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INDONESIA
Indian Journal of Forensic Medicine & Toxicology
Published by Official Organ of Indian Association of Medico-Legal Expert
ISSN : -     EISSN : -     DOI : -
Core Subject : Health,
Public Health
Arjuna Subject : Kedokteran - Epidemilogi
Articles 5,497 Documents
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Peritoneal Tuberculosis as a Final Result of Diagnostic Conundrum: A Case Report Ananda Febriani Aulia1 , Azizman Saad2 , Zarfiardy Aksa Fauzi2 , Ari Hidayat3 , Yenni Oktavia4 , Wiw
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 1 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i1.13519

Abstract

Peritoneal tuberculosis is a disease which can mimic malignancy especially in women present with ascites andelevated CA125 levels. It always should be considered in the differential diagnosis. Peritoneal tuberculosiswith ambiguous patient symptoms and diagnostic difficulties still poses a great challenge in clinical practice.A 33 years old woman was admitted to hospital with complaints of abdominal pain and shortness of breath.Initially, elevated serum antigen CA-125, ascites, pleural effusion, and multiple suspicious nodules in thelungs and abdominal cavity on CT were found, thus, diagnosing advance stage ovarian cancer. Biopsylaparotomy was performed, and post-operative histological examination was peritoneal tuberculosis. Thepatient was treated with first-line antituberculosis agents and discharged home. Almost in all other cases,peritoneal tuberculosis is diagnosed only after surgical intervention.
The Relation between Exercise Duration and Intensity on Phosphocreatine (PCr) Level: an Article Review Aprilia Durotun Nasikhah1 , Roy Januardi Irawan2 , Trias Mahmudiono3*
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 1 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i1.13520

Abstract

Exercise is a physical activity that planned, structured, and sustainable. Exercise has 4 criteria, that isfrequency, intensity, type, and duration. During exercise, phosphocreatine (PCr) depletion increases, andearly intracellular acidosis has occurred. These changes contribute to a decrease in training capacity interms of training duration. This literature review aimed to determine the relationship between the intensityand duration of exercise with the concentration of PCr and recovery factors. The literature study has carriedout by selecting an Experiment research design. The results of the review showed that PCr was the largestenergy contributor in the first 10 seconds of exercise in the heavy-intensity exercise where phosphocreatinetriggers energy without oxygen or anaerobic. The recovery of PCr influenced by a person’s health conditionand age. The concentration of PCr in children was higher than in adults because of the relatively high rateof oxidative ATP formation. It proved that there was a significant relationship between PCr and the durationand intensity of exercise.
The Effect of Mixed Liquor Administration on The Johnsen’s Score and The Number of Sertoli Cells and Leydig Cells on The Wistar Strain White Rats (Rattus norvegicus) Aqidah Khariri1 , Anny Setijo Rahaju2,4, Arifa Mustika3
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 1 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i1.13521

Abstract

To analyze the effect of mixed liquor administration on the Johnsen’s score and the number of Sertoli cellsand Leydig cells on the Wistar strain white rats (Rattus norvegicus). A total of 28 rats were divided into 4groups: C, P1, P2, and P3. Rats were given mixed liquor with different dose, namely P1 (1 ml), P2 (2 ml),and P3 (4 ml) each day for 14 days, then compared to C group which was given 4 ml of distilled water usingan oral gavage. Mixed liquor consists of 20% ethanol and 4% methanol. The histopathological features wereevaluated by the Johnsen’s score, the number of Sertoli cells, and Leydig cells in cross-sectional preparationof rat testicular tissue with 400× magnification. Datas were analyzed using the Kruskal-Wallis test and OneWay ANOVA test with a confidence level of p <0.05. The P3 group had the lowest Johnsen’s score and thenumber of Sertoli cells, 6.442±0.293 and 5.942±0.674, respectively. A significant decrease in increased doseoccurred in the Sertoli cell count but not in the Johnsen’s score. Group P2 had the lowest number of Leydigcells, 6.421±0.360. The administration of mixed liquor caused a decrease in Johnsen’s score and the numberof Sertoli cells and Leydig cells on the Wistar strain white rat (Rattus norvegicus).
Biological Activity Investigation of Phytocomponents in Mangosteen (Garcinia mangostana L.): In Silico Study Arif Nur Muhammad Ansori1 , Raden Joko Kuncoroningrat Susilo2 , Suhailah Hayaza2
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 1 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i1.13522

