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INDONESIA
Indian Journal of Forensic Medicine & Toxicology
Published by Official Organ of Indian Association of Medico-Legal Expert
ISSN : -     EISSN : -     DOI : -
Core Subject : Health,
Public Health
Arjuna Subject : Kedokteran - Epidemilogi
Articles 5,497 Documents
 417   418   419   420   421 
Effectiveness of Giving Secang Wood Extract (Caesalpinia Sappan L) Against IL-6 And IL-10 Levels in Balb / C Mice With Vulvovaginalis Candidiasis Sri Wahyu; Firdaus Hamid; Mochammad Hatta; Khairuddin Djawad; Agussalim Bukhari; Rosdiana Natzir; Alfina Baharuddin
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 2 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i2.14567

Abstract

The aim of this study was to test the effectiveness of secang wood extract (Caesalpinia sappan L) onIL-6 and IL-10 expression in Balb / c mice with vulvovaginalis candidiasis. This type of research is anexperimental laboratory, with a control group design using experimental animals as research objects. Theresearch subjects were BALB / c mice weighing 35-40 grams, aged 10-12 weeks, the number of experimentalanimals needed in this study was 18 for 3 random groups, each group being 6. Analysis and data processingusing the excel program SPSS Repeated ANOVA Test was used to measure differences in cytokine levels.IL-6 levels in group 1 (control) where the value of IL-6 expression after infection (H1) was 4309.40 pg /mL(IQR value 3803.8-4963.5) after treatment (H7) in the control group increased by 5578.12 pq / mL (IQR5330.3 - 6162.9). In group 2 that were given fluconazole and secang wood extract, IL-6 levels tended todecrease by 3516.4 pq / mL (IQR: 3070.4-4061.6) Secang wood after infection decreased from 3417.34 pq/ mL to 2782.97 pq / mL after treatment. In Group 2 that was given fluconazole and secang wood extract,IL-10 levels increased by 1414.8 pq / ml (IQR: 1061.7- 3158) after infection, to 3268.35 pq / ml (IQRvalue: 1789.9-3709.6) after treatment. given secang wood after infection increased from 2032.67 pq / ml to3091.83 pq / mL after treatment. The p value is 0.008. Obtained the effect of secang wood extract in reducinglevels of Interleukin 6 and can increase the value of IL-10 levels after administration of secang wood extracton candidiasis vulvovaginalis
Expectant Management in Tubal Ectopic Pregnancy in ThiQar Province: Interventional Comparative Trial Alaa Hussain Ali Al-Nasir
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 2 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i2.14568

Abstract

Background: Ectopic pregnancy one of the life threatening condition, that can’t be prevented but canmanaged safely. Rationale: rolling out of surgical intervention to medical management is hope of all, eventhough surgeon. Aim of the study: to compare between the expectant and surgical management of tubalectopic pregnancy. Patients and Methods: Single blinded, controlled and interventional study conductedin Bint Al-Huda teaching hospital in Thi-Qar-Iraq, extended all over the 2019 since January till last weekof December . Totally (74) patients enrolled in the study, all of them were complained from tubal ectopicpregnancy, questionnaire, B-HCG, Trans- vaginal US were the main tools of follow up, Results: The targetpatients for our study was 116, 34 of them were excluded, 16 was with positive fetal heart, 20 were hadhemoperitonium extend beyond the pelvis at the time of presentation and 8 patients were patients refusefallow up (expected management). Most of them(40%) were older than 34 years, followed by (32.5%) within age of 32.5%, while the youngest age group occupying minimal proportion (27%), According to ?-HCGconcentration most of them (58%) were with <1500 mlU/ml concentration. Conclusion: Highly proportionof tubal pregnancy managed by follow up without surgical intervention. ?-HCG titer and trans- vaginal USare the golden keys of management
COVID 19 Patients /Southern of Iraq: Character and Dermatologic Manifestations Ahmed Abdul Hussein Kawen; Ali Abid Saadoon
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 2 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i2.14573

