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Contact Name
Aen Fariah
Contact Email
aenfariah1995@gmail.com
Phone
+6282214018102
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healthsains@gmail.com
Editorial Address
http://jurnal.healthsains.co.id/index.php/jhs/about/editorialTeam
Location
Kota cirebon,
Jawa barat
INDONESIA
Jurnal Health Sains
ISSN : 27236927     EISSN : 27234339     DOI : http://doi.org/10.36418
Core Subject : Health,
Jurnal Health Sains adalah jurnal yang diterbitkan sebulan sekali oleh Ridwan Institute. Jurnal Health Sains akan menerbitkan artikel ilmiah dalam lingkup ilmu kesehatan. Artikel yang diterbitkan adalah artikel dari penelitian, studi atau studi ilmiah kritis dan komprehensif tentang isu-isu penting dan terkini atau ulasan buku-buku ilmiah.
Articles 764 Documents
Effect of Curcuma longa Extract as Adjuvant Therapy on IL-6 Serum Levels in Leprosy Type 1 Reaction Patients Syifa Nurisma Putri; Farmaditya Eka Putra Mundhofir; Renni Yuniati; Noor Wijayahadi; Yora Nindita
Jurnal Health Sains Vol. 5 No. 6 (2024): Journal Health Sains
Publisher : Syntax Corporation Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46799/jhs.v5i6.1301

Abstract

Type 1 leprosy reaction / Reversal reaction (RR) is an inflammatory episode in existing leprosy lesions and aggravates the pain rate. Long-term therapy with steroids causes a variety of side effects, so an adjuvant therapy alternative is needed to alleviate steroid use. Curcuma longa rhizome extract has become an anti-inflammatory therapy choice in various previous inflammatory diseases. This study aims to determine the anti-inflammatory effect of Curcuma longa rhizome extract as an adjuvant therapy for reversal reaction patients by analyzing serum levels of IL-6 as a marker of inflammation. The pre and post-test randomized single-blinded controlled trial was conducted on two groups, namely control (RR patients with steroid therapy & placebo) and treatment (steroid therapy & Curcuma longa rhizome extract 1 gram/day). IL-6 serum levels were analyzed from sampling before and after the intervention for one month. The serum levels of IL-6 post-test in the control group were significantly higher than those of the pre-test. The treatment group showed lower serum levels of IL-6 post-test compared to pre-test, although there was no significant difference. Curcuma longa rhizome extract 1 gram/day for one month as adjuvant therapy for patients with type 1 leprosy reaction did not significantly reduce serum IL-6 levels.
Surrogate Biomarker to Identify Obesity and Predict Cardiovascular Disease Risk: A Systematic Review Farchan Azzumar; Helda Helda; Qonita Nur Salamah; Rahma Dewi Handari; Ramadhani Ramadhani; Reihana Ramadlani Ibna; Yanti Herawati
Jurnal Health Sains Vol. 5 No. 7 (2024): Journal Health Sains
Publisher : Syntax Corporation Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46799/jhs.v5i7.1302

Abstract

The study investigates the relationship between obesity and cardiovascular disease (CVD) risk, comparing the use of body mass index (BMI) versus other biomarkers in predicting CVD risk among obese individuals. It conducts a systematic literature review following the PRISMA guidelines, searching databases for relevant articles published from 2017-2022. The review analyzes 12 eligible articles and finds that factors beyond just BMI, such as genetics, physical activity, metabolic disorders, previous heart disease history, nutrition, fat distribution, and changes in BMI, can significantly impact the prognosis of heart disease in obese individuals. Importantly, the study shows that measures of fat distribution, like waist-to-height ratio, waist circumference, log-transformed body shape index (LBSIZ), and the ratio of visceral adipose tissue (VAT) to subcutaneous adipose tissue (SAT), are superior to BMI in predicting CVD risk among those with obesity. The key takeaway is that while obesity is strongly linked to CVD risk, BMI alone often fails to predict that risk accurately. Fat distribution measures may be a more effective tool for identifying obesity status and predicting associated CVD risk compared to relying solely on BMI.
Analysis of Impact and Sustainability in Chronic Diseases Prevention Program in XXX Highschool Balikpapan (Systematic Review) Tarninda, Andi Amirul; Erwandi, Dadan
Jurnal Health Sains Vol. 5 No. 7 (2024): Journal Health Sains
Publisher : Syntax Corporation Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46799/jhs.v5i7.1309

