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Majalah Biomorfologi (Biomorphology Journal)
Published by Universitas Airlangga
ISSN : 02158833     EISSN : 27160920     DOI : 10.20473/mbiom.v30i1.2020.1-7
Core Subject : Health, Science,
Biochemistry, Genetics & Molecular Biology Health Professions Medicine & Pharmacology Neuroscience Public Health
Majalah Biomorfologi publishes articles in the form of original research report, excel-literature review, communication and special case report. The scope of this journal includes Medicine and Health sciences, focusing in basic and applied Anatomy and Histology (i.e., neuroscience, medical and health education, anthropology, clinical genetics, embryology, medical education, clinical anatomy, histotechnics, and photomicroscopy) although other correlated topics are also welcomed.
Arjuna Subject : Kedokteran - Anatomi
Articles 116 Documents
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HEMATOLOGY PROFILES AND DISEASE SEVERITY OF PEDIATRIC DENGUE VIRUS INFECTION AT A TERTIARY HOSPITAL IN SURABAYA, INDONESIA Annisa Fira Salsabila; Juniastuti; Dominicus Husada; Dwiyanti Puspitasari
Majalah Biomorfologi Vol. 34 No. 1 (2024): MAJALAH BIOMORFOLOGI
Publisher : Universitas Airlangga, Surabaya, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/mbiom.v34i1.2024.1-9

Abstract

Highlights Dengue virus infections exhibit a spectrum of clinical manifestations, ranging from asymptomatic cases to severe disease, with the potential for fatalities if not managed effectively. Hematology factors significantly contribute to the severity of dengue virus infection.   Abstract Background: The escalating incidence of dengue cases in Surabaya, Indonesia, underscores the imperative to comprehend the hematology profiles and disease severity in pediatric patients affected by dengue virus infections (DVI). As the prevalence of DVI continues to surge, understanding the nuanced clinical manifestations becomes paramount for effective management and mitigation of the disease burden. Objective: This study aimed to characterize the hematology profiles and the disease severity of dengue virus infections (DVI) among pediatric patients hospitalized at Dr. Soetomo General Academic Hospital, Surabaya, Indonesia throughout 2019. Material and Method: A retrospective descriptive cross-sectional study was conducted using secondary data from medical records. Pediatric patients aged six months to 18 years were enrolled. A total sampling method comprised 67 patients meeting the inclusion criteria. Result: Severe thrombocytopenia was most commonly observed in dengue hemorrhagic fever (DHF) III cases (36.4%), while leukopenia was predominant in DF cases (42.2%). High hematocrit levels were more prevalent in DHF III cases (27.3%), and high hemoglobin levels were most frequently identified in DHF II and DHF III cases (33% in each case). Significant differences in DVI severity were observed in platelets and hemoglobin levels (p=0.0002 and p=0.0066, respectively) but not in leukocyte and hematocrit levels. Conclusion: Mild thrombocytopenia was prevalent in Dengue Fever (DF), while severe thrombocytopenia was most prevalent in Dengue Hemorrhagic Fever (DHF) grade III. Leukopenia was prominent in DF patients, and platelets and hemoglobin levels varied across severity of DVI. These findings provide insights for improved clinical management and diagnostic criteria refinement.
ARE THE GINGIVAL DISPLAY AND THE SMILE ARC IN MALES AND FEMALES DIFFERENT? Wita Anggraini; Indrani Sulistyowati; Annisaa Putri Ariyani; Stephany Alexandra
Majalah Biomorfologi Vol. 34 No. 1 (2024): MAJALAH BIOMORFOLOGI
Publisher : Universitas Airlangga, Surabaya, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/mbiom.v34i1.2024.26-35

