The data collected through questionnaires before and after the examination. The laboratory examination was carried out using the way of HPV Genotyping primary system (MY09/11) method Wl LTS-06, which is able to detect 35 types of HPV viruses. Results: A total of 101 subjects were involved in this study. The subjects were divided into two groups: the abnormal and normal group (n - 50/51). The acceptance level of self HPV examination was 62.37% (n = 63/101). Majority of subjects (88.21%) were ready to repeat the same examination in the future. The level of sensitivity and specificity for self HPV were (56% (95%CI (41.25 - 70.01%)) vs 98% (95%CI (89.55 - 99.95%)), p=<0.000001, while the level of sensitivity and specificity for fluid based cytology were (40% (95%CI (26.41 - 54.82%)) vs 98% (95%CI (89.35 - 99.95%)), p=0.000002. Conclusion: HPV self-testing is very potential to be used as an alternative method for cervical cancer screening. [Indones J Obstet Gynecol 2017; 5-2: 114-119] Keywords: cervical cancer, cervical cancer screening, human papilloma virus, sensitivity, specificity
The Correlation of Early Initiation of Breastfeeding with Achievement of Exclusive Breastfeeding and Corresponding Factors Tamara, Marina
Indonesian Journal of Obstetrics and Gynecology Volume. 35, No. 4, October 2011
Publisher : Indonesian Socety of Obstetrics and Gynecology

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Abstract

Objective: To study the role of early breastfeeding in time of placental expulsion, breast milk secretion and achievement of exclusive breastfeeding. Method: A prospective cohort study was carried out at Dr. Cipto Mangukusumo General Hospital Jakarta delivery suite in January 2011. Total sample was 68 and divided into 34 sample who was conducting early initiation of breastfeeding and another 34 who did not. Time computation was conducted by the time of placental expulsion and breast milk secretion and also observation within the first 6 month to see whether exclusive breastfeeding was achieved or not. Result: From the study the obtained patients’ characteristic data were 38.2% aged 25-29 years old, 52.9% multiparity, 72.1% having middle education degree (Junior High School to Senior High School graduates), 39.7% on low economic level, and mostly unemployed (73.5%). From total sample, it was found 48 patients (70.6%) who succeded in managing exclusive breastfeeding and 20 patients (29.4%) who did not with 50% stated working as the reason. Conclusion: Early initiation of breastfeeding (EIB) has correlation with duration of placental expulsion, duration of breastmilk secretion and achievement of exclusive breastfeeding. The mean time needed to achieve early initiation of breastfeeding was 46.5 minutes. The mean time of placental expulsion in patient with EIB was 7.35 minute (SD ± 2.695) there was significant correlation between EIB with the time of placental expulsion (p=0.005). The mean time of breastmilk secretion in patient with EIB was 10.65 hours (SD ± 4.947) and there was significant correlation between EIB with the time of breastmilk secretion (p=0.000). It was found significant correlation on data analysis between patients who succeeded to manage EIB with achievement of exclusive breastfeeding (p=0.033). There is also statistically significant correlation between working mothers and achievement of exclusive breastfeeding (p= 0.005) with comparison of probability to have exclusive breastfeeding success rate between unemployed mother and employed mother. Being 1.8 times (RR: 1.800, IK 95% : 1.054-3.073) with cofounding factor is employment status. [Indones J Obstet Gynecol 2011; 35-4: 161-6] Keywords: early initiation of breastfeeding, exclusive breastfeeding, time of placental expulsion, time of breast milk secretion
Korelasi kadar endothelin-1 darah tali pusat dan kerusakan vaskular plasenta pada pertumbuhan janin terhambat WIRMAN, R. M.; WIKNJOSASTRO, G. H.
Indonesian Journal of Obstetrics and Gynecology Volume. 32, No. 3, July 2008
Publisher : Indonesian Socety of Obstetrics and Gynecology