Abstract

A healthy lifestyle requires discipline. It's not easy, particularly adolescent who feel free and are looking for their existence. Its implementaiton needs to be applied to adolescent due to many cases of chronic diseases developing among them, following their lifestyle. Sedentary/lazy to move, smoking, alcohol, lack of rest and not being able to manage mental health. Generally, adolesecent at the educational level of Junior and Senior High School. The objective of this study is to analyze aspects of the impact and sustainability of chronic disease prevention programs for adolescents. This study is a systematic review using the PRISMA (Preferred Reporting Items for Systematic Reviews & Meta Analyses) method combined with open-source search engine. The database used for searching data and information is PubMed. The keywords used during the search process are "Prevention of Chronic Disease" AND "Chronic Disease" OR "Non-communicable Disease" OR "Infectious Disease" AND “Impact of Chronic Diseases” AND “Teenagers” OR “Adolescents” AND “School”. The most variable aspects of disease prevention are more information related to chronic diseases, knowledge, attitudes and stakeholder support. The CERDIK program provides knowledge, education and information among adolescents. These factors must be taken into consideration to improve lifestyle, maintain health so that you are not vulnerable to health problems during the teenage period
Herbal Soap Formulation as Anti-Bacterial in the Context of Increasing the Community's Healthy Living Movement Nuryati, Anik; Setiawan, Budi; Martsiningsih, M. Atik
Jurnal Health Sains Vol. 5 No. 7 (2024): Journal Health Sains
Publisher : Syntax Corporation Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46799/jhs.v5i7.1317

Abstract

Plants have long been used by Indonesian communities for medicinal purposes, including herbal soaps. The number of herbal soap producers has increased, offering various types made from natural ingredients such as lemongrass, clove, and cinnamon. However, the concentration of essential oils in herbal soaps can vary significantly across brands. This study aimed to formulate an herbal soap as an antibacterial agent by determining the minimum concentration of essential oils (clove, cinnamon, and lemongrass) needed to inhibit the growth of Staphylococcus epidermidis and Pseudomonas aeruginosa. The research employed a Post-test Only Control Group Design and was conducted at the Microbiology Laboratory of Health Analysts in Yogyakarta from January to October 2020. The study tested essential oils at concentrations of 0.5%, 1.0%, 1.5%, and 2.0%. The inhibition zones were measured to evaluate effectiveness. Results showed that the inhibition zones for lemongrass oil at concentrations of 0.5%, 1%, 1.5%, and 2% against Pseudomonas aeruginosa were 6.85, 7.61, 7.89, and 8.92 mm, respectively. Cinnamon oil exhibited larger inhibition zones against both Pseudomonas aeruginosa and Staphylococcus epidermidis. Clove oil had less antibacterial effectiveness compared to cinnamon. Cinnamon oil at 2.00% concentration was very effective against Staphylococcus epidermidis, while 1.50% concentration was adequate for Pseudomonas aeruginosa.
Cutler Beard Procedure for Bilateral Upper Eyelid Coloboma in Charge’s Syndrom: Surgical Outcome Aulia, Nur; Pagarra, Halimah; Amir, Suliati P.; Pratiwi, A.; Akib, Marliyanti N.
Jurnal Health Sains Vol. 5 No. 7 (2024): Journal Health Sains
Publisher : Syntax Corporation Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46799/jhs.v5i7.1321

Abstract

Ocular coloboma is one of the anomalies that commonly seen in CHARGE syndrome. This syndrome is an autosomal dominant malformation which includes six major features: coloboma, heart defect, atresia of the choanae, retarded growth and development delay, genital hypoplasia, ear anomalies. Cutler-Beard procedure is one of the major technic when a total or near total upper eyelid is missing. To report the surgical outcome in bilateral upper eyelid coloboma in CHARGE syndrome patient after Cutler Beard’s procedure. A 8 month-old boy presented to the hospital with bilateral upper eyelid coloboma since birth. Other clinical manifestations including bilateral optic nerve coloboma, external ear anomalies, bilateral undecensus testis, growth and developmental delay, and CHARGE facies which were consistent with 2 and 4 major and minor diagnostic criteria. The patient underwent eyelid reconstruction by using Cutler Beard procedure in both of eyes. Cutler Beard procedure may be used as the primary reconstruction method in bilateral upper eyelid coloboma in CHARGE syndrome.
Standardized Nutritional Care Process in Type 2 Diabetes Mellitus Patients with Stroke: Low Carbohydrate, Fat and Salt Diet Bardiati, Endah; Binasari, Binasari; Kurniasari, Fuadiyah Nila
Jurnal Health Sains Vol. 5 No. 7 (2024): Journal Health Sains
Publisher : Syntax Corporation Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46799/jhs.v5i7.1327

