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Indian Journal of Forensic Medicine & Toxicology
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Core Subject : Health,
Articles 5,497 Documents
Detection Levels of Cytokines (IL-6 and IL-18) and Microbial Parameters in Patients with Renal Failure in Diyala Province Wasan A. Wahab Alsiadi; Alaa Mohammed Albayati; Ban Talib Elhaboby
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 2 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i2.14546

Abstract

Current study was conducted in Diyala province for kidney failure patients ( Ibn Sina Center ) for dialysisin Baqubah teaching hospital and started from beginning August 2016 to end April 2017. A total 100 bloodsample had from kidney failure patients, has been the number males 61 and females 39 with age range (10– 88) years and collected 50 of blood sample from oculary healthy individuals act as a control group , hasbeen the number males 25 and females 25 with age range 10 – 88 years . By (ELISA) technique detectionimmunological parameters (IL-6 , IL-18) , and (SRID) for detection microbial parameters (HBV, CMV , T.gondii, HCV) . Result of study expressed that the incidence of disease rate among males 61% more thanfemales 39% with no significant different (P>0.05), also highest rate disease in both age groups (31-50, 51-70) years , while lowest rate disease the age range (10-30 , >70) years recorded with significance different)P <0.05(. So, high levels of ( IL-18) for patients than to control with significance different between studygroups (P <0.05), while (IL-6) was raised in patients compared to control. Also, result showed positivity of( HBV, CMV , T. gondii, HCV ) in patients was (8% , 13%, 10%, 25% ) respectively with high significantdifferent (P<0.05). Conclusions of current study showed male more than female, age period >70 and 51-17year recorded highest percentage infection ,high levels of immunological (IL-6 and IL-18) in renal dialysispatients, as well as to some microbial infected patients with kidney failure. The aim of study is detectionlevels of cytokines (IL-6 and IL-18) and some microbial infection in patients with renal failure.
Mathematical Engineering Model for Studying the Interrelated among Effective Factors in the Sugar Blood Estimation Test Khalid G. Mohammed; Hiba Mahdi Salih; Sara Mahdi Salih
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 2 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i2.14547

Abstract

It is a chronic metabolic disease, which is characterized by high blood sugar, as a result of a defect in thepancreas weakens the production of insulin to the body, and spread type 2 diabetes in humans all over theworld, where there are more than a million and a half million people with diabetes. The most importantfactors contributing to the spread of this disease is eating unhealthy, excessive obesity, lack of exercise,psychological tension and genetic factor, so it is the responsibility of the state, as it must provide healtheducation to its population, and urge them to eat healthy food and reduce excess weight, and encourage themon the practice of r Intifada activity, urging them to westernize the marriage, if any diabetes in the family.Therefore, the independents and dependent variables are included using a statistical program to be analyzedand to find the degree of correlation and impact of the variables among them and to analyze and discuss theresults.
Comparison of Oral Isotretinoin vs Azithromycin in the Treatment of Acne Vulgaris Alaa Sh. Abdulbari; Noor M. Ali; Ahmed R. Abu Raghif; Nadheer A. Matloob
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 2 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i2.14548

Abstract

Background: Acne vulgaris is a chronic inflammatory disease of the pilosebaceous follicles, common inadolescents, characterized by comedones, papules, pustules, cysts, nodules, and occasionally scars. Thisstudy was designed to compare multi B vitamins, folic acid and homocysteine levels in patients withmoderate to severe acne vulgaris with those of the apparently healthy control group and to investigate theeffect of isotretinoin and azithromycin treatments on these biochemical parameters and comparison betweentwo drugs.Methods: This study was conducted on sixty women patients with acne and thirty as a control group. Thepatients were allocated into two groups, A and B, group A was given 500 mg of azithromycin taken onalternative days for 3 months and group B was given 40mg/day isotretinoin for 3 months.Results: The study showed significant differences (p<0.05) in serum levels of vitamins B6, B7, B12 andfolic acid, while no significant difference in serum homocysteine in patient group when compared to controlgroup. The results showed significant positive correlation between serum vitamins and clinical score andsignificant difference were detected in both group when compared between pre and post treatment.Conclusions: The results indicate higher pre-treatment vitamin B12 levels, versus the control group andpositive correlation between clinical score and vitamin B12, support the assertion that vitamin B12 playsa role in the etiopathogenesis of acne vulgaris. Both azithromycin and isotretinoin were effective in acnetreatment but azithromycin has less side effects.
The Association between Serum Nesfatin-1 level and BMI in Iraqi patients with Polycystic Ovary Syndrome (PCOS) Eham Amer Ali; Walaa Ahmed AL-Jedda; Shatha M.J AL-Khateeb; Abdilkarim Y. AL-Samarriae
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 2 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i2.14549

