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INDONESIA
Indonesian Journal of Obstetrics and Gynecology (Majalah Obstetri dan Ginekologi Indonesia)
Published by Perkumpulan Obstetri dan Ginekologi Indonesia
ISSN : 23386401     EISSN : 23387335     DOI : -
Core Subject : Health,
Health Professions Medicine & Pharmacology Public Health
The Indonesian Journal of Obstetrics and Gynecology is an official publication of the Indonesian Society of Obstetrics and Gynekology. INAJOG is published quarterly.
Arjuna Subject : -
Articles 1,760 Documents
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Perbandingan efektivitas dan keluhan efek samping pada penggunaan Dioktil Sodium Sulfosuksinat (DSS)-Sorbitol dan Klisma Gliserin untuk persiapan pra-operasi di Departemen Obstetri dan Ginekologi RSUPN Dr. Cipto Mangunkusumo VALLERIA, VALLERIA; SANTOSO, B. I.; JUNIZAF, JUNIZAF
Indonesian Journal of Obstetrics and Gynecology Volume. 32, No. 1, January 2008
Publisher : Indonesian Socety of Obstetrics and Gynecology

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Abstract

Tujuan: Untuk mengetahui perbandingan antara pemakaian DSSSorbitol dengan klisma gliserin untuk persiapan pra-operasi dalam hal efektivitas, kenyamanan dan keluhan (efek samping) yang ditimbulkan keduanya. Rancangan/rumusan data: Uji klinis tersamar tunggal. Bahan dan cara kerja: Penelitian ini dimulai pada tanggal 1 April 2006 selama 6 bulan, dilakukan pada 180 orang pasien yang akan menjalani pembedahan elektif di departemen obstetri dan ginekologi RSCM, dibagi atas 2 kelompok yaitu kelompok yang diberi DSS-Sorbitol (90 orang) dan kelompok yang dilakukan klisma gliserin (90 orang). Pengambilan sampel dilakukan secara random. Setelah perlakuan, pasien ditanyakan keluhannya dan dicatat pada kuesioner kemudian selama operasi berlangsung dilakukan pengamatan dan pencatatan apakah ada feses yang keluar di meja operasi. Hasil: Pada kelompok gliserin didapatkan 3 pasien (3,3%) keluar feses saat operasi sedangkan pada kelompok DSS-Sorbitol didapatkan 1 pasien (1,1%). Tidak terdapat perbedaan bermakna antara kedua kelompok. Hampir sebagian besar pasien merasa nyaman dengan pemberian DSS-Sorbitol (81 orang) hanya 9 orang yang menyatakan tidak nyaman. Sedangkan pada kelompok gliserin terdapat 30 orang yang merasa tidak nyaman dan perbedaan ini sangat bermakna {p = 0.000; OR = 4.50 (1.99 - 10.18)}. Terdapat 58 pasien (32,2%) yang mengeluh saat dilakukan klisma atau pemberian DSS-Sorbitol dengan 9 orang diantaranya mempunyai keluhan lebih dari satu (8 orang dari kelompok gliserin dan 1 orang dari kelompok DSS-Sorbitol). Dari 58 pasien tersebut, 42 orang di antaranya diberikan gliserin (46,7%) dan sisanya, 16 orang diberikan DSS-Sorbitol (17,8%). Keluhan yang paling banyak adalah mulas, dikeluhkan oleh 40 pasien dari kelompok gliserin dan 10 pasien dari kelompok DSS-Sorbitol. Keluhan yang lain adalah mual (2 dari kelompok DSS-Sorbitol, 1 dari kelompok gliserin), pusing (2 dari kelompok DSS-Sorbitol, 1 dari kelompok gliserin), dan feses tidak keluar (1 dari kelompok DSS-Sorbitol, 3 dari kelompok gliserin) ditemukan pada kedua kelompok sedangkan keluhan kembung (3 orang), feses berdarah (3 orang) dan alat panas (1 orang) hanya ditemukan pada kelompok gliserin. Sebanyak 114 pasien menyatakan bersedia untuk diulangi persiapan pra-operasi pembersihan rektum ini, dengan proporsi lebih banyak yang bersedia dari kelompok DSS-Sorbitol, tetapi perbedaan tersebut tidak bermakna. Dari perhitungan statistik ternyata kesediaan pasien untuk diberikan kembali klisma gliserin atau DSS-Sorbitol sangat dipengaruhi oleh rasa nyaman dan keluhan yang ditimbulkan oleh masingmasing cara. Kesimpulan: Pemakaian klisma gliserin sama efektifnya dengan pemberian DSS-Sorbitol, namun pemberian DSS-Sorbitol lebih nyaman dan menimbulkan keluhan yang lebih sedikit. [Maj Obstet Ginekol Indones 2008; 32-1: 55-62] Kata kunci: DSS-Sorbitol, gliserin, persiapan pra-operasi
Length of Menopause has a Positive Correlation with C-Telopeptide Plasma Level in Pascamenopause Women Pangestu, Willy
Indonesian Journal of Obstetrics and Gynecology Volume. 2, No. 1, January 2014
Publisher : Indonesian Socety of Obstetrics and Gynecology

