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INDONESIA
ISM (Intisari Sains Medis) : Jurnal Kedokteran
Published by Universitas Udayana
ISSN : 25033638     EISSN : -     DOI : -
Core Subject : Health, Science,
Intisari Sains Medis is published by Medical Scientific Community, Indonesia. Intisari Sains Medis is an international, multidisciplinary, peer-reviewed, open access journal accepts papers for publication in all aspects of Science Digest, Medical Research Development, Research Medical Field and Theory. We also publish cases from third world country, that is considered very rare and special cases.
Arjuna Subject : -
Articles 1,063 Documents
The characteristics of preeclampsia among patients delivered through caesarean section at Sanglah General Hospital, Denpasar, Bali in 2018 Anindita Pramanik; Ida Bagus Gede Fajar Manuaba; Anak Agung Putra Wiradnyana
Intisari Sains Medis Vol. 10 No. 3 (2019): (Available online: 1 December 2019)
Publisher : DiscoverSys Inc.

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (272.078 KB) | DOI: 10.15562/ism.v10i3.478

Abstract

Background: Preeclampsia is an exclusive disorder in pregnancy characterised by hypertension as well as proteinuria and is the primary cause of mortality and morbidity of pregnant women. This study aims to determine the characteristics or risk factors in preeclampsia patients who delivered through caesarean section within the period of January 1st to December 31st 2018 in Sanglah General Hospital Denpasar.Methods: This study used a retrospective descriptive study design by using 34 samples of preeclampsia patients in 2018 who underwent caesarean delivery in Sanglah General Hospital Denpasar. The characteristics of these pregnant women are categorized into their age, education level, Body Mass Index (BMI), ethnicity, occupation, education level, previous history of preeclampsia, family history of preeclampsia, existing chronic hypertension, parity, number of fetus in womb, frequency of Antenatal Care (ANC), and registration method. Data were analysed by SPSS version 17 for windows.Results: The preeclampsia sufferers were dominated by the age group of 20-35 years as many as 27 people (79.4%). The highest body mass index is in the 1 obese group of 10 people (29.4%). The majority of respondents were from Bali (61.8%). Working women were predominant (67.6 %), followed by SMA education level (14.7%), existing chronic hypertension (5.9%), nulliparous (41.1%), single fetuses (94.1%), and total frequency of ANC to midwife/obstetrician consisting about 61.8%.Conclusion: It can be concluded that the majority of the patients were in the age range of 20-35 years, were Balinese and had a BMI range of Obese I. Moreover, most the preeclampsia patients in this study were working women and had an education level mostly in SMA
The level of knowledge and attitude towards dengue fever among medical students of Udayana University, Bali, Indonesia in 2018 Agilan Sethupathy; I Made Sudarmaja; Luh Ariwati
Intisari Sains Medis Vol. 10 No. 3 (2019): (Available online: 1 December 2019)
Publisher : DiscoverSys Inc.

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (260.129 KB) | DOI: 10.15562/ism.v10i3.479

Abstract

Background: There is a lot of impact of dengue among youngsters and also adults. The virus infects human blood and causes a migraine-like headache, rash, achiness, queasiness, tiredness and fever. Severe dengue can cause organ damage, severe bleeding, dehydration and even death. So, this study aims to know the level of knowledge and attitudes towards dengue infection among medical students from Faculty of Medicine, Universitas Udayana, Bali, IndonesiaMethods: A cross-sectional study was conducted among 99 respondents by using a valid and reliable self-questionnaires to assess the participants‘ knowledge and attitude about dengue fever. Knowledge is the ability to answer correctly towards Dengue related questions. Knowledge was evaluated based on 20 questions grouped under the following three categories. The attitude was assessed based on the ability of participants to give correct answers to 14 questions on attitude towards dengue. After that, the data were analysed using SAS software package version 9.1.Results: There was 43% were men and 56% of women enrolled in this study. Most of them are aged 18 years old (69.7%), followed by 19 years old (23.2%), and 17 years old (6.1%). The average age was 18.15 + 0.5 years old. All of the participants (100%) answered that they would go to the doctor they get the dengue infection. Around 94,9% of them stated that they would drink a lot of water if they get dengue fever, and 89,9% of them said they would get a lot of rest. The vast majority of participants use insecticide (86,9%), curtains (84,8%), mosquitoes net (81,8%), cover their water storage (98,0%) and try to not hoard stuff in their home (90,9%).Conclusion: The recent findings suggest that most students know the symptoms, transmission, and how to manage dengue fever. The attitudes of participants toward dengue infection have been assessed, and all answered that they would go to the doctor if they get the dengue infection
The prevalence of panic disorder among English Class students at Medical Faculty, Universitas Udayana, Bali, Indonesia in 2018 Thevarani Ramachandran; Ida Ayu Kusuma Wardani; Lely Setyawati
Intisari Sains Medis Vol. 10 No. 3 (2019): (Available online: 1 December 2019)
Publisher : DiscoverSys Inc.

