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SCRIPTA SCORE Scientific Medical Journal
Published by Universitas Sumatera Utara
ISSN : 20888686     EISSN : 26860864     DOI : https://doi.org/10.32734/scripta.v1i2
Core Subject : Health,
Medicine & Pharmacology
SCRIPTA SCORE Scientific Medical Journal is a journal aimed to provide a forum for publishing scientific articles in the field of medical or health science. The main focus of SCRIPTA SCORE Scientific Medical Journal is tropical medicine and oncology medicine also the rest of medical fields as the additional focus. To achieve its aim, SCRIPTA SCORE Scientific Medical Journal publishes research articles, review articles, and case reports especially manuscript with a regional or national data to raise the interest of the reader in tropical medicine or oncology medicine as the main focus and the rest of medical fields as the addition focus.
Arjuna Subject : Kedokteran - Kedokteran (Lain-Lain)
Articles 148 Documents
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The Relationship of Apolipoprotein B and Major Adverse Cardiovascular Events (MACE) in Patients with Coronary Heart Disease as a Prognostic Factor: A Literature Review Radyaputri, Andrea
SCRIPTA SCORE Scientific Medical Journal Vol. 5 No. 2 (2024): SCRIPTA SCORE Scientific Medical Journal
Publisher : Talenta Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32734/scripta.v5i2.15234

Abstract

Background: All lipoproteins containing Apo-B contribute to the risk of major adverse cardiovascular events (MACE). Although low-density lipoprotein cholesterol (LDL-C) is the most common marker to assess the risk associated with dyslipidemia, Apo-B levels reflect excess atherosclerotic risk and proatherogenic shifts in lipoprotein, predict the risk of incidental atherosclerotic cardiovascular disease, MACE following ACS, including mortality compared to LDL-C. Objectives: This review is held to examine the clear association between Apo-B with MACE in patients with coronary heart disease. Methods: Studies examining the relationship between Apo-B and MACE in coronary heart disease published in 2018-2023 are searched comprehensively using advanced search on PubMed, Google Scholar, and Cochrane. The relevant studies in Indonesian or English are included and qualitatively reviewed. Result and Discussion: There are 17,392 studies identified, four of which meet the inclusion criteria and have low risks of bias in most domains. Study indicates Apo-B levels are significantly associated with the long-term risk of MACEs, especially in patients with comorbidities. After primary PCI, high Apo-B levels predict a greater and significant incidence of MACE compared to LDL-C and non-HDL-C. Apo-B reduction also triggers a significant decrease in MACE, unlike non-HDL-C control. Hence, lipid therapy after ACS should focus on Apo-B. Low Apo-B correlates with malnutrition, old age, comorbidities thus indicating a worse prognosis for ACS. Therefore, identification of comorbidities should be considered. Conclusion: This review provides strong evidence that Apo-B level has better prognostic information of MACE following coronary heart disease, especially in patients with comorbidities, compared to other lipid profiles. Therefore, controlled Apo-B is preferred as a therapy target. Keyword: Apo-B, coronary, heart, MACE, prognosis   Latar Belakang: Semua lipoprotein yang mengandung Apo-B berkontribusi terhadap risiko kejadian kardiovaskular utama yang merugikan (MACE). Meskipun kolesterol lipoprotein densitas rendah (LDL-C) adalah penanda yang paling umum digunakan untuk menilai risiko yang terkait dengan dislipidemia, kadar Apo-B mencerminkan risiko aterosklerotik berlebih dan pergeseran proaterogenik dalam lipoprotein, memprediksi risiko penyakit kardiovaskular aterosklerotik insidental, MACE setelah sindrom koroner akut (ACS), termasuk kematian dibandingkan dengan LDL-C. Tujuan: Tinjauan ini bertujuan menelaah hubungan yang jelas antara Apo-B dengan MACE pada pasien dengan penyakit jantung koroner. Metode: Studi yang meneliti hubungan Apo-B dengan MACE pada pasien penyakit jantung koroner dan dipublikasikan pada 2018-2023 dicari secara komprehensif menggunakan metode pencarian lanjut di Pubmed, Google Scholar, dan Cochrane. Studi yang relevan dalam bahasa Indonesia atau Inggris diinklusi dan ditelaah secara kualitatif. Pembahasan: Dari 17.392 studi yang teridentifikasi, sebanyak 4 studi sesuai dengan kriteria inklusi serta memiliki risiko bias rendah pada mayoritas domain. Studi menunjukkan bahwa kadar Apo-B secara signifikan berhubungan dengan risiko MACE jangka panjang, terutama pada pasien dengan komorbiditas. Setelah PCI primer, kadar Apo-B tinggi memprediksi insiden MACE yang lebih besar dan signifikan dibandingkan LDL-C dan non-HDL-C. Penurunan Apo-B memicu penurunan MACE signifikan, berbeda dengan non-HDL-C. Oleh karena itu, terapi lipid setelah ACS sebaiknya berfokus pada Apo-B. Kadar Apo-B rendah berkorelasi dengan malnutrisi, usia tua, komorbiditas sehingga menunjukkan prognosis yang lebih buruk untuk ACS. Oleh karena itu, identifikasi komorbiditas dipertimbangkan. Kesimpulan: Telaah ini memberikan bukti kuat bahwa kadar Apo-B menyediakan informasi prognostik MACE lebih baik setelah penyakit jantung koroner, terutama pada pasien dengan komorbiditas, dibandingkan dengan profil lipid lainnya. Oleh karena itu, pengendalian Apo-B lebih dipilih sebagai target terapi. Kata Kunci: Apo-B, koroner, jantung, MACE, prognosis
Dermatitis Herpetiformis: An Update on Diagnosis And Treatment Hazlianda, Cut Putri; Putri, Desy Sahara
SCRIPTA SCORE Scientific Medical Journal Vol. 5 No. 2 (2024): SCRIPTA SCORE Scientific Medical Journal
Publisher : Talenta Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32734/scripta.v5i2.15636

