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Jurnal Health Sains
Published by Syntax Corporation Indonesia
ISSN : 27236927     EISSN : 27234339     DOI : http://doi.org/10.36418
Core Subject : Health,
Dentistry Health Professions Medicine & Pharmacology Nursing Public Health Veterinary
Jurnal Health Sains adalah jurnal yang diterbitkan sebulan sekali oleh Ridwan Institute. Jurnal Health Sains akan menerbitkan artikel ilmiah dalam lingkup ilmu kesehatan. Artikel yang diterbitkan adalah artikel dari penelitian, studi atau studi ilmiah kritis dan komprehensif tentang isu-isu penting dan terkini atau ulasan buku-buku ilmiah.
Arjuna Subject : Profesi Kesehatan - Bimbingan Kesehatan dan Transkripsi
Articles 764 Documents
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The Effect of Topical 0.1% Pomegranate Extract (Punica Granatum) on Trans Epidermal Water Loss (Tewl) and Skin Ph Levels in Patients with a History of Atopic Dermatitis Fernandes, Albert; Widayati, Retno Indar; Riyanto, Puguh
Jurnal Health Sains Vol. 5 No. 9 (2024): Journal Health Sains
Publisher : Syntax Corporation Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46799/jhs.v5i9.1353

Abstract

Repairing the skin barrier with moisturizers is one of the five main pillars of treating atopic dermatitis. Petrolatum is considered the gold standard, but its consistency is too thick and oily making it less comfortable to use. Moisturizers containing pomegranate extract (Punica granatum) can be an alternative choice that is more comfortable to use. The effectiveness of this pomegranate extract can be eval__uated using TEWL and pH examinations which are considered accurate indicators for changes in skin barrier conditions. Effectiveness of topical administration of 0.1% pomegranate extract in reducing TEWL and skin pH in sufferers with a history of AD.Single blind randomized clinical trial with two parallel group pre and post design. 34 sufferers with a history of AD were randomly divided into treatment groups (topical 0.1% pomegranate extract, 17 subjects) and control group (topical 100% petrolatum, 17 subjects). Moisturizer was applied twice daily to the volar area of ​​the forearm for 4 weeks. Both groups showed a significant decrease in TEWL after 4 weeks with a TEWL delta of -5.2±2.31g/m2/hour (p<0.001) in the pomegranate extract group and-7.0±7.95g/m2/hour(p=0.003) in the petrolatum group. There was no significant difference in TEWL reduction between the two study groups.The pomegranate extract group showed a significant decrease in pH after 4 weeks with a pH delta of -0.5±0.10(p<0.001), while the petrolatum group actually showed a slight increase with a pH delta of0.0±0.59 (p=0.6). The pomegranate extract group showed a significantly greater decrease in pH (p<0.001).Topical 0.1% pomegranate extract is as effective as 100% petrolatum in reducing TEWL, but more effective in lowering skin pH.
The Relationship of Smoking Status and Ventilation Extent with The Incident of Tuberculosis Nisak, Irma Dwi Khoirun; Abidin, Zaenal; Ramadanintyas, Karina Nur
Jurnal Health Sains Vol. 5 No. 9 (2024): Journal Health Sains
Publisher : Syntax Corporation Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46799/jhs.v5i9.1354

Abstract

Tuberculosis is an infectious disease caused by the bacterium Mycobacterium Tuberculosis and attacks the organs or tissues of the human body, especially the lungs, which is caused by an imbalance between the environment, agent and host. Factors that can cause the spread of tuberculosis, if treatment is not carried out quickly, will cause an increase in the number of cases of tuberculosis. The aim of this research is to analyze the relationship between family smoking status and ventilation area with the incidence of tuberculosis in the working area of ​​the Banjarejo Community Health Center, Madiun City. In this research, researchers used quantitative research as an approach. The research method used is an analytical survey while the type of research is Case Control. The total population was 35 tuberculosis cases with a sample size of 52 respondents who were divided between the case group and the control group using the Chi-Square test. The results of the study showed that there was a significant relationship between the independent variables of family smoking status (p-value = 0.018), ventilation area (p-value = 0.007) with the incidence of tuberculosis in the working area of ​​the Banjarejo Community Health Center, Madiun City.
The Effect of Topical 100% Sunflower Seed Oil (SSO) Extract on Trans Epidermal Water Loss (Tewl) and Skin PH Levels in a History of Atopic Dermatitis Megawati, Yunitasari; Widayati, Retno Indar; Malik, Diah Adriani
Jurnal Health Sains Vol. 5 No. 9 (2024): Journal Health Sains
Publisher : Syntax Corporation Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46799/jhs.v5i9.1357