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Abstract

Objective: To determine the correlation between length of menopause with C-telopeptide in pascamenopause women. Method: An analytic cross-sectional study of 29 pascamenopause women in Malalayang hospital Manado. Sampling method with consecutive random sampling. Data were analyzed with Spearman test with significance level of p
Serum Zinc Level at Term Pregnancy and Newborn Anthropometry Seriana, Irma; Yusrawati, Yusrawati; Lubis, Gustina
Indonesian Journal of Obstetrics and Gynecology Volume. 3, No. 4, October 2015
Publisher : Indonesian Socety of Obstetrics and Gynecology

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (131.719 KB) | DOI: 10.32771/inajog.v3i4.53

Abstract

Objective: To determine the relationship between serum zinc level at term pregnancy and newborn anthropometry. Methods: This study is an observational study with cross-sectional design. Serum zinc level at term pregnancy was measured and then anthropometric measurement was done to the newborn, including birth weight, birth length and head circumference at birth. The data were statistically analyzed using regression correlation test. Results: Mean serum zinc level at term pregnancy is 36.01 μg/dl (SD=18.34 μg/dl), the average birth weight is 3158 gr (SD=480.4 gr), the average birth length is 48.42 cm (SD=1.75 cm) and the average head circumference at birth is 33.13 cm (SD=1.14 cm). There was no statistically significant relationship between serum zinc levels at term pregnancy and birth weight (p-value=0.152). Meanwhile, there are statistically significant relationships between serum zinc level at term pregnancy with birth length and head circumference with pvalue 0.026 and 0.012, respectively. Conclusion: Serum zinc level at term pregnancy is correlated with birth length and head circumference, but is not correlated with birth weight. [Indones J Obstet Gynecol 2015; 3-4: 190-195] Keywords: birth length, birth weight, head circumference at birth, serum zinc level, term pregnancy
Multiple Factors Affecting Length of Hospital Postpartal Care in Eclampsia Patients Dianty, Gita
Indonesian Journal of Obstetrics and Gynecology Volume. 36, No. 2, April 2012
Publisher : Indonesian Socety of Obstetrics and Gynecology

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Abstract

Objective: To identify any factors that could cause longer care at hospitals in eclampsia patients. Methods: It was a retrospective, cross sectional study design and conducted in Dr. Mohammad Hoesin Hospital Palembang from January 2005 to December 2009. This research conducted in 176 samples divided into 2 groups namely short-stay group (1-5 days) with 92 patients and longer stay group (≥ 5 days) with 87 patients, with mean length of hospital stay 5.41±3.43 days. Results: The most common mode of delivery in the group who stayed ≥ 5 days was cesarean section (44.8%), while the most common delivery route in the group who stayed < 5 days was forceps extraction (43.5%). The mean thrombocytes count in the longer stay group was lower than in the short-stay group (213459.77±108391.81 vs 258945.65±92213.24 mm3), which was significantly different (p=0.003). Ureum and LDH concentration in longer stay group was higher, and statistic test was found to be significantly different (p
Peningkatan kadar soluble Vascular Cell Adhesion Molecule-1 (sVCAM-1) sebagai petanda aktivasi endotel pada serum penderita sindrom antifosfolipid yang dipajankan pada kultur endotel tali pusat manusia PRATAMA, G.
Indonesian Journal of Obstetrics and Gynecology Volume. 33, No. 1, January 2009
Publisher : Indonesian Socety of Obstetrics and Gynecology