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (241.648 KB) | DOI: 10.15562/ism.v10i3.480

Abstract

Background: Panic disorder is diagnosed in people who experience spontaneous, seemingly out-of-the-blue panic attacks and are very preoccupied with the fear of a recurring attack. Panic disorder usually begins in adulthood (after age 20) and can interfere a lot with daily life, causing people to miss work, go to many doctor visits, and avoid situations where they fear they might experience a panic attack. This study aims to determine the prevalence of panic disorder among English Class students at Medical Faculty, Universitas Udayana, Bali, Indonesia in 2018Methods: An observational cross-sectional study was conducted among 89 medical students from English Class at the Faculty of Medicine, Universitas Udayana in 2018 using total sampling techniques. A self-administered questionnaire was carried out to determine the prevalence of panic disorder by several valid and reliable questions. Data were analysed using SPSS version 20 for Windows and presented in frequency and percentage.Results:  Most of the respondents were 20 years old (57.3%). There are only 12.0% of English class Semester 7 students are free from panic disorder, 51.0% suffers from mild panic disorder, and 37.0% suffers from moderate panic disorder. Around 64% of female respondents have panic disorder while 34% in male respondents. Female respondents are tended to get more panic attacks than male respondents in a ratio of 2:1.Conclusion: Female medical students tend to have a higher risk of panic disorder compared with males. The majority age of students suffering from panic attacks is from 20 to 23 years old.
Analisis faktor risiko bayi Berat Badan Lahir Rendah (BBLR) di Unit Pelayanan Terpadu (UPT) Kesehatan Masyarakat (Kesmas) Gianyar I tahun 2016-2017 Padma Permana; Gede Bagus Rawida Wijaya
Intisari Sains Medis Vol. 10 No. 3 (2019): (Available online: 1 December 2019)
Publisher : DiscoverSys Inc.

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (273.223 KB) | DOI: 10.15562/ism.v10i3.481

Abstract

Background: One of the major causes of newborn mortality is Low Birth Weight (LBW). Each year estimated 15% to 20% of world births or more than 20 million babies are LBW. In UPT Kesmas Gianyar I, there is an increasing trend of LBW incidence from 2014 to June 2017. So, this study aims to determine several risk factors associated with LBW at UPT Kesmas Gianyar I during 2016-2017 period.Methods: A case-control analytic study was conducted among case group of LBW mothers and control group of mothers with normal weight babies in 2017. Selection technique of case group done by total sampling method, while control group by simple random sampling. Data were analysed using SPSS version 21 for Windows and showing in odds ratio, percentage, and p-value.Results: A total of 106 respondens were enrolled in this study whereas each group consists of 53 patients. There was no significant relationship between mother’s age, number of parity, anemia status, nutritional status, and distance of pregnancy with low birth weight incidence (P>0.05). However, multiple pregnancy has shown a significant relationship with LBW (OR: 14.9; 95%CI 3.2-68.5; P=0.0001) as well as gestational age (OR: 3.1; 95% CI 1.02-9.50; P=0.038). Conclusion: Mothers with multiple pregnancies have a 14.9 times risk of having a baby LBW as well as a premature gestational age also have a 3.1 times higher risk of delivering LBW infants.
Hubungan kadar gula darah dengan hipertensi pada pasien diabetes mellitus tipe 2 di RSUP Sanglah I Dewa Gede Indra Pratama Putra; Ida Ayu Putri Wirawati; Ni Nyoman Mahartini
Intisari Sains Medis Vol. 10 No. 3 (2019): (Available online: 1 December 2019)
Publisher : DiscoverSys Inc.

