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Medica Hospitalia
Published by RSUP Dr. Kariadi Semarang
ISSN : 23014369     EISSN : 26857898     DOI : https://doi.org/10.36408/mhjcm
Core Subject : Health,
Dentistry Health Professions Medicine & Pharmacology Nursing Public Health
Medica Hospitalia: Journal of Clinical Medicine adalah jurnal ilmiah yang diterbitkan RSUP Dr. Kariadi dan menerima artikel ilmiah dalam bahasa Indonesia dan bahasa Inggris yang diharapkan dapat menjadi media untuk menyampaikan temuan dan inovasi ilmiah dibidang kedokteran atau kesehatan kepada para praktisi dan akedemisi di bidang kesehatan dan kedokteran.
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Articles 584 Documents
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PENGARUH AKTIVITAS FISIK JALAN KAKI TERHADAP KUALITAS TIDUR PADA IBU HAMIL TRIMESTER III
Medica Hospitalia : Journal of Clinical Medicine Vol. 13 No. 1 (2026): Med Hosp
Publisher : RSUP Dr. Kariadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36408/mhjcm.v13i1.1238

Abstract

BACKGROUND : Sleep disorders are common in pregnant women during the third trimester, with frequent urination being a prevalent issue due to weakened bladder muscles, leading to deteriorated sleep quality. Physical activity, such as walking, is recommended as an easy, effective, and economical way to improve sleep quality in pregnant women. AIMS :  To analyze the effect of walking on sleep quality in third-trimester pregnant women at Kebakkramat I Karanganyar Health Center, Central Java. METHOD : This study used a Quasi-Experimental design with a Pretest-Posttest Control Group approach. The sample consisted of 80 third-trimester pregnant women, selected using Multistage Sampling. The Pittsburgh Sleep Quality Index (PSQI) questionnaire was used to measure sleep quality. The intervention involved walking for 20 minutes over two weeks. RESULT :  The analysis used the Delta score mean test between the pre-tests and post-tests for each respondent to show a significant effect of walking on sleep quality. A negative delta value shows a decrease in the PSQI score, indicating improved sleep quality for the respondent, and vice versa. The intervention group had a lower delta score mean of -3.13 compared to the control group, indicating that walking effectively improves sleep quality. CONCLUSION : Walking has significant potential to improve sleep quality in third-trimester pregnant women. Pregnant women are encouraged to walk regularly and increase their knowledge about pregnancy.
Effectiveness Of Mar'ke Bilar Drink Formulation On Pro- Anti-Free Radicals In The Blood Of Women Of Childbearing Age Operators In Gas Stations Ginta Siahaan; Fauzi Romeli; R.R. Sri Arini Winarti Rinawati; Suriani br Ginting; Kenya Putri Kasi Sembiring Pandia; Ifta Maulida Tanjung
Medica Hospitalia : Journal of Clinical Medicine Vol. 12 No. 2 (2025): Med Hosp
Publisher : RSUP Dr. Kariadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36408/mhjcm.v12i2.1242

Abstract

BACKGROUND: Women of childbearing age who wortk at gas stations are vulnerable to pollution exposure due to fuel emissions. The workers are susceptible to heavy metal (Pb) poisoning in the fuel content. This can cause health problems such as reproductive disorders, impaired kidney function and can even cause anemia in women. AIMS: To determine the effectiveness of Mar'ke Bilar formulation on Pb, MDA, and SOD in blood. METHOD: The study was Quasi Experimental with a pre and post test group design that allows researchers to see the comparison of the control group with the experimental group. The sample in the study was Women of childbearing age who worked as operators at gas stations with a total of 60 people and were determined based on purposive sampling with inclusion criteria then divided into 4 treatment groups. Data analysis used the T-dependent test to see the differences in each group then continued with the One Way ANOVA and Post Hoc-Tukey tests. RESULT: The results of the study showed that the three of  Mar’ke Bilar formulations were effective in reducing Pb and MDA levels, as well as increasing SOD levels, which are endogenous antioxidant enzymes that are important in the body's defense against oxidative stress. While formula 1 proved to be the most effective in increasing SOD levels. CONCLUSION: Mar'ke Bilar affects blood Pb, MDA, and SOD levels and formulation 1 is the most effective in increasing SOD levels. It is necessary to consume colored foods such as Marke'Bilar which are very good for avoiding diseases caused by free radicals  by air and water pollution, especially those caused by heavy metals.
The Correlation Between Social Support And Incidence Of Depression In Coronary Heart Disease Patients
Medica Hospitalia : Journal of Clinical Medicine Vol. 13 No. 1 (2026): Med Hosp
Publisher : RSUP Dr. Kariadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36408/mhjcm.v13i1.1244