Abstract

Introduction: Dermatitis herpetiformis is a relapsing skin disease caused by gluten sensitivity, also known as an extraintestinal manifestation of celiac disease. Methods: This article was made by reviewing 14 articles related to dermatitis herpetiformis which obtained from Pubmed, Science Direct, and Google Scholar. Discussion: Dermatitis herpetiformis is characterized by skin lesions vesicles or exoriated papules intensely itchy or excoriated papules on extensor surfaces, scalp, nuchal area, and buttocks. Dermatitis herpetiformis is primarily diagnosed through direct immunofluorescence of granular IgA deposits. However, modern and recent approaches currently use anti-TG3 antibody levels as the main serological diagnostic marker. Recent studies now confirm strict, long-term gluten free diet as the primary treatment modality. The diet is supplemented with sulfonamides as first line drugs treatment, especially dapsone. Proper diagnosis and management are important to improve the quality of life of the patients. Conclusion: Dermatitis herpetiformis is a skin disease related to hypersensitivity which requires comprehensive approach and treatment. Keyword: Celiac Disease, Dapsone, Dermatitis Herpetiformis, Direct Immunofluorescence, Gluten Free Diet Pendahuluan: Dermatitis herpetiformis, juga dikenal sebagai manifestasi ekstraintestinal penyakit celiac. Metode: Artikel ini disusun dengan meninjau 14 artikel berkaitan dengan dermatitis herpetiformis yang didapatkan pada Pubmed, Science Direct, dan Google Scholar. Pembahasan: Dermatitif herpetiformis adalah penyakit kulit yang ditandai dengan vesikel yang gatal atau papula yang terkelupas. Dermatitis herpetiformis didiagnosis terutama melalui imunofluoresensi langsung deposit IgA granular. Namun, pendekatan modern saat ini menggunakan antibodi anti-TG3 sebagai penanda diagnostik serologis utama. Studi terbaru sekarang mengkonfirmasi diet bebas gluten jangka panjang yang ketat sebagai modalitas pengobatan utama. Diet dilengkapi dengan sulfonamida sebagai pengobatan lini pertama, terutama dapson. Diagnosis dan penatalaksanaan yang tepat penting untuk meningkatkan kualitas hidup pasien. Kesimpulan: Dermatitis herpetiformis adalah penyakit kulit yang berkaitan dengan hipersensitivitas dan membutuhkan pendekatan dan tatalaksana yang komprehensif. Kata Kunci: Dapson, Dermatitis Herpetiformis, Diet Bebas Gluten, Imunofluoresensi Langsung, Penyakit Seliak
Front & Back Matter
SCRIPTA SCORE Scientific Medical Journal Vol. 5 No. 2 (2024): SCRIPTA SCORE Scientific Medical Journal
Publisher : Talenta Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32734/scripta.v5i2.15811