Abstract

Background: the spread of coronavirus diseases (COVID-19) in China and then around the world wherethe current study explores the link between skin manifestations and COVID-19. Methods: A cross sectionalstudy including all diagnosed cases of COVID-19 in Thi-Qar and Al-Muthana governorates, where startedby the diagnosis of the 1st case in Thi-Qar province, and ended with the 21th of April 2020, the cases weredistributed as 62 cases from Thi-Qar and 54 cases from Al-Muthana, information had been gathered fromCOVID -19 isolation unites in the two main hospitals of isolation, Al-Husain teaching Hospital and AlMuthana teaching hospital. Results: The result showed that there are 116 cases of SARS-COV2 infectionwas recorded in Thi-Qar and Al-Muthanna, the high percentage of infection was detects in the middle adult80(69%) in the age group over 60 years old. The distribution of infection according to the gender revealedsignificant differences where the males comprise (87.75%) of cases. The direct contact route of transmissionwas predominant among patients 101 (87.1%). Also, the highest percentage was live 110(94.8%). Accordingto the results there was a negative relationship between the two variables was detected, there is no correlation.So, there is no correlation in skin manifestations according to the system involvement among COVID-19infected cases with the pearson correlation (0.327). The results show non-statistical significance in skinmanifestation according to biography among only who had dermatological lesions at p value (0.248). Also,there are non-statistical significant in source of infection according to skin manifestation and no correlationbetween skin manifestations and death with corona virus. Conclusions: It can be concluded from the currentstudy that there is no close correlation between skin manifestations and COVID-19 infection, a very weakdirect relationship because some patients may not show any symptoms and these are considered negativesigns, meanwhile the unique skin lesion are zinc like deficiency( acrodematitis enteropathica )not reportedin any other areas.
Retrograde Intra-Renal Surgery Versus Percutaneous Nephrolithotomy in Management of Renal Stone 10-20 Millimeters, A Comparative Clinical Study Ali Abdul Baqi Isamel; Firas Abdullah Noori Al-Baghdadi; Riyadh Adel Jaed AbdulAzez; Muntadar Easa Mahdi
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 2 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i2.14574

Abstract

Purpose: comparison the efficacy and safety of percutaneous nephrolithotomy (PNL) and retrograde intrarenal surgery (RIRS) in treatment of renal stones. Patients and Methods: Records of patients who underwentsurgery for renal stone were retrospectively reviewed, for two years from the beginning of 2017 till the endof 2019. Patients who had renal stones between 10 - 20 Millimeter and located in different renal caliceswere included, patients who underwent percutaneous nephron-lithotomy PNL and retrograde intra-renalsurgery RIRS were defined as Group I and Group II, respectively. Patient criteria (age, sex, BMI); the stonecharacteristics; time of procedure, fluoroscopy and hospitalization; stone-free and complications (bleeding,pain, infection, visceral injury, conversion to open surgery, and need for blood transfusion) were evaluatedbetween the treatment groups. Result: There were no significant differences in terms of age, gender, BMI,laterality, number of stones, Hounsfield units and surface area characteristics of the stone between the PNL(n 25) and RIRS (n = 35) groups (P = .558, P = .278, P = .375, P = 0.051, P = .053, P = .064, P = .642, P =.080, respectively). Stone free rate was 59.6% (n=28) in PNL, and 88.6% (n=31) in RIRS (P=.004). 1st or2nd degree complications according to Modified Clavien Classification developed in 10 patients (21.3%) inGroup I and 1 patient (2.9%) in Group II (P = .015). The 3A or 3B complications were similar in groups (P= .077). Time of procedure, fluoroscopy and hospitalization were significantly lower in Group II (P < .001,P < .001 and P < .001, respectively). Conclusion: RIRS is more effective and more reliable procedure thanPNL with higher stone-free and lower complication rates in treatment of single renal stone (10 t0 20 mm).
Radiographic Assessment of Post-Endodontic Pain Sameer Hatem Abdul Haleem
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 2 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i2.14575

Abstract

Aim:To radiographically assess and identify the factors that influence post-endodontic pain (PEP) in patientsreceived nonsurgical root canal treatment. Study Design: a longitudinal study. Place and Duration ofStudy: the study performed on 375 patients (200 male, 175 female), aged 15–65 years randomly attend Dr.Sameer Hatem private clinic in Karbala between 2014- 2019 Method. the complete history of patients wastaken, clinically examined and then radiographically examined by CSN x-ray machine and Xpod digitalsensor to identify the possible factors and assess the status of previously treated teeth, the patients dividedinto groups according to the age, causative factors, and the onset of pain from patients’ chief complain.Results:(Table.2) shows the differences in numbers and percentages of overall patients according to theonset and the causative factors of pain after root canal treatment, the high percentage of the pain of 102/(27.2%) of patients was due to overextension of filling material, (most of these patients were suffering fromspontaneous pain 47.05%). Followed by 78/(20.8%) which were due to failure of treatment due to underfilled root canal (most of them 34.61% have intermittent pain). Conclusion: Periapical x-ray radiographyis a valuable technique to identify the causative factors of post endodontic pain and evaluate the success ofRCT and the status of endo treated tooth and periapical tissues. All procedural errors can not be depicted onradiographs.
Evaluation of Hinge Position on Corneal Sensation and dry Eye after Laser in Situ Keratomileusis (LASIK) in Thi-Qar Governorate Wajida Saad Bunyan
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 2 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i2.14576

