cover
Contact Name
Mohammad Saifur Rohman
Contact Email
hsj@ub.ac.id
Phone
+628973247705
Journal Mail Official
hsj@ub.ac.id
Editorial Address
Department of Cardiology and Vascular Medicine, Dr. Saiful Anwar General Hospital, 3rd Floor CVCU Jl. Jaksa Agung Suprapto No. 2, Malang, Indonesia
Location
Kota malang,
Jawa timur
INDONESIA
Heart Science Journal
Published by Universitas Brawijaya
Core Subject : Health, Science,
HEART SCIENCE is the official open access journal of Brawijaya Cardiovascular Research Center, Department of Cardiology and Vascular Medicine, Faculty of Medicine, Universitas Brawijaya, Malang, Indonesia. The journal publishes articles three times per year in January, May, and September. The journal is a peer reviewed publication and accepts articles for publication from across the world. HEART SCIENCE accepts and publishes articles in the English language only. The primary goal of this journal is to publish clinical and basic research relevant to cardiovascular medicine. The journal covers the following topics: clinical cardiology, interventional cardiology, intensive and acute cardiovascular care, vascular diseases, non-invasive cardiology, pediatric cardiology, cardiac nuclear medicine imaging, arrhythmia, cardiac prevention and rehabilitation, and cardiac surgery. Animal studies are also considered for publication in HEART SCIENCE. To serve the interest of both practicing clinicians and researchers, the journal provides platform or forum for research scholars, intellectuals, and cardiologists to reveal their views and research work for dialogue, education, and interaction to the entire world. HEART SCIENCE publishes original research, reviews, brief reports, case reports, case series, editorial, and commentary. HEART SCIENCE also publishes the special issues and abstracts of papers presented at the annual meeting of the Cardiological Society of Malang.
Articles 302 Documents
AF-CARE: The current approach in atrial fibrillation management Rizal, Ardian
Heart Science Journal Vol. 6 No. 2 (2025): The Complexity in the Management of Heart Rhythm Disorder
Publisher : Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.hsj.2025.006.02.1

Abstract

Despite improvements in treatment, atrial fibrillation (AF) continues to pose a serious threat to global health, with increasing rates of morbidity and mortality. By endorsing the AF-CARE approach, the 2024 ESC guidelines shift the paradigm from the conventional "CC to ABC" model and place more emphasis on patient empowerment, comorbidity management, and rhythm control. Important changes include promoting early catheter ablation for certain patients, as shown by the CABANA and EARLY-AF trials, and prioritising risk factor modification (such as obesity and sleep apnoea) as a therapeutic approach, backed by trials like LEGACY. The guidelines also emphasise patient-centred care, incorporating digital tools and education. The paradigm shift towards holistic AF management is highlighted in this editorial, which combines shared decision-making, lifestyle interventions, and technological innovation to enhance results.
Cardiac implantable electronic device infection - how to recognize and treat? Rochmawati, Icmi Dian; Rizal, Ardian
Heart Science Journal Vol. 6 No. 3 (2025): Advancements in Cardiac Imaging : Unlocking New Perspectives on the Heart Visua
Publisher : Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.hsj.2025.006.03.10

Abstract

Implantable Electronic Devices (CIEDs) have significantly transformed the treatment of various heart conditions. However, their growing use has been accompanied by an increase in device-related infections, posing a serious medical concern. Early identification of CIED infections is essential for prompt and effective treatment. Typical clinical signs include localized infection symptoms—such as redness, warmth, and tenderness around the implant site—as well as general symptoms like fever and fatigue. Diagnostic support also comes from laboratory tests, particularly elevated inflammatory markers. Management of these infections requires a coordinated, multidisciplinary approach. Timely removal of the infected device is critical, along with the administration of targeted antibiotics based on culture and sensitivity findings. In some instances, surgical removal of the entire device, including any leads, may be necessary. Preventing such infections is equally important and involves strict adherence to aseptic techniques during implantation and any subsequent procedures. Prophylactic antibiotics may also be warranted for patients at high risk. In summary, the successful management of CIED infections relies on early detection, accurate diagnosis, and a well-coordinated treatment plan. Preventive measures are vital in decreasing infection rates and ensuring the best possible outcomes for patients.
Valvular aspects from echocardiography in rheumatic heart disease Noverike, Nikhen; Anna Fuji Rahimah; Yogibuana, Valerinna; Karolina, Wella
Heart Science Journal Vol. 6 No. 3 (2025): Advancements in Cardiac Imaging : Unlocking New Perspectives on the Heart Visua
Publisher : Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.hsj.2025.006.03.5