Abstract

Objective: to evaluate the nesfatin-1 levels in addition to other metabolic components in polycystic ovarysyndrome PCOS in a state that to be associated with both functions of ovary and obesity.Methods: A cross-section observational study was carried on total of forty-five (45) women in thereproductive age with polycystic ovary syndrome (23 obese, 22 non-obese) attending Infertility unit andoutpatients clinic of Gynecology and Obstetrics at AL-Yarmouk Teaching Hospital, in addition to forty (40)(30 obese, 10 non-obese) age matched healthy individuals. Serum nesfatin-1, TC, TG, HDL-C, FPG, FPI,E2, TT, LH, FSH and Prol were measured, in addition to HOMA-IR, BMI and LDL-C was calculated.Results: FPG (5.1±0.3 mmol/L), HOMA-IR (2.8±1.1) were significantly higher in PCOS group than theirresults in the control group (4.8±0.2 mmol/L), (2.2±1.3) (P ? 0.05, 0.01) respectively. Nesfatin-1 level(11.1±3.5 ng/ml), TT (1.7±0.3 pg/ml) and LH (6.5±2.8 mIU/ml) in PCOS group were significantly difference(P ? 0.001, 0.05) respectively, when compared their concentration in the control group (6.3±3.0 ng/ml),(0.9±o.1 pg/ml), (4.9±1.5 mIU/ml). Among the patients with PCOS, a strong positive correlation were foundbetween nesfatin-1 and WC (r=0.221 , P ? 0.05) , BMI ( r=0.267 , P ? 0.001), TT (r=0.218, P ?0.001), LH(r=0.263 , P? 0.001), IR (r=0.453 , P ? 0.001), FBG (r=0.257 , P ? 0.01), LDL-C (r=0.228 , P ? 0.05) andTG (r=0.223 , P ? 0.05). Besides that, a positive association were between HOMA-IR and BMI (r=0.460, P? 0.01), WC (r=0.429, P ?0.001).Conclusion: nesfatin-1 gives the impression to play an important action to regulate food intake and energyhomeostasis with a strong positive correlation with WC, BMI, IR, LDL-C and TG.
Detection of Sero-positive Anti- toxoplasmosis Anti-bodes IgG among Women in Baghdad Province Abdullah Abbas Hamzah; Qater Al-Nada Ali Kanaem ALIbady
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 2 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i2.14550

Abstract

A total of 83 serum samples were randomly collected from different centers in Baghdad province, the resultsrecorded in this study which started in July 2018 until the end of November 2018, by using one technique,method ELISA. The results were showed increased the percentage of seropositive anti- toxoplasmosis IgGantibodies at age groups 20 – 29 years, which were 23.9% among women infected with toxoplasmosiscomparative with other age groups. Also showed increase the percentage of sero-positive anti- toxoplasmosisIgG Abs in urban which were 42.9% comparative with rural, which were 8.0%. Also occur increasedsignificantly in percentage IgG Abs in serum of affected women with toxoplasmosis in first and secondmonth from abortion period, which were respectively 17.8% and 16.0%. So increase these antibodies(Abs) in serum of infected women with this disease in 1st trimester period comparative with other months.Therefore so it was necessary to use of early diagnosis for pregnant infected women with toxoplasmosis.
Study Some Kinetic Parameters for Purified Arginase from Two Different Sources: Red Blood Cells and Serum of( Healthy and TypeII Diabetic Patient) Fayhaa M. Khaleel; Essam F.A.Al-Jumaili
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 2 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i2.14551

Abstract

Kinetics parameters for arginase that purified from RBCs, and serum (control, and diabetic patients)revealed that the Km values are (200, 416, and 333mM), Vmax values are (47, 5.5, and 9 U/min),andThe values of catalytic constant Kcat are (174, 45.8, and 81.8 min-1). The effect of atrovastatin was alsostudied on serum arginase, the arginase activity is decreasing by increasing statin concentration, whereinat the lower concentration (0.112 mg/ml) the allosteric regulation percentage is 26% and it is ongoing untilreaching its maximum (85%) at the highest concentration (0.9mg/ml). In conclusion affinity of arginase tothe L-arginine, and its velocity is more in RBCs, and serum patients compared with serum controls, andstatin appears to be an allosteric regulator for arginase.
A Novel Design of Gas System and Develop Culture Medium for the Isolation and Sulfur Reducing Bacteria within Short Time Adnan Neamah Albaidani; Fouad Hussein Kamel; Abeer Younis Mohammed
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 2 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i2.14552