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Abstract

Tujuan: Mendapatkan kadar soluble VCAM-1 (sVCAM-1) pada serum penderita APS yang dipajankan pada kultur sel endotel vena umbilikalis manusia untuk membuktikan adanya peran aktivasi endotel pada mekanisme terjadinya trombosis pada penderita APS (antiphospholipid syndrome). Bahan dan cara kerja: Penelitian eksperimental laboratorium secara in vitro di Makmal Terpadu Imuno-Endokrinologi/FKUI pada tahun 2003. Sebanyak masing-masing 14 sampel serum yang berasal dari pasien APS dan non APS yang memenuhi kriteria inklusi dan eksklusi berdasarkan batasan operasional (kriteria Sapporo). Kemudian kultur sel endotel dipajankan selama 24 jam dengan medium perlakuan yang ditambahkan 20 % serum dari masing-masing penderita APS atau non APS. Kemudian diukur kadar sVCAM-1 pada masing-masing sampel dengan metode enzyme-linked immunosorbent assay (ELISA). Hasil: Secara statistik didapatkan perbedaan bermakna (p < 0,05) antara kadar sVCAM-pada serum APS dibandingkan dengan serum non APS yang tidak dipajankan pada kultur sel endotel vena umbilikalis manusia. Secara statistik juga didapatkan perbedaan bermakna (p < 0,05) pada kadar sVCAM-1 pada serum APS dibandingkan dengan serum non APS setelah dipajankan pada kultur sel endotel vena umbilikalis manusia selama 24 jam per 10.000 sel endotel. Kesimpulan: Produksi sVCAM-1 oleh sel endotel vena umbilikalis manusia yang dipajankan dengan serum APS lebih tinggi daripada yang dipajankan dengan serum non APS. Kadar sVCAM-1 pada serum APS yang tidak dipajankan pada kultur sel endotel vena umbilikalis manusia didapatkan lebih tinggi daripada serum non APS yang tidak dipajankan pada kultur sel endotel vena umbilikalis manusia. [Maj Obstet Ginekol Indones 2009; 33-1: 35-40] Kata kunci: soluble VCAM-1 (sVCAM-1); APS (Antifosfolipid sindrom); Kriteria Sapporo; ELISA (Enzyme Linked Immunosorbent Assay)
Profile of Estrogen Metabolism in Endometriosis Patients Verani, Tirsa
Indonesian Journal of Obstetrics and Gynecology Volume. 2, No. 3, July 2014
Publisher : Indonesian Socety of Obstetrics and Gynecology