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (242.721 KB) | DOI: 10.15562/ism.v10i3.482

Abstract

Background: Diabetes mellitus is a metabolic disease with a large number of cases and is characterized by conditions of hyperglycemia that occur due to abnormal insulin secretion, insulin action or both. One of the complications of diabetes is a stroke caused by hypertension. Therefore, this study aims to determine the relationship of blood sugar levels with hypertension in patients with type 2 diabetes mellitus at Sanglah General Hospital.Methods: This study used observational analytic research with a cross-sectional approach. The subjects in this study were patients with type 2 diabetes mellitus who entered the inclusion and exclusion criteria. The instrument used was a mercury meter to measure blood pressure, as well as medical record data to see blood glucose levels. Data obtained were analyzed using SPSS v. 22 to carry out the Pearson correlation test with a significance value of p <0.05. Results: 45 respondents enrolled in this study, with an average age of 64.38 ± 9.719 years. Age 60 - 80 years (55.6%) and women (51.1%) were dominant in this study. Obtained respondents with conditions of hyperglycemia as much as 17.8% and experiencing stage 1 hypertension of 66.7% and stage 2 hypertension of 33.3%. The results of hypothesis testing with Pearson correlation test obtained r= -0.532 and p = 0.041 on systolic blood pressure and r = -0.535 and p = 0.040 on diastolic blood pressure (p <0.05).Conclusions: There is a correlation between blood glucose levels with hypertension in patients with type 2 diabetes mellitus.Latar Belakang: Diabetes mellitus merupakan suatu penyakit metabolik dengan jumlah kasus yang besar serta ditandai dengan kondisi hiperglikemia yang terjadi karena kelainan sekresi insulin, kerja insulin atau kedua-duanya. Salah satu komplikasi dari diabetes adalah stroke yang disebabkan oleh hipertensi. Penelitian ini bertujuan untuk mengetahui hubungan kadar gula darah dengan hipertensi pada penderita diabetes mellitus tipe 2 di RSUP Sanglah.Metode: Penelitian ini menggunakan penelitian observasional analitik dengan pendekatan secara cross-sectional. Subjek dalam penelitian ini adalah pasien diabates mellitus tipe 2 yang masuk kriteria inklusi dan eksklusi. Instrumen yang digunakan adalah tensi meter air raksa untuk mengukur tekanan darah, serta data rekam medik untuk melihat kadar glukosa darah. Data yang diperoleh di analisis menggunakan SPSS v. 22 untuk dilakukan uji korelasi pearson dengan nilai signifikansi p < 0,05. Hasil: 45 responden ikut serta dalam penelitian ini, dengan rerata usia 64,38 ± 9,719 tahun. Usia 60 – 80 tahun (55,6%) dan perempuan (51,1%) dominan dalam penelitian ini. Diperoleh responden dengan kondisi hiperglikemia sebanyak 17,8% dan mengalami hipertensi tahap 1 sebesar 66,7% serta hipertensi tahap 2 sebesar 33,3%. Hasil uji hipotesis dengan uji korelasi pearson diperoleh r= -0,532 dan p= 0,041 pada tekanan darah sistolik dan r= -0,535 dan p= 0,040 pada tekanan darah diastolik (p< 0,05).Simpulan: Terdapat hubungan antara kadar gula darah dengan hipertensi pada penderita diabetes mellitus tipe 2.
Pengaruh ekstrak kulit buah naga merah (Hylocereus polyrhizus) terhadap kadar malondialdehyde liver pada tikus yang diberi paparan asap rokok Melita Soares Cristovao; IGN Sri Wiryawan; I Wayan Sugiritama
Intisari Sains Medis Vol. 10 No. 3 (2019): (Available online: 1 December 2019)
Publisher : DiscoverSys Inc.

