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INDONESIA
Indian Journal of Forensic Medicine & Toxicology
Published by Official Organ of Indian Association of Medico-Legal Expert
ISSN : -     EISSN : -     DOI : -
Core Subject : Health,
Public Health
Arjuna Subject : Kedokteran - Epidemilogi
Articles 5,497 Documents
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The Effect of Black Cumin (Nigella sativa) Oil Supplementation on Hematotoxicity Induced by Benzene in Gasoline Vapors from Gas Stations in Male Wistar Rats Ikhram Hardi S; Merryana Adriani; Tri Martiana
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 3 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i3.15810

Abstract

This study aimed to prove the effect of black cumin oil supplementation through analysis of levels of CYP2E1, MDA, GSH, and hematological profiles in experimental animals, Wistar rats, which were exposed to benzene in gasoline vapors from gas stations. Sixty-four experimental Wistar rats were divided into eight groups with eight rats each, two control groups (C1 and C2), and six experimental groups (T1, T2, T3, T4, T5, and T6). Blood samples of experimental rats were taken through intracardiac with ketamine-xylazineacepromazine anesthesia on day 15 for group C1, C2, T1, T3, and T5; and day 29 for group T2, T4, and T6. The ELISA method measured the levels of CYP2E1, GSH, and MDA in this study, while the hematological profile used a hematology analyzer. This study indicates that benzene in gasoline vapors exposure caused significant hematotoxicity (P <0.05). Supplementation of black cumin seed oil at a dose of 2.5 ml/kg, 5 ml/kg, and 10 ml/kg, all of which have the potential to provide a protective effect against the hematotoxicity of benzene in gasoline vapors through increased internal antioxidants (GSH). The GSH can play a role in the mechanism of vapor metabolism of substances in gasoline vapors in the body through decreased CYP2E1 levels and decreased MDA levels. Further research is still needed with a more extended treatment duration to ascertain the chronic effects of benzene hematotoxicity on the genomic pathway to assess black cumin’s role, whether in the form of oil, powder, or other forms of extraction.
Knowledge and Health Behavior about Vitamin D during Epidemic COVID-19 among Female University Students Iman A Jaber
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 3 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i3.15811

Abstract

Background:Vitamin D deficiency it considers a global health problem and a significantly linked with skeletal and non-skeletal problems. Prevention can be kept by sun exposure or supplementation and to lower extent by dietary intake.Objective: to assessedknowledge and health behavior regarding the vitamin Dduring epidemicCOVID-19 among female university studentsMethodology: A descriptive study was conducted, total of 400femal student aged between 20 and 30years who study in university,institute, from7thJuly 2020to 30September2020,by using electronic formand freely agree to participate in the research project. The validity was estimated through a penal of experts related to the field of study. Datawasanalystthrough the implementation of descriptive and inferential statistical analysis.Results: The results of this study show that the knowledge of thestudy samplewaslow regarding student knowledge in some item while thereis high score about the importance of vitamin D, so us the grand mean above the cut of point duo to the behavior Recommendations: It was recommended increasing awarenessabout the importance of vitamin D and guidelines on how to obtain it were necessary by (food, sun exposure)especially in period of epidemicCOVID-19.
The Effect of Excessive Ginger Intake on the Health of Mice and Liver Tissue Khloud Adnan AL-Lehaibe; Tamara Amer Taha
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 3 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i3.15812

Abstract

Introduction: Spices are one of the main ingredients frequently used in Arab and Asian kitchens. Therefore, we must research their harms in the service of society. Objective: This study aimed to investigate the effect of excessive ginger consumption on the phenotypic and histological structure of the mice liver. It is important to have a clear view of the spices that play a major role in damaging organs. Methodology: About 20 mice were used. I was orally (1g) to ginger for 50 days. that anesthetization, separating the liver, fixing by formalin, using the routine method to preparation block and sectioning (5um) then coloured with H&E. Results: Symptoms was the loss of weight, high temperatures, as well as the Gangrene at ends of the Ear, Tail. the liver appearance of severe congestion with a dark red colour, accompanied by bleeding and the appearance of fluid-filled swelling in the liver, forming what is called the liver abscess. Microscopy indicated a loss of the normal structure of the liver tissue. The sections also showed the emergence of the stages of programmed death of cells.Conclusion: We concluded that consuming spices in large quantities will lead to toxic liver toxicity, but it is not dangerous.
Effect of Extreme Consumption of Clove on the Morphology of Mice and Liver Tissue Khloud Adnan AL-Lehaibe
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 3 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i3.15813