Abstract

Rheumatic Heart Disease is a result of an autoimmune response to group A streptococcal infection and is globally impacted and prevalent in low- and middle-income countries, especially among children and young adults. It primarily affects the heart valves, leading to damage and dysfunction. The progression of RHD can vary, with some individuals experiencing mild symptoms while others may develop severe valve damage leading to heart failure. Echocardiography plays a crucial role in the diagnosis and monitoring of RHD, as it allows to visualize and assess the structural and functional abnormalities of the heart valves. Early detection through echocardiography screening is essential for timely intervention and management of RHD. It provides valuable information about the severity of valve damage and helps determine the most appropriate treatment approach, whether it involves medication or surgical intervention. The ability of echocardiography to provide information about volumes, flows, and pressures, and to acquire quantitative hemodynamic data, highlights its importance in the assessment of patients with RHD. In conclusion, echocardiography has revolutionized the way we diagnose, monitor, and manage rheumatic heart disease, and its importance in the medical field cannot be overstated. The continued integration of echocardiography into clinical practice will undoubtedly lead to improved outcomes for patients with RHD.
Coronary plaque assessment by coronary computed tomography angiography Indrihapsari, Pratiwi; Handari, Saskia Dyah
Heart Science Journal Vol. 6 No. 3 (2025): Advancements in Cardiac Imaging : Unlocking New Perspectives on the Heart Visua
Publisher : Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.hsj.2025.006.03.2

Abstract

Coronary computed tomography angiography (CCTA) is a widely used non-invasive diagnostic technique in medical practice. It effectively detects, quantifies, and characterizes coronary artery plaques. With advancements in CCTA imaging, the quantity and quality of atherosclerotic plaques can now be accurately evaluated. This technique is commonly utilized to rule out the possibility of coronary artery disease and precisely assess how the condition impacts the coronary vessels. CCTA is a valuable diagnostic tool that can help identify high-risk plaque features and recommend appropriate treatment measures. By comparing morphological aspects of stable lesions with those of susceptible plaques, CCTA can help identify characteristics such as the napkin-ring sign, low CT attenuation, positive remodeling, significant plaque volume, and spotty calcification, which have been linked to an increased risk of acute coronary syndrome. To standardize the reporting of patients who undergo CCTA and guide probable following actions in patient care, the Coronary Artery Disease Reporting and Data System (CAD-RADS) was created. This system ensures that patient reports are consistent, accurate, and valuable for guiding appropriate treatment and care.
Multimodality imaging in evaluation of cardiac masses Sihotang, Fransiska Anggreni; Handari, Saskia Dyah
Heart Science Journal Vol. 6 No. 3 (2025): Advancements in Cardiac Imaging : Unlocking New Perspectives on the Heart Visua
Publisher : Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.hsj.2025.006.03.8