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (292.244 KB) | DOI: 10.15562/ism.v10i3.483

Abstract

Background: Peel of red dragon fruit (Hylocereus Polyrhizus) is rarely utilized which is usually just thrown away, even though it contains such high antioxidants such as phenols, flavonoids and also anthocyanins.Methods: This study aims to determine the effect of red dragon fruit skin extract (Hylocereus Polyrhizus) on MDA levels of the liver in rats exposed to cigarette smoke. This research is an experimental study with Post-Test Only Control Group Design. The sample consisted of 30 rats aged 3-4 months which were divided into 5 groups each amounting to 6 rats, namely 1 negative control group was not given exposure to cigarette smoke, 1 group of negative cock was exposed to cigarette smoke, 3 treatment groups were given exposure cigarette smoke and administration of red dragon fruit skin extract with doses of 20mg, 40mh, and 80mg for 14 days. The parameters measured were MDA levels of the liver.Results: mean liver MDA level of control group 1 was 3.14 ± 0.15nmol / ml, mean control group 2 was 3.84 ± 0.88 nmol / ml, mean treatment group 1 was 3.78 ± 0.28nmol / ml, group treatment 2 was 3.37 ± 0.69nmol / ml, and treatment group 3 was 3.05 ± 0.50nmol / ml. Significance analysis with One Way ANOVA test shows that the value of F = 2.127 and the value of p = 0.107, where the value of p> 0.05Conclusion: There was no effect of red dragon fruit skin extract (Hylocereus Polyrhizus) on MDA levels in the liver exposed to cigarette smoke.Latar Belakang: Kulit buah naga merah (Hylocereus Polyrhizus) merupakan limbah yang sangat jarang dimanfatkaan, biasanya kulit buah naga merah hanya dibuang begitu saja, padalah mengandung antioksidan yang begitu tinggi seperti fenol, flavonoid dan juga antiosianin.Metode: Penelitian ini bertujuan untuk mengetahui pengaruh ekstrak kulit buah naga merah (Hylocereus Polyrhizus) terhadap kadar MDA liver pada tikus yang dipaparkan asap rokok. Penelitian ini merupakan penelitian eksperimental dengan Post-Test Only Control Group Design. Sampel terdiri dari 30 ekor tikus yang berumur 3-4 bulan yang dibagi menjadi 5 kelompok masing-masing berjumlah 6 ekor tikus, yaitu 1 kelompok kontrol negative tidak diberikan paparan asap rokok, 1 kelompok kontol negative diberikan paparan asap rokok, 3 kelompok perlakuan diberikan paparan asap rokok dan pemberian ekstrak kulit buah naga merah dengan dosis 20mg, 40mg dan 80mg selama 14 hari. Parameter yang diukur adalah kadar MDA liver. Hasil: rerata kadar MDA liver kelompok kontrol 1 adalah 3,14 ± 0,15nmol/ml, rerata kelompok kontrol 2 adalah 3,84 ± 0,88 nmol/ml, rerata kelompok perlakuan 1 adalah 3,78 ± 0,28nmol/ml, kelompok perlakuan 2 adalah 3,37 ± 0,69nmol/ml, dan kelompok perlakuan 3 adalah 3,05 ± 0,50nmol/ml. Analisis kemaknaan dengan uji One Way Anova menunjukan bahwa nilai F= 2,127 dan nilai p= 0,107, dimana nilai p>0,05Simpulan: Tidak ada pengaruh ekstrak kulit buah naga merah (Hylocereus Polyrhizus) terhadap kadar MDA liver pada tikus yang dipaparkan asap rokok.
Pengaruh ekstrak kulit buah naga merah (Hylocereus polyrhizus) terhadap kadar malondialdehyde (MDA) Paru pada tikus yang diberi paparan asap rokok Raditya Pradipta; IGN Sri Wiryawan; I Wayan Sugiritama
Intisari Sains Medis Vol. 10 No. 3 (2019): (Available online: 1 December 2019)
Publisher : DiscoverSys Inc.