Abstract

Diagnosis Tiroiditis Hashimoto pada Seorang Wanita dengan Hipotiroidisme Subklinis dan Trombositopenia: Laporan Kasus Cahyani, Devi Aulia; Masita, Annisa Nur
SCRIPTA SCORE Scientific Medical Journal Vol. 6 No. 1 (2024): SCRIPTA SCORE Scientific Medical Journal
Publisher : Talenta Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32734/scripta.v6i1.15187

Abstract

Background: Hashimoto’s Thyroiditis (TH) is a variety of autoimmune thyroid disorders. It discovered incidentally, asymptomatic and generally normal thyroid profile, therefore it might adventurous to be diagnosed. Objectives: To describe establishing TH diagnosis in a woman with subclinical hypothyroidism and thrombocytopenia. Case Illustration: A woman, 46 years old, referred fatigue, joints pain and neck lump for about ± a year, physical examination was found diffuse goiter, USG examination was found TIRADS 2, laboratory examination was found thrombocytopenia, euthyroid, anti-TPO 203,8 IU/mL. Discussion: USG was concluded solid lesion visualized typical thyroiditis without FNAB required and anti-TPO results was appropriate with TH predictor>121,0 IU/ml. Numerous of studies showed TH which occurred with secondary immune thrombocytopenia. Conclusion: Subclinical hypothyroidism which presented diffuse goiter and higher normal TSH required USG and anti-TPO examination for established its diagnosis. Persistent thrombocytopenia might be suspected as autoimmune thyroid disorder especially whether presented goiter. Latar Belakang: Tiroiditis Hashimoto (TH) merupakan penyakit autoimun kelenjar tiroid. Penyakit ini ditemukan secara insidental, asimptomatik dan umumnya profil tiroid dalam batas normal sehingga mendiagnosisnya menjadi tantangan tersendiri. Tujuan: Menjelaskan penegakan diagnosis TH pada wanita dengan hipotiroidisme subklinis dan trombositopenia. Ilustrasi Kasus: Seorang wanita 46 tahun mengeluhkan cepat lelah, linu, benjolan leher selama ±1 tahun, pemeriksaan fisik didapatkan goiter difus, pemeriksaan USG didapatkan TIRADS 2, pemeriksaan laboratorium didapatkan trombositopenia, eutiroid, anti-TPO 203,8 IU/mL. Pembahasan: USG disimpulkan lesi solid mengesankan tiroiditis tanpa perlu FNAB dan anti-TPO sesuai dengan prediktor TH >121,0 IU/ml. Banyak studi menyebutkan TH yang disertai immune thrombocytopenia sekunder. Kesimpulan: Hipotiroidisme subklinis berupa goiter difus dan TSH sedikit meningkat perlu dilakukan USG dan anti-TPO untuk penegakan diagnosisnya. Trombositopenia persisten dapat dicurigai penyakit autoimun tiroid terutama bila terdapat goiter.
Hubungan Tingkat Pengetahuan Terhadap SIkap dan Perilaku Masyarakat Tentang Penggolongan Obat Tradisional di Indonesia di Kecamatan Medan Tembung Nainggolan, Zefanya Grace Winneke; Rina Amelia; Dalimunthe, Dina Arwina; Nasution, Afrida Aryani
SCRIPTA SCORE Scientific Medical Journal Vol. 6 No. 1 (2024): SCRIPTA SCORE Scientific Medical Journal
Publisher : Talenta Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32734/scripta.v6i1.15388