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Abstract

Objective: To assess the estrone (E1), estradiol (E2) and estriol (E3) blood level and its ratio (E2:E1, E2:E3 and E1:E3) between women with and without endometriosis. Method: We performed an analytical cross sectional study with 27 women with endometriosis and 27 women without endometriosis who met the inclusion criteria. The samples were recruited in Dr. Cipto Mangunkusumo hospital and other satellite hospitals from October 2012 to April 2013. The blood level of estrogen metabolites was examined by enzyme-linked immunosorbent assay (ELISA). Comparison between the two groups was analyzed by using Mann-Whitney test. Result: The level of estrone was found to be lower in endometriosis group compared to that in the control group (54.66 pg/ml vs 73.52 pg/ml, p=0.229). Similarly, the levels of estradiol and estriol were lower in endometriosis group (29 pg/ml vs 35 pg/ml, p=0.815 and 1.11 pg/ml vs 1.67 pg/ml, p=0.095, consecutively). The E2:E1 ratio was higher in endometriosis group (0.51 pg/ml vs 0.38 pg/ml, p=0.164), as well as E2:E3 ratio (26.53 pg/ml vs 21.11 pg/ml, p=0.223) and the E1:E3 ratio (58.55 pg/ml vs 50.28 pg/ml, p=0.684). However, all those differences were not statistically significant. Conclusion: The estrone, estradiol and estriol levels in women with endometriosis were lower compared to those in women without endometriosis. The ratio of E2:E1, E2:E3 and E1:E3 were higher in endometriosis group. However, all those differences failed to reach statistical significance. [Indones J Obstet Gynecol 2014; 3: 127-131] Keywords: endometriosis, estradiol, estriol, estrogen, estrone
Diabetes Mellitus and Hypertension are Risk Factor for Endometrial Cancer Wijaya, Chresni F.
Indonesian Journal of Obstetrics and Gynecology Volume. 36, No. 3, July 2012
Publisher : Indonesian Socety of Obstetrics and Gynecology

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Abstract

Objective: To find out whether diabetes mellitus and/or hypertension is associated with endometrial cancer and could increase the staging of the cancer. Method: This was an analytic retrospective descriptive study with cross sectional design. Data were taken from the medical record of patients diagnosed as having endometrial cancer in Obstetrics and Gynecology Department of Dr. Hasan Sadikin Hospital from 1st January 2007 - 31st December 2011 and analyzed descriptively. Result: There were 125 cases of endometrial cancer. Prevalence was 2.56 %. The incidence increased in age > 40 y/o (92 %) and had diabetes mellitus and/or hypertension (66.4 %). Conclusion: Diabetes mellitus and/or hypertension were associated with risk factors of endometrial cancer but not proven to increase the staging of the cancer. [Indones J Obstet Gynecol 2012; 36-3: 140-3] Keywords: diabetes mellitus, endometrial cancer, hypertension
Serum Anti Mullerian Hormone level as ovarium response predictor at women received ovarium stimulation invitro Soebijanto, Soegiharto
Indonesian Journal of Obstetrics and Gynecology Volume. 33. No. 4, October 2009
Publisher : Indonesian Socety of Obstetrics and Gynecology

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Abstract

Objective: To evaluate clinical value of basal anti-Mullerian Hormone level as predictor of ovarian response to stimulation in women following in vitro fertilization program; compared with Follicle Stimulating Hormone (FSH), estradiol and basal antral follicle. Method: Research was conducted in Yasmin Clinic Cipto Mangunkusumo Hospital as tertiary referral center for reproductive health and in vitro fertilization. Infertile patients which going to undergo controlled ovarian hyper stimulation cycle for in vitro fertilization were checked for basal FSH level, estradiol level, AMH level and amount of basal antral follicle. We were divided the sample into two categories; poor responders and good responders. Statistical analysis using ANOVA was done to evaluate demographic data and Receiver Operator Characteristic area under curve (ROCAUC), and to analyze whether AMH was more superior than the other 3 predictors and to get the cut off point for AMH level. Result: We have collected 22 patients data; 14 were categorized as good responders and 8 were bad responders. Mean AMH value in the good responders group was 4.46±1,01 and in the poor responders group was 1,35±0,96, with p 0,000. According to ROCAUC, AMH is a good predictor for good ovarian response in patient who are a good responders (AUC 0,821), compared to the other three predictors (FSH, E2 and basal antral follicle). Anti Mullerian Hormone cut-off point level is 3, which means value
Characteristics of Patients with Obstetric and Gynecologic Fistula in Jakarta Djusad, Suskhan; Sonia, Ambalagen; Natanael, Anthonyus
Indonesian Journal of Obstetrics and Gynecology Volume 4, No. 4, October 2016
Publisher : Indonesian Socety of Obstetrics and Gynecology

