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Indian Journal of Forensic Medicine & Toxicology
ISSN : -     EISSN : -     DOI : -
Core Subject : Health,
Articles 5,497 Documents
Study of some immunological variables resulted from Balb/c mice injection with Hydatid cysts protoscolex antigens A. O. Humide1 , Abbdalwahab Hussain2 , Ezeddin A. Albayyar3
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 1 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i1.13725

Abstract

Human cyst disease is a common epidemic disease between humans. The current study was carried out tostudy some of immunological parameters (the immunoglobins IgG, IgA, the complement proteins C3, C4,the MIF of PMNs cells, the reducing of NBT and the phagocytosis of Candida albicans) in the Balb/c miceinjected with antigen of protoscolex. By using (15) BALb/c mice and the antibodies IgG, IgA in addition tothe complements (C3, C4) that were measured as well as the Migration Inhibition Factor (MIF). The resultsshowed that there were significant differences in IgG (13458) mg/dl. IgA (4773) mg/dl, C3 (359.7) mg/dl,C4 (90.80) mg/dl levels with injection of 0.5 ml in muscle and the MIF levels (1.49) with injection of (0.75)ml. so between the test and the control up (p?0.05). This might be a good candidate for immunization anddiagnosis of Hydatid cysts in the intermediate host of E. granulosus.
Study of the Biochemical Markers of Liver and Renal Function in Moderate -To- Heavy Cigarette Smokers’ Men in Mosul City Enaam Ahmed Hamza Al-Dagestani
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 1 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i1.13727

Abstract

Smoking has been associated with adverse health effects on body organs. The effect of smoking on theliver’s enzymes and kidney’s parameters, and their relationships with some blood parameters need moreevaluation. This study aimed to investigate the association of cigarette smoking to liver and kidney functionsin 68 males, all of them not suffer from chronic disease and their ages were between (25-45) years, byestimating the levels of alanine aminotransferase (ALT), aspartate aminotransferase (AST) and alkalinephosphatase (ALP) as liver enzymes as well as estimating of creatinine, urea, and uric acid in the serumof smokers comparing with non-smokers groups (control). Also, this work aimed to study the effects ofsmoking on some blood profiles, white blood cell counts (WBC), red blood counts (RBC), hemoglobin(HB), mean corpuscular volume (MCV), and platelet (PLT) . The results showed a significant increase in(ALT), (AST), (ALP) enzymes, urea, creatinine (WBC), (RBC), (HB) and (MCV) ,the result also showeda significant decrease in uric acid while no significant decrease in (PLT) in smokers comparing to nonsmokers’ group. In conclusion a cigarette smoking negatively affected in biochemical markers of liver andkidney function.
The Effect of Dual-Species Biofilms, Monosaccharide and D-Amino Acids on Pseudomonal Biofilm Al-Moghira Khairi Al-Qaysi1 ; Safaa Abed Latef Al-Meani2 ; Mushtak T.S. Al-Ouqaili3
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 1 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i1.13728

Abstract

Background: The major therapeutic failure in clinical settings is due to problematic biofilm-producingbacteria like Pseudomonas aeruginosa. This study aims to investigate the effect of dual-species biofilms,monosaccharide, and D-amino acids on pseudomonal biofilm. Methodology: A total of 130 patients withcatheter-associated urinary tract and wound infections were involved in this study. Quantitative biofilmassay by alginate beads was performed. The dual-species biofilms have been done, and the effect ofciprofloxacin, monosaccharides, and D-amino acids on sessile cells was detected. Conclusion: This studysuggested that the combined action of both monosaccharides (glucose and galactose) and the combination ofeach one with ciprofloxacin is the enhancing of P. aeruginosa biofilm and increases survival strategy againstciprofloxacin. In contrast, a noticeable biofilm reduction and marked synergistic action for ciprofloxacinhave been determined in the combination of the two D-amino acid, alanine, and glycine in comparison tothe effect of each one alone. Furthermore, the dual biofilm of P. aeruginosa with each of K. pneumonia andE. coli, markedly reduced pseudomonal biofilm, while co-culture with S. aureus revealed strong support ofpseudomonal pathogenicity and increased its biofilm production.
Isolation and Analysis of Nucleotide Sequences of the 16S rRNA Gene of Pseudomonas aeruginosa Isolated from Clinical Samples Atheer Abdulameer Raheem1 , Hasanain Khaleel Shareef1
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 1 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i1.13729

