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Mohammad Saifur Rohman
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Department of Cardiology and Vascular Medicine, Dr. Saiful Anwar General Hospital, 3rd Floor CVCU Jl. Jaksa Agung Suprapto No. 2, Malang, Indonesia
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Heart Science Journal
Published by Universitas Brawijaya
ISSN : 27219976     EISSN : 27219984     DOI : http://dx.doi.org/10.21776/ub.hsj.2020.001.01
Core Subject : Health, Science,
Health Professions Immunology & microbiology Medicine & Pharmacology
HEART SCIENCE is the official open access journal of Brawijaya Cardiovascular Research Center, Department of Cardiology and Vascular Medicine, Faculty of Medicine, Universitas Brawijaya, Malang, Indonesia. The journal publishes articles three times per year in January, May, and September. The journal is a peer reviewed publication and accepts articles for publication from across the world. HEART SCIENCE accepts and publishes articles in the English language only. The primary goal of this journal is to publish clinical and basic research relevant to cardiovascular medicine. The journal covers the following topics: clinical cardiology, interventional cardiology, intensive and acute cardiovascular care, vascular diseases, non-invasive cardiology, pediatric cardiology, cardiac nuclear medicine imaging, arrhythmia, cardiac prevention and rehabilitation, and cardiac surgery. Animal studies are also considered for publication in HEART SCIENCE. To serve the interest of both practicing clinicians and researchers, the journal provides platform or forum for research scholars, intellectuals, and cardiologists to reveal their views and research work for dialogue, education, and interaction to the entire world. HEART SCIENCE publishes original research, reviews, brief reports, case reports, case series, editorial, and commentary. HEART SCIENCE also publishes the special issues and abstracts of papers presented at the annual meeting of the Cardiological Society of Malang.
Arjuna Subject : Kedokteran - Cardiology and Cardiovascular Medicine
Articles 363 Documents
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A systematic review and meta-analysis of drug-coated balloons versus drug-eluting stents in de novo and in-stent restenosis coronary bifurcation lesions Dzikrul Haq Karimullah, Muchammad; Saputra, Pandit Bagus Tri; Alkaff, Firas Farisi; Oktaviono, Yudi Her; Nugraha, Ricardo Adrian; Faizah, Novia Nurul; Widiarti, Wynne; Aufazhafarin, Nadhifa Tanesha; Doman, Zahras Azimuth; Sahara, Rendy Asmaradhana; Niazta, Nisa Amnifolia
Heart Science Journal Vol. 7 No. 3 (2026): Predicting Restenosis in Coronary Artery Disease
Publisher : Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.hsj.2026.007.03.6

Abstract

Background: Coronary bifurcation lesions are notoriously difficult to treat percutaneously and may require advanced techniques. Drug-eluting balloons (DCBs) have several advantages over drug-eluting stents (DESs), including the ability to maintain arterial physiology, reduce the risk of stent thrombosis, and eliminate the need for permanent metal implants. However, it remains uncertain which treatment will work best. Objective: This study evaluated DCBs and DESs in coronary bifurcation lesions using subgroup analyses based on lesion type and location. Methods: We searched scientific databases for relevant publications up until May 31, 2025. In order to synthesise the results, a random-effects model was employed. To determine the possibility of bias, the ROBINS-I was utilized, and to measure the level of heterogeneity across the studies, the I³ statistic was used. Results were analyzed clinically and angiographically. This subgroup analysis focused on the position of the bifurcation and the kind of lesion (new, internal, or all sites). Result: Eleven research were deemed eligible for inclusion. There was a trend toward fewer major adverse cardiac events (MACE) with DCB compared to DES in the whole cohort, however the trend was not statistically significant (OR0.77, 95% CI0.58-1.02; p=0.07; I²=0%). Both major adverse cardiac events (MACE) and target lesion revascularization (TLR) were significantly reduced in de novo bifurcations when DCB was used (OR0.61, 95% CI 0.41-0.89; p=0.01). Myocardial infarction, target vessel revascularization, in-stent thrombosis, and cardiac mortality were not significantly different among groups. Both the early and late lumen loss and gain seen on angiograms were within the normal range. Conclusion: In de novo bifurcation lesions, DCB demonstrates reduced MACE and TLR versus DES, supporting its role as a stent-free alternative. Randomized controlled trials with greater sample sizes and prolonged follow-up are warranted.
Multiple left ventricular thrombus following coronary artery bypass graft: An uncommonly documented case report Hutomo, Malombassi Dharmawan Hadiwidjojo; Kurnianingsih, Novi; Muttaqin, Chaidar; Widito, Sasmojo
Heart Science Journal Vol. 7 No. 3 (2026): Predicting Restenosis in Coronary Artery Disease
Publisher : Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.hsj.2026.007.03.19

Abstract

Background: Left Ventricular Thrombus (LVT) formation after Coronary Artery Bypass Grafting (CABG) is infrequent but may result in life-threatening embolic events. The occurrence of LVT following CABG is linked to impaired left ventricular function, regional wall motion abnormalities (RWMAs), hypercoagulability, and an increased inflammatory response subsequent to heart surgery. The interplay of these factors predisposes patients to thrombus development, particularly in those with a history of myocardial infarction, reduced left ventricle ejection fraction (LVEF), pre-existing endothelial injury, or hypercoagulable conditions. Case Presentations: A 65-year-old female with reduced LVEF, 36% by biplane, and RWMAs developed multiple LVT following CABG, as revealed by serial transthoracic echocardiography on postoperative day 6. There was no intracardiac thrombus confirmed preoperatively by transthoracic echocardiography and intraoperatively by transesophageal echocardiography. On follow-up, hypercoagulable risk factors was observed, and adenocarcinoma was diagnosed by bone survey and ultrasound-guided biopsy, suggestive of a metastatic process. A complete resolution of multiple LVTs was achieved after three months of administration of warfarin 2mg daily. Conclusions: This case underscores the importance of echocardiography surveillance among high-risk populations postoperatively. Prompt identification and early initiation of anticoagulants showed to be beneficial in hypercoagulable conditions in carcinoma patient as reported in this case.
Predicting severity and restenosis in coronary artery disease Firman, Doni
Heart Science Journal Vol. 7 No. 3 (2026): Predicting Restenosis in Coronary Artery Disease
Publisher : Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.hsj.2026.007.03.1

Abstract

Despite significant advances in percutaneous coronary intervention (PCI), in-stent restenosis (ISR) remains a major challenge in contemporary coronary intervention. As a complication that is caused by multiple factors, identification of underlying mechanisms is crucial to prevent the event of ISR. A recent data highlights the Tp-e/QTc ratio on a standard ECG as a simple, non-invasive surrogate for SYNTAX score, suggesting a simple, non-invasive marker for coronary lesion complexity. Integrating pre-procedural assessment of coronary disease severity with post-procedural identification of independent risk factors may improve risk stratification and potentially reduce the incidence of ISR. Combined with aggressive secondary prevention strategies, this comprehensive approach may contribute to improved long-term outcomes after PCI.

Page 37 of 37 | Total Record : 363

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