Abstract

Purpose: This investigation planned to assess the impacts of Laser In Situ Keratomileusis (LASIK)with prevalent and nasal pivot areas on corneal sensation and dry eye condition. Planned randomizedsimilar investigation was completed from February 2018 to December 2019. The subsequent term werepreoperatively evaluated just as 1week and 1,3,6 months postoperatively. This examination included 600eyes of 420 patients (180 guys and 240 females), all patients went through LASIK medical procedure forrectification of nearsightedness as well as nearsighted astigmatism utilizing MEL 90 Excimer laser for stromalremoval , Moria M2, SBK microkeratomes were utilized to make a prevalent and nasal pivoted folds. At thepoint when patients chose to have medical procedure, they were randomized to get nasal or predominantpivot medical procedure based on the randomization succession. Focal Cochet-Hat esthesiometry, Schirmerfundamental tear discharge test, tear film separation time (TBUT) were assessed preoperatively and at multiweek , 1, 3, and a half year postoperatively. After medical procedure, the corneal sensation diminishedessentially in both nasal-pivot and prevalent pivot folds at multi week however got back to gauge by halfyear. The Schirmer essential emission test esteems were not altogether changed postoperatively in the nasalpivoted and predominant pivoted eyes. TBUT diminished inconsequential at multi week and multi monthpostoperatively and recouped by 3 months after medical procedure in the two gatherings. There were nohuge contrasts in all the abstract and target boundaries tried between nasal-pivoted and unrivaled pivotedfolds whenever point. There is no intraoperative and postoperative inconveniences in everyone’s eyes.There was a huge decrease in corneal sensation following LASIK in nasal and predominant gatherings.Sensation improved at untouched stretches and re-visitations of nearly, preoperative levels around a halfyear postoperatively. Related with the corneal denervation is a prompt postoperative increment in dry-eye asestimated by TBUT and schirmer test that improved utilizing oils and with ensuing visits.
Phenotypic and Molecular Detection of Pyocin from Multidrug-Resistant Pseudomonas aeruginosa Isolated from Various Pathogenic Ahmed Yas Saeed; Dhyaa Fandi Ahmed; Mahmood Khlaf Saleh; Adnan F. Alazzawie; Mostafa Qahtan Mostafa; Fatima Mustafa Mahdii; Nedaa Wasmi Shehab; Omar A.Mohammed Al Hashimi
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 2 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i2.14577

Abstract

This study included collecting (114) pure isolates of Pseudomonas aeruginosa, distributed over wounds(39) isolates, burns (31) isolates, urinary tract infections (23) isolations, ear infections (12) isolations, andrespiratory infections (9) Isolates. The test for the sensitivity of the bacteria to (14) types of antibioticsshowed a clear variation in their resistance to antibiotics, as all isolates showed 100% resistance toAmpicillin and Novabocin, Nalidixic acid by 93.8%, and Bacitracin by 87.7%, while they had low resistanceto Ciprofloxacin, 21%, Cefotaxime 19.2%, and Chloramphenicol 18.4%. While the results of the phenotypicdetection of pyocin showed the presence of (85 isolates, at a rate of 74.5%), producing Pyocin, while (29isolates, at a rate of 25.4%), it showed its inability to produce Pyosin. As for the molecular detection of thePrtN gene, which is one of the most important genes responsible for the production of Pyocin, It was shownthat (17 isolates, 77.2%) possess this gene, while (5 isolates, at a rate of 22.7%), they did not possess thisgene.
Evaluation of Lipocalin-2 and Visfatin, and Vitamin (D,C, and E) in Serum of Diabetic Patients with Chronic Periodontitis Anas Qahtan Hamdi; Entedhar R. Sarhat; Nagham Hasan Ali; Thuraia Rifaat Sarhat
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 2 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i2.14578