Abstract

Pseudomonas aeruginosa consider one of the opportunistic pathogens is able to infection almost all bodytissue as a result of having it a variety of virulence factors that contribute greatly to pathogenic events in thehost this bacterium has been responsible for 30% of pneumonia, 19% of urinary tract infections and 10%of bloodstream infections. And leads to nosocomial pathogens causing infections that usually develop lateduring hospital stay. Consequently the aim of this research was to classify and characterize P. aeruginosaisolated from various clinical samples from Iraqi patients by sequencing the 16S rRNA gene.
The Effects of Different Intensive Physical Performances by athletes on Selected Hematological Parameters Shumoos H Alwaid
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 1 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i1.13730

Abstract

The aim of this review study is to compare the effects of different intensive physical performances andcompetitions from several studies include (football, basketball, 24h marathon race and cycling) games onhematological parameters of males players. And to find the one with strongest effect on those parametersamong the performances. The Hematological parameter include white blood cell count (WBC ) , redblood cell count (RBC) count , hemoglobin (HGB), haematocrit (HCT), mean cell volume (MCV) , meancorpuscular hemoglobin (MCH), mean corpuscular hemoglobin concentration (MCHC) and platelet count(PLT). Iron and Feritten level also estimated in one study. When comparing the blood values for all theplayers before and after the competitions period, there were significant differences in prevalence of most ofblood parameters in all studies but the most impact was in 24 h marathon performance of 11 male runnerswho raced for 24 hours around a 400 m oval track, covering at least 100 km of distance. The runners changedcourse every 4 hours and were allowed to rest and freely consume food and water. The blood samples wereobtained from subject in 2 and 9 days prior to competition and after competition. The result was showing thatthe the runners suffering from distinguish blood anemia appear after competition in 2 day. The findings showthat the hematological parameters could be affected by endurance of performance depending on competitiontime period and intensity of physical performance.
Role of CoQ10 and IGFBP-1 in Obese Male Patients with Diabetic Mellitus Type II Dina A. M. Al-Khafajy1 , Maysaa J. Majeed2 , Omar F. Al-Azzawi3 ; Ayad Ismael Khaleel4
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 1 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i1.13731

Abstract

Study the role of CoQ10 and IGFBP-1 in obese male patients with diabetic mellitus type 2. ELISA methodwas used to assay Serum CoQ10 and IGFBP-1. Blood was taken with drawn sample from 30 obese normalpatients with age range (40-60) years, 30 diabetic patients with age range (40-60) years at duration of disease(1-5) years and 30 normal healthy patients. The mean difference between T2DM according to CoQ10(12.5±1.1) was decreased than the mean of IFG (21.8±3.2) (P 0.002) and the mean difference betweenT2DM according to IGFBPs (0.65±0.06) was decreased than the mean of IFG (3.2±0.3) (P 0.000). Whileno significant difference between mean age of DM2 patients (55.5±1.06), and IFG (55.6±0.9) (p 0.90), nosignificant difference between mean BMI of DM2 patients (27.7±0.8), and IFG (27.8±0.5) (p 0.94). therewere significant differences in DM and IFG obese groups (G1 and G2) according to age (51.66 ±2.10,51.80±1.16) P (0.02), however, there were significant differences between DM and IFG in Normal weightgroups (G5 and G6) according to age (59.93±0.94, 51.13±1.80) P (0.00), while no significant differencesbetween DM and IFG in Over weight groups (G3 and G4) according to age (54.93±1.17, 58.00±1.73) p(0.21),there were significant differences between DM2 and IFG in obese groups (G1 and G2) according to BMI(33.70±1.20, 31.11±0.37) P (0.01), ), no significant difference between overweight (G3 and G4) accordingto BMI (27.72±0.30, 27.52±0.34) P(0.66), and no significant difference between normal weight (G5 and G6)according to BMI (21.84±0.45, 21.53±0.50) P(0.65). There were significant differences between DM andIFG in obese groups (G1 and G2) according to CoQ10 (7.2±0.4, 4.9±0.4) P (0.002), and IGFBP (0.3±0.02,1.2±0.19) P (0.005).
Histological and Morphological Study of Carcinoma Breast of Women Aaya Hamid Al-Hakeem1 , Marwa Ahmed Meri1
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 1 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i1.13732

