cover
Article Per Year (5 Year)
All
Home Page
OAI Link
Editorial Team
Contact
Reviewer
Google Scholar
Contact Name
Masriadi
Contact Email
arimasriadi@gmail.com
Phone
-
Journal Mail Official
-
Editorial Address
-
Location
Unknown,
Unknown
INDONESIA
Indian Journal of Forensic Medicine & Toxicology
Published by Official Organ of Indian Association of Medico-Legal Expert
ISSN : -     EISSN : -     DOI : -
Core Subject : Health,
Public Health
Arjuna Subject : Kedokteran - Epidemilogi
Articles 5,497 Documents
 51   52   53   54   55 
Correlation of CD4 and Distal Sensory Polyneuropathy in HivAids Patients Desti Ariani Kistanti1, Paulus Sugianto1, Erwin Astha Triyono2
Indian Journal of Forensic Medicine & Toxicology Vol. 14 No. 2 (2020): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v14i2.3134

Abstract

Infection of human immunodeficiency virus (HIV) and acquired immunodeficiency syndrome (AIDS) has developed into one of the most important health problems in the world. Distal sensory polyneuropathy (DSP) is the most common complication of peripheral neuropathy in HIV-AIDS. Risk factors associated with DSP are elderly, stage of HIV disease, (cluster differential-4) CD4 count, and high plasma viral load in plasma. To analyze the relationship between CD4 and distal sensory polyneuropathy in HIV-AIDS patients. Subjects of the study examined the degree of severity of distal sensory polyneuropathy by examination of the Surface Nerve Surgical Nerve Speed, then divided into case group and control group. After that, the subjects performed a CD4 count examination. Data analysis using chi-square test. Most body mass index (BMI) subjects did not experience malnutrition by 35% of case group and 35% control group (p = 1.000). Most subjects aged ?40 years were 37.5% of case group and 25% control group (p = 0.102). Analysis of CD4 relation with Speed of Nerve Surgical Nerve Survival was obtained p = 0.038. There was a significant relationship between CD4 and Distal Sensory Polyneuropathy in HIV-AIDS patients. While age and malnutrition were not found a significant relationship with distal sensory polyneuropathy.
Legal Efforts on Forensic Examination of the Death of Polling Station Working Committees (KPPS) Members Dewi Iriani1, Abdul Kadir1, Agus I Supriyanto1, Ahmad Arifin1, Made Wira Suhendra1
Indian Journal of Forensic Medicine & Toxicology Vol. 14 No. 2 (2020): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v14i2.3135

Abstract

Indonesia has held its general election on April 17th, 2019. During the 2019 general election, there were 11.239 members of polling station KPPS members passing out and 527 people passing away. Due to this circumstance, forensic examination is required to examine the reason behind the cases of the dead and the sick members. Therefore, this present article analyzes two issues: 1) how legal effort is conducted regarding health services provided for polling station KPPSmembers; and 2) what action the government do to take the responsibility on the death of the members. This research is categorized as legal research that employs four approaches. The first approach is statuary approach by using ordinatie sth No. 350 of 1957 Visum Et Repertum, preamble of 1945 State Constitution of Republic Indonesia article 179 of Criminal Code, Law of Health No. 36 of 2009 and Election Law No. 7 of 2017. The second one is case approach. The next is conceptual approach for both death and ill health cases. The last one is using comparative approach. The result showed that the members of polling station committee died due to some illness suffered by the members such as cardiovascular, heart attack, stroke, or even all of them. However, for members who do not suffer from hereditary disease, the cause the death is due to the heavy workload they had that surpasses 20 until 22 hours a day. Besides, lack of sleep is also considered contribute to the members’ death and sickness.
The Burden of Toxoplasma Gondii In Spontaneous Miscarriage and its Association with Rhoptry Protein 5 Gene and Toxoplasma gondii specific primers GRA 6 Gene Expression in Iraq Women Dhamyaa Kareem Kadhim1, Abdulsada Abdulabbas Rahi1
Indian Journal of Forensic Medicine & Toxicology Vol. 14 No. 2 (2020): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v14i2.3136