Abstract

Diabetes Melitus merupakan salah satu penyakit tidak menular dengan proporsi tertinggi di Indonesia. Menurut data Riskesdas 2018, preval__ensi diabetes mellitus terus mengalami peningkatan. Pengaturan Peningkatan kadar glukosa dapat menimbulkan risiko kerusakan mikrovaskular (retinopati, nefropati, dan neuropati) serta dapat menimbulkan penyakit kardiovaskular, stroke, pembuluh darah perifer dan penurunan kualitas hidup. Empat pilar utama penatalaksanaan diabetes melitus meliputi edukasi, diet, latihan jasmani/aktivitas fisik dan obat. Penatalaksanaan diet pasien diabetes melitus dilakukan melalui serangkaian proses asuhan gizi dan intervensi menganut prinsip 3J (Jenis, Jumlah, Jadwal). Penatalaksanaan diet diharapkan dapat membantu proses penyembuhan penyakit pasien dan mencegah komplikasi. 3 pasien menderita penyakit Diabetes mellitus dengan komplikasi stroke mengalami masalah gizi asupan makanan peroral kurang dari kebutuhan dan kurang pengetahuan selama rawat inap dengan diagnosis DM type 2 dan stroke. Pemberian diet Rendah Karbohidrat , Rendah lemak serta Rendah garam dalam bentuk bervariasi baik jenis maupun bentuk makanannya sesuai dengan kemampuan dan daya terima pasien dilakukan agar terjadi peningkatan asupan. Kolaborasi dilakukan bersama dokter penanggungjawab untuk setiap tindakan yang dilakukan . Edukasi dilakukan untuk meningkatkan pemahaman keluarga dan pasien dan memberikan motivasi kepada keluarga pasien agar setelah di rawat di rumah sakit dapat mempertahankan kesehatannya. Hasil : Intervensi yang diberikan dapat memperbaiki masalah gizi pada pasien Diabetes mellitus dengan komplikasi stroke dan hipertensi
The Analysis Study of Adenotonsillectomy for Obstructive Sleep Apnea and Quality of Life: A Systematic Review Maura Widyaratri, Putri; Hermawan, Kevin Krishnadi; Satyarini, Nidyasari Citraningrum
Jurnal Health Sains Vol. 5 No. 9 (2024): Journal Health Sains
Publisher : Syntax Corporation Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46799/jhs.v5i9.1328

Abstract

The recommended therapy for children with obstructive sleep apnea syndrome (OSAS) is adenotonsillectomy. This review aims to eval__uate if adenoidectomy alone could be a viable treatment for children with OSAS, potentially reducing morbidity, mortality, and costs. The systematic review adheres to PRISMA 2020 guidelines to ensure current and comprehensive research. Publications from 2014 to 2024 were sourced from online databases, including PubMed, ScienceDirect, and SagePub, excluding reviews, previously published, and incomplete works. The search yielded 1,446 articles on PubMed, 2,514 on ScienceDirect, and 749 on SagePub. For the year 2014, the search found 913 articles on PubMed, 1,321 on ScienceDirect, and 749 on SagePub. Ultimately, eight studies met the inclusion criteria: five from PubMed, two from ScienceDirect, and one from SagePub. The review concludes that adenotonsillectomy in OSAS patients improves behavior, symptoms, and quality of life.
The Implementation of National Health Insurance Policy in Rural Health Center Mulyadi, Hendi; Darmawan, Arif Budy; Yulyani, Nani; Sutrisno, Endang; Permana, Ipik
Jurnal Health Sains Vol. 5 No. 7 (2024): Journal Health Sains
Publisher : Syntax Corporation Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46799/jhs.v5i7.1329