Abstract

Introduction: Flavors are one of the main materials used in the world kitchens. Therefore, we must research their harms in the service of society. Objective: This study aimed to investigate the effect of too much cloves consumption on the morphological and histological structure of the mice liver. It is important to have a clear view of the excitements that play a major role in damaging organs. Methodology: About 20 mice were used. I was orally (1g) to ginger for 50 days. that anesthetization, separating the liver, fixing by formalin, using the routine method to preparation block and sectioning (5um) then coloured with H&E. Results: symptoms was decrease in weight and signs of dehydration and hair loss,. the liver appearance of severe congestion with a dark red colour, accompanied by bleeding and the appearance of necrosis in the liver. Microscopy indicated a loss of the normal structure of the liver tissue. The sections also showed the emergence of the stages of programmed death of cells.Conclusion: We concluded that consuming spices in large quantities will lead to toxic liver toxicity, but it is not dangerous.
The Questions of Compulsory Organ Donation: The Trolley Dilemma - A Discussion From Ethical, Legal, and SocialEconomical Perspectives Khoa Tran; Anh Tuyet Nguyen
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 3 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i3.15814

Abstract

The Covid-19 pandemic has inflicted disastrous damages on various aspects of human lives, especially the healthcare sector. The shortage of beds, medical staff, and other facilities in hospitals posed an acute dilemma over who should be given precedence in the treatment process and whether a more seriously ill person should sacrifice for people with less severe illness. With an interpretative approach, this short research article discusses the above questions by using compulsory organ donations as a proxy. After evaluating the compulsory organ donation from the ethical aspect, researchers then dig into the issue from legal and socioeconomic perspectives. The authors are convinced by Kant and Nozick’s proposals on ethics and justice regarding organ donation and patient sacrifice. The research also found out that the problem is not merely limited to the question of morality but also extended to an opt-out system for ensuring social welfare. Finally, the paper encourages medical practitioners, legislators, and social activists to make decisions about medical-legal issues based on interdisciplinary views.
The Commonest Clinical Presentation of Gallstone Disease in Laparoscopically Cholecystectomized Patients Khairallah Muzhir Gabash; Hawra Khairallah Muzhir
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 3 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i3.15815

Abstract

Cholelithiasis is the presence of one or more gallstones within the gallbladder. Gallstone disease is a common cause for surgical intervention all over the world.The objective of the study is to determine the order of frequency of clinical presentations for cholelithiasis in laparoscopically cholecystectomized patients in ALKarama teaching hospital.A total sample of 156 clearly documented gallstone disease and laparoscopic cholecystectomized patients were involved in the present study. In the current study, 156 laparoscopic cholecystectomized patients; (34) males and (122) females, ages range between 20 and 69 years with a mean (m=39.24±11.7). Common factors that justified the indication for laparoscopic cholecystectomy (LC) were found in the majority of patients with asymptomatic and mild GI presentation those factors include microlithiasis < 3mm, risk for gallbladder CA, history of bariatric surgery, coexistent morbidities like diabetes mellitus (DM) and hemolytic anemia (HA) or the LC was done in concomitant with another laparoscopic surgery.From the present study, we concluded that the mild GI symptoms represented by dyspepsia, nausea, flatulence and constipation, were at the top of clinical presentations for gallstone patients who underwent LC. The distribution of cases was higher in the 4th decade of life with female predominance.
The Effectiveness of Project-Based Learning atThe Level of Health and Sports Awareness for Students of The College of Applied Studies and Community Service Khalid Hassan Alshehri; Mona Mostafa Abdo Sakoury; Haitham Fayez Mahmoud Akl; Nagwa Ibrahim Albadaly; Hana Ahmed Saud Ababtain; Yahia Mohamed Mohamed Ali Abd El Gaid
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 3 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i3.15817

Abstract

Effectiveness of project-based learning at the level of health and sports awareness for students of the Collegeof Applied Studies and Community Service. the research aims to identify the effectiveness of projectbasedlearning at the level of health and sports awareness for students of the College of Applied Studiesand Community Service. researchers used the experimental method for its suitability to the research. Theresearch sample was deliberately chosen from first-level students, who are (113) students from the Collegeof Applied Studies and Community Service, whose ages range from (18-20) years. Measurements weretaken and data collected through questionnaire forms.Among the most important findings of the research is the existence of a statistically significant relationshipat the level of (0.05) in all aspects of students’ health and sports awareness, the effectiveness of the projectlearning method as one of the health education methods in the learning process.Through this, the following recommendations were reached to activate the project learning method fordifferent academic courses and use it on different groups in society, to pay attention to the practical aspectas a basic method in teaching health and fitness, which helps to confirm the practical practice of informationrelated to sports and health in the daily life of students andintegrating educational messages in the curriculacourses at different academic levels.
Assessment of Serum Vit D and Serum Ferritin in Female Pattern Androgenic Alopecia Khalid Ibrahim Jasim; Abdul Satar Mohammed Ali Khidhair; Ghassan A Hussain
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 3 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i3.15818