Abstract

Background: One of the major infectious micro-organism that is associated with spontaneous abortion is toxoplasmosis. Under diagnosis of toxoplasmosis and lack of understanding the exact mechanism and pathogenesis of spontaneous abortion associating toxoplasmosis are in our opinion the main problem facing clinicians who are concerned with categorization and management of spontaneous abortion in our pregnant ladies. Aim of the current study: to diagnose placental tissues parasitic infections using sophisticated nested PCR method in addition to evaluating gene expression of two pathogenetically Toxoplasma genes, namely ROP-5 and GRA-6, as a step toward estimating the exact prevalence of Toxoplasma associated spontaneous abortion in Iraqi community Patients and methods: The case control study was based on the inclusion of 101 women with spontaneous abortion and 20 pregnant ladies who succeeded to get pregnant serving as control group. The placental tissues were obtained from the pool of women visiting Al-Kut maternity teaching hospital for purpose of delivery or because of abortion. Those tissues were then processed in central laboratory using conventional PCR technique searching for evidence of toxoplasma gondii DNA. Obtained tissues were also subjected to real time PCR for detection of Rhoptry protein 5 gene expression and Toxoplasma gondii specific primers GRA 6. The lab work was done according to instruction of providing company. Results: Positive results were limited to women with spontaneous abortion, that is, none of control women had PCR evidence of Toxoplasma DNA in their placental tissues, 72 (71.3 %) versus 0 (0.0 %); the difference was highly significant (P < 0.001). An estimation of the risk of abortion accompanying toxoplasmosis has been carried out in terms of approximate Odds ratio and the results has been strikingly high (100.8). Both Rhoptry protein 5 and Toxoplasma gondii specific primers GRA 6 gene expressions have been significantly correlated to serum IgG and IgM positive tests in a negative way. Conclusion: PCR carried out on placental tissue is significantly higher sensitive in detecting toxoplasma gondii than serology and Both Rhoptry protein 5 and Toxoplasma gondii specific primers GRA 6 gene expressions play significant role in spontaneous abortion.
Changes of Interleukin-6 (IL-6) and Immunoglobulin G (igG) in Respiratory Excercise Didik Agus Santoso1, FM. judajana1, Elyana Asnar2
Indian Journal of Forensic Medicine & Toxicology Vol. 14 No. 2 (2020): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v14i2.3137

Abstract

Background: Skeletal muscle contraction in exercise will synthesize and release Interleukin-6 (IL-6) into the systemic circulation. IL-6 is a pleiotropic, proinflammatory and anti-inflammatory cytokine. IL-6 in exercise can modulate the immune response and metabolism in the liver, adipose tissue, Hypothalamushypophyse-adrenal (HPA). Objectives: To analyze and prove changes in levels of Interleukin-6 (IL-6) and Immunoglobulin G (IgG) in respiratory art sports of a exercise club. Methods: Thirty-four members of the breathing arts sport who met the inclusion criteria, male sex, adult age (?21 years), willing to participate were enrolled in this study. Examination of IL-6 and igG levels were performed by using Elisa method. The kit for IL-6 used Human IL-6 Immunoassay and IgG level used Total Human IgG Assay Results: The t-test results obtained p = 0.027 (p <0.05), there was a change between IL-6 pre-test and IL-6 post-test of breathing exercise for three weeks. The t-test results obtained p = 0.000 (p <0.05) there was a change between IgG level of pre-test and IgG post-test of breathing arts sports treatment, this change increased significantly. Conclusion: There was a change in levels of IL-6 and IgG in the breathing excercise.
Association between Stretching Exercise with Virtual Reality Game and Over Head Pulley of Frozen Shoulder Patients Donny Gunawan1, Reni Hendrarati Kusharyaningsih1, Noor Idha Handajani1
Indian Journal of Forensic Medicine & Toxicology Vol. 14 No. 2 (2020): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v14i2.3138

Abstract

Background and Objective: Frozen Shoulder (FS) or adhesive capsulitis is the most common musculoskeletal condition that causes pain and extensive restriction of joint motion. Virtual Reality (VR) provides a new option that is expected to help the rehabilitation program. The objective of the study was to compare the effect of stretching exercises with virtual reality games (VRG) and Over Head Pulley (OHP) through shoulder joint motion range (JMR) improvement and functional ability of FS. Method: This research was conducted on July to September 2012, in Medical Rehabilitation Outpatient Unit of Dr. Soetomo General Hospital Surabaya. The samples were frozen shoulder patients. These inclusion criteria were new or old unilateral FS patients, the limitations of shoulder JMR both passive and active, with a minimum limit of 30 ° compared to normal shoulder JMR at least 2 shoulder movements, flexion and abduction between 6 weeks to 6 months, aged 35-65 years. Result: The One-Sample Kolmogorov-Smirnov Test on the age range obained no significant differences (p = 0.418), the chi-square test on the sexes showed no significant differences (p = 1,000). The median of pleasure after treatment with the Mann-Whitney Test showed a non-significant difference (p = 0.317). Conclusion: Stretching exercises compared with VGR exercises in FS patients provided the same benefits of stretching with the OHP on improvement.
Correlation of Serum Alkaline Phosphatase, Lactate Dehydrogenase, C-Reactive Protein, Blood Deposition Rate, ?-Hcg Expression and Tumor Volume to Lung Metastasis Risk in Osteosarcoma Patients Achmad Fachrizal1, Dwikora Novembri Utomo1
Indian Journal of Forensic Medicine & Toxicology Vol. 14 No. 2 (2020): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v14i2.3139

