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Dina Keumala Sari
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Jl. Dr. T. Mansur No. 9 Padang Bulan, Kecamatan Medan Baru, Kota medan, Sumatera Utara, Indonesia
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Kota medan,
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Sumatera Medical Journal
Published by Universitas Sumatera Utara
ISSN : 26229234     EISSN : 26221357     DOI : 10.32734
Core Subject : Health, Science,
Immunology & microbiology Medicine & Pharmacology
Sumatera Medical Journal (SUMEJ) provides a forum for publishing the full research articles in the area of Medical Science related to topics from the following subject areas: -Cancer and Related Aspects -Biomoleculer in Basic Sciences -Biomoleculer in Clinical Sciences -Tissue Engineering including Stem Cell -Medical and Health Sciences
Arjuna Subject : Kedokteran - Kedokteran (Lain-Lain)
Articles 3 Documents
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Search results for , issue "Vol. 8 No. 2 (2025): Sumatera Medical Journal (SUMEJ)" : 3 Documents clear
Borassus flabellifer Effectively Reduces MDA Levels in High Oxidative Stress Population in Jakarta, Indonesia Digambiro, Reza Aditya; Marsiati, Himmi; Hadi, Restu Syamsul; Parwanto, Edy
Sumatera Medical Journal Vol. 8 No. 2 (2025): Sumatera Medical Journal (SUMEJ)
Publisher : Talenta Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32734/sumej.v8i2.18966

Abstract

Background: Malondialdehyde (MDA) is commonly used to assess oxidative stress levels. Objective: This study aimed to investigate the effect of Borassus flabellifer  fruit consumption on MDA levels in individuals with high oxidative stress, providing insights into the fruit’s potential as a natural antioxidant therapy. Methods: A prospective interventional study was conducted in Jakarta, recruiting fifty participants aged 30–60 years with baseline MDA levels >10 nmol/L. Participants consumed 150 grams of Borassus flabellifer fruit daily for 30 days. Blood samples were collected at baseline and post-intervention to assess MDA levels. Results: The average MDA level decreased significantly from 14.35 ± 2.43 nmol/L to 12.00 ± 1.74 nmol/L after 30 days of fruit consumption (p < 0.0001). The Cohen’s d value of 2.92 indicated a large effect size, demonstrating the intervention’s substantial impact. A strong positive correlation (r = 0.91, p < 0.0001) between baseline MDA levels and reduction was observed, suggesting that participants with higher baseline oxidative stress benefited more from the intervention. Conclusion: Borassus flabellifer fruit consumption effectively reduces MDA levels in individuals with high oxidative stress. The results support the inclusion of this fruit in recommendations for managing oxidative stress-related conditions.
Relationship Between Nutritional Status and Hemodialysis Therapy in Patients With Chronic Kidney Disease at Adam Malik Medan Hospital, Indonesia Nasution, Muhammad Siddik; Ramadani, Sumi; Ardiansyah, Edy; Paramita, Deryne Anggia
Sumatera Medical Journal Vol. 8 No. 2 (2025): Sumatera Medical Journal (SUMEJ)
Publisher : Talenta Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32734/sumej.v8i2.19070

Abstract

Background: One of the measures taken to control chronic kidney failure is through the hemodialysis procedure. Hemodialysis therapy can cause various side effects in patients, one of which is the risk of decreased nutritional status which can result in malnutrition. When the nutritional status of kidney failure patients worsens, the quality of life also decreases. Objective: This study aimed to determine the relationship between nutritional status and hemodialysis therapy at Haji Adam Malik General Hospital, Medan. Methods: This research was conducted from February to October 2024. This research is an analytical observational study using a cross sectional study design. The sample taken in this study was 80. Data was obtained from medical records at H. Adam Malik General Hospital, Medan. Results: The correlation test with the Chi-square test showed no relationship between Body Mass Index and several criteria, namely: Gender (p=0.645), age (p=0.410), creatinine (p=0.296), urea (p=0.296), albumin (p=0.315). Conclusion: There is no relationship between BMI and age, gender, albumin levels, creatinine levels and albumin levels in hemodialysis patients at H.Adam Malik General Hospital, Medan. The majority of patients undergoing hemodialysis at H.Adam Malik General Hospital Medan have a normal BMI (66%).
Levels of Squamous Cell Carcinoma Antigen and Interleukin-6 as Biomarkers in NSCLC Patients Arieta, Lydia; Soeroso, Noni Novisari; Tarigan, Setia Putra; Eyanoer, Putri Chairani
Sumatera Medical Journal Vol. 8 No. 2 (2025): Sumatera Medical Journal (SUMEJ)
Publisher : Talenta Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32734/sumej.v8i2.20027

Abstract

Background: Squamous Cell Carcinoma Antigen (SCC-Ag) and Interleukin-6 (IL‐6) has been widely used for monitoring Non-Small Cell Lung Cancer (NSCLC). Objective: This concentration also known to be higher in Non Small Cell Lung Cancer. Methods: This research used descriptive study among NSCLC patients. Blood sampling was used with serum. ELISA platform was used to rate SCC-Ag and IL-6 serum. Results: From 20 samples NSCLC, we found 20 males (100%), active smokers (80%). From histology type, Adenocarcinoma 12 cases (60%). The most of subjects were in stage IVA (70%). The Squamous Cell Carcinoma Antigen levels of NSCLC patients showed that as many as 20 samples (100%) were within normal limits and did not show an increased. Conclusion: Levels of IL-6 increased as many as 15 samples (75%), and IL-6 levels were still within the normal range sample (25%). Tumor marker are not meant to detect marker growth, but only as a marker that found in lung cancer,but IL-6 as the one of the pro-inflammation cytokines that shows an increased in patients NSCLC.

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