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INDONESIA
Indian Journal of Forensic Medicine & Toxicology
Published by Official Organ of Indian Association of Medico-Legal Expert
ISSN : -     EISSN : -     DOI : -
Core Subject : Health,
Public Health
Arjuna Subject : Kedokteran - Epidemilogi
Articles 5,497 Documents
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Development and Validation of UV-Spectrophotometric Method for Quantitative Assessment of Metronidazole in the «Metromed® Neo» Solution for Infusion Khilola Ganieva1, Akhmad Yunuskhodjaev2
Indian Journal of Forensic Medicine & Toxicology Vol. 14 No. 4 (2020): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v14i4.12801

Abstract

Introduction: Metronidazole is widely used in medicine and issues of quality control of its dosage formsare relevant. Objective - development and validation of a UV spectrophotometric method for monitoring thequality of metronidazole in the «Metromed® Neo» solution for infusion.Materials and Method: The object of the study was a solution for infusion containing metronidazole. Themethod used is UV spectrophotometry.Results: The relative error of the developed UV spectrophotometric method for the quantitative assessmentof metronidazole in the solution for infusion was 1.9%. Validation characteristics of the method are withinacceptable limits.Conclusion: A UV spectrophotometric technique was developed and validated to assess the quality ofthe solution for infusion containing metronidazole. The results of the studies make it possible to use thedeveloped and validated methodology in assessing the quality of metronidazole.
Features of Manifestation of Optokinetic Nystagmus in Meniere’S Disease Makhzuna Tahsinovna Nasretdinova1, Ozod Rakhmatullaevich Nabiev1
Indian Journal of Forensic Medicine & Toxicology Vol. 14 No. 4 (2020): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v14i4.12802

Abstract

The characteristics of optokinetic nystagmus (O?N) were studied in 20 healthy individuals and 30 individualssuffering from Meniere’s disease in remission. The results recorded by the method of electronystagmographyat frequency optokinetic stimulation 66,90 156 and field/min. found that in healthy people, the frequencyof IPOs, the total amplitude and the speed of the slow phase(sp) nystagmus increases proportional to theincrease in the frequency optokinetic stimulation; accordingly, consistently reduced the average amplitudewindow. In Meniere’s disease, O?N indicators are generally characterized by lower values than normal,and an increase in the frequency of optokinetic stimulation is accompanied not only by a more pronounceddecrease in the total amplitude indicators, but also by a decrease in the speed of the slow phase of O?N.After the glycerol load and with positive results of the glycerol test, the quantitative indicators of O?Nincrease in patients, approaching the physiological norm. It is concluded that it is appropriate to study theO?N in Meniere’s disease to clarify the stage of the disease and predict the effectiveness of treatment.
Some Features of the Bacteria of the Family Enterobacteriaceae Allocated from Small Cattle at Different Pathological Processes Ruslan Gayrabekov1, Raisa Gayrabekova1, Luiza Molochaeva1
Indian Journal of Forensic Medicine & Toxicology Vol. 14 No. 4 (2020): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v14i4.12803

Abstract

Enterobacteria with a certain set of pathogenicity factors and capable of leading to the development of diseasesof animals and humans are ubiquitous in nature, which can be recognized as the result of anthropogenicactivity. Recently, they have been isolated with increasing frequency from soil, water, from fruits,vegetables, grains, plants, from representatives of various systematic groups of animals and humans. Wehave obtained bacteria from sheep with gastrointestinal pathologies. From sick animals, we have identified alarge number of bacterial cultures belonging to species of different genera of the Enterobacteriaceae family.Among them, 190 cultures, species belonging to Escherichia coli, 124 cultures of Enterobacter cloacae,74 cultures of Morganella morganii, 51 culture of Citrobacter freundii, 29 cultures of Serratia marcescens.For these microorganisms a large set of various pathogenicity factors was characteristic: antilysocyme,anti-complementary, anti-interferon activity, adhesive ability, hemolytic activity, multiple resistance toantibacterial drugs.The aim of our work is to study the spread of enterobacteriosis, some features of the epizootic process inthese diseases in the territory of the Chechen Republic
The Communicative Skills Correction Technology of Children with Autistic Spectrum Disorder in the Crimea Svetlana Motornaya1, Margarita Belenkova1
Indian Journal of Forensic Medicine & Toxicology Vol. 14 No. 4 (2020): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v14i4.12804

Abstract

The communicative skills correction technology in children with autism spectrum disorder is considered. Inthe Crimea centers and funds which provide support and assistance to families raising children with specialdevelopmental features, in particular autism, are being analyzed. The results of a communicative skillscorrection study in children with autism spectrum disorder are presented.
Indices Changes of Central Hemodynamics at Carry Out Anesthesia with Keeping Independent Breathing at Children Gulchekhra Ashurova1, Nigora Zokirova2, Talat Agzamkhodjayev3, Anvar Yusupov4, Ikhtiyor Mamatqulov5
Indian Journal of Forensic Medicine & Toxicology Vol. 14 No. 4 (2020): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v14i4.12805