Abstract

The skin barrier function can be disturbed in various conditions, one of which is atopic dermatitis (AD). Efforts to improve the skin barrier can be done by using various types of moisturizers. Natural oil from sunflower seed oil (SSO) can be used as "skin barrier therapy" by reducing trans epidermal water loss (TEWL) and skin pH levels. A randomized single blind clinical trial with a two parallel group pre and post design was conducted on subjects with a history of AD who were treated at the Skin and Venereology Polyclinic at Sunan Kalijaga Hospital, Demak. Samples were randomized into 2 groups to receive 100% SSO or petrolatum as a control. TEWL and pH assessments were carried out at the beginning of the study and at week 4. Bathing habits and complaints about using moisturizers were also assessed. TEWL values ​​decreased in the SSO and petrolatum groups (-5.8±1.93 vs -6.1±9.08, p = 0.9). The pH value in AD patients also decreased after administration of SSO extract and petrolatum (-0.4±0.10 vs -0.2±0.75, p = 0.2). The decrease in TEWL and pH in both groups was not statistically significant. This may be related to differences in bathing habits and moisturizer use in the two groups. Most of the samples in the SSO group stated that they had no complaints regarding usage. The entire sample completed the study without any reports of allergic reactions or hypersensitivity. Administration of SSO extract was effective in reducing TEWL and pH in DA with the majority of samples stating that they had no complaints about use.
Comparison of Secretome Dental Pulp Stem Cell And Mebo Ointment on The Amount of Fibroblast and Collagen In Superficial Dermal Burns Loviana Hasibuan, Soya; Fibrini, Dewi; Tjipta, Arya; Ruspita, Intan
Jurnal Health Sains Vol. 5 No. 9 (2024): Journal Health Sains
Publisher : Syntax Corporation Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46799/jhs.v5i9.1368

Abstract

Secretome Dental Pulp Stem Cells have been proposed as a new alternative for wound burn. The aim of this study is to compare Secretome Dental Pulp Stem Cells and MEBO ointment against several fibroblasts and collagen in the healing process of superficial dermal burns. This study used a post-test only controlled group design by using 15 rats that were given superficial dermal burned wounds. Rats were divided into a negative control group of NaCl 0.9% (K1), a treatment group of MEBO (K2), and a treatment group of DPSCs-secretome (K3). Histopathology was done on the 5th, 14th, and 21st days post-induction wound burn. Network-prepared histopathology by colouring Messon Trichomes. Then, it was observed under a microscope with 200x magnification. Scoring in a way semi-qualitative for assessing fibroblasts and collagen. The total score of fibroblasts in the MEBO group was higher than the DPSCs-secretome group on day 5th. In comparison, the score for increasing the amount of collagen in the DPSCs-secretome group on days 5th and 14th was higher than the MEBO group. DPSCs-secretome has better effectiveness in increasing the amount of collagen but not better in increasing fibroblasts compared to MEBO.
The Relationship Between Glycemic Control And Lipid Profile In Patients With Type 2 Diabetes Mellitus In Bangli Hospital Agustia Pradnyani, Made Ayu; Sutarjana, I Ketut
Jurnal Health Sains Vol. 5 No. 9 (2024): Journal Health Sains
Publisher : Syntax Corporation Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46799/jhs.v5i9.1371

