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INDONESIA
Indian Journal of Forensic Medicine & Toxicology
Published by Official Organ of Indian Association of Medico-Legal Expert
ISSN : -     EISSN : -     DOI : -
Core Subject : Health,
Public Health
Arjuna Subject : Kedokteran - Epidemilogi
Articles 5,497 Documents
 508   509   510   511   512 
The Difference in Interleukin-8 (IL-8) on Degrees of Acne Vulgaris Severity Hendra Tarigan Sibero; Eryati Darwin; Yan Wirasati; Satya Wydya Yenny; Suharmanto
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 3 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i3.15798

Abstract

Background: Acne vulgaris (AV) is a follicular disease that occurs most often and affects the area containing sebaceous gland follicles, including the face, back, and body. This is a multifactorial condition. The prevalence of acne vulgaris (AV) is still high both in the world and in Indonesia. As many as 80% of AV is found at the age of 11-30 years and almost 100% in adolescents. Various factors can trigger the onset of AV which can lead to severe complications. Aim: This study looked for the difference in interleukin-8 (IL-8) on degrees of AV severity. Materials and method: This study was an observational analytic study with a crosssectional approach. The research was conducted at the Diniyah Putri Islamic Boarding School, Lampung Province, Indonesia, in August 2020. The independent variable in this study was the AV degree, while the dependent variable was the IL-8 level. The sampling method in this study was consecutive sampling, as many as 63 AV patients. The research material is serum from venous blood. Examination of interleukin-8 levels using the ELISA method. Data analysis was univariate to find the mean and standard deviation of IL-8 levels, as well as the frequency distribution to determine the degree of AV. While the bivariate analysis was to determine the difference in the mean of IL-8 levels in AV patients. Results: The mean of IL-8 levels in AV patients was 38.53. Most of the AV patients are in a severe category. Further analysis found no difference in the mean of IL-8 levels between moderate and severe AV degrees. Conclusion: There was no difference in the mean of IL-8 levels in moderate and severe AV patients, but the IL-8 levels at severe AV degrees were higher than moderate AV degrees.
Patient Satisfaction and Complaints Handling in Health Services Quality Improvement Effort at Sijunjung Public Hospital in West Sumatra, Indonesia Isniati; Rizanda Machmud; Nusyirwan Effendi; Rima Semiarty
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 3 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i3.15799

Abstract

Complaint handling is one of the many strategies for improving health services. It is recognized that patients’ satisfaction is an indicator of the quality of care. A survey on public services revealed that public satisfaction at Sijunjung Hospital was 43.78% in the year 2015 but decreased to 40.18% in 2016. This decrease in public satisfaction is due to patients’ complaints. From 2015 to 2016 there were 198,739 complaints while from 2016 to 2017 the number increased to 208,415. The purpose of this study is to determine the factors of patient’s dissatisfaction with health care services and complaint handling to improve health services quality at Sijunjung Public Hospital. This study uses the mixed method. The initial phase of this research is done by quantitative approach using a cross-sectional design in the form of data collection and analysis. The study involves a qualitative approach using observation method, in-depth interviews, Focus Group Discussions. The study reveals that only half of the inpatients, outpatients, and Emergency Unit patients get excellent health services at Sijunjung Public Hospital. The results of the study suggest that satisfaction of patients requires an individual analysis of the patient’s needs; implementation in the health care system of functions that meet these needs.
Ecological Analysis of Stroke in Indonesia in 2018 Izza Dinalhaque Pranatasari; Agung Dwi Laksono
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 3 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i3.15800

Abstract

Stroke is one of the significant causes of disability and death worldwide and is classified as a catastrophic disease in Indonesia. The study aims to analyze ecologically the factors related to theprevalence of stroke in Indonesia. The authors conduct a research using secondary data from the 2018 Indonesia Basic Health Survey that used all the provinces as samples. Apart from theprevalence of stroke, four other variables analyzed as independent variables were diabetes mellitus, theprevalence of hypertension, theprevalence of obesity, and the percentage of the population with alcohol consumptionin the past month. Data were analyzed using a scatter plot.The study results found thatthe higher the prevalence of diabetes mellitus, hypertension, and obesity in a province, the higher the prevalence of stroke. However, the higher the population percentage with alcohol consumption, the lower the prevalence of stroke in that province. The three variables, which are the prevalence of diabetes mellitus, hypertension, and obesity, were positively related to the prevalence of stroke in Indonesia. The population percentage with alcohol consumption was negatively associated with the majorityof stroke in Indonesia.
Deleted
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 3 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i3.15801

Abstract

T
Mechanism of Corneal Epithelial Cells Death by Infection of pseudomonas Aeruginosathrough Analysis Expression of Caspase-1, TNF, RIPK1, RIPK3, Caspase-3 in Rats Model Ismi Zuhria; Nurwasis; Eddy Bagus Wasito; Winarto; I Ketut Sudiana; Reny I’tishom; Nyilo Purnami
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 3 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i3.15802

Abstract

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The Effect of Brown Seaweed (Sargassum sp.) Extract on Apoptosis Process in Breast Cancer – A Literature Review Ismylatifa Devi; Diah Purwaningsari; Nita Pranitasari; HerinSetianingsih
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 3 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i3.15803

Abstract

Breast cancer was one of the most common types of cancer in women and the major cause of death. Chemotherapy in breast cancer caused toxicity to the normal cells, resistance to the drugs, and several other side effects. Seaweed had many functional compounds that could be used as adjuvant therapy in breast cancer because of its anti-cancer properties called the proapoptotic agent. These compounds were fucoidan, phloroglucinol, and fucoxanthin. Their proapoptotic mechanisms shown by the journal were through increasing proapoptotic protein expression, decreasing antiapoptotic protein expression, inducing oxidative stress production on the cancer cell, and inhibiting the PI3K pathway. This review concludes that the brown seaweed (Sargassum sp.), which contains fucoidan, phloroglucinol, and fucoxanthin, could increase breast cancer cells’ apoptotic process.
Reducing Natrium Chloride Concentration by Using the Alkali from Banana Stems in Bracket Water Inayah; Wahyuni Sahani; Syamsuddin S; Agus Erwin Ashari
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 3 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i3.15804

Abstract

Objective: This study aims to reduce the concentration of sodium chloride using banana stem media with a thickness of 10 cm, 15 cm, and 20 cm. Method: This type of research is quasi-experimental research by conducting trials of hard water management using banana stem media with variations in the thickness of the media, namely 10 cm, 15 cm, and 20 cm by replicating 3 times. Sampling was carried out in rivers containing chloride levels in Makassar. The sampling method is using Grab Sample which is taken directly from a river flow which is classified as brackish water. The data analysis technique was carried out by using the ANOVA test. Result: The results obtained are banana stem media with a thickness of 10 cm can reduce levels of chloride (Cl) 2377, 69 mg/l, a thickness of 15 cm can reduce levels of chloride (Cl) 1772.27 mg/l, and a thickness of 20 cm can reduce levels of chloride (Cl) 1166.18 mg/l. Conclusion: The decrease in chloride levels in water is due to the presence of 4.60 grams of charcoal hydrate content in banana stems which functions to bind chloride levels in the water, besides that there is also a membrane in the banana stem in the form of cellulose which plays a role in binding chloride levels in water and also as an osmosing. Banana stalks can bind chloride levels.
Detrimental Effect of Alprazolam on Sperm Viability ofMice (Mus musculus) Exposed to Chronic Unpredictable Mild Stress Intan Indah Permatasari; Reny I’tishom; HanikBadriyah Hidayati; Irwanto
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 3 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i3.15805

Abstract

Objective: This study aims to investigate the effect of alprazolam administration on sperm viability of mice (Mus musculus) strain Balb/C following CUMSfor 53 days. Method: This study used a true experimental design through randomization. Control group kept undisturbed without treatment and therapy throughout 60 days. K1 and K2 were exposed to a 53 day period of CUMS along with 7-day pretreatment adaptation. K2 was adapted for a week, stressed for 53 days along with cotreatment of alprazolam (4 mg/kg BW). Results: K1 and K2 showed insignificant improvement of sperm viability (p > 0.05).Meanwhile, K0 and K1 showed significant value compared to K2 (p<0.05). K2 showed little increase of sperm viability in CUMS group along with subsequent treatment of alprazolam. Conclusion: Overall, the results indicate an insignificant effect of alprazolam on sperm viability of CUMS-induced mice.
Mixed Methods Analysis: Traditional Medication,Stigma, and Leper’s Family Support Roles in Level II Leprosy Disability Irwan Saputra; T.M. Rafsanjani; Said Usman
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 3 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i3.15806

Abstract

People with a level II leprosy disability have limited functions in society. In Nagan Raya District, there is a 41% leprosy endemic area with a 5% level II disability rate. The goal of this research was to prove the relationships of traditional medication, stigma, and leper’s family support to level II leprosy disability. This research used mixedmethodsand a case-control design with 84 respondents42 case respondents (level II leprosy disability) and 42 control respondents (level 0 leprosy disability)chosen by consecutive sampling under some inclusion and exclusion criteria. Data collection used the in-depth interview method. This study used bivariate data analysis with the chi-square test and multivariate data analysis with the logistic regression test and the Miles and Huberman’s model. The results of the chi-square analysis indicated that traditional medication had p value=0.014 (OR: 2.3; 95% CI: 0.2–7.7), stigma p=0.04 (OR:3.6;95% CI: 1.5–8.9), and family’s support p=0.192 (OR:2.0; 95% CI: 0.7–5.8). The results of the logistic regression analysis showed that stigma was a risk factor for leprosy level II disability with p value=0.006, (OR=4.9; 95% CI: 1.6–15.1) and probability of 99.96%. Based on the interview results, lepers were feeling uncomfortable with the society’s not acceptingthem in a good way. This was especially the case with khanduri(feast) when it came down to food in that the society assumed lepers would transmit the infectious, disgusting disease. The Nagan Raya District Health Office is expected to encourage the societyto accept lepers and provide information regarding the process of leprosy transmission so as to appease the community’s fearand to prevent further disability.
Effectiveness of A Nutritional Instructional Program on Health-Related Outcomes for Hemodialysis Patients Ibrahem A. Al-Ashour; Widad K Mohammed
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 3 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i3.15809

Abstract

Objective: the study aimed to evaluate the effectiveness of a nutritional instructional program on healthrelated outcomes for hemodialysis patients through utilization of quality of life, and subjective global assessment in pretest; posttest1, posttest 2 and posttest 3.Methodology: quasi-experimental design was conducted at Al-Najaf Al–Ashraf, Specialized Center for Kidney Diseases and Transplantation. The study has been carried out during the period 1st September 2019 to 20th May 2020. The dietary instructions program constructed by researcher to measure the purpose of the study. The study sample of (76) patients referred for dialysis to the Specialized Center for Kidney Diseases and Transplantation. During the period of the study patients were selected through non-probability (purposively) and were randomly divided into two groups of (40) patients for study group and (36) patients for control group. The study group have been exposed to dietary instructional program by the researcher. The group that has not been exposed to dietary instructional program by the researcher are considered the control group. The measurement of effectiveness of dietary instructional program on patients undergoing hemodialysis through used of Quality-of-Life form and consisted of (5) main items. The subjective global assessment checklist questions and consisted of (6) items. Data was analyzed by using of descriptive data analysis (frequencies, percentages, mean, standard deviation, and graphical presentation) and by using of inferential analysis (chi-square, independent t-test, paired t-test, ANOVA test, and binominal test). Results: The results of the study demonstrated that there was non-significant difference between the study and control groups for quality-of-life score in pre dietary instructional program while; there was highly significant difference between the study and control groups for quality-of-life score in post dietary instructional program. The present study illustrated that there was non-significant difference between study and control groups in pretest at p-value (0.05), while there was highly significant difference in posttest (1,2, and 3) between study and control groups at p-value (0.05) regarding SGA.Conclusions: The study concluded that implementation instructional session will demonstrating a positive change in nutritional status and dietary habits. Difference between the two groups is due to the effectiveness of the dietary instruction program that given to the patients in the study group and not given to the control group. Recommendation: The study recommended that establishing of educational center for the patients in the hospital provided by adequate related materials, medias, audio-visuals aids and booklet for educating all patients how to cope with their medical conditions, when giving information to patients and relatives, nurses have more choices to make information clear and easily understandable

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