Abstract

Pendahuluan. Keanekaragaman hayati Indonesia sangat tinggi, terdapat sekitar 30.000 spesies tumbuhan di Indonesia yang memiliki khasiat obat atau bisa dimanfaatkan sebagai obat tradisional. Pengobatan tradisional telah lama menjadi bagian esensial dari sistem pengobatan di Indonesia. BPOM pada tahun 2004 menggolongkan obat tradisional berdasarkan uji klinis menjadi jamu, obat herbal terstandar, dan fitofarmaka. Tujuan. Menganalisis hubungan tingkat pengetahuan terhadap sikap dan perilaku masyarakat tentang penggolongan obat tradisional di Indonesia di Kecamatan Medan Tembung Metode penelitian. Penelitian ini merupakan studi observasional analitik dengan pendekatan cross-sectional. Data penelitian dikumpulkan dengan menggunakan instrumen kuesioner yang berisikan pertanyaan untuk mengukur tingkat pengetahuan, sikap, dan perilaku. Sampel penelitian terdiri dari masyarakat di Kecamatan Medan Tembung sebanyak 105 orang yang dipilih melalui consecutive sampling. Data yang digunakan adalah data primer dengan metode analisis berupa uji korelasi Chi-square. Hasil dan Diskusi. Data hasil penelitian dari 105 orang sampel didapatkan bahwa terdapat 70 orang (66,7%) dengan tingkat pengetahuan yang kurang, 100 orang (95,2%) dengan sikap yang baik, dan 78 orang (74,3%) dengan perilaku yang baik. Hasil analisis bivariat didapatkan 66 orang (62,8%) dengan tingkat pengetahuan kurang tetapi memiliki sikap baik 52 orang (49,5%), dengan tingkat pengetahuan kurang tetapi perilakunya baik, sehingga berdasarkan karakteristik responden tersebut didapatkan hubungan yang bermakna antara tingkat pendidikan dengan tingkat pengetahuan dengan nilai p = 0,042 dan pekerjaan dengan perilaku didapatkan nilai p = 0,009 responden. Kesimpulan. Tidak ada hubungan antara tingkat pengetahuan tentang penggolongan obat tradisional di Indonesia dengan sikap dan perilaku masyarakat di Kecamatan Medan Tembung dikarenakan sebagian besar masyarakat masih menerapkan compliance. Introduction. Indonesia's biodiversity is very high, there are around 30,000 plant species in Indonesia that have medicinal properties or can be used as traditional medicine. Traditional medicine has long been an essential part of the medical system in Indonesia. In 2004, BPOM classified traditional medicines based on clinical trials into herbal medicines, standardized herbal medicines and phytopharmacies. Objective. Analyzing the relationship between the level of knowledge and community attitudes and behavior regarding the classification of traditional medicines in Indonesia in Medan Tembung District. Research method. This research is an analytical observational study with a cross-sectional approach. Research data was collected using a questionnaire instrument containing questions to measure the level of knowledge, attitudes and behavior. The research sample consisted of 105 people in Medan Tembung District who were selected through consecutive sampling. The data used is primary data with the analysis method in the form of the Chi-square correlation test. Results and Discussion. Research data from 105 sample people showed that there were 70 people (66.7%) with a poor level of knowledge, 100 people (95.2%) with good attitudes, and 78 people (74.3%) with good behavior. The results of the bivariate analysis showed that 66 people (62.8%) had a low level of knowledge but had a good attitude, 52 people (49.5%), with a low level of knowledge but good behavior, so that based on the characteristics of these respondents, a significant relationship was found between the level of education and level of knowledge with a value of p = 0.042 and work with behavior obtained a value of p = 0.009 for respondents. Conclusion. There is no relationship between the level of knowledge about the classification of traditional medicines in Indonesia and the attitudes and behavior of the people in Medan Tembung District because the majority of people still practice compliance.  
Prevalence of Pressure Injury in Inpatients at H. Adam Malik Hospital Medan in 2020-2022 Regina, Christanti; Arwina Dalimunthe, Dina; Siregar, Irma Sepala Sari; Kamal Kharrazi Ilyas
SCRIPTA SCORE Scientific Medical Journal Vol. 6 No. 1 (2024): SCRIPTA SCORE Scientific Medical Journal
Publisher : Talenta Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32734/scripta.v6i1.15602