Abstract

Cardiac masses are infrequently encountered in routine cardiology practice but often pose as a diagnostic challenge. Cardiac masses can be categorised as either neoplastic (benign and malignant) or non-neoplastic, and as either primary or secondary. The prognosis is contingent upon the identification of the mass, as treatment choices vary significantly. Histopathology remains the most dependable approach for diagnosing any cardiac tumour. Nevertheless, given its invasive characteristics, cardiac imaging plays a crucial role in diagnosing cardiac masses. The emergence of new imaging tools necessitates a multimodality strategy to assess intracardiac masses. This approach is crucial for non-invasive evaluation before considering surgical planning or oncological treatment. This article aims to compare the different imaging techniques, particularly echocardiography, cardiovascular magnetic resonance, cardiac computed tomography, and nuclear imaging, in terms of their clinical applications in the evaluation of cardiac masses and to determine distinctive features on these modalities for the most prevalent intracardiac masses.
Multi-modality cardiac imaging in aorta and aortic valve from evaluation to post treatment Suprapta, Aloysius Yuwono; Handari, Saskia Dyah
Heart Science Journal Vol. 6 No. 3 (2025): Advancements in Cardiac Imaging : Unlocking New Perspectives on the Heart Visua
Publisher : Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.hsj.2025.006.03.4

Abstract

Aorta and aortic valve disease are crucial but usually found unintentionally while doing imaging evaluation. Genetic and non-genetical issues can be the source of the disease. Proper evaluation using multimodality of imaging can give an early diagnosis and proper treatment according to recent situation.  Aortic disease and aortic valve disease can result from genetic and non-genetic problems. Echocardiography (transthoracic or transesophageal) can be the first modality to evaluate this disease. Further modalities (computed tomography angiography, magnetic resonance imaging, and positron electromagnetic) can be used as supporting data to make more accurate analyses for diagnosis and evaluation post-treatment. Although they give more accurate images, there are some limitations in each modality. Knowing the benefits and limitations of each modality can make better use of the tools. Multimodality imaging is enhancing in detection of aortic disease and aortic valve disease. Understanding the benefits and limits of each imaging technique is essential for determining the best modality
Quality of life assessment in patients after permanent pacemaker implantation at Haji Adam Malik Hospital Medan Khairunnisah, Dina; Ali Nafiah Nasution; Refli Hasan; Nizam Zikri Akbar; Anggia Chairuddin Lubis; Abdul Halim Raynaldo
Heart Science Journal Vol. 6 No. 3 (2025): Advancements in Cardiac Imaging : Unlocking New Perspectives on the Heart Visua
Publisher : Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.hsj.2025.006.03.15

Abstract

Background: PPM implantation is used to send electrical impulses to the heart muscle to correct heart rhythm disturbances also known as cardiac arrythmia. Assessing the patient's quality of life after a PPM implantation is crucial for predicting the therapy's effectiveness and success. Objectives: This study aims to assess the quality of life of patients following pacemaker implantation by using the SF-36 questionnaire. Methods: A cross-sectional study conducted from January 2021 to July 2023 on 60 outpatients with a minimum duration of PPM implantation of 6 months in the cardiology department of H. Adam Malik Hospital Medan. Patient’s quality of life was assessed based on the SF-36 questionnaire. Subjects then were grouped based on age, gender, PPM duration and location, as well as other echocardiographic parameters that may affect patient’s quality of life after PPM implantation. Results: There were 60 patients included in this study. Majority of patients were male (56.7%) with an average age of 67.98 ± 10.95 years old and most patients had comorbidities (81.7%). The majority of patients (93.3%) had a single-chamber permanent pacemaker implanted, with 68.3% of these devices’ ventricular leads positioned in the non-apical segment of the heart.  After assessing the quality of life, we found there’s a relationship between age, gender, and PPM lead locations with nearly all SF-36 domains (p<0.05). Additionally, there was a significant association between comorbidities and SF-36 scores, including physical function, physical limitations, and emotional limitations (p<0.05). There was a significant association between ejection fraction and SF-36 scores, including physical function, role limitations due to physical health problems, vitality, social function, bodily pain and general health. However, no relationship was found between IMT and PPM implantation duration with SF-36 scores (p>0.05). Conclusion: We identified a relationship between age, gender, comorbidities, PPM lead location, and ventricular ejection fraction with the quality of life of patients following PPM implantation
Diagnosis and differentiation of pathological concentric left ventricular hypertrophy Millisani, Hayla Iqda; Karolina, Wella
Heart Science Journal Vol. 6 No. 3 (2025): Advancements in Cardiac Imaging : Unlocking New Perspectives on the Heart Visua
Publisher : Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.hsj.2025.006.03.6

