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INDONESIA
JURNAL FARMASIMED (JFM)
ISSN : -     EISSN : 26550814     DOI : -
Core Subject : Health,
Jurnal FARMASIMED (JFM) Volume I Nomor 1 Periode Mei - Oktober Tahun 2018. Jurnal ini memberikan ruang bagi akademisi, peneliti dan pengguna hasil penelitian dan pengabdian untuk mendiseminasikan, menginformasikan, mendiskusikan dan menggunakan hasil penelitian dan pengabdian sebagai upaya meningkatkan kualitas kebijakan di bidang farmasi yang berbasis ilmiah dan dapat dipertanggung jawabkan. Jurnal ini menyajikan hasil penelitian, pengabdian masyarakat serta artikel ilmiah di bidang farmasi.
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Articles 314 Documents
The Effect of Temulawak Extract (Curcuma xanthorrhiza Roxb.) on the Growth of Escherichia coli Shania Eugene Sutopo; Retno Budiarti; Chonifa Wahyurini
Jurnal FARMASIMED (JFM) Vol 8 No 2 (2026): Jurnal Farmasimed (JFM)
Publisher : Fakultas Farmasi Institut Kesehatan Medistra Lubuk Pakam

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35451/1nebdk14

Abstract

Background: Indonesia is a developing country that still faces many infectious diseases affecting its population, with one of the most common causes being the bacterium Escherichia coli. Antibiotics are used to treat bacterial infections; however, the increasing cases of antibiotic resistance in Indonesia have become a concerning public health issue. Temulawak (Curcuma xanthorrhiza Roxb.) is a traditional plant containing active compounds—especially flavonoids, xanthorrhizol, and curcumin—that possess antibacterial activity, making it a potential agent to inhibit the growth of Escherichia coli. Objective: To determine the effect of temulawak (Curcuma xanthorrhiza Roxb.) extract on the growth of Escherichia coli. Method: The inhibition of Escherichia coli growth was tested on Mueller Hinton media using the disc diffusion method. There were six treatment groups: negative control (sterile distilled water), positive control (Ciprofloxacin 500 mg), and extract concentrations of 25%, 50%, 75%, and 100%, each with four repetitions. Data were analyzed using the Kruskal-Wallis test followed by the Mann-Whitney U test. Result: The positive control showed an average inhibition zone diameter of 50.6 mm; 100% concentration: 10.6 mm; 75%: 10.2 mm; 50%: 8.90 mm (moderate inhibition); 25%: 7.52 mm; negative control: 6.00 mm. The Kruskal-Wallis test indicated a significant difference among the six groups with a significance value of 0.001 (p < 0.005). Conclusion: Temulawak (Curcuma xanthorrhiza Roxb.) extract at 100% concentration is the most effective treatment group in inhibiting the growth of Escherichia coli.
Antibacterial Test of Sand Sea Cucumber Extract (Holothuria scabra) Against the Growth of Staphylococcus aureus ATCC 25923 Carens Sintha Iralin De Ivanka; R.Varidianto Y.T; Suliman Purwoko
Jurnal FARMASIMED (JFM) Vol 8 No 2 (2026): Jurnal Farmasimed (JFM)
Publisher : Fakultas Farmasi Institut Kesehatan Medistra Lubuk Pakam