Abstract

Indonesia has abundant medicinal plants, which have been historically used by the population in treatingdiseases for generations. Traditional Indonesian medicine and the medicinal plants used could lead to thediscovery of novel drugs. The mangosteen or Garcinia mangostana L. is a well-known medicinal plantthat has been used to treat various diseases worldwide. The pharmacological activities and phytochemicalcomposition of the whole plant of mangosteen have been investigated and identified by scientists in recentdecades. Therefore, this study aims to generate the prediction of the biological activity of phytocompotentsin mangosteen. In this study, we extracted 18 phyocomponents of mangosteen from PubChem, an openchemistry database at the National Institutes of Health (NIH), USA. Then, we predicted the pharmacokineticproperties and druglike nature of the phytocomponents using the SwissADME web server, Swiss Instituteof Bioinformatics, Swiss. Furthermore, PASS (Prediction of Activity Spectra for Substances) web resourcehas been employed as a strong potential tool to predict the biological activity. In summary, we revealed thebiological activity of 18 phytocomponents of the mangosteen. However, further trials, such as in vitro andin vivo evaluation, are needed to prove the validity of these findings.
A Mini-Review of the Medicinal Properties of Okra (Abelmoschus esculentus L.) and Potential Benefit against SARS-CoV-2 Arif Nur Muhammad Ansori
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 1 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i1.13523

Abstract

Indonesia is rich in medicinal plants, where its population has traditionally used them for generations tocure diseases. Traditional medicine and medicinal plants from Indonesia may lead to the discovery of noveldrugs. Abelmoschus esculentus L. or okra is well known as a cure for several diseases and is includedin various folk medicinal stockpiles. In recent decades, scientists have discovered the phytochemicalcomposition in the whole okra plant, as well as its pharmacological activities. These studies establishedthe therapeutic potential of okra for drug discovery. Therefore, the present review provides a sneak peek ofokra’s pharmacology and phytochemistry, also the potential benefit against SARS-CoV-2.
Identify Population Attitude Towards Osteoporosis and Pharmacists Involvement in Community Education in Makkah, Saudi Arabia: A Cross-Sectional Study Arwa Fairaq1 , Byader Sulimani2 , Ghada AlAhmadi2 , Nouf Adnan Hijii2 , Rahma AlEssa2 , Sara AlHarth
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 1 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i1.13524

Abstract

Introduction: Fracture is the most severe clinical consequence of osteoporosis. Unfortunately, most patientsare unaware that they have fragile bones until they fracture the hip, spine, pelvis, or wrist. Thus, increasedisability, hospitalization, and so on total health care costs. In Saudi Arabia, many middle-aged and olderwomen were unaware of osteoporosis risk factors with a high prevalence of osteoporosis reported in SaudiArabia.Aim: This study’s main objective is to evaluate population awareness about osteoporosis and pharmacist’sinvolvement in patient education to minimize the risk of osteoporosis in the Makkah region.Methods: A cross-sectional study was performed using an online survey. A total of 1390 participantscompleted the questionnaire from 15 February to 15 Marc 2019.Results: only 1.4% of participants had a risk for osteoporosis and got the advice from pharmacists.Significantly, 53.7% had a chance but didn’t get any advice from either physicians or pharmacists.Conclusion: The results show a low self-awareness level in Makkah’s general population with insufficientinvolvement of pharmacists in patient education.
The Possible Relation between Pityriasis Alba and Intestinal Parasitic Infestation Among Children in Tikrit City, A Case Control Study Asaf Kamal Asaad Taha1 , Mazin Hamid Ayyash2
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 1 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i1.13525

Abstract

Background: There is a solid belief stated that the appearance of hypopigmented patches on childrenface is a sign of their helminthic or parasitic intestinal infestation despite the constant health educationabout the absence of such relation. Pityriasis Alba (PA) is common benign skin lesion characterized byfine scaly hypopigmented patches (HP) or macules (1) mostly in the face and upper body parts. (2-4) PAmay be atopic dermatitis related or endemic PA. PA occurs mostly in 3-16 years old children and accountsof 5% of pediatric population worldwide. Prevalence rate in Iraq is high (38.2%). No specific cause ofPA has been identified. Diagnosis of PA depends on the clinical picture and treatment may implicatesunscreen and topical corticosteroids despite its self-limiting privilege. Helminthiasis (worm infestation)is the hosting of parasitic worms after invading humans and other animals necessarily to complete theirlifecycle. Enterobius vermicularis is the most common helminthic intestinal infestation among children inIraq. The main complaint of helminthiasis is the perianal itching, especially at bed time. The study aims todetermine the relation of intestinal helminths with PA. Study Design: This prospective and a case-controlstudy had consisted of 43 males (53.5%) and females (46.5%) children of 5-15 years of age presented withHP. Results and Discussion: 4 (9.3%) cases presented with Enterobius vermicularis given antihelminthicdrugs and had their infestation eradicated completely after a week. 39 (90.7%) children presented with noinfestation, regarded as control group, and so given placebo treatment. Number and size of HP varied afterthe 6 weeks of treatment. Although cases shown more numerous (6.0 ± 2.9) HP and larger size (120.0 ± 72.2)than control group (4.9 ± 3.6 and 90.0 ± 58.3 respectively), but the difference was not significant for bothgroups (cases and control) and between them for both HP number and sizes (p>0.6). Conclusion: There isno enough prove of the relationship between children intestinal parasitic infestation and the appearance ofhypopigmented patches.
Investigate the therapeutic effect of autologous adipose-derived stem cells (ADSCs) on ischemic renal failure in dogs. Bassim K .Khashjoori1 , M. S. Ghaji1 , Omar Tariq Hammoodi2 , Majid A. Alkhilani2 , Ali. A. Ajeel 3
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 1 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i1.13526