Abstract

Introduction: The aim of study was to research hemodynamic shifts in conditions of carry out combinedanesthesia on the base of isoflurane with preservation of spontaneous breathing at small surgical operationsin children.Materials and Method: The research was carried out at 44 sick children at the age from 3 to 14 years withinguinal and inguinal hernias (41,7 %), hydrocele was (19,4 %) section of abscesses and suppurations were(38,9%). The duration of anesthesia benefit at 58,3 % patients was from 30 to 40 minutes, at 40,66 % it wasabout 60 minutes.Results: The clinical monitoring was performed with study AP, HR and oxygen. For objective evaluationof cardiovascular functional condition, the echocardiography way was use. The first group patients wereintroduced intravenously the ketamine solution in doze 3 mgr/kg of body weight, propofole in dose 2 mgr/kg of body weight and izoflurane up to 3 ob % in 30-40 minutes after premedication. The second grouppatients were introduced intravenously the ketamine solution in dose 4-5 mgr/body weight and sibazone indose 0,4 mgr/kg.Conclusion: Complex clinical study and taken results of hemodynamic parameters showed the efficiency ofcarried out anesthesia with safety of independent breathing at small surgical operations at children.
Current View of the Problem: A New Approach to Covid-19 Treatment Jasur A. Rizaev1, Ezozbek A. Rizaev2, N.N. Akhmadaliev3
Indian Journal of Forensic Medicine & Toxicology Vol. 14 No. 4 (2020): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v14i4.12806

Abstract

Coronavirus infection COVID-19 (acronym for Corona Virus Disease 2019), formerly Coronavirus infection2019-nCoV is a potentially severe acute respiratory infection caused by SARS-CoV-2. It is a dangerousdisease that can take the form of an acute respiratory viral infection of the lung or a severe form, the specificcomplications of which may include viral pneumonia leading to acute respiratory distress syndrome orrespiratory failure with a risk of death.
Morphological Characteristics of Intestinal Vessels of Animals with an Experimental Model of Diabetes Mellitus Type 2 Complicated by Microangiopathy Alisher Okhunov1, Rajabbay Israilov1, Shukhrat Razzakov1, Pakiza Azizova1, Alisher Mominov1
Indian Journal of Forensic Medicine & Toxicology Vol. 14 No. 4 (2020): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v14i4.12807

Abstract

Diabetes mellitus and its complications are considered far from unresolved problems of modern medicine.An important aspect in solving fundamental problems is experimental research aimed at assessing the stateof change of pathogenetic important key positions in the development of such a formidable complicationof diabetes as angiopathy. On the other hand, surgeons’ great interest in bariatric and metabolic surgery,as method of surgical treatment of type 2 diabetes mellitus, requires in-depth studies to assess the stateof angiogenic changes in the organs of the gastrointestinal tract, namely in the intestine. The articledescribes the morphological changes in the vascular capillary bed in the dynamics of the development ofa new experimental model of diabetes mellitus, namely the chemical method of diabetic angiopathy. Thedevelopment of an experimental model of diabetic angiopathy showed the staged nature of the changes inthe form of the initial signs of angiopathy, with perivascular infiltration and edema in the form of congestiveplethora in the flesh until the development of vascular hyalinosis, which indicates the irreversibility of theprocesses of pathological transformation. Thus, the results of morphological studies in the dynamics ofmodeling of diabetic angiopathy indicate the development of diabetes mellitus with its complication in theform of microangiopathy.
Clinical and Biological Importance of Micro RNA in the Formation of Women Reproductive Losses Kamola A. Sattarova1, Farida M. Ayupova2, Dilnoza D. Saidjalalova3, Dildora A. Ayupova4, Irina S. Ak
Indian Journal of Forensic Medicine & Toxicology Vol. 14 No. 4 (2020): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v14i4.12808

Abstract

Habitual miscarriage is currently one of the most frequent complications of the gestational process, whichis diagnosed in 10-25% of pregnant women. (IuA, 2017) Habitual abortion (miscarriage) - spontaneousinterruption of pregnancy two or more times in a row.So, high expression of miR133a may mediate a decrease in HLA-G expression at the protein level andmay be implicated in the pathogenesis of habitual miscarriage, since HLA-G provides immune tolerance inpregnancy49. So, the literature data suggest that microRNA dysregulation may be related to the pathogenesisof various obstetric complications, but accurate methodological approaches to the diagnosis and predictionof pregnancy complications using microRNA require further study.
The Value of Neurospecific Protein S-100 and Lipoproteins in the Development of Multiple Sclerosis Markhamat M. Yakubova1, Mukaddas A. Mukhiddinova2
Indian Journal of Forensic Medicine & Toxicology Vol. 14 No. 4 (2020): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v14i4.12809

Abstract

This article describes the clinical picture of multiple sclerosis (MS) depending on indices of the neurospecificprotein s-100? and low-density lipoproteins. In patients with MS in the phase of activity, high levels ofs-100? protein and LDL were found. It means that in patients with MS, demyelination and degenerationprocess continues, and as a result, patients are more likely to develop new symptoms. Thus, the study resultsof s-100? protein and LDL can be used to predict possible development of adverse symptoms in multiplesclerosis.
Epidemic Process of Salmonellosis in Tashkent Nargiza S. Saidkasimova1, Omon M. Mirtazaev2
Indian Journal of Forensic Medicine & Toxicology Vol. 14 No. 4 (2020): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v14i4.12810

Abstract

In the latest decade, epidemiological features of salmonellosis morbidity have changed, in particular, thefraction of humans and animals, caused by S. enteritidis, has increased. It was caused by social changesin the population life: widespread development of private property, increased population migration, rapiddevelopment of the public catering system, etc. The features of salmonellosis epidemic process wereanalysed in Tashkent. S. enteritidis has also dominated in the causal structure of salmonellosis, registered infood products and other environmental objects over the past twenty years in Tashkent.In the long-term dynamics of salmonellosis morbidity in Tashkent, there is a downward trend: in 1991 -92.85 cases per 100 thousand people, in 2017 - 13.2, that is, over a 26-year period, the morbidity decreasedby 6.7 times.

Page 237 of 550 | Total Record : 5497

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