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35451/dgys3y87

Abstract

Background: Indonesia is a developing country with a high prevalence of infectious diseases with the most common cause being Staphylococcus aureus  bacteria. Treatment for S.aureus bacterial infection itself uses antibiotics. However, the high number of antibiotic resistance cases in Indonesia is a very important health problem. Indonesia itself is a country with a very wide sea so that a lot of marine wealth is very useful in health. One of them is sand sea cucumber which can help fight bacteria because it contains compounds such as saponins,and alkaloids, triterpenoids which are useful as antibacterials. The aims of the study is to determine the effectiveness of sand cucumber extract (Holothuria scabra) in various concentrations such as 25%, 50%, 75%, and 100% which is addressed through the inhibition zone produced against the growth of S.aureus bacteria. Objective: To determine the antibacterial activity of Sand cucumber extract (Holothuria scabra) by measuring the inhibition zone produced using the disc diffusion method. Method: There were 6 treatment groups in this study 4 of which were treatment groups with concentrations of 25%, 50%, 75%, and 100% and 2 control groups, namely the positive control group (amoxicillin) and the negative control group (sterile distilled water) where each group was repeated 4x. Then the data were analyzed using Kruskal Wallis test and continued with Mann-Whitney U test. Result: The average inhibition zone with a concentration of 25% produced an average inhibition zone of 7.12 mm; 50% concentration of 8.37 mm; 75% concentration had an inhibition of 9.41%, in the 100% treatment group produced an average inhibition zone of 11.68mm, negative control showed no inhibition, and positive control with an average inhibition zone of 16.93 mm.The Kruskal Wallis test showed that there was a significant mean difference between the 6 groups with a significant value of 0.001 (p<0.005). Conclusion: Sand cucumber extract (Holothuria scabra) can inhibit the growth of Staphylococcus aureus  ATCC 25923 bacteria so that it can be used as an alternative medicine or natural antibiotic.
The Effect of Pharmacist Intervention on Knowledge, Attitudes, and Hemoglobin Levels Among Adolescent Girls in Preventing Anemia Mirna Risna Lovinanda Lubis; Urip Harahap; Putri Chairani Eyanoer
Jurnal FARMASIMED (JFM) Vol 8 No 2 (2026): Jurnal Farmasimed (JFM)
Publisher : Fakultas Farmasi Institut Kesehatan Medistra Lubuk Pakam

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35451/w9gt8z66

Abstract

Background: Anemia is a common health problem among adolescent girls and may negatively affect physical health, concentration, and future reproductive health. Aim: This study aimed to analyze the effect of pharmacist intervention on hemoglobin levels, knowledge, and attitudes of adolescent girls in preventing anemia in Ujung Batu District, North Padang Lawas Regency. Methods:  A comparative experimental study with a one-group pretest-posttest design was conducted from October to November 2024. A total of 80 adolescent girls with anemia were selected using purposive sampling from junior high schools and Islamic boarding schools in Ujung Batu District. The intervention consisted of pharmacist-led education, counseling, and administration of iron supplementation tablets. Hemoglobin levels were measured using HemoCue Hb 301, while knowledge and attitudes were assessed using structured questionnaires. Data were analyzed using the Wilcoxon signed-rank test. Result: The results showed significant improvements after the intervention. Mean hemoglobin levels increased from 10.82 ± 0.49 g/dL to 13.35 ± 0.63 g/dL, knowledge scores increased from 44.75 ± 7.95 to 79.25 ± 7.50, and attitude scores increased from 67.23 ± 6.56 to 83.01 ± 5.12, with all variables showing statistical significance (p < 0.001). Conclusion: Pharmacist intervention was effective in improving hemoglobin levels, knowledge, and attitudes of adolescent girls regarding anemia prevention.
The Cost Reduction of Artificial Intelligence-Based Healthcare for Clinical Drug Use : A Literature Review Vitasari, Etika wahyu; Firman Pribadi
Jurnal FARMASIMED (JFM) Vol 8 No 2 (2026): Jurnal Farmasimed (JFM)
Publisher : Fakultas Farmasi Institut Kesehatan Medistra Lubuk Pakam

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35451/n6amkf09

Abstract

Artificial Intelligence (AI) evolves from experimental frameworks to essential clinical tools, it is crucial to assess its economic and clinical viability for drug use sustainability. This literature review examines the cost reduction and impact of AI in clinical drug management. In accordance with PRISMA 2020 guidelines, nine credible studies published between 2021 and 2026 were synthesized from databases including Pummeled, Scopus, and Google Scholar. The findings are organized into three key dimensions: medication safety and adherence, economic resource optimization, and human-AI synergy. The results indicate that medication adherence safety is demonstrated through the role of AI in detecting drug interactions (with ChatGPT-4.0), reducing the risk by 15.2% and improving therapy adherence, especially for TB treatment with AICure, and reducing the risk of hospitalization through clinical decision support. Economic resource optimization is reflected in a 17.3-17.4% reduction in treatment costs for 2,150 high-risk patients, along with the use of low-cost clinical inputs without compromising accuracy. Meanwhile, the synergy between humans and AI underscores the importance of transparent collaboration between healthcare professionals and technology to build trust, although gaps in understanding remain. Overall, AI integration contributes to safer, more efficient, and more collaborative healthcare. However, this review highlights knowledge gaps that may hinder the adoption of this technology. Findings indicate that the application of artificial intelligence significantly improves performance in the pharmaceutical industry while reducing costs, but its success depends on adapting the system to real-world constraints.