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INDONESIA
Indian Journal of Forensic Medicine & Toxicology
Published by Official Organ of Indian Association of Medico-Legal Expert
ISSN : -     EISSN : -     DOI : -
Core Subject : Health,
Public Health
Arjuna Subject : Kedokteran - Epidemilogi
Articles 5,497 Documents
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Decrease of Epstein-Barr Virus Anti Early Antigen Imunoglobulin a Levels and Primary Tumor Size in PostCisplatin-Paclitaxel Chemotherapy in Nasopharyngeal Carcinoma Patients Elvi Syahrina Fiorisa1, Achmad Chusnu Rhomdhoni1, Budi Sutikno1, Anggraini Dwi Sensusiati1
Indian Journal of Forensic Medicine & Toxicology Vol. 14 No. 2 (2020): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v14i2.3144

Abstract

Background: Nasopharyngeal carcinoma (NPC) associated with Epstein-Barr virus (EBV) chronic infection is a common head and neck malignancy in South China and Indonesia. Although radiation and chemotheraphy is the main theraphy, it requires repeated and invasive biopsy for pathological evaluation. Therefore, a marker is required for screening including the level of anti early antigen imunoglobin a serology level. Method: Pre-pots test, longitudinal cohort design. The PTV of 18 samples were examined using CT scan, while their serum EBV anti EA IgA level were examined using pre and post three series-cisplatin-paclitaxel chemotherapy ELISA. Results: Although there was no significant changes in the level of anti EA IgA, however we found a decrease in the mean of pre-chemotherapy anti EA IgA level from 136.49 U/ml to 124.61 U/ml. There was significant changes in the VTP in pre and post-chemotherapy (p<0.05). The mean of VTP in pre-chemotherapy was 66.26 cm3 (SD-38.61 cm3), while in post-chemotherapy was 31.64 cm3 (SD-27.5 cm3). The delta mean of changes in anti EA IgA level was 11.8 U/ml and in VTP was 34.62 cm3. No correlation was found between the changes of anti EA IgA and the changes of VTP in post-chemotheraphy (p>0.05). However, decreases were found in the level of EBV EA IgA and PTV in pre and post NPC patients. Conclusion: There were decreases of serum EBV EA IgA level and PTV in pre and post-chemotherapy NPC patients.
Correlation of Cardiorespiratory Fitness Levels with Functional Mobility Abilitiy in Post Thrombotic Infarction Stroke Patient Eny Susilowati1, Reni Hendrarati Kusharyaningsih2, Dewi Poerwandari2
Indian Journal of Forensic Medicine & Toxicology Vol. 14 No. 2 (2020): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v14i2.3145

Abstract

Background: Stroke patients often experience functional ambulation difficulties and lack ability to walk independently due to the reduction cardiorespiratory fitness so that an understanding of the relationship between fitness levels cardiorespiratory with functional mobility ability is needed, especially for thrombotic infarction stroke patients.. Objectives: This study aims to assess the relationship between cardiorespiratory fitness levels with functional mobility ability in the first three months after thrombotic infarction stroke. Method: Subjects are 38 post trombotic infarction stroke. Functional mobility is measured by the Timed Up and Go test. Subjects were asked to stand up from a chair whose seat is ± 46cm and the height of its back is 65cm, walk as far as 3 m, turn 1800, walk back and sit back. Data were analyzed and performed statistical test using SPSS 17. Results: The study showed the average TUG test was 15.56-7.79 seconds with the longest travel time was 37.38 seconds and the fastest travel time was 8.16 seconds. The average of VO2max was 10.62 ± 2.31mL / kg / min, with the lowest VO2max yield of 5.78mL / kg / min and the highest was 14.54mL / kg / minute. The TUG test had a negative correlation with VO2max the 6 minute walk test result. Conclusion: There is a significant relationship between cardiorespiratory fitness level and functional mobility abilities in post thrombotic infarction stroke patient
The Early Detection in Gestational Diabetes Mellitus at Indonesia Primary Health Care Erni Rosita Dewi1, Budi Prasetyo2, Muhammad Ardian Cahya Laksana2, Hermanto Tri Joewono2, Ivon Diah
Indian Journal of Forensic Medicine & Toxicology Vol. 14 No. 2 (2020): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v14i2.3146