Abstract

Type 2 diabetes mellitus (DM) is prone to diabetic dyslipidemia which is one of the factors in increasing the risk of cardiovascular disease complications. The purpose of this study was to determine the relationship between glycemic control and lipid profile in patients with type 2 DM. Research with a cross-sectional study was conducted at the Internal Medicine Polyclinic of Bangli Hospital in the period January 2023-December 2023 and as many as 60 patients with type 2 DM who met the inclusion criteria. Patients were grouped into type 2 DM patients with controlled glycemic control (HbA1c <7%) and uncontrolled (HbA1c ≥7%). Lower levels of total cholesterol (160,444 ± 30,608 mg/dl vs 203,476 ± 45,471 mg/dl; p = 0.001), triglycerides (125,500 ± 56,019 vs 202,047 ± 91,568; p = 0.002), low-density lipoprotein (K-LDL) (93,072 ± 28,443 vs 131,571 ± 44,590; p = 0.001) in type 2 DM patients with controlled glycemic control. High-density lipoprotein (K-HDL) levels (50,022 ± 14,050 vs 41,152 ± 12,619; p = 0.019) were higher in type 2 DM patients with controlled glycemic control. Statistical tests showed a positive correlation between total cholesterol (r = 0.277; p = 0.032), triglyceride (r = 0.386; p = 0.002) and K-LDL (r = 0.357; p = 0.005) levels with HbA1c levels. There was a negative correlation between K-HDL (r=-0.366; p=0.004) and HbA1c levels. The significant correlation between HbA1c and lipid profile shows the importance of glycemic control in type 2 DM patients. This can be explained in the pathogenesis of type 2 DM during the advanced phase. There was a positive correlation between glycemic control (HbA1c) with total cholesterol, triglycerides and K-LDL. There is a negative correlation between glycemic control (HbA1c) and K-HDL.
Optimizing Brain-Computer Interfaces for Methampetamine Use Disorder through Quantitative Electroencephalography (QEEG) and Transcranial Doppler Analysis: Article Review Caroline, Maria; Syahrul, Syahrul; Tugasworo, Dodik; Retnaningsih, Retnaningsih; Juswanto, Gerard
Jurnal Health Sains Vol. 5 No. 9 (2024): Journal Health Sains
Publisher : Syntax Corporation Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46799/jhs.v5i9.1372

Abstract

A Brain-Computer Interface (BCI) is a system that allows a person to control external devices using only their brain activity. It works by translating brain signals into commands that can be understood by a computer. Several lines of evidence demonstrated the deleterious effect of methamphetamine (MA) on neurological and psychological functions. The use of amphetamines, such as MA, is associated with cerebrovascular complications such as cerebrovascular accidents (CVA) ,hemorrhage, hypoxic damage and vasculitis. Interestingly, while changes to cerebral blood flow (CBF) in response to acute amphetamine exposure have been reported. Transcranial Color Doppler (TCCD) is a non-invasive medical imaging technique that uses ultrasound waves to measure blood flow velocity in the major arteries of the brain, specifically within the circle of Willis. The research paper you referenced explores the use of TCCD as a potential measurement modality for BCIs. Quantitative electroencephalogram (qEEG) is a powerful tool for understanding brain function qEEG can reveal specific brain wave patterns associated with drug addiction, potentially providing insights into the neurobiological mechanisms underlying cravings, withdrawal symptoms, and relapse risk in Methamphetamine User Disorder (MUD). There is growing research interest in using Transcranial dopller as a measurement modality for BCIs.Here are some of the key considerations for using Transcranial doppler in BCIs: Mental Tasks, signal processing and classification, accuracy and reliability. Transcranial doppler provides information about blood flow in specific arteries but lacks detailed spatial information about brain activity. These patterns could vary depending on the type of drug, the severity of addiction, and individual differences. Transcranial doppler in measuring middle cerebral artery (MCA) blood flow velocity parameters (peak systolic velocity (PSV) and mean flow velocity (MFV)). qEEG can help researchers investigate the complex interplay between addiction and other brain disorders, like depression or anxiety. Characteristic qEEG in drugs addiction Increased Theta (4-8 Hz) and delta (1-4 Hz) brain waves are often associated with sleep and relaxation. However, research has shown that individuals with drug addiction may have increased theta and delta activity, particularly in the frontal and temporal regions of the brain. Altered Beta (13-30 Hz) brain waves are generally associated with wakefulness, alertness, and cognitive processing. Studies have observed both increases and decreases in beta activity in individuals with drug addiction, depending on the type of drug, the stage of addiction, and the specific brain regions being examined. The results of this research have important practical implications for building an diagnostic and functional assement with a better understanding of an using technology.
Dental Health Care Model In Premature Contact Patients With Partial And Complete Removable Denture Installation At Rsgm Semarang Muhammadiyah University Furqan, Muhammad; Santoso, Bedjo; Fatmasari, Diyah; Agung Bakhtiar, Dika; Sutomo, Bambang
Jurnal Health Sains Vol. 5 No. 9 (2024): Journal Health Sains
Publisher : Syntax Corporation Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46799/jhs.v5i9.1373