Abstract

BACKGROUND: Coronary heart disease can cause psychological impacts in the form of depression which, if not managed optimally, can worsen the patient's condition. One of the psychosocial factors that cause depression is low social support. Social support can strengthen individual coping with the acceptance of disease conditions in patients. AIMS: This study aims to determine the relationship between social support and depression in coronary heart disease patients at the Heart Installation of Dr. Kariadi Hospital Semarang. METHODS: This research is a descriptive quantitative correlation with a cross sectional approach. The research sample amounted to 39 respondents calculated by the Isaac and Michael formula with the sampling technique using accidental sampling. The research instruments used were Multidimensional Scale of Perceived Social Support (MSPSS) to assess social support and Beck Depression Inventory-II (BDI-II) to assess depression. RESULTS: The results of the Pearson Product Moment test showed a highly significant correlation between social support and depression (p = 0.000) with a value of r = -0.756 indicating a strong level of correlation with a negative correlation direction. CONCLUSION: The correlation between the two variables is strong and inversely proportional where the higher the social support received, the more depressive symptoms experienced will decrease. Family education is needed to maintain and increase social support to prevent and reduce depression in coronary heart disease patients.
The Risk of Bag-Carrying Related to Musculoskeletal Pain in Medical Students R. Ayu Aisyah Hanifah; Indri Seta Septadina; Ramadhan Ananditia Putra
Medica Hospitalia : Journal of Clinical Medicine Vol. 12 No. 2 (2025): Med Hosp
Publisher : RSUP Dr. Kariadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36408/mhjcm.v12i2.1247

Abstract

BACKGROUND: Musculoskeletal discomfort affects medical students' neck, shoulders, and back. Musculoskeletal pain may be linked to bag-carrying behaviors, which encompass the manner of carrying, duration of use, and weight of the bag. AIMS:  This study aims to determine the relationship between bag-carrying habits and musculoskeletal pain. METHOD: This is an observational analytic study with a cross-sectional approach. From 2022-2023, the research subjects were 70 Sriwijaya University medical students who met the inclusion and exclusion criteria. The sampling method employed a simple random sampling technique. We analyzed the obtained data using the Chi-square test in SPSS software. RESULT:  The majority of the subject was 20 years old and female. Most patients with musculoskeletal pain experience mild complaints in the lower neck (47.14%), right shoulder (41.43%), and back (41.43%). All of the p-values are> 0,05, including how to carry a bag, bag weight, and the duration of using a bag with neck, shoulder, and back pain among medical students of Sriwijaya University. CONCLUSION: There is no significant relationship between bag-carrying habits, which include how to carry a bag, bag weight, and the duration of using a bag, with neck, shoulder, and back pain among medical students of Sriwijaya University.
Kecemasan, Stres, dan Depresi pada Kekambuhan Gejala Gastritis diantara Narapidana Penyalahguna Narkoba di Bandung Angga Wilandika; Wulan Nurazizah; Santy Sanusi
Medica Hospitalia : Journal of Clinical Medicine Vol. 12 No. 3 (2025): Med Hosp
Publisher : RSUP Dr. Kariadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36408/mhjcm.v12i3.1248