Abstract

Previous studies have referred that the breast cancer, with particular histological traits, can be affected bythe reproductive factors. In the current study, we employed 30 breast cancer cases for women in age (15-55years) to study how factors such as microscopic screening, gross examination, as well as the age, can impacton histological type and grade of tumor. After the organ eradication from the patients, the tissue sampleswere picked, as fast as possible, and placed in 10% formalin directly. In such a way, we maintained thecells and cellular components in a situation that can be described as similar as possible to the living cellsand preserved the antigenicity in order to be processed without any modification. Samples were divideddepending on various factors, such as anatomical location, the nodal status, and tumor relationship tosurgical margin, weight, size, and age. Each sample was sectioned and fixed onto a private embeddingcassette to keep the tissue treatment. The histochemical stains, which is include the eosin and hematoxylin,had utilized to afford a disparity to tissue sections. We found that the majority of the 30 women with breastcancer were at age (31-40 years) and that 12 patients of them were involved left breast, while the other 18patients included right breast. In agreement with previous studies that have investigated the level of riskof histological subgroups, our study concludes that the link between breast cancer risks and reproductivefactors is vary depending on the histological structure of the tumor.
Isolation and Molecular Identification of proteus mirabilis isolated from hospitals in the capital Baghdad Mohammed Kaittan Abed1 , Hasanain Khaleel Shareef2
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 1 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i1.13733

Abstract

Proteus mirabilis a Gram-negative bacteria belonging the Enterobacteriaceae family and that causes severalinfections to patients such as urinary tract infections, middle ear infections, wounds and burns, in additionto other infections. This study aimed to isolate and diagnose Proteus mirabilis bacteria collected fromdifferent samples of infection sources from patients present in many hospitals using traditional diagnosticlike morphological and biochemical tests as well as molecular methods. The Identification system for Gramnegative bacteria GN24 KIT had used to detect Proteus mirabilis species . The results of using this kit wereconfirmed by the molecular diagnosis of bacteria through the PCR technique of the 16S rRNA gene, wherethe confirmation rate was 100%. The PCR sample was analyzed in Macrogen Corporation–Korea for Sangersequencing using ABI3730XL, an automated DNA sequences. the findings were obtained and analyzed viagenius software in order to Synthesis of the phylogenetic tree of the isolated strains that resulted from thediscovery of a new global strain of Proteus mirabilis bacteria and was recorded in NCBI genebank withaccession number (MN 700085) and name (M.K.84 ).
Diabetes and COVID-19 Pandemic: A Potential Mechanisms: A Review Hind Shakir Ahmed1 , Hiba Shakir Ahmed2
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 1 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i1.13734

Abstract

Diabetes is the greatest public condition among patients with coronavirus disease and has been found toaffect prognosis worldwide. It is revealed that hyperglycemia is one of the elements that elevates the risk ofconsequences in these persons. This study designed to analysis the overall features of the novel coronavirusand provide an understanding of the coronavirus disease in diabetic patients, and its treatment.These patients are usually treated with various medications and this review clarify the role of metforminand dipeptidyl peptidase 4 inhibitors as helpful factors in these patients. Recommendations are made onthe probable pathophysiological mechanisms of the association between coronavirus and diabetes, and itsmanagement. Additional study about this association and its clinical managing is necessary
The Effect of Training with Rubber Ropes and Controlling the Resistance Arm on the Response Time and some Biomechanical Variables for the Skill of Sending for Wheelchair Tennis Players Maytham Hadi Mahdi
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 1 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i1.13735

Abstract

Training with rubber ropes is one of the modern training methods that help to develop the absolute strengthof specific parts of the body and according to the skill performance, especially when training with differentmuscle moments that cause the movement of those limbs according to variable resistances, especially forwheelchair tennis players, so the research was applied to a sample of tennis players with chairs Using theseexercises to find out their effect on the serve skill mechanism, this exercises were applied for a period of (10)weeks, on (6) players who are the best players in this competition, and the researcher used foreign and Arabsources and the international information network, observation, experimentation, tests and measurements asmeans of collecting information.A video camera for filming and using kinematic analysis to extract the mechanical variables, and theresearcher came up with several conclusions, including that training according to the results of the analysisand using the change of resistance arms when training with rubber ropes was effective in developing thespeed of the centers of the striking arm parts of the research sample. The exercises led to an improvement inthe technical performance interdependence (the research sample), which inevitably affected the achievementof good achievement, as well as in improving the response time of the research sample