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (286.168 KB) | DOI: 10.15562/ism.v10i3.484

Abstract

Background: Peel of a red dragon fruit (Hylocereus Polyrhizus) is rarely utilized which is usually just thrown way, even though it contains such high antioxidants such as phenols, flavonoids and also anthocyanins.Methods: This study aims to determine the effect of red dragon fruit skin extract (Hylocereus Polyrhizus) on MDA levels of lung in rats exposed to cigarette smoke. This research is an experimental study with Post-Test Only Control Group Design. The sample consisted of 30 rats aged 2-3 months which were divided into 5 groups each amounting to 6 rats, namely 1 negative control group was not given exposure to cigarette smoke, 1 group of positive cock was exposed to cigarette smoke, 3 treatment groups were given exposure cigarette smoke and administration of red dragon fruit skin extract with doses of 20mg, 40mh and 80mg for 14 days. The parameters measured were MDA levels of the lung.Results: The mean MDA level of lung control group 1 was 0.146 ± 0.02 nmol / ml, the mean of control group 2 was 0.166 ± 0.01 nmol / ml, the mean of treatment group 1 was 0.168 ± 0.03 nmol / ml, treatment group 2 was 0.153 ± 0.02 nmol / ml, and treatment group 3 was 0.776 ± 0.09 nmol / ml. The significance analysis with the One Way Anova test shows that the value of F = 1.34 and the value of p = 0.282, where the value of p> 0.05Conclusion: There was no significant difference between the control group and the treatment group or between treatment group 1, treatment 2 and treatment 3. Latar Belakang: Kulit buah naga merah (Hylocereus Polyrhizus) merupakan limbah yang sangat jarang dimanfaatkan, biasanya kulit buah naga merah hanya dibuang begitu saja, padalah mengandung antioksidan yang begitu tinggi seperti fenol, flavonoid dan juga antiosianin.Metode: Penelitian ini bertujuan untuk mengetahui pengaruh ekstrak kulit buah naga merah (Hylocereus Polyrhizus) terhadap kadar MDA paru pada tikus yang dipaparkan asap rokok. Penelitian ini merupakan penelitian eksperimental dengan Post-Test Only Control Group Design. Sampel terdiri dari 30 ekor tikus yang berumur 2-3 bulan yang dibagi menjadi 5 kelompok masing-masing berjumlah 6 ekor tikus, yaitu 1 kelompok kontrol negative tidak diberikan paparan asap rokok, 1 kelompok kontrol positif diberikan paparan asap rokok, 3 kelompok perlakuan diberikan paparan asap rokok dan pemberian ekstrak kulit buah naga merah dengan dosis 20mg, 40mg dan 80mg selama 14 hari. Parameter yang diukur adalah kadar MDA paru.Hasil: Rerata kadar MDA paru kelompok kontrol 1 adalah 0,146 ± 0,02 nmol/ml, rerata kelompok kontrol 2 adalah 0,166 ± 0,01 nmol/ml, rerata kelompok perlakuan 1 adalah 0,168 ± 0,03 nmol/ml, kelompok perlakuan 2 adalah 0,153 ± 0,02 nmol/ml, dan kelompok perlakuan 3 adalah 0,776 ± 0,09 nmol/ml. Analisis kemaknaan dengan uji One Way Anova menunjukan bahwa nilai F= 1,34 dan nilai p= 0,282, dimana nilai p>0,05Simpulan: Tidak ada perbedaan yang bermakna antara kelompok kontrol dengan kelompok perlakuan maupun antara kelompok perlakuan 1, perlakuan 2 dan perlakuan 3.
Perilaku siswa SDN 4 Antiga Kelod Karangasem terhadap infeksi soil transmitted helminth Ketut Teddy Bayu Pradinata; I Made Sudarmaja; Ni Luh Ariwati
Intisari Sains Medis Vol. 10 No. 3 (2019): (Available online: 1 December 2019)
Publisher : DiscoverSys Inc.