Abstract

Background: Pressure injury is a frequently occurring health issue in healthcare environments, especially within hospitals. The risk is increased in hospital settings where patients are frequently confined to beds or wheelchairs. Objectives: This study evaluated the prevalence of pressure injury in regular inpatients at H. Adam Malik Hospital, Medan, from 2020 to 2022. Methods: This study employs a descriptive design with a cross-sectional research approach, describing all variables using secondary data from patient medical records. Results: The research findings indicate that the most common age group is 41-60  years old (28,4%), with females comprising the majority (52,9%). The primary diagnoses related to the occurrence of pressure injury is neurological disorders (25.5%). The most frequent location of injury is the buttocks region (45.1%), and the most prevalent stage of injury is stage III (36.3%), with the most common management approach being debridement (43.6%). Conclusion: In H. Adam Malik Hospital, Medan, from 2020 to 2022, pressure injury was mostly found at ages 41-60 years old, in women, the most prevalent underlying primary disease was neurological disorders, on the buttocks region, at stage III, and the most common management approach being debridement. Latar Belakang: Ulkus Dekubitus merupakan masalah kesehatan yang sering terjadi di lingkungan perawatan kesehatan, terutama di rumah sakit. Risiko ini meningkat di rumah sakit yang pasiennya sering terbaring di tempat tidur atau kursi roda. Tujuan: Mengetahui gambaran Ulkus Dekubitus pasien rawat inap reguler di RSUP H. Adam Malik Medan pada tahun 2020 - 2022. Metode: Penelitian ini merupakan studi deskriptif dengan rancangan penelitian cross-sectional yang seluruh variabel dilihat menggunakan data sekunder berupa rekam medis pasien. Hasil: Penelitian ini menunjukkan bahwa kelompok usia yang paling banyak adalah usia 41-60 tahun (28,4%), dengan mayoritas adalah perempuan (52,9%). Diagnosis utama yang berhubungan dengan terjadinya Ulkus Dekubitus adalah gangguan neurologis (25,5%). Lokasi ulkus yang paling sering adalah daerah bokong (45,1%), dan derajat ulkus yang paling banyak terjadi adalah stadium III (36,3%), dengan penatalaksanaan yang paling banyak dilakukan adalah debridemen (43,6%). Kesimpulan: Di RSUP H. Adam Malik Medan pada tahun 2020 hingga 2022, Ulkus Dekubitus umumnya dijumpai pada usia 41-60 tahun, wanita, diagnosis utama gangguan neurologis, lokasi bokong, derajat III, dan tata laksana debridemen.
Peranan Mikrobiota Usus Manusia Golongan Bakteri Asam Laktat Sebagai Sumber Produksi Potensial dalam Manajemen Terapi Diabetes Melitus Tipe 1 pada Anak Amalia, Nindy Putri; Alparisi, Bima Diokta; Dimas, Riski; Anggraini, Dewi
SCRIPTA SCORE Scientific Medical Journal Vol. 6 No. 1 (2024): SCRIPTA SCORE Scientific Medical Journal
Publisher : Talenta Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32734/scripta.v6i1.15696