Abstract

The current study has developed a proprietary system and a special device for the supply of oxygen-freenitrogen gas with a mixture of carbon dioxide and 80:20% according to the laboratory conditions required forthe growth of sulfur-reducing bacteria. To find the best medium that fits the bacteria in those environmentswith shortening incubation period, the new medium developed is available in the specification of plantingrich in energy sources, minerals and vitamins and high reduction ability promotes the early growth of sulfurreducing bacteria .
Determination the Gene Expression Levels of adhesins and Extracellular Enzymes Genes in Candida albicans biofilm producer by Quantitative Real Time PCR Technique (qRT-PCR) Najwan Abbas Mohammed; Hamzia Ali Ajah; Nemat Jamel Abdulbaqi
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 2 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i2.14553

Abstract

In the present study, all C. albicans were biofilm producers with variable strength. Molecular study ofvirulence genes correlated with biofilm C. albicans showed that HWP1, ALS1, ALS3, SAP5, PLB1 and LIP8genes were detected in 100% of C. albicans from vaginal and oral infections. In addition to that quantitativereal time PCR technique show that ITS1 was used as the housekeeping gene and was shown to be stablyexpressed throughout all biofilm conditions and HWP1, ALS1, ALS3, SAP5, PLB1 and LIP8 where 100%expressed in all ten tested C. albicans. It was appeared that adhesins genes such as HWP1, ALS1 and ALS3were highly expressed in HBF and less expressed in LBF, whereas in very low BF producers the fold upregulation were not particularly high, but they were over expressed in strong biofilm producers in both ofvaginal and oral isolates. The average of gene expression folding show that SAP5 and PLB1 were highlyexpressed among vaginal isolates rather than oral ones, in contrast, ALS1, HWP1 and LIP8 were predominantexpressed among oral isolates, whereas ALS3 was higher in vaginal isolates than oral with little differences.Gene expression levels by q RT-PCR show that SAP5 and PLB1 were up-regulated in both of HBF andLBF producers, and they were highly expressed among the ten tested isolates. The over expressions ofSAP5 and PLB1 genes were observed in vaginal isolates with high biofilm. The current study found anoverexpression of adhesins such as HWP1, ALS1, ALS3, are responsible in strength of biofilm formationin C. albicans isolated from oral and vaginal infection with different ages and different clinical states,in addition to upregulated of extracellular hydrolytic enzymes genes belong to SAP, PLB and LIP wasimportant in biofilm formation.
International Responsibility for Hiding (COVID-19) Spread Information Muhammad Jabbar Al-Abdali; Amer Abdul Hussein Abbas; Hussein Waheed Abbod ALisawy
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 2 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i2.14554

Abstract

In accordance with the rules of international law, countries that preceded others in exposure to the(COVID-19) have an obligation to inform other countries and the World Health Organization of the outbreakof the said virus as well as to exchange information on laboratory results, source and type of potential risk,number of cases and deaths, the rapid spread of the virus and its medium of spreading between people orthrough means of transportation such as airplanes, ships, etc., or through goods shipped from them and waysto limit its spread. Then, countries that have suffered damage as a result of infection with the aforementionedvirus can claim the necessary compensation towards other countries that have breached their obligationsto exchange information on the spread of the virus on their territories in accordance with the principle ofinternational responsibility. Such compensations are to be determined through international arbitration orjustice or through consulting international and regional organizations or through referring to other peacefulmeans that are agreed upon in accordance with Article 33 of the Charter of the United Nations.
Psychological Suffering of Families, Children with Mental Retardation at Al- Raja Institute for Mental Retardation in Babylon City Haidar Fadhil Abbas; Zainab Neamat Jumaah; Mansour Abdullah Falah
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 2 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i2.14555

Abstract

Objectives: To assess psychological suffering of families of children with mental retardationMethods: Descriptive study conducted among 60 caregivers, they are using self-reported questionnaire togathering data about the phenomenaResults: (50% & 44%) of families had moderate and severe psychological suffering respectively. The grandmean is (2.15) at moderate level of suffering.Conclusion: the families have moderate to severe psychological suffering due to caring child with mentalretardation. They are need for psychosocial support.