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (239.797 KB) | DOI: 10.15562/ism.v10i3.485

Abstract

Introduction: Soil Transmitted Helminths or (STH) is a group of parasitic worms (class of Nematodes) that can cause infection in humans through contact with the parasitic eggs or larvae themselves that develop in moist soils found in tropical countries and subtropics. Factors that can cause STH infection are due to lack of hygiene. This study aims to determine The correlation of Student’s behavior at SDN 4 Antiga Kelod, Karangasem and the Infection of Soil Transmitted HelminthMethod: This is a cross-sectional study. The source of the data came from primary data. Distribution of research variables are hand washing habits, nail cutting habits, open defecation habits, and behavior not using footwear. Data analysis is described in the form of tables and narratives.Result: From total 125 samples, 46 who had STH infection (33.09%), rare / never washed hands who had infections received a percentage of 100%, samples did not wear footwear infected with 74.4% with an OR of 14, an unclean nail sample infected at 86.5% with an OR of 34, a sample of the Chapter not in place that was infected was 52.6% with an OR of 2.Conclusion: The behavior of not using footwear properly has a 14 times greater risk than children who use footwear well to be infected with helminthiasis. unclean nail behavior has a risk 34 times greater than children who have clean nails to be infected with helminthiasis. Defecation behavior does not have the risk of being twice as large as in children who are defecating in the toilet to be infected with helminthiasis.Latar Belakang: Soil Transmitted Helminths atau (STH) adalah sekelompok cacing parasit (kelas Nematoda) yang dapat menyebabkan infeksi pada manusia melalui kontak dengan telur ataupun larva parasit itu sendiri yang berkembang di tanah yang lembab yang terdapat di negara yang beriklim tropis maupun subtropics. Faktor-faktor yang dapat menyebabkan terinfeksi STH yaitu oleh karena kurangnya perilaku menjaga kebersihan.  penelitian ini bertujuan untuk mengetahui perilaku Siswa SDN 4 Antiga Kelod Karangasem Terhadap Infeksi Soil Transmitted Helminth.Metode: Penelitian ini merupakan suatu penelitian cross-sectional. Sumber data berasal dari data primer. Distribusi variabel penelitian yaitu Kebiasaan mencuci tangan, Kebiasaan memotong kuku, kebiasaan buang air besar sembarangan, dan perilaku tidak menggunakan alas kaki. Analisis data di paparkan dalam bentuk tabel dan narasi.Hasil: dari 125 sampel, yang mengalami infeksi STH sebanyak 46 sampel (33,09%), sampel jarang/tidak pernah cuci tangan yang mengalami infeksi mendapatkan persentase sebesar 100%, sampel tidak memakai alas kaki yang terinfeksi sebesar 74,4% dengan OR sebesar 14, sampel kuku tidak bersih yang terinfeksi sebesar 86,5% denga OR sebesar 34, sampel Bab tidak pada jamban yang terinfeksi sebesar 52,6% dengan OR sebesar 2.Simpulan: Perilaku tidak menggunakan alas kaki dengan baik memiliki resiko 14 kali lebih besar sibanding anak yang menggunakan alas kaki dengan baik untuk terinfeksi penyakit kecacingan.  Perilaku kuku tidak bersih memiliki resiko 34 kali lebih besar dibanding anak yang memiliki kuku bersih untuk terinfeksi penyakit kecacingan. Perilaku BAB tidak pada tempatya memiliki resiko 2 kali lebih besar dibanding anak yang BAB pada jamban untuk terinfeksi penyakit kecacingan.
Pengaruh ekstrak krim Morinda citrifolia terhadap jumlah fibroblas pada penyembuhan luka tikus Wistar Vania Lannisa Haestidyatami; I Wayan Sugiritama; Ni Made Linawati
Intisari Sains Medis Vol. 10 No. 3 (2019): (Available online: 1 December 2019)
Publisher : DiscoverSys Inc.

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (228.86 KB) | DOI: 10.15562/ism.v10i3.487