Abstract

Pendahuluan: Diabetes melitus tipe-1 (DMT-1) adalah penyakit autoimun kronis yang menyebabkan tubuh tidak dapat memproduksi insulin dalam kadar yang cukup. Menurut international diabetes federation (IDF) melaporkan secara global penderita diabetes melitus tipe-1 mencapai 8,75 juta orang dimana sebanyak 1,52 juta orang (17%) berusia di bawah 20 tahun. Angka mortalitas mencapai 18.105 kematian dari jumlah insiden 1,55 juta. Sedangkan di Indonesia jumlah kasus ini mencapai 41.817 penduduk sehingga menempati posisi teratas di ASEAN. Oleh karena itu, diperlukan sebuah inovasi manajemen terapi diabetes melitus tipe-1 terkhususnya pada anak yang memiliki keunggulan baik dalam pengobatan maupun produksi. Metode: Studi ini berupa kajian literatur yang bersumber dari beberapa pencarian internet yakni PubMed, Science Direct, ProQuest, Lancet, Google Schoolar, Garuda, Sage, dan EBSCOHost. Kajian ini disusun melalui beberapa tahap diantaranya identifikasi, skrining, dan pemenuhan kriteria inklusi dan eksklusi. Terdapat 8 artikel dari 611 artikel yang memenuhi kriteria. Pembahasan: Beberapa bakteri kelompok asam laktat sudah diuji klinis dan didapatkan hasil yang berpengaruh pada kontrol glikemik pasien diabetes melitus tipe-1. Perbaikan ditunjukkan pada kadar gula darah puasa, 2 jam postprandial, HbA1C, bahkan juga mempengaruhi C-peptida dan kadar insulin yang dibutuhkan pasien diabetes melitus tipe-1. Rute pemberian probiotik yang dilakukan juga cukup sederhana melalui oral, kecuali pada intervensi penggunaan fecal microbiota transplantation melalui injeksi. Kesimpulan: Bakteri asam laktat mempengaruhi kadar gula darah pasien, HbA1C, C-peptida, dan kadar insulin yang dibutuhkan pasien. Interval waktu pemberian probiotik juga mempengaruhi efek klinis yang diharapkan. Introduction: Type-1 diabetes mellitus (T1DM) is a chronic autoimmune disease that causes the body to not produce enough insulin. According to the International Diabetes Federation (IDF), globally, there are 8.75 million people with type 1 diabetes mellitus, with 1.52 million (17%) of them being under 20 years old. The mortality rate reaches 18,105 deaths out of 1.55 million incidents. Meanwhile, in Indonesia, the number of cases reaches 41,817, placing it at the top position in ASEAN. Therefore, an innovative management approach for type 1 diabetes mellitus therapy, especially in children, is needed, which excels both in treatment and production. Methods: This study is a literature review sourced from several internet searches including PubMed, Science Direct, ProQuest, Lancet, Google Scholar, Garuda, Sage, and EBSCOHost. The study was conducted through several stages including identification, screening, and fulfillment of inclusion and exclusion criteria. There are 8 articles out of 611 articles that met the criteria. Discussion:  Several lactic acid bacteria have been clinically tested and shown to have an effect on glycemic control in type 1 diabetes mellitus patients. Improvements are evident in fasting blood sugar levels, 2-hour postprandial levels, HbA1C, and even affect C-peptide and insulin levels required by type 1 diabetes mellitus patients. The administration route of probiotics is also quite simple, usually oral, except for interventions involving fecal microbiota transplantation via injection. Conclusion: Lactic acid bacteria affect patients' blood sugar levels, HbA1C, C-peptide, and the insulin levels required by patients. The timing interval of probiotic administration also affects the expected clinical effects.
Effects of the Parental Stepping Stone Triple P Program on Parental Mental Health and Disruptive Behavior in Children with Autism Spectrum Disorders: A Systematic Review and Meta-Analysis Simanjuntak, Janveri Balige; Sinaga, Erin Tasya; Manurung, Kelvin Wahana Anugrah
SCRIPTA SCORE Scientific Medical Journal Vol. 6 No. 1 (2024): SCRIPTA SCORE Scientific Medical Journal
Publisher : Talenta Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32734/scripta.v6i1.15727