Abstract

BACKGROUND: Drug abuse inmates in correctional institutions undergo rehabilitation programs and are supervised according to the determined sentence, thus losing their freedom. This condition causes psychosocial problems such as anxiety, stress, and depression, which may be associated with physical issues, including the recurrence of gastritis symptoms. AIMS:  To identify the correlation between anxiety, stress, and depression with recurrence of gastritis symptoms in drug abuse inmates at the correctional institution. METHOD: The study used a cross-sectional design and involved 34 inmates with a history of gastritis due to drug abuse. Purposive sampling was used to select the participants. The levels of anxiety, stress, and depression were measured using the Indonesian version of the Depression Anxiety Stress Scales (DASS-21). The Gastritis Recurrence Questionnaire evaluated the recurrence of gastritis symptoms in the inmates. The data was analyzed using descriptive statistics such as frequency distribution, and inferential analysis was conducted using the Kendal-tau test to identify correlations between the variables. RESULT: The study findings indicate a correlation between anxiety, stress, and depression and the recurrence of gastritis symptoms in inmates in correctional institutions (p-value < 0.05). Most inmates with a history of drug abuse experience psychosocial problems such as very high anxiety (29.4%) and severe stress (32.4%). At the same time, 73.5% do not experience depression.  CONCLUSION: Psychosocial issues like anxiety, stress, and depression have been found to contribute to the likelihood of recurrence of gastritis symptoms in inmates. The higher the levels of anxiety, stress, and depression, the greater the possibility of recurrence of gastritis symptoms. Correctional institution managers should be prepared to address these psychosocial issues to help inmates reduce the recurrence of gastritis symptoms.
Spatial and Temporal Analysis of Gallbladder Stone Cases at dr. Soekardjo Hospital, West Java: An Evidence-Based Study Mudatsir Mudatsir; Muhammad Raka El Ghifari; Fahmi Rahmat Amanulloh; Tryantini Sundi Putri; Andhy Romdani
Medica Hospitalia : Journal of Clinical Medicine Vol. 12 No. 2 (2025): Med Hosp
Publisher : RSUP Dr. Kariadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36408/mhjcm.v12i2.1249

Abstract

BACKGROUND: Gallbladder stone cases in East Priangan area have significantly increased due to diet, lifestyle, and stress levels of the community. However, studies on the seasonal variation of gallbladder stone cases remains limited, particularly in Indonesia. AIMS: This study aims to investigate the occurrence of gallbladder stone cases in East Priangan, West Java, Indonesia, based on the medical reports in 2022−2023. Furthermore, the dispersal of gallbladder stone cases is mapped as spatial and temporal distributions. METHOD: This study employed an observational, cross-sectional design. Data was collected from the medical records at dr. Soekardjo General Hospital of Tasikmalaya between January 2022 and December 2023. Data used in this study were available data of 2,032 visit records, comprising 1,311 visits in 2022 and 991 visits in 2023, for both inpatient and outpatient care. Two types of statistical tests were used in this study: the Chi-Square test and Moran's I value. RESULT:  The Global Moran’s I test revealed clusters in the spatial distribution of gallbladder stone for both 2022 (I = 0.434) and 2023 (I = 0.521). Additionally, monthly variations (p = 0.001), age (p = 0.023), and gender (p = 0.001) were found to be statistically significant factors influencing the risk of gallbladder stones. CONCLUSION: The spatial distribution of gallbladder stone was concentrated in the certain clusters. Moreover, there were significant correlations between monthly variations, age, and gender with gallbladder stones.
Comparison of Genotypic (t-NGS) and Phenotypic Results for Mycobacterium tuberculosis Identification and Drug Susceptibility Testing (DST) against Tuberculosis Paulina Rosa Evriarti; Yoeke Dewi Rasita; Harlindah Margawati; Sitti Fatimah Azzahra
Medica Hospitalia : Journal of Clinical Medicine Vol. 12 No. 3 (2025): Med Hosp
Publisher : RSUP Dr. Kariadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36408/mhjcm.v12i3.1256