Abstract

Introduction. Wound healing is a complex biological process involving four stages, i.e., hemostasis, inflammation, proliferation, and remodeling. In the proliferation phase, there is an increase in the number of fibroblas cells. Morinda citrifolia is a fruit that contains the antioxidant compound, Quercetin. These antioxidant properties are thought to be able to accelerate the process of wound healing through the process of modulating the oxidative process and improving skin microstructure. The relationship of Quercetin to fibroblas cells which plays an essential role in the proliferation phase is not yet fully known. This study was conducted to determine the effect of Morinda citrifolia extracts on the number of fibroblas cells during the process of wound healing in Wistar rats.Method. Experimental, post-test with control group study was conducted using 24 rats divided into four groups. In group I, rats were treated with incisions and given a Placebo cream, groups II, III and IV were given incisions and cream containing ethanol extract of Morinda citrifolia 5%, 10%, and 20% respectively. The number of fibroblass was calculated using the digital analysis method using Image Raster 3 Software. The number of fibroblas cells was calculated as the percentage of fibroblas cells seen in the field of view. Data analysis conducted with the One-Way ANOVA and Post-Hoc LSD test.Results. The control group had an average number of fibroblas cells 23.3% ± 1.9%. The mean fibroblas cells in the intervention group with extracts of 5%, 10%, 20% were 27.6% ± 6.7%, 38.3% ± 8.8% and 22.3% ± 2.7%, respectively. The ANOVA test results showed a significant difference in the number of fibroblass between treatment groups (p<0.001). Post-hoc LSD test shown that only the treatment group with 10% extract showed a difference in the average number of fibroblas cells compared to the other groups.Conclusion. The highest number of fibroblas cells was found in the treatment group with 10% extract.
Implementasi lintas diare dan penggunaan obat antidiare pada anak dengan diare Vidya Lakshmi Anbhuselvam; I Putu Gede Karyana; Ni Putu Siadi Purniti
Intisari Sains Medis Vol. 10 No. 3 (2019): (Available online: 1 December 2019)
Publisher : DiscoverSys Inc.

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (267.236 KB) | DOI: 10.15562/ism.v10i3.488

Abstract

Introduction: Diarrhea is still a major problem that causes illness and death for children in Indonesia. Inappropriate care, both at home and in health agencies, is a major cause of deaths of children with diarrhea.Method: The design of this study was descriptive with a cross sectional study design. The design of this study aims to be able to describe the implementation of cross diarrhea and the use of antidiarrheal drugs for pediatric patients with diarrhea at RSUP Sanglah Denpasar. The data used in the form of secondary data obtained from the medical records of Sanglah Hospital RSUP patients Denpasar January 2017-April 2017. The technique of determining the sample used is total sampling where all target populations that meet the criteria are included as samples.Result: The most widely used cross group of diarrheas was ORS (Oral Rehydration solution) (17.9%). The most commonly used antidiarrhea drug is adsorbent (11.6%).Conclusion: The most widely used cross-diarrhea group was ORS (Oral Rehydration solution) followed by the antibiotic group and so on the zinc group. There are minority cases that have given negative results on antibiotics. The most widely used group of antidiarrheal drugs was the adsorbent followed by the class of antimotility drugs and so on other classes of drugs such as probiotics and herbal medicinesLatar Belakang: Diare masih menjadi masalah utama yang menyebabkan sakit dan kematian bagi anak-anak di Indonesia. Perawatan yang tidak tepat, baik dirumah maupun di instansi kesehatan, merupakan penyebab utama kematian anak-anak dengan diare.Metode: Rancangan penelitian ini bersifat deskriptif dengan rancangan penelitian cross sectional. Rancangan penelitian ini bertujuan untuk dapat menggambarkan implementasi lintas diare dan penggunaan obat antidiare terhadap pasien anak dengan diare di RSUP Sanglah Denpasar. Data yang digunakan berupa data sekunder yang didapat dari rekam medis pasien Anak RSUP Sanglah Denpasar bulan Januari 2017-April 2017. Teknik penentuan sampel yang digunakan adalah total sampling dimana seluruh populasi target yang memenuhi kriteria dimasukan sebagai sampel.Hasil: Golongan lintas diare paling banyak digunakan adalah cairan rehidrasi yaitu oralit sebanyak 34 (17,9%). Penggunaan obat antidiare paling sering digunakan adalah adsorben sebanyak 22 (11,6%).Simpulan: Golongan lintas diare paling banyak digunakan adalah cairan rehidrasi yaitu oralit diikuti oleh golongan antibiotik dan seterusnya golongan zink. Terdapat kasus minoritas yang telah memberi hasil negatif pada pemberian antibiotik. Golongan penggunaan obat antidiare paling banyak digunakan adalah adsorben diikuti oleh golongan obat antimotilitas dan seterusnya golongan obat lain-lain seperti probiotik dan obat herbal

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