Abstract

Highlights Gingival display and smile arc enhance the aesthetic value of a person's smile and may be influenced through dental treatment. The individual profile photographs taken during social smiles can be used to evaluate dental treatment plans.   Abstract Background: An aesthetic smile is part of a person's attraction and affects their level of psychosocial well-being. Gingival display and smile arc belong to smile components that enhance the aesthetic value of a person's smile. Objective: To determine the differences in gingival display and smile arc in social smiles between males and females. Material and method: This analytical observational study was conducted with a cross-sectional design. A total of 110 photographs (55 males and 55 females) of study subjects who fulfilled the inclusion criteria were taken directly by Canon EOS-600D while performing social smile poses. The CorelDraw Graphic Suite 2022 measured gingival appearance and smile curves. The Chi-square test was performed to analyze the differences in gingival display and smile arc between males and females. Result: Based on gingival display, social smiles between genders were categorized into moderate (56.4% males and 58.2% females), low (30.9% males and 20% females), high (9.1% males and 18.2% females), and very high (3.6% males and females) smile lines. Social smiles based on smile arc were categorized into consonant (85.5% males and 96.4% females), straight (10.9% males and 3.6% females), and inverted (3.6% men and 0% women) smiles. No statistical differences were found in gingival display (p=0.397) or smile arc (p=0.113). Conclusion: There were no significant differences in gingival display or smile arc between males and females. Females, on the other hand, had an increased gingival show while smiling and no inverted smile arc.
AGE, SEX, AND TYPES OF OCCUPATION WITH HISTOPATHOLOGICAL TYPES IN PATIENTS WITH OCULAR SURFACE SQUAMOUS NEOPLASIA (OSSN) IN A TERTIARY HOSPITAL IN SURABAYA, INDONESIA Stella Agatha Widjaja; Delfitri Lutfi; Linda Dewanti; Alphania Rahniayu; Fitria Kusumastuti
Majalah Biomorfologi Vol. 34 No. 2 (2024): MAJALAH BIOMORFOLOGI
Publisher : Universitas Airlangga, Surabaya, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/mbiom.v34i2.2024.74-82

Abstract

Highlights The histopathological types of OSSN were significantly associated with age and occupation. The study's findings enhance the understanding of OSSN in Indonesia and emphasize the importance of UV exposure, occupation, and age in its development.   Abstract Background:  Ocular Surface Squamous Neoplasia (OSSN) is a spectrum of tumors affecting the conjunctiva and cornea, in which a more invasive type of OSSN has a higher recurrence rate. As a tropical country, Indonesia is constantly exposed to intense ultraviolet (UV) radiation, the main risk factor for OSSN. Despite this, there are very few studies regarding OSSN in Indonesia. Objective:  This study aimed to analyze the association between sociodemographic characteristics such as age, sex, and types of occupation (outdoor and indoor) and histopathological types of OSSN to fill the gap in research and contribute to early diagnostic strategies. Material and Method: Sociodemographic and histopathological data were extracted from the medical records of patients who were histopathologically diagnosed with OSSN at Dr. Soetomo General Hospital from 2017 to 2021. Data from 88 samples that met the inclusion and exclusion criteria were classified and analyzed with descriptive statistics and a two-sided Fisher's exact test using SPSS version 27.0 (IBM Corp., Armonk, N.Y., USA). Result: The exact test results of the two-sided fisher revealed a statistically significant relationship between age (p = 0.0004) and occupation type (p = 0.049) with histopathological types of OSSN. However, no significant association was found between sex and histopathological types of OSSN (p = 0.130). Conclusion: Age and occupation were found to have a significant association with the histopathological types of OSSN, reinforcing the need for further exploration of its strength and nature to be considered by future researchers.
FEATURES OF THE CLINICAL MANIFESTATIONS OF AUTOIMMUNE OPTIC NEUROPATHY IN MULTIPLE SCLEROSIS ON CORTICOSTEROID THERAPY Dalia Sharliz Raihana; Lukisiari Agustini; Deasy Fetarayani
Majalah Biomorfologi Vol. 34 No. 2 (2024): MAJALAH BIOMORFOLOGI
Publisher : Universitas Airlangga, Surabaya, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/mbiom.v34i2.2024.123-133

Abstract

Highlights Intravenous corticosteroid treatment followed by oral clinical treatment can reduce the incidence of post-treatment optic neuritis recurrenc Visual acquisition increases at one-month post-treatment.   Abstract Background: The clinical picture of autoimmune optic neuropathy, known as neuritis, is strongly influenced by the unique structure of the human anterior visual pathway. The central nervous system autoimmune is related to multiple sclerosis (MS). Optic neuropathy is an injury that frequently results in acute inflammatory damage. Objective: This study aimed to determine the clinical manifestations of autoimmune optic neuropathy in multiple sclerosis and identify diseases with appropriate corticosteroid therapy using systematic review methods. Material and Method: This study used a systematic review method to analyze topic-related kinds of literature on  Scopus, PubMed, and Google Scholar databases. The literature screening process was carried out based on the PRISMA 2020 guidelines. Result: Regarding the post-treatment recurrence rate of optic neuritis, the use of intravenous corticosteroids alone and intravenous corticosteroid followed by oral administration may clinically reduce the incidence of recurrence in the patients compared those receiving placebo and oral administration. This suggests that intravenous corticosteroid followed by oral corticosteroid treatment is effective in helping to reduce the incidence of recurring optic neuritis. Conclusion: Intravenous corticosteroid treatment followed by oral administration may clinically reduce the incidence of post-treatment recurrence of optic neuritis in multiple sclerosis (MS) patients.
POTENTIAL OF RED OKRA (Abelmoschus esculentus (L.) Moench) ETHANOL EXTRACT TO PROTECT AGAINST 7, 12-DIMETHYLBENZ[A]ANTHRACENE-INDUCED DAMAGE IN RAT'S (Rattus norvegicus) Liver Lukiteswari Dyah Tri Hapsari; Kusuma Eko Purwantari; Indri Safitri Mukono; Sri Puji Astuti Wahyuningsih; Nadyatul Ilma Indah Savira
Majalah Biomorfologi Vol. 34 No. 1 (2024): MAJALAH BIOMORFOLOGI
Publisher : Universitas Airlangga, Surabaya, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/mbiom.v34i1.2024.10-18

Abstract

Highlights: Red okra pods have a potential antioxidant to protect against DMBA-induced damage in a rat's liver. The liver protection with ROE decreased reversible and irreversible cellular damage from 51.8% to 35%, 27.3%, and 18.9%.   Abstract Background: Okra (Abelmonchus esculentus (L.) Moench) is a plant that has potential for humans and health because it contains high antioxidants such as polyphenols. Objective: This study aimed to analyze the red okra pods' ethanol extract (ROE) antioxidant potential to protect rat (Rattus norvegicus L.) liver against damage by induction of 7, 12-dimethyl-benz[a]anthracene (DMBA). Material and Method: The material used was various doses of red okra pods with ethanol as solvent. Twenty-five female rats (4 weeks, body weight 140”150 g) were divided into five groups: negative control (receiving a single dose of 0.5 mL corn oil as DMBA solvent), positive control (receiving a single dose induction of DMBA 80 mg/kg BW dissolved in 0.5 mL corn oil), and treatment groups 1, 2, 3 (receiving a single dose of DMBA 80 mg/kg BW dissolved in 0.5 mL corn oil and ROE of 50, 100, and 200 mg/kg BW, respectively, daily for 35 days). On day 36, the livers were removed and prepared for histopathological observation using hematoxylin-eosin staining. The method of histopathological score was determined using an ordinal score. Result: The data were analyzed statistically (p>0.05). All ROE doses showed a significant decrease in the histopathological score of rats' liver damage caused by DMBA-induced. The liver protection with ROE reduced the percentages of reversible and irreversible cellular damage from 51.8% to 35%, 27.3%, and 18.9%, respectively. Conclusion: The red okra pod ethanol extract can protect against DMBA-induced liver damage in rats.
Front Matter Vol. 30 No. 1 January 2020 Majalah Biomorfologi
Majalah Biomorfologi Vol. 30 No. 1 (2020): MAJALAH BIOMORFOLOGI
Publisher : Universitas Airlangga, Surabaya, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/mbiom.v30i1.2020.%p

Abstract

Back Matter Vol. 30 No. 1 January 2020 Majalah Biomorfologi
Majalah Biomorfologi Vol. 30 No. 1 (2020): MAJALAH BIOMORFOLOGI
Publisher : Universitas Airlangga, Surabaya, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/mbiom.v30i1.2020.%p

Abstract

Front Matter Vol. 30 No. 2 July 2020 Majalah Biomorfologi
Majalah Biomorfologi Vol. 30 No. 2 (2020): MAJALAH BIOMORFOLOGI
Publisher : Universitas Airlangga, Surabaya, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/mbiom.v30i2.2020.%p

Abstract

Back Matter Vol. 30 No. 2 July 2020 Majalah Biomorfologi
Majalah Biomorfologi Vol. 30 No. 2 (2020): MAJALAH BIOMORFOLOGI
Publisher : Universitas Airlangga, Surabaya, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/mbiom.v30i2.2020.%p

Abstract

Front Matter Vol. 31 No. 1 January 2021 Majalah Biomorfologi
Majalah Biomorfologi Vol. 31 No. 1 (2021): MAJALAH BIOMORFOLOGI
Publisher : Universitas Airlangga, Surabaya, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/mbiom.v31i1.2021.%p

Abstract

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