Abstract

Background/ aim: The kidney excretes waste materials and regulates important metabolic functions, andrenal disorders constitute a significant medical problem and can result in fatalities. In the present study,mesenchymal stem cells derived from canine adipose tissue were isolated and evaluated for their ability toimprove renal function in a canine model of ischemic renal failure. Materials and Methods: The canineischemic renal failure model was developed by a traumatic occlusion of the renal artery in 10 dogs. ASCswere administered directly into the renal artery following ischemic renal failure induction. Blood analysisand histological parameters were analyzed. Results: The group treated with ASCs had decreased blood ureanitrogen and creatinine levels, and showed an improving histological manifestation. ASCs were detectedaround the tubules of these kidneys at the histological level. Conclusion: our findings suggest that ASCscould be an alternative therapeutic agent for canine ischemic renal failure.
Correlation of PTEN Losses by Immunohistochemistry and Fish in Prostate Adenocarcinoma Batool Jameel Jubair1 , Sazan Abdulwahab Mirza Al-Atroshi2
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 1 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i1.13527

Abstract

Background: Prostate cancer (PC) is the largest and most unusual site of robust neoplasm in Europe,accounting for 22.8% of all newly diagnosed cancers in men. An increase in the prevalence of pentachloroanisole has been observed in most countries. This may be explained by the massive use of prostate uniqueantigen (PSA) in the early detection of PCa in the early stages. Objective: Detection of PTEN loss by IHCand FISH technique and compare between the two methods and correlate with Gleason grading system.Patients and method: A retrospective sample study was performed. From January 2014 - Joe. 2019. Thisstudy included 120 cases of prostate cancer from Baghdad and Duhok, with different age groups. Fixedformalin paraffin biopsy for prostatectomy in cases obtained from the Archives of Pathology Laboratories inBaghdad” (Shahid Ghazi Hariri Training Hospital and Laboratories).Results: PTEN (FISH) detected the gene in 29 case and confirmed by PTEN (IHC) expression results,underestimation occurred in five case detected by PTEN (IHC). Concerning PTEN (IHC), it detected the genein 34 case. Percentage of cases showing negative staining for PTEN protein in high grade was higher thancases showing positive protein expression (good correlation with new grading group). IHC to detect PTENprotein levels is an interesting alternative to knowledge of the FISH PTEN gene loss and as a prognosticbiomarker. There was significant association between PTEN gene expression and age. PTEN (IHC) showednegative results in 65.3% of case; while loss was shown in 58.2% of s by PTEN (FISH).Conclusion: The important result in this study was a substantial agreement between the expression resultsof PTEN (FISH) and PTEN (IHC).
Impact of Diastasis Recti Abdominis and Low Back Pain on Quality of Life in Post-Partum Female Bhavna Gandhi1 , Shalaka Dhankar2
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 1 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i1.13528

Abstract

Introduction: The separation of the two rectus abdominis muscle along with linea alba is called diastasisrecti abdominis. Diastasis recti is comman in Post-partum females. In Post-partum period Low back Pain isvery comman which lead to daily activity limitation. Post-Partum women complaint regarding there usualactivities, mobility, pain, which affect the quality of life in individual.Aim: To study the” Impact of diastasis recti and low back pain on quality of life in post-partum females”Method: This study will be carried out in Physiotherapy OPD, Ravi Nair Physiotherapy College andAVBRH, Sawangi (Meghe), Wardha. Diastasis recti will be evaluated in Post-partum females. Impact ofDiastasis recti and Low back pain on Quality of Life in post-partum female. Low back pain is going to asseswith the help of Modified Owestry low back pain disability questionnaire .And quality of Life with the helpof Maternal postpartum questionnaireResults: Study yet to be commenced.Conclusion: Conclusion will be published after the result are analysed.

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