Abstract

Osteosarcoma is the most common type of sarcoma that found in bone. The survival rate in osteosarcoma patients was less than 20.00% at the end of 1980 but is currently increasing to over 70.00% for nonmetastatic patients. The objective to analyze the correlation between Lactate Dehydrogenase (LDH), Alkaline Phosphatase (ALP), C-Reactive Protein (CRP), Blood Deposition Rate (LED) , hCG expression and tumor volume with pulmonary metastases in osteosarcoma patients. The subjects were osteosarcoma patients that the data taken from January 2015 to December 2016. The subjects will be clinical, radiological (plain, CT scan thorax, MRI) examinations, serum marker tests consisting of ALP, LDH, CRP and LED and histopathologic staining IHC ?-hCG. The study design was cross-sectional, while the statistical analysis used was normality test, Spearman correlation, chi-square test and logistic regression. The results majority of subjects were male (52.00%) and aged 11-20 years (85.00%). The tumor volume (p = 0.07), LDH levels (p = 0.07), and ALP levels (p = 0.016) were statistically significant for pulmonary metastases with moderate correlation (r = 0.587; 0.587; 0.53). The tumor volume was the most sensitive biomarker to diagnose lung metastasis in osteosarcoma patients (p = 0.171). Conclusion among other protein biomarkers, tumor volume was most sensitive in diagnosing pulmonary metastases. The volume of the tumor will increase the risk of pulmonary metastases in osteosarcoma patients.
Effect of Amniotic Membrane-Derived Mesenchymal Stem Cells on TNF-? Expression and Inflammatory Cells Infiltration during Vesicovaginal Fistule Repair Healing Process Eighty Mardiyan Kurniawati1, Agung Nur Rachman W1, Budi Santoso1, Harry Parathon1, Widjiati2, Fedik
Indian Journal of Forensic Medicine & Toxicology Vol. 14 No. 2 (2020): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v14i2.3140

Abstract

Background: Vesicovaginal fistula (VVF) causes high morbidity in women, affecting both physical and psychological condition. Until now, surgery is the mainstay treatment for this condition. However, prolonged exposure during inflammatory phase after surgery is still a problem in the healing process. TNF-? as potent pro-inflammatory cytokine plays an important role by attracting inflammatory cells to wound tissue. Amniotic membrane is the source for mesenchymal stem cells that had anti-inflammatory and imunomodulatory effect. This study aims to evaluate the effect of Amniotic Membrane-Derived Mesenchymal Stem Cells (AMMSC) on TNF-? expression and inflammatory cell infiltration during VVF repair healing process in New Zealand White (NZW) rabbit model. Method: This study was an experimental study with randomized posttest only control group design. Twentyseven NZW rabbit as VVF model was used in this study, randomly divided into 3 different treatment groups after underwent surgical treatment (no treatment <C group>, treated with freeze-dried amniotic membrane <T1 group>, and treated with freeze-dried amniotic membrane that seeded with AMMSC <T2 group>). Evaluation was done 7 days after treatment. TNF-? expression was evaluated semiquantitatively using modified Remmele-Stegner scale. Inflammatory cell infiltration was evaluated using modified Klopfleisch method. Results: Mean TNF-? expression between C, T1, and T2 group were significantly different (8.5 ± 1.6; 7.1 ± 1.2; 1.6 ± 1.2 respectively, p < 0.001). Median inflammatory cell infiltration between C, T1, and T2 group were significantly different (3.0; 2.0; 1.0 respectively, p < 0.001). Conclusion: AMMSC significantly reduced TNF-? expression and inflammatory cells infiltration during VVF repair healing process.
suPAR is a Bad Omen for Chronic Kidney Disease Progression Ekhlas Abdallah Hassan1, Fayhaa M. Khaleel2
Indian Journal of Forensic Medicine & Toxicology Vol. 14 No. 2 (2020): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v14i2.3141