Abstract

Background: Gestational diabetes mellitus (GDM) is diabetes that is first diagnosed during pregnancy. Uncontrolled GDM or late found can increase mortality for both mother and baby. Not only bad medical conditions, but also it can decline the community productivity, affect socio-economic and increasing financial health. Early detection of GDM is crucial to be implemented by providers, especially in the primary health care. Objective: to determine the framework of early detection in gestational diabetes mellitus at primary health care Methods: The method used is a literature review, which was published in 2008-2018. The literature were collected using some keywords such as “detection”, “gestational diabetes mellitus”, and “primary health care” using PubMed and another electronic journal website. Furthermore, the findings were filtered based on our inclusion criteria and analyzed qualitatively. Results: Early detection of GDM in primary health care with risk factor assessment (age of pregnant women ? 35 years, some of bad history namely GDM in previous pregnancies, anti-diabetic drug use, diabetes mellitus in the family, congenital of infants, IUFD, preeclampsia, macrosomia, blood pressure examination, calculation of body mass index and random blood sugar examination). Furthermore, early detection of GDM is carried out by examining blood glucose accompanied by the provision of appropriate glucose solution interventions (OGCT and OGTT). Conclusion: primary health care can take more action in early detection of GDM through quality antenatal care, which can be done by applying the framework of early detection in gestational diabetes mellitus.
Observation of Oral Contrast Media Filling Into Lumen Appendix Faradilla litiloly1, Hartono Yudi Sarastika1
Indian Journal of Forensic Medicine & Toxicology Vol. 14 No. 2 (2020): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v14i2.3147

Abstract

Background: CT scan has become the imaging modality of choice in diagnosing appendicitis in unusual cases, replacing appendicogram with very little reliability. However, there is still an appendicogram demand in particular hospital in Indonesia. Objectives: This study aimed to obtain information on lumen appendix filling pattern with multi slice Multislice computed tomography (MSCT) scan using oral contrast media in patients without clinical appendicitis. Thus, it is able to provide additional information in the appendicogram interpretation. Method: This study was descriptive observational to 30 subjects selected by consecutive from April to June 2012. Subjects who underwent an abdominal MSCT scan using oral contrast media were analyzed descriptively by sex, age and lumen appendix filling pattern. Results: 30% of patients were men and women by 70%. The most common age group is 51-60 years (50%). Appendix of non-filling of 56.6%, partial filling of 43.3%, and no full filling appendix was obtained. Conclusion: Appendix filling as an indicator of the presence of appendicitis was not reliable in an abdominal MSCT scan using oral water soluble contrast, thus it needs to be considered when interpreting the appendicogram results
Study the Biological Efficiency of an Isolated Terpenic Compound from the Ether Petroleum Extract and the Trace Elements of the PlantTribulusterrestris Fatima S.Sabah Eman A.Mukhaifi
Indian Journal of Forensic Medicine & Toxicology Vol. 14 No. 2 (2020): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v14i2.3148

Abstract

Many different compounds with a spread of biological properties and chemical structures are known from genus Tribulusterrestris together with steroid and terpinoid. In gift study we tend to indicate the preliminary phytochemical analysis for rock oil ether extract and isolated compound. The results unconcealed that there was no alkaloids, supermolecule , glycosides, saponins and tannic acid inpetroleum ether however contain ,steroid and terpinoid. The isolated compound contained solely terpinoid compound. attention procedure was last this compounds. the FTIR qualitative analysis knowledge of isolated compound showed discovered absorptions signal . ultraviolet illumination spectrum showed most absorption at 220 nm due to???*transition that is taken into account as characteristic feature of the unsaturated covalent bond. The concentration of the weather analyzed during this study decrease within the order Fe>Ca>Cu>Zn>Cr. important totally different among microorganism toward T. terrestris oil with p<0.05 and LSD 15.4 ,highest MIC by E.coli about 50 mm in 100% concentration of T. terrestrisoil compared with control.
Medico-legal Significance of Diatoms Detection in Different Organs of Drowning Victims Haidar N