Abstract

Identifying the diagnosis and differentiation of concentric left ventricular hypertrophy (LVH) can be crucial, as the various etiology ofter similar characteristics and morphology. Concentric left ventricular hypertrophy (LVH) is the term used to describe the enlargement of the left ventricle (LV), the increase in the mass and thickness of the LV wall which can occur in response to pressure overload. The most common etiology of concentric hypertrophy include the systemic hypertension, aortic stenosis and hypertrophic cardiomyopathy (associated with sarcomere mutations, infiltrative cardiac diseases, and storage disorders). Cardiac imaging is the predominant modality for visualizing and quantifying LVH in clinical practice and often collaborates with an established diagnosis. Echocardiography, the primary imaging modality, enables a thorough evaluation of left ventricular systolic and diastolic function. Cardiovascular magnetic resonance offers further benefits by correctly measuring left ventricular and right ventricular sizes and mass, as well as characterizing myocardial tissue properties. These measurements can provide valuable insights for making a final diagnosis.
Non-invasive multimodality cardiac stress test imaging: Role of echocardiography, cardiac computed tomography, cardiac magnetic resonance, and nuclear medicine Kahadi, Cik; Handari, Saskia Dyah
Heart Science Journal Vol. 6 No. 3 (2025): Advancements in Cardiac Imaging : Unlocking New Perspectives on the Heart Visua
Publisher : Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.hsj.2025.006.03.3

Abstract

Coronary artery disease, or CAD, is the major cause of mortality and morbidity globally, with significant socioeconomic impact. Based on European Society of Cardiology or ESC guidelines in Chronic Coronary Syndrome (CCS), multimodality imaging strategies are highly suggested in evaluating the patient who suspected CAD. Non-invasive imaging modalities can assess the anatomy of coronary artery by using Coronary Computed Tomography Angiography (CCTA) or assess functional stress testing with inducible myocardial ischemia by using Stress Echocardiography (SE), Myocardial CT Perfusion (CTP), Cardiac Magnetic Resonance (CMR), Single Photon Emission Computed Tomography (SPECT), or Positron Emission Tomography (PET). Nowadays, it’s important to recognize the limitations and capabilities of each imaging method, especially before selecting a functional testing focused on ischemia compared to an anatomy of coronary imaging. This paper describes an overview of non-invasive imaging modalities for the general diagnosis of CAD patients. Non-invasive multimodality cardiac stress test imaging is enhancing the diagnosis of significant stenosis of the coronary artery. Understanding the benefits and limits of each imaging is essential for determining the best modality we used.
Hype or hope: The role of alcohol septal ablation in improving outcomes for young patients with obstructive hypertrophic cardiomyopathy: A case series Saputri, Vemmy Lian; Rizal, Ardian; Rahimah, Anna Fuji; Karolina, Wella; Yogibuana, Valerinna; Prasetya, Indra
Heart Science Journal Vol. 6 No. 3 (2025): Advancements in Cardiac Imaging : Unlocking New Perspectives on the Heart Visua
Publisher : Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.hsj.2025.006.03.19