Abstract

Objective: The aim of the present study is to verify the hypothesis that salivary and serum lipocalin-2and visfatin, and vitamin (D,C, and E) used as indicators for chronic periodontitis among DMT2 patients.Subjects and methods: We enrolled 41 type 2 diabetic patients with chronic periodontitis -18 males and 23females, aged 60± 14 years and 49 controls- 26 males and 23 females, aged 61.8 ± 12.5 years. Blood sampleswere collected after an overnight fast and routine biochemical parameters such as glucose, lipocalin-2 andvisfatin, and vitamin (D,C, and E)were determined in all samples. Data were considered significant at a levelof p < 0.05.Periodontitis status was established using classic clinical parameters, Plaque index (PI), gingivalindex (GI), probing depth (PD) and clinical attachment level (CAL). Results: 1) The mean serum of bloodglucose, Visfatin, and LCN2 were higher in patients group than in those with normal control group (P<0.001for all comparisons) ; 2) patients with had a lower Vitamin D,C, and E than those with a normal group (P <0.001 for all comparisons).Conclusions: The activity of lipocalin-2 and visfatin in saliva and serum can beuseful in diagnosis, monitorization and treatment of this disease. Further studies are needed to elucidate therole of lipocalin-2 and visfatin in periodontitis and systemic disease interactions.
In Vivo Treatment of Giardia lamblia by Plantago lanceolata L. extract and Investigation some Serological Parameters and Histopathological Changes Ashraf Jamal Mahmoud Zangana
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 2 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i2.14579

Abstract

Giardia lamblia samples were taken from patients at Salah al-Din General Hospital /Tikrit, suffering fromGiardiasis from October 2018 until March 2019. cysts of G. lamblia was isolated and infected in laboratorymices Balb/c and then therapeutic attempt was made with water extract of Plantago lanceolata in threedifferent concentrations .and some biochemical parameters have been studied through rate of changes inCholesterol, Triglycerids, Total protein and some of liver enzymes (AST) Alanine transaminase, (ALT)Aspartate transaminase, and response of infected mice for treatment with water extracts.A significant decrease was observed in concentration of lipids in general. The decrease was significant inconcentration of Cholesterol and Triglycerides and total protein in laboratory mice. The lowest concentrationwas achieved when using extract with 0.5 ml, 121, 31, and 4.311 mg/dl Respectively, The highst concentrationwhen using extract was with 2 ml, 180, 36, and 5.220 mg/dl Respectively, compared to control group 184,37 and 5.040 mg/dl Respectively, Significant changes were also observed.As for concentration of both AST/ ALT, the results showed significant changes in their concentration ininfected mice. level of decrease was significant in their concentration. The lowest concentration of AST wasat 0.5 mL, 18 IU/L, and ALT 15 IU/L at 0.5 mL of extract, The highest concentration of AST was at 2 mL, 30IU/L, and ALT 29 IU/L at 2 mL of extract compared to control group of 28 IU/L. Significant changes wereobserved in concentration of AST and ALT after treatment with therapeutic extract Above.The microscopic examination of tissue sections of infected mice showed presence of a detachment of somelining cells of colon. presence of leukocyte infiltration at base of mucous glands was also observed. Thisinfiltration was extended to smooth muscle layer forming colon wall. colon cavity consisted of large massesof mucus. In liver, there was an enlargement of hepatic cells and presence of degeneration of nuclei of thesecells, and found small concentrations of inflammatory cells between hepatocytes, some central veins in liver,and observed lymphocytic infiltration.
The Caries Experience in the Smoker and Non-Smoker among College Student Azhar A. Hussein; Maha Issam; Hatham Yunis
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 2 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i2.14580

Abstract

Dental caries is the scientific term for tooth decay or cavities. It is caused by specific types of bacteria. Theyproduce acid that destroys the tooth’s enamel and the layer under it, the dentin. The bacteria turn sugar andcarbohydrates (starches) in the foods we eat into acids. Smoking is also a global and national health problemand is one of the most significant health risks that impact all age groups.The Study Aims to investigate the effects of different tobacco smoking methods and their relation to dentalcaries in comparison to non-smoker students.Material and Method: A random sample of 336 students from Tikrit university aged 19-24 years, the samplegrouped to cigar, shisha, cigar and shisha together and non-smoker groups. Dental caries was recordedaccording to WHO criteria (1987) were decayed, missing and filled with permanent teeth (DMFS). The datawere analyzed as a descriptive statistic includes frequency, percentage, mean, and for statistical analysis ofthe data using T- test and one- way ANOVA test to detect the significance of the relation between variousvariable.Result: the result of this study showed that the severity of dental caries higher in smoking cigar and smokingshisha than in the non-smoking group with statistically highly significant.Conclusion Nicotine may be increasing the incidence and severity of dental caries. So that, nicotine mightbe considered as a risk factor for inducing of dental caries.

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