Abstract

Background: Parents of children with Autism Spectrum Disorder (ASD) may face several challenges. Implementation of the Stepping Stone Triple P (SSTP) for parents proved to have an effect on reducing parents’ negative emotions and children’s disruptive behavior. However, some studies state otherwise. Objective: This study aims to assess the impact of the SSTP on parents’ negative emotions and disruptive behavior in children with ASD. Methods: Independent searching from databases conducted using a pre-registration search strategy until November 2023. The ROB 2.0 tool was used to assess the risk of bias in the results of the studies. The results were analyzed with vote counting and meta analysis. The quality of evidence was analyzed using GRADE and publication bias was checked using forest plots. Results: Vote-counting analysis from 11 studies (939 populations) show that SSTP has a positive impact. Meta-analysis was found that SSTP can reduce the level of negative emotions [MD 1.14 (95% CI -1.73 to -0.55) and I2 = 0%] and children's disruptive behavior [MD 6.31 (95% CI -7.84 to -4.78) and  I2 = 68 %] and still consistent after subgroup analysis resulting in 8 study arms. The quality of the evidence was moderate and publication bias was not detected. Conclusion: Most research supports that SSTP has an impact on reducing negative emotions and disruptive behavior in children with ASD. Further research with alternative parameters is still needed. To reduce bias, a randomization method according to the protocol must be applied. Latar Belakang: Orang tua anak dengan Autism Spectrum Disorder (ASD) mungkin menghadapi beberapa tantangan. Penerapan Stepping Stone Triple P (SSTP) pada orang tua terbukti memberikan pengaruh dalam mengurangi emosi negatif orang tua dan perilaku disruptif anak. Namun, beberapa penelitian menyatakan sebaliknya. Tujuan: Penelitian ini bertujuan untuk menilai dampak SSTP terhadap emosi negatif orang tua dan perilaku disruptif anak penderita ASD. Metode: Peninjau secara independen mencari studi dari database menggunakan strategi pencarian pra-pendaftaran hingga November 2023. ROB 2.0 digunakan untuk menilai risiko bias hasil penelitian. Hasilnya dianalisis dengan vote counting dan meta analisis. Kualitas bukti dianalisis menggunakan GRADE dan bias publikasi diperiksa menggunakan Forest Plot. Hasil: Analisis penghitungan suara dari 11 penelitian (939 populasi) menunjukkan bahwa SSTP cenderung mengurangi emosi negatif pada orang tua yang memiliki anak ASD, perilaku mengganggu pada anak, dan disfungsi pengasuhan. Meta-analisis menemukan bahwa SSTP dapat menurunkan tingkat emosi negatif [MD 1.14 (95% CI -1.73 hingga -0.55) dan I2 = 0%], dan perilaku mengganggu anak [MD 6.31 (95% CI -7.84 hingga -4.78) dan I2 = 68 %] dan masih konsisten setelah analisis sub kelompok menghasilkan 8 kelompok penelitian. Kualitas buktinya moderat dan bias publikasi tidak terdeteksi. Kesimpulan: Sebagian besar penelitian mendukung bahwa SSTP berdampak pada pengurangan emosi negatif dan perilaku mengganggu pada anak ASD. Penelitian lebih lanjut dengan parameter alternatif masih diperlukan. Untuk mengurangi bias, metode pengacakan sesuai protokol harus diterapkan.
Relationship Between the Personal Hygiene and The Occurrence of Pityriasis Versicolor In Students of State Senior High School 1 Medan 2020 Nasution, Namira Afifah; Hazlianda, Cut Putri
SCRIPTA SCORE Scientific Medical Journal Vol. 6 No. 1 (2024): SCRIPTA SCORE Scientific Medical Journal
Publisher : Talenta Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32734/scripta.v6i1.15764