Abstract

BACKGROUND: Accurate identification and drug susceptibility testing are crucial for tuberculosis eradication and treatment, but conventional methods require over four weeks to complete. Targeted Next Generation Sequencing (t-NGS) is a promising alternative that provides results in just four days, potentially replacing traditional methods. However, the concordance between genotypic and phenotypic methods has not been widely reported. AIMS: This study aims to see the concordance between  phenotypic and genotypic methods for identifying Mycobacterium tuberculosis and determining drug susceptibility. METHOD: Sputum samples were collected from Balai Besar Laboratorium Kesehatan Masyarakat (BBLKM) Makassar from June 2024 until July 2024. M. tuberculosis DNA was extracted using the Qiagen DNA mini kit, amplified with Deeplex® Myc-TB by Genoscreen, and prepared with Illumina DNA Prep. t-NGS was performed on the MiSeq Illumina platform, and sequencing results were analyzed with Deeplex® Myc-TB by Genoscreen. A comparison of genotypic and phenotypic results (Culture and Drug Sensitivity Test) was conducted using SPSS. RESULT: Discrepancies were noted between phenotypic and genotypic results for two samples (Samples 16 and 18), where phenotypic results indicated non-tuberculous mycobacteria (NTM) and genotypic results identified M. tuberculosis. These discrepancies were not statistically significant (p>0,05). Additionally, a minor discrepancy was observed in isoniazid results for one sample (Sample 2), but the statistical result is not significance (p>0.05). CONCLUSION: t-NGS is a promising alternative to conventional methods due to its shorter testing time and capability to identify novel mutations, with discrepancies compared to phenotypic results being statistically insignificant. However, its higher cost and the need for specialized expertise limit its accessibility to some laboratories.
Analysis of Risk Factors for The Severity of Hyaline Membrane Disease in Preterm Infants Based on Modality Chest X-Ray Aulia Kusuma Dewi; Farah Hendara Ningrum; Adhie Nur Radityo Suswihardhyono; Lydia Widyastuti Setjadiningrat Kuntjoro
Medica Hospitalia : Journal of Clinical Medicine Vol. 12 No. 1 (2025): Med Hosp
Publisher : RSUP Dr. Kariadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36408/mhjcm.v12i1.1283

Abstract

BACKGROUND : Hyaline membrane disease is one of the leading causes of morbidity and mortality in premature infants. Chest X-ray examination can significantly improve the diagnosis of hyaline membrane disease. AIMS :  This study aims to examine the relationship between risk factors and the severity of hyaline membrane disease using chest X-ray modalities. METHOD : An analytic observational study with a cross sectional and  retrospective approach was conducted. Consecutive sampling of 30 preterm infants’s medical records and thoracic X-ray at Dr. Kariadi Hospital Semarang was used. Data collection was carried out from April to July 2023. Statistical tests included the Contingency Coefficient Correlation Test and  Intraclass Correlation Coefficient (ICC). RESULT :  Findings indicate that HMD severity is associated with lower birth weights (p = 0.020; r = 0.392); gestational ages (p = 0.011; r = 0.420) and maternal hypertension (p = 0.013; r = 0.414). Preeclampsia, delivery method, and gender not significantly related to the HMD severity (p>0.05). CONCLUSION : Infant birth weight, gestational age, and maternal hypertension are significantly associated with the severity of hyalin membrane disease.
Zero Fluoroscopy Transcatheter Device Closure in Subaortic Ventricular Septal Defect Marco Wirawan Hadi; Tahari Bargas Prakoso; Rille Puspitoadhi Harjoko; Sefri Noventi Sofia
Medica Hospitalia : Journal of Clinical Medicine Vol. 12 No. 2 (2025): Med Hosp
Publisher : RSUP Dr. Kariadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36408/mhjcm.v12i2.1289