Abstract

Kehidupan bermasyarakat dan bernegara tidak dapat terlaksana dengan baik apabila tidak didukung dengan upaya peningkatan kesehatan bagi masyarakat berkaitan dengan upaya kesehatan masyarakat pemerintahan mempunyai kebijakan Program Jaminan Kesehatan Nasional adalah sebuah pelaksanaan program Jaminan Kesehatan Nasional. Penelitian ini bertujuan untuk mengetahui bagaimana Implementasi Kebijakan Pelayanan Jaminan Kesehatan Nasional Di Puskesmas Pedesaan. Penelitian ini termasuk jenis kualitatif dengan wawancara mendalam, observasi langsung, dan studi keperpustakaan. Studi lapangan dilakukan melalui wawancara dengan Puskesmas Desa dan Masyarakat yang mengikuti program JKN. Teknik analisis data kualitatif deskriptif. Hasil penelitian menunjukkan bahwa Implementasi Kebijakan Pelayanan Jaminan Kesehatan Nasional Di Puskesmas Pedesaan belum maksimal dan masih terdapat kekurangan yang masih perlu diperbaiki. Penataan sumber daya manusia seharusnya berjalan dengan maksimal agar program dapat terus berjalan, penggunaan sarana prasarana masih terjadi kesenjangan dalam memperoleh pelayanan di pukesmas pedesaan, dan masih terdapat masyarakat yang kurang mampu belum mendapatkan pelayanan yang baik. Puskesmas Pedesaan sebagai pelaksana program JKN diharapkan untuk lebih mengintensifkan sosialisasi mengenai pelayanan kesehatan gratis, misalnya dengan melakukan penyuluhan dan pemasangan spanduk sehingga informasi tentang program Pelayanan JKN bisa sampai ke pelosok-pelosok desa.
Stabilitas dan Pengembangan Metode Estimasi Ruxolitinib Dengan RP-HPLC Utami, Dila Wahyu; Supriyadi, Supriyadi; Iswandi, Iswandi
Jurnal Health Sains Vol. 5 No. 7 (2024): Journal Health Sains
Publisher : Syntax Corporation Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46799/jhs.v5i7.1330

Abstract

Ruxolitinib adalah obat penghambat Janus Kinase 1 dan 2 oleh Food and Drud Administration (FDA) pada tahun 2011 yang ditetapkan sebagai pengobatan mielofibrosis dengan risiko sedang hingga tinggi. Ruxolitinib memiliki ketidakstabilan terhadap cahaya yang dapat menyebabkan penurunan kadar. Tujuan dari penelitian ini adalah untuk memperoleh metode analisis yang selektif, akurat dan tepat untuk menentukan kadar dan mengetahui stabilitas ruxolitinib. Penentuan kondisi optimum RP-HPLC dari pengembangan metode analisis dengan variasi komposisi fasa gerak, laju alir, konsentrasi buffer dan pH buffer. Metode analisis baru menentukan kadar ruxolitinib secara RP-HPLC menggunakan kolom C18 Hypersil ODS, panjang gelombang 310 nm, komposisi fase gerak asetonitril: H2O: buffer sitrat (75:20:5), volume injeksi 20 μL, buffer sitrat 0,10 M dan pH 5,8. Kurva kalibrasi antara konsentrasi ruxolitinib pada kisaran 1000-1800 μg/mL, koefisien korelasi 0,9997. Akurasi 99,65%, presisi pengulangan 0,17%, presisi antar hari 0,36%, LOD 26,48 μg/ml, dan LOQ 88,26 μg/ml. Penurunan kadar ruxolitinib setelah pemberian paparan asam sebesar 82,56%, basa sebesar 88,01%, cahaya sebesar 69,06%, suhu sebesar 75,29%. Sehingga disimpulkan bahwa metode yang dihasilkan dari pengembangan metode dan validasinya memenuhi kriteria validasi, penentuan kadar ruxolitinib menunjukkan paparan asam, basa, suhu dan cahaya yang tidak stabil.
Phenomenon Sex Pre-marriage among Adolescents in the District Lembeyan Regency Magetan Utomo, Ilham Ibnu
Jurnal Health Sains Vol. 5 No. 7 (2024): Journal Health Sains
Publisher : Syntax Corporation Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46799/jhs.v5i7.1336

Abstract

This research describes phenomenon behavior sex pre - wedding among teenagers in the District Lembeyan, Regency Magetan, as well analyze the role of parents in efforts prevention. Research methods use approach qualitative with technique interviews and documentation to teenagers below​ 19-year-olds involved in the behavior, as well as parents and local KUA officers. The result show that behavior sex pre-wedding influenced by relationships No healthy and lacking supervision from parents.​ Parent​ identified as having a role important as educators, role models, supervisors, and counselors in preventing behavior sex pre-wedding. Findings This provides input For increase understanding and action preventive in the field health teenager.

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