Abstract

Introduction: Androgenic Alopecia (AGA) is a non-scarring alopecia that affects both men and women. Itis characterized by a progressive miniaturization of hair follicles with a characteristic pattern distribution ingenetically predisposed men and women.Aim of the study: To assess the level of serum ferritin and vit D3 in female pattern of androgenic alopecia.Patients and method: A prospective case control study carried out at Department of Dermatology inBaladgeneral hospital, Iraq at the period from the first of January 2019 to the end of Dec 2019.Results: serum vit D3 for patients was (22.8 ± 11.5) in case group and (34.4±5.7) in control group, whilefor S. ferritin was (35.7±5.0) in control group and (44.8±7.3) in control group. Vit D3 deficiency (<20 mg/dl) were found in 68% of patients while 30% with vit D3 insufficiency.In three grades of severity, it was found that vit D3 level in grade I was (24.2±6.9), in grade II (20.7±7.2),and in III (18.9±9.2). While for ferritin was (37.4±10.8) in grade I, (30.7±9.4) in grade II, and (25.9±12.1)in grade III.No significant differences were found between the three grades groups regarding serum vitamine D3, whilesignificant difference present among S. ferritin. The sensitivity of the vit D3 test to predict the disease were(90.9%), the specificity was excellent (95.1%), while for ferritin the sensitivity was (88.3%), the specificitywas (89.0%).Conclusion: Serum Vit D3 and Ferritin concentrations were significantly decrease in female with androgenicalopecia.
Study the Effects of Heavy Metals (Lead and Cadmium) on Some Biochemicalparameters of Dairy Cattle in Baghdad Province Khalid Sh. Salman; Tamara N. Dawood
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 3 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i3.15819

Abstract

This study investigatesthe effects of heavy metals (Lead and Cadmium) on some biochemical parametersof dairy cattle in Baghdad province(Taji, Abu Ghraib, Al-Fudilia, Letifia and Youssoufia)regions.Thirtysamples of blood from dairy cattle in five different regions were taken to measure the Lead and Cadmiumconcentration by atomic absorptionwhile serum were collected for measuring, liver enzymes (aspartateaminotransferase AST and alanine aminotransferase ALT) activity,Serum total protein, serum albumin,serum globulin and serum creatinineconcentration.The results showed a significant increase (p< 0.05) in theleadand cadmium ion concentration in the blood sample of the dairy cowsin Youssoufia region comparedwith other region. On the other hand, the total protein and globulin concentration of the dairy cattle in AbuGhraib region recorded significantly (p < 0.05) higher value compared with Letifia region. While Albuminand creatinine concentrations showed non-significant (p > 0.05) differences among the different regions.Liver enzyme AST concentration showed significant increase (p < 0.05) in the serumof dairy cows in Letifiaand Youssoufia regions. However, serum ALT were increased significantly(p < 0.05) in Letifia than AbuGhraib region.Concluded from thisstudythatdairy cattle inLetifia and Youssoufia regions were subjected topollution with heavy metals which caused Increased heavy metal content in the blood of cattle and affecttheir health by increased the concentration of liver enzyme and reduction of total protein in the blood ofdairy cattle compared with other region in Baghdad province.
Assessment of IL-6 , IL-23 and Serum amylase Levels in Patients with Enteric Fevers Khalil Ismail A. Mohammed; Wifaq M. Ali Al-Wattar; Suha A. Al-Fukhar; Saad Hasan Mohammed Ali; Jinan M. Mousa
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 3 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i3.15820

Abstract

The study was carried out during the period of March 2019-January 2020 for the detection of Salmonellosis in102 suspected patients with age group ranged from 17 - 69 years, who attended Baghdad teaching hospitals,that had been examined and defined as suspected cases by a specialized physician with the recording ofclinical manifestation. The diagnosis is done by the immunochromatography method, a blood sample wastaken from each patient as well as other 30 healthy control matching in age and gender. The study includedmeasurement of the level of interleukin -6,23 and Amylase activity in sera of patients and healthy control.The result indicated that anti –salmonella IgM positive in 54 cases, anti- salmonella IgG positive in 50cases, and 18 positive cases with both IgM and IgG. The Level of interleukin 6,23 increased significantlywhile the serum amylase activity decreased significantly in patients sera in comparison with healthy control.

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