Abstract

Background: Hypertrophic cardiomyopathy (HCM) is a disease that has a poor prognosis and a higher likelihood of death in young people. Alcohol septal ablation (ASA) is a minimally invasive procedure that involves the injection of ethanol through a septal perforator to lead to infarction of the hypertrophied septum. This case series aims to present data on the beneficial effects of ASA in promoting hope for enhanced outcomes in young patients with HCM. Case: Patient 1: A 32-year-old male with HCM has been suffering from chest discomfort and atrial fibrillation since 2020. Echocardiography detected an increased obstruction in the left ventricular outflow tract (LVOT), resulting in a gradient of 104 mmHg. The patient underwent ASA to decrease the gradient to 37 mmHg, reducing hospitalizations throughout a 12-month follow-up period. Patient 2: A 27-year-old female diagnosed with HCM has been frequently suffering episodes of near syncope and shortness of breath with light activity over the past 6 months. The echocardiography findings showed a significant increase in the resting gradient in the LVOT. Following ASA, the resting gradient decreased to 54 mmHg during a 3-month follow-up. The patient did not suffer further near syncope events, and her NYHA functional class improved throughout a 9-month follow-up period. Conclusion: The effectiveness of ASA as a treatment option is hope for young patients with obstructive HCM, which is demonstrated in this case series, leading to relieving symptoms, reduced repeated hospitalization, and improved functional capacity.

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All Issue Vol. 6 No. 4 (2025): The Pursuit of Precision: Navigating Risks, Refining Diagnosis, and Securing Lo Vol. 6 No. 3 (2025): Advancements in Cardiac Imaging : Unlocking New Perspectives on the Heart Visua Vol. 6 No. 2 (2025): The Complexity in the Management of Heart Rhythm Disorder Vol. 6 No. 1 (2025): Challenges in Managing Acute Heart Failure Vol. 6 No. Suppl_July (2025): Supplement Issue : Indonesian Acute Coronary Syndrome Summit in Conjun Vol. 5 No. 4 (2024): The Current Perspective About Cardiometabolic Disease Vol. 5 No. 3 (2024): The Science and Art of Revascularization in Acute Coronary Syndrome Vol. 5 No. 2 (2024): Challenges in the Management of Congenital Heart and Structural Heart Diseases Vol. 5 No. 1 (2024): Inflammation and Cardiovascular Disease Vol. 4 No. 4 (2023): The Science and Art of Caring for Critically III Patients in Intensive Cardiac Vol. 4 No. 3 (2023): The Essensial Role of the Metabolic Syndrome in the Development of Cardiovascul Vol 4, No 2 (2023): Dealing with the Complexity of the Wide Spectrum of Cardiovascular Disease Vol 4, No 1 (2023): Optimizing Outcome in Acute Cardiac Care Vol. 4 No. 1 (2023): Optimizing Outcome in Acute Cardiac Care Vol. 3 No. 4 (2022): Prevention, Screening dan Rehabilitation : The Back Bone of Quality Care Improv Vol 3, No 4 (2022): Prevention, Screening dan Rehabilitation : The Back Bone of Quality Care Improve Vol. 3 No. 3 (2022): Cardiovascular Disease in Young Adulthood: Who, When, and How to Screen? Vol 3, No 3 (2022): Cardiovascular Disease in Young Adulthood: Who, When, and How to Screen? Vol 3, No 2 (2022): Improving ST-Elevation Myocardial Infraction Patients Prognosis Vol 3, No 1 (2022): Assesment and Outcome of Coronary Artery Disease in the Reperfusion Era Vol 2, No 4 (2021): Management of Thrombosis in Covid-19 Patient with Cardiovascular Disease Vol 2, No 3 (2021): The Science and Art of Myocardial Revascularization Vol 2, No 2 (2021): Dealing with Vascular Disease Vol 2, No 1 (2021): How to Diagnose Heart Failure and Deal with The Treatment Complexity Vol 1, No 4 (2020): Acute Coronary Syndrome in Daily Practice : Diagnosis, Complication, and Managem Vol 1, No 3 (2020): Management of Coronary Artery Disease: From Risk Factors to The Better Long-Term Vol 1, No 2 (2020): The Assessment of Diagnostic and Treatment Modality in Heart Failure Vol 1, No 1 (2020): The Importance of Adherence to The Guidelines More Issue