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (103.699 KB) | DOI: 10.32771/inajog.v4i4.451

Abstract

Objective: To know the characteristics of patients with obstetrics and gynecologic fistula in Dr. Cipto Mangunkusumo Hospital, Jakarta. Method: This study was a descriptive design using secondary data from medical records and patient database during 2011-2016. Result: There were 68 subjects with fistula. From 2011-2016, there were 5 cases (7.4%), 19 cases (27.9%), 16 cases (23.5%), 11 cases (16.2%), 8 cases (11.8%), and 9 cases (13.2%) of fistula; respectively. The average age of subjects was 38 years old and only 34 subjects have complete data. Gynecologic and obstetric fistula were 17 cases each. As total 28% of fistula cases were vesicovagina fistula, 12% were rectovaginal fistula, 9% were anovagina fistula, and the other types of fistula were 2%. Among 34 subjects, there were 21% of vesicovagina fistula and 3% of rectovagina fistula, which were caused by iatrogenic. There were 7% of vesicovagina and rectovagina fistula each and 9% of anovagina fistula were caused by obstetric problems. The iatrogenic procedures found from this study were total abdominal hysterectomy (16%), vaginal hysterectomy (3%), and neovagina (3%). Conclusion: The trend of cases is decreasing during the present years (2011-2016). Gynecologic fistula cases caused by iatrogenic are the major problems, but the obstetrics fistula cases decreasing following the labor monitoring is much better nowadays. [Indones J Obstet Gynecol 2016; 4-4: 212-217] Keywords: gynecologic fistula, iatrogenic, obstetric fistula
Hubungan antara Penyakit Radang Panggul Asimptomatik dengan Ekspresi Integrin αvβ3 Endometrium Fase Luteal Madya pada Wanita Infertil PRASOJO, S. D.; HESTIANTORO, A.; SURJANA, E.; INDARTI, J.; KUSUMA, F.; ENDARDJO, S.
Indonesian Journal of Obstetrics and Gynecology Volume. 30, No. 4, October 2006
Publisher : Indonesian Socety of Obstetrics and Gynecology

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Abstract

Tujuan: Mengetahui gambaran integrin αvβ3 endometrium wanita infertilitas dan kaitannya dengan penyakit radang panggul (PRP) asimptomatik pada saat fase luteal madya. Rancangan: Penelitian kuantitatif dengan rancangan penelitian potong lintang. Bahan dan cara kerja: Penelitian dilakukan pada 32 orang pasien infertilitas yang datang ke klinik Yasmin RSCM kemudian dilakukan biopsi endometrium pada hari ke 19 - 21 dan pemeriksaan progesteron hari ke 21 siklus haid. Hasil biopsi dianalisa untuk dating endometrium, pemeriksaan imunohistokimia di Makmal terpadu RSCM - FKUI (Hasil pewarnaan dievaluasi untuk mendapatkan HSCORE) dan untuk penilaian endometritis histologik di Laboratorium Patologi FKUI. Hasil: Dari 32 sampel biopsi endometrium didapatkan ekspresi integrin αvβ3: (25%) dengan intensitas lemah, (50%) dengan intesitas sedang dan (25%) dengan intesitasnya kuat. Pada 16 (50%) sampel terbukti endometritis dengan 15 (93,8%) sampel ekspresi integrin αvβ3 endometrium adalah lemah - sedang dan 1 (6,3%) sampel ekspresi integrin αvβ3 endometrium adalah kuat, pada uji t tidak berpasangan didapatkan nilai t = -2,631; df = 30 dan nilai p = 0,013. Kesimpulan: Endometritis pada wanita infertilitas dengan PRP asimtomatik, mungkin memiliki hubungan dengan lemahnya ekspresi αvβ3 integrin endometrium pada populasi infertilitas wanita. [Maj Obstet Ginekol Indones 2006; 30-4: 229-33] Kata kunci: integrin αvβ3 endometrium, Penyakit radang panggul (PRP) asimptomatik, Infertilitas, Fase luteal madya

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