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Abstract

Tujuan: Untuk mengetahui apakah terdapat perbedaan kadar Endothelin- 1 (ET-1) darah tali pusat pada a.Umbilikalis bayi PJT dan normal serta korelasi antara kadar ET-1 dengan kerusakan vaskular plasenta. Tempat: Instalasi Gawat Darurat Obstetri Ginekologi Lantai III RSUPN Dr. Cipto Mangunkusumo, Jakarta. Rancangan/rumusan data: Studi potong lintang. Bahan dan cara kerja: Enam puluh empat subjek, masing-masing 32 orang untuk kelompok kasus (bayi PJT) dan 32 orang kelompok bayi normal dilakukan pemeriksaan kadar ET-1 darah tali pusat (a.Umbilikalis) dengan metoda ELISA dan perbedaan rerata kadar ET-1 tersebut akan diuji secara statistik. Sampel plasenta dari seluruh subjek penelitian dilakukan pemeriksaan histopatologi dan berdasarkan kriteria Salafia. Hasil: Rerata berat lahir bayi pada kelompok PJT lebih rendah dibandingkan rerata kelompok kontrol (1.843 ± 364,4 vs 3.162,5 ± 327,3 gram, p = 0,000). Perbedaan bermakna secara statistik antara kelompok PJT dan kontrol juga diperoleh dari rerata kadar ET-1 8,15 ± 2,7 vs 5,6 ± 1,7 pg/ml, p = 0,000, skor Salafia 6,78 ± 1,7 vs 3,41 ± 1,4, p = 0,000 dan berat plasenta 344,4 ± 81,9 vs 460,16 ± 70,9 gram, p = 0,000. Korelasi antara kadar ET-1 dengan skor Salafia diperoleh nilai p = 0,01 yang berarti terdapat korelasi yang bermakna antara kedua variabel dengan nilai korelasi 0,395, menunjukkan bahwa korelasinya positif dengan kekuatan yang lemah. Antara kadar ET-1 dengan berat lahir bayi terdapat korelasi yang bermakna dengan nilai korelasinya adalah -0,479 menunjukkan korelasi negatif berarti makin tinggi kadar ET-1 makin rendah berat lahir bayi. Kesimpulan: Terdapat perbedaan yang bermakna antara kadar ET-1 darah tali pusat antara bayi PJT dan normal di mana kadar pada PJT lebih tinggi, demikian juga skor Salafia antara kedua kelompok. Ditemukan korelasi positif yang lemah antara kadar ET-1 dan skor Salafia sedangkan antara kadar ET-1 dan berat lahir bayi terdapat korelasi negatif sedang. [Maj Obstet Ginekol Indones 2008; 32-3: 123-30] Kata
Impact of Uterine Prolapse Surgery on Improvement of Bowel Symptoms Zulfadli, Zulfadli
Indonesian Journal of Obstetrics and Gynecology Volume. 2, No. 3, July 2014
Publisher : Indonesian Socety of Obstetrics and Gynecology

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (118.723 KB) | DOI: 10.32771/inajog.v2i3.396

Abstract

Objective: To find the effectiveness of uterine prolapse surgery in patients with bowel symptoms. Method: Clinical trial without comparison study of 32 consecutive women who underwent surgery for grade III and IV uterine prolapse with bowel symptoms. Bowel symptoms score was evaluated before and three months after surgery by using the Australian Pelvic Floor Questionnaire. Data was analyzed using SPSS version 20. Result: There were significant mean differences between bowel symptoms score three months after surgery for grade III and IV uterine prolapse and before surgery although there were patients with persistent symptoms. Bowel symptoms scores include constipation, flatus incontinence, fecal incontinence, fecal urgency, defecation frequency, defecation consistency, incomplete bowel emptying, laxative use, and frequency of defecation disorder score, with p
N/A INAJOG, INAJOG
Indonesian Journal of Obstetrics and Gynecology Volume. 3, No. 4, October 2015
Publisher : Indonesian Socety of Obstetrics and Gynecology

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Abstract

N/A
Relationship between Vaginal Sialidase Levels with Threatened of Preterm Labour Sulistyo, Bambang; Warouw, Najoan N; Suparman, Eddy
Indonesian Journal of Obstetrics and Gynecology Volume 6. No. 1. January 2018
Publisher : Indonesian Socety of Obstetrics and Gynecology

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (97.271 KB) | DOI: 10.32771/inajog.v6i1.753