Abstract

Background: For the last decade, transcatheter closure of ventricular septal defect (VSD) has been the treatment of choice, using fluoroscopy as a guide. However, the risk of radiation and/or contrast agent exposure has been an issue, especially in young patients. We would like to highlight the first case of zero fluoroscopy transcatheter VSD closure in Central Java. Case Illustration: A 27-year-old female was referred to outpatient department due to worsening shortness of breath in the last 3 months before admission. She had a history of recurrent respiratory tract infections, feeding difficulty, and failure to thrive. Her vital signs were stable, 99% oxygen saturation, and grade 3/6  pansystolic murmur in the lower left sternal border. Transoesophageal echocardiography showed 3 mm subaortic VSD, left to right shunt. Transcatheter VSD closure was successfully done using Konar-MF™ VSD Occluder No. 8/6 mm retrograde approach without fluoroscopy. Conclusion: The first zero fluoroscopy transcatheter device closure in Central Java has been successfully done in a 27-year-old female with subaortic VSD. Zero fluoroscopy transcatheter VSD closure is a feasible, safe, and effective procedure.
The Effect of Vitamin D Supplementation on Sputum Conversion, Erythrocyte Sedimentation Rate and Neutrophil-Lymphocyte Ratio in Pulmonary Tuberculosis Patients – A Randomized Controlled Trial Muchamad Regi Sonjaya; Mohamad Isa; Alfi Yasmina; Isa Ansori; Ira Nurrasyidah; Erna Kusumawardhani
Medica Hospitalia : Journal of Clinical Medicine Vol. 13 No. 1 (2026): Med Hosp
Publisher : RSUP Dr. Kariadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36408/mhjcm.v13i1.1290

Abstract

BACKGROUND : The health issue of pulmonary tuberculosis (TB) remains a concern in Indonesia. Vitamin D supplementation is one way to manage tuberculosis, which is a crucial case control metric. It is anticipated that vitamin D's anti-inflammatory properties will lower erythrocyte sedimentation rate (ESR) and inflammatory indicators, hence speeding up sputum conversion. AIMS :  To analyze the effect of vitamin D supplementation on sputum conversion, ESR and neutrophil-lymphocyte ratio (NLR) among pulmonary tuberculosis patients METHOD : Patients with pulmonary tuberculosis who were treated as outpatients at Ulin Banjarmasin Hospital and Pekauman Health Centre between May-July 2024 and who satisfied the study's inclusion requirements were included in the randomised controlled trial. Subjects were randomly divided into 2 groups (19 subjects in the treatment group and 19 subjects in the control group) using random selection with sealed envelopes. The treatment group received antituberculosis drugs (ATD) and vitamin D supplementation at a dose of 10,000 IU/day for eight weeks after the initiation of TB therapy, while the control group received ATD and a placebo. ESR and NLR examinations were performed prior to treatment, in weeks 4 and 8, whereas sputum evaluations were conducted at weeks 2, 4, 6, and 8. Statistical Product and Service Solutions (SPSS) was used for data analysis. P-value <0,05 was significant statistically. RESULT :  The study subjects were 38 pulmonary TB patients, most of whom were women (65.0%) with an average age of 50.42 ± 18.61 years. Overall, during the 8 weeks of intervention, there was a significant effect of vitamin D supplementation on sputum conversion (OR = 1.61, 95%CI = 0.030-0.931, p = 0.037). There was no significant effect of vitamin D supplementation on NLR (regression coefficient = 0.549, 95%CI = -1.769-2.858, p = 0.641) and ESR (regression coefficient = -5.529, 95%CI = -20.658-9.599, p = 0.474). CONCLUSION : Vitamin D supplementation significantly affects sputum conversion. In the 8th week, almost all subjects who initially had positive BTA became negative. But does not significantly affect ESR and NLR.

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