Abstract

Prosthodontic specialist dentistry services are services for the patient's rehabilitative needs with the aim of restoring the function of the oral cavity such as teeth and mucosa by paying attention to the comfort and anxiety of the patient during treatment. The complaints that often occur in premature contact patients with partial and complete denture installation are discomfort, pain, anxiety, and bad breath. There is no government policy in providing guidelines for dental and oral health care for patients specifically for prosthodontics. The preparation of a dental and oral health care model for premature contact patients with partial and complete dentures in hospitals. The design of this study uses Research and Development (R&D) with the Quasi experimental method with a pretest posttest control group design. The number of respondents was 10 dental and oral therapists, and 20 patients who used removable dentures with premature contact. Dental and oral therapist respondents were given a pretest, training, followed by a skill assessment by providing care services to patients, and ended with a posttest. Patients were given a pretest and posttest. The instrument of this research is a questionnaire that has been carried out validity and reliability. Le test de validation expert du modèle de soins dentaires et bucco-dentaires a obtenu des résultats décents avec une valeur p = 0.003 et son application a été efficace pour accroître les connaissances des thérapeutes dentaires et buccaux (p = 0,013), ameliorate l'attitude des thérapeutes dentaires et buccaux (p = 0.043), ameliorate les compétences des thérapeutes dentaires et buccaux (p = 0.01), réduire l'anxiété des patients (p = 0.001) et augmenter l'observance des patients (p = 0.001) Modèle de soins dentaires et bucco-dentaires pour les patients ayant un contact dentaire prématuré Les polyprothèses prothétiques amovibles sont efficaces pour améliorer les connaissances, l'attitude et les compétences des thérapeutes dentaires et buccaux, ainsi que pour réduire l'anxiété et améliorer l'observance du patient.
How Safety Knowledge and Work Environment Affect Workplace Accidents: Uncovering the Role of Safety Behaviors Marcia, Marcia; Kusumapradja, Rokiah; Silviana Mustikawati, Intan
Jurnal Health Sains Vol. 5 No. 9 (2024): Journal Health Sains
Publisher : Syntax Corporation Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46799/jhs.v5i9.1378