Abstract

Objective: To investigate the association between vaginalsialidase levels and threatened of preterm labor.Methods: A cross sectional study design was used. Subjects weredivided into two groups; the first group were pregnant women withthreatened of preterm labour, whereas the second were pretermpregnant women in Prof. Dr. R.D. Kandou Manado hospitals andnetwork hospitals, during the period between August 2016 andOctober 2016. Data were analyzed with SPSS version 20 to see thesignificancy levels.Results: From the 16 pregnant women with threatened ofpreterm labor and 16 pregnant women with preterm pregnant,the statistical t test showed that there were significant differencesaverage level of sialidase vagina between the threatened ofpreterm labor and preterm pregnant group (p = 0.000).Conclusion: There is a relationship between the incidencethreatened of preterm labor with vaginal sialidase levels.Keywords: bacteria, threat of preterm labour, vaginal sialidase
Predictive Factors for Pregnancy in IVF: An Analysis of 348 Cycles Wiweko, Budi
Indonesian Journal of Obstetrics and Gynecology Volume. 34, No. 4, October 2010
Publisher : Indonesian Socety of Obstetrics and Gynecology

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Abstract

Objective: To determine predictive factors for pregnancy after IVF. Method: The subject of this study were three hundred and forty eight IVF cycles in 266 couples who underwent controlled ovarian hyperstimulation in IVF cycles between January 2005 and March 2010. Categorical variables were compared using Chi Square test and continuous variables were analyzed using Independent t-test, p < 0.05 was considered statistically significant. Multivariate logistic regression analysis was done to test correlations between clinical variables and the occurrence of pregnancy. Results: The women’s age significantly influenced pregnancy rate since women under 35 years old has the best chance for pregnancy (56.4%). Endometrial thickness on the day of hCG administration also significantly influenced pregnancy in IVF (p < 0.001) because 64.1% of pregnancy occurred if endometrial thickness ≥ 10.95 mm. Serum FSH on 3rd day of period that can predict ovarian reserve also has significance on pregnancy. On the other hand, 61.5% pregnancy occurred if more than 6 mature oocytes were retrieved (p < 0.001). Among 92 patients of 348 cycles we found strong correlation between AMH level with number of mature oocytes retrieved (p < 0.001; r 0.659). Logistic regression done revealed the couple with best chance of pregnancy can be described as follows: women with endometrial thickness ≥ 10.95 mm, number of mature oocytes > 6 and age under 35 years old. Conclusion: This study enabled the characterization of many prognostic factors for pregnancy. [Indones J Obstet Gynecol 2010; 34-4: 180-4] Keywords: in vitro fertilization, clinical pregnancy, age, mature oocytes, endometrial thickness
Analisis polimorfisme gen vascular endothelial growth factor (VEGF) pada endometriosis ABDULLAH, N.
Indonesian Journal of Obstetrics and Gynecology Volume. 33, No. 2, April 2009
Publisher : Indonesian Socety of Obstetrics and Gynecology

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Abstract

Tujuan: Melihat hubungan antara polimorfisme gen VEGF dengan kejadian endometriosis pada pasien yang dilakukan operasi laparoskopi. Tempat: RSUP Dr. Wahidin Sudirohusodo, Makassar. Bahan dan cara kerja: Polimorfisme nukleotida tunggal pada gen VEGF -460 pada daerah promoter dan +405 pada daerah 5’ -untranslated diuji hubungan pada penelitian potong lintang terhadap 50 perempuan dengan endometriosis dan 28 perempuan tanpa endometriosis. Setelah ekstraksi genom DNA, dilakukan pemeriksaan polymerase chain reaction (PCR) dan restriction fragment length polymorphism (RFLP) untuk analisis genotip polimorfisme VEGF. Penelitian ini dilakukan di Makassar-Indonesia sejak Januari 2007 sampai dengan Oktober 2007. Hasil: Distribusi genotip polimorfisme -460T>C pada perempuan dengan endometriosis berbeda bermakna dibandingkan dengan perempuan tanpa endometriosis (pG pada perempuan dengan endometriosis berbeda tidak bermakna dibandingkan dengan perempuan tanpa endometriosis (p>0,05). Kesimpulan: Data ini menunjukkan bahwa polimorfisme nukleotida tunggal pada gen VEGF -460T>C pada daerah promoter gen VEGF bisa berhubungan dengan kejadian endometriosis pada populasi di Makassar- Indonesia. [Maj Obstet Ginekol Indones 2009; 33-2: 108-17] Kata kunci: endometriosis, polimorfisme, VEGF

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