Abstract

Background: Pityriasis versicolor (PV) is a superficial fungal infection on the outermost layer of skin caused by Malassezia furfur or Pityrosporum orbiculare, this infection stays for a long time, mild, and mostly the inflammation affects the face, neck, body, upper arm, axilla, thigh, and groin. PV often found in tropical areas and attack all ages, but mostly found on teenager age between 16-20 years. Self-care maintenance could be done by maintaining the good personal hygiene, because a poor personal hygiene was the risk factor that trigger pityriasis versicolor. This study has an objective to find out whether there is a relationship between personal hygiene and pityriasis versicolor of State Senior High School 1 Medan students in 2020. This study was observational with cross sectional design, the sample for this study were 100 students in State Senior High School 1 Medan in 2020 by using simple random sampling. Data was collected using an online questionnaire. Based on data from chi square method, there is a result value p=0,027 (p≤0,05). There is a meaningful relationship between personal hygiene and pityriasis versicolor.   Pendahuluan: Pitiriasis versikolor adalah infeksi jamur superfisial pada lapisan tanduk kulit yang disebabkan oleh Malassezia furfur atau Pityrosporum orbiculare. Infeksi ini bersifat menahun, ringan, dan biasanya tanpa peradangan yang mengenai muka, leher, badan, lengan atas, ketiak, paha, dan lipatan paha. Pitiriasis versikolor banyak dijumpai di daerah tropis dan dapat menyerang semua usia, namun paling banyak pada remaja usia 16-20 tahun. Pemeliharaan perawatan diri dilakukan dengan menjaga higiene perseorangan yang baik karena higiene perseorangan yang buruk adalah faktor yang memicu pitiriasis versikolor Tujuan: Penelitian ini bertujuan untuk mengetahui hubungan antara higienitas dan pityriasis versicolor pada siswa SMAN 1 tahun 2020. Metode: Penelitian ini merupakan jenis penelitian observasional dengan rancangan cross sectional. Sampel pada penelitian ini siswa-siswi SMAN 1 Medan tahun 2020 sebanyak 100 dan menggunakan metode simple random sampling. Data yang diperoleh melalui pengisian kuesioner secara online. Hasil: Berdasarkan data yang didapati menggunakan motede chi square, didapati hasil nilai p=0,027 (p≤0,05). Kesimpulan: Terdapat hubungan yang bermakna antara higiene perseorangan dengan kejadian pitiriasis versikolor.
Knowledge Level on Milk Protein Consumption Towards Acne Vulgaris for Gym Users Akmal, Mohammad Anis; Hazlianda, Cut Putri
SCRIPTA SCORE Scientific Medical Journal Vol. 6 No. 1 (2024): SCRIPTA SCORE Scientific Medical Journal
Publisher : Talenta Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32734/scripta.v6i1.15843

Abstract

Background: Acne vulgaris (AV) is a chronic inflammatory disease of the pilosebaceous unit, with a polymorphic clinical picture consisting of various skin disorders. Whey protein is also associated with potential acne triggers and is used as a supplement by young people trying to increase muscle mass. Objectives: To find out the description of the knowledge of gym users on the relationship between consuming milk protein and the incidence of acne vulgaris. Methods: This research is a descriptive study using a cross-sectional study approach. The sample was selected using a non-probability sampling technique, namely consecutive sampling with a sample size of 67 people using a questionnaire. Results: 67 gym users were selected as samples where the knowledge in the good category was as many as 3 people (4,5%), followed by the adequate category with the number of 24 people (35,8%) and the less category of 40 people (59,7%). Most sources of information obtained about the relationship between consuming milk protein to the incidence of acne vulgaris are from social media. Conclusion: The level of knowledge of gym users at the Grand Olympus Gym regarding the relationship between consuming milk protein and the incidence of acne vulgaris in general less knowledge. Latar Belakang: Akne vulgaris (AV) adalah penyakit peradangan kronis dari unit pilosebasea, dengan gambaran klinis polimorfik yang terdiri dari berbagai gangguan kulit. Whey protein dikaitkan dengan potensi pemicu jerawat dan digunakan sebagai suplemen oleh usia muda yang mencoba meningkatkan massa otot. Tujuan: Untuk mengetahui gambaran pengetahuan para pengguna gym tentang hubungan antara mengonsumsi protein susu dengan kejadian akne vulgaris. Metode: Penelitian ini merupakan studi deskriptif dengan menggunakan pendekatan studi potong lintang. Sampel dipilih menggunakan teknik non-probability sampling yaitu consecutive sampling dengan jumlah sampel sebanyak 67 orang dengan menggunakan kuesioner. Hasil: Sebanyak 67 pengguna gym dipilih sebagai sampel dimana pengetahuan dengan kategori baik sebanyak 3 orang (4,5%), diikuti kategori cukup dengan jumlah 24 orang (35,8%) dan kategori kurang sebanyak 40 orang (59,7%). Sebagian besar sumber informasi yang didapatkan tentang hubungan antara mengonsumsi protein susu dengan kejadian akne vulgaris berasal dari media sosial. Kesimpulan: Tingkat pengetahuan pengguna gym di Grand Olympus Gym mengenai hubungan antara mengonsumsi protein susu dengan kejadian jerawat (acne vulgaris) secara umum berpengetahuan kurang.

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