Abstract

Workplace accidents in hospitals can arise from human or environmental factors, highlighting the necessity of implementing Hospital Occupational Safety and Health (HOSH) measures. Preliminary study at X Hospital shows that work-related accidents persist, with the majority leading to physical injuries. This study aims to observe the impact of HOSH knowledge and the work environment on nurse workplace accidents, with safety behaviors serving as a mediating factor. The research utilizes a quantitative survey method with a cross-sectional design. A total of 123 nurses participated in the study. An analysis using Structural Equation Modeling (SEM) was conducted to assess the statistical impact. The findings indicate that improving Occupational Safety and Health (OSH) knowledge and enhancing the work environment can significantly reduce workplace accidents. The mediating role of safety behaviors further amplifies this effect. Both HOSH knowledge and the work environment have a positive significant impact on safety behaviors, while HOSH knowledge, the work environment, and safety behaviors each have a negative significant impact on workplace accidents
Effect of Ashitaba Extract on Cholesterol in Wistar Rats Given a High-Fat Diet and Computational Lethal Dose Test Widyaningsih, Indah; Nurulita Sugiharto, Natasya; Rahmawati, Febtarini; Amma, Fuad; Simamora, Dorta
Jurnal Health Sains Vol. 5 No. 10 (2024): Jurnal Health Sains
Publisher : Syntax Corporation Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46799/jhs.v5i10.1365

Abstract

High cholesterol levels in the blood can cause various health problems, namely atherosclerosis, stroke, coronary heart disease, and hypertension. One drug option for someone with hypercholesterolemia is simvastatin. Apart from using simvastatin, you can consume medicinal plants. A medicinal plant that can help reduce high cholesterol levels is Ashitaba (Angelica keiskei) leaf extract. One of the ingredients in Ashitaba extract is xanthoangelol E, Ashitaba chalcones, which can reduce cholesterol synthesis. The aim of this research was to determine the effect of ashitaba (Angelica keiskei) extract on the cholesterol levels of Wistar rats (Rattus novergiccus) given a high-fat diet. In this study, a computational lethal dose test was also carried out. The population in this study was male white rats of the Wistar strain with 30 samples taken. Analysis of this research data uses the One Way Anova statistical test. The results of the study showed that giving ashitaba extract 150mg/kg BW, 300mg/kg BW, and 600mg/kg BW had no effect on the cholesterol levels of Wistar rats given a high-fat diet. This is proven by the results of the Anova test which obtained a significance value of 0.761 > 0.05. Research regarding the toxic effects of ashitaba extract needs to be carried out for further research.
Evaluation Of Polypharmacy And Excessive Polypharmacy In Geriatric Inpatients In General Hospital Surya Lita, Erlinda; Paulina Sormin, Ida
Jurnal Health Sains Vol. 5 No. 10 (2024): Jurnal Health Sains
Publisher : Syntax Corporation Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46799/jhs.v5i10.1375

Abstract

Polypharmacy is the simultaneous use of drugs with 5-9 drugs. Excessive polypharmacy is the simultaneous use of drugs with ≥ 10 drugs. Chronic diseases that are commonly suffered by geriatric patients are prone to causing a person to receive polypharmacy or excessive polypharmacy. This study aims to eval_uate polypharmacy and excessive polypharmacy in inpatient geriatric patients, by knowing the factors that may trigger a person to receive polypharmacy. The research uses a cross-sectional study method, using medical record data for the period January to December 2023. The part studied was in the form of sociodemographics, disease history and treatment of patients, as well as length of stay. From the research conducted, the results were obtained from 295 patient data samples with 141 patients (47.8%) and 154 patients (52.5%) were female. The age of patients consisted of 60-74 years old 192 patients (65.1%), 75-90 years old 100 patients (33.9%), and ≥ 90 years 3 patients (1%). The last education of the highest patient with a high school background was 101 patients (34.2%), the highest marital status was married as many as 245 patients (83.1%). The diagnosis of the third disease has the most patients, namely diabetes mellitus as many as 95 patients (15.5%), anemia as many as 70 patients (11.5%), and hypertension as many as 56 patients (9.2%). The preval_ence of polypharmacy in geriatric patients was 115 patients (39%) and excessive polypharmacy was 180 patients (61%). Broadly speaking, the sociodemographics of patients do not have a relationship with the occurrence of polypharmacy and excessive polypharmacy. The patient's clinical condition has a relationship with the occurrence of polypharmacy and excessive polypharmacy, this is evidenced by a p value of 0.000 (<0.05). The length of hospitalization and diagnosis of the patient's disease is a predictor of polypharmacy and excessive polypharmacy.

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