Abstract

The rationale for considering serum soluble- urokinase plasminogen activator receptor (s-uPAR) concentration as a potential biomarker for incipient CKD was primarily based on reports that increased levels of this receptor will serve as a circulating permeability variable that may be impaired at the start of FSGS and DN, a crucial explanation for CKD. So in early stages(1-3) of CKD, suPAR was evaluated. The aims of present paper are to investigate whether patients with CKD have distinct circulating suPAR, that could lead to a potential development of noninvasive diagnostic biomarkers of the disease. And finally using healthy subjects as a control group to determine specificity and sensitivity . 135 subjects were incorporated in this study, 30 were healthy control, with mean age 48.7±9.7years, and they were 14 males and 16 females. 105CKD patient , with mean age 50.1±10.0years, they were 54 males and 51 females. Blood samples were collected. Serum after centrifugation was isolated for estimation of suPAR by Enzyme linked immune sorbent assay , creatinine, and urea by enzymatic method . Early morning urine sample was collected to be used for determination albumin creatinine ratio in patient . suPAR level was higher in CKD patients than in healthy control, 6.179±2.221 versus 2.303±0.475, respectively; the difference was highly significant (P < 0.001) .To study the potential role of suPAR in diagnosis of patients with CKD, ROC showed that the cutoff value of suPAR was > 3.5 ng / ml fold shift with sensitivity and specificity; the AUC was 0.826 (95 % confidence interval: 0.690-0.920) and therefore 82.6 % precision and significance level of (P < 0.001). In conclusion, The suPAR is significantly more effective and also more comprehensive to CKD clinical assessment and can be supported with creatinine blood analysis.
Interventions on Women Under Intimate Partner Violence: An Integrative Review Elaheh Asadi-Bidmeshki1, Jamileh Mohtashami2, Foroozan Atashzadeh-Shoorideh2, Meimanat Hosseini3
Indian Journal of Forensic Medicine & Toxicology Vol. 14 No. 2 (2020): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v14i2.3142

Abstract

The present study is aimed to determine the interventions on women under intimate partner violence. This integrative review was performed by searching in international (Web of science, PubMed, Scopus Science direct, and EMBASE) and national (SID and magiran) databases were searched from inception to December 31, 2018. The keywords used included “interventions” OR “IPV” OR “intimate partner violence”. The search of studies, data extraction and screening conducted by two researcher. Of 2782 studies 30 studies included in final stage. These studies were mainly investigated the effect of the intervention type on domestic violence against women. Of these, 17 studies focused on victims of domestic violence, of which 7 focused on supporting and empowering victims of violence, and 7 were interventional studies, and the remaining 3 studies were online and computer-based interventions. Another category of interventions focused on training and empowerment of health professionals and providers (7 studies), and two studies focused on both groups of DV victims and care providers. In addition to the DV victims and care providers, 4 studies included community factors in interventions. It also seems that carrying out comprehensive and adequate interventions on women under domestic violence is needed
The Effectiveness Comparison of Valproic Acid 500 mg and Amitriptyline 15 mg in Reducing the Frequency of Headache Attack in Patients with Tension-Type Headache Elsa Susanti1, Isti Suharjanti1
Indian Journal of Forensic Medicine & Toxicology Vol. 14 No. 2 (2020): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v14i2.3143

Abstract

Background: Tension-type headache (TTH) is the most common headache. Continuous analgesic use can develop into headache caused by drug abuse (medication overused headache); thus, the preventive therapy is necessary. Amitriptyline and valproic acid are drugs reported to reduce the frequency of headache in TTH patients. Objective: To analyze the effectiveness of valproic acid 500 mg and amitriptyline 15 mg in reducing the frequency of headache attack in patients with tension-type headache. Methods: The study applied a Double Blind Randomized Clinical Trial involving 50 TTH patients. The subjects were divided into two groups: amitriptyline 15 mg and valproate acid 500 mg. The period of drug administration was 6 weeks. The variables that were compared were the decreasing frequency of headache and the intensity of the pain. Results: There was no significant difference in the decrease of headache frequency (p = 0.730) and pain intensity (p = 0.430) between the amitriptyline group and valproate acid group. However, each drug effectively decreased the frequency of headache and pain intensity in TTH patients (p = 0.000). Conclusion: There was no significant difference between the effectiveness of valproic acid 500 mg and amitriptyline 15 mg in reducing the frequency of headache in patients with TTH.

Page 53 of 550 | Total Record : 5497

 51   52   53   54   55 

Filter by Year

2020 2022


Reset
Filter By Issues
All Issue Vol. 16 No. 3 (2022): Indian Journal of Forensic Medicine and Toxicology Vol. 16 No. 2 (2022): Indian Journal of Forensic Medicine & Toxicology Vol. 16 No. 1 (2022): Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 4 (2021): Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 3 (2021): Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 2 (2021): Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 1 (2021): Indian Journal of Forensic Medicine & Toxicology Vol. 14 No. 4 (2020): Indian Journal of Forensic Medicine & Toxicology Vol. 14 No. 3 (2020): Indian Journal of Forensic Medicine & Toxicology Vol. 14 No. 2 (2020): Indian Journal of Forensic Medicine & Toxicology Vol. 14 No. 1 (2020): Indian Journal of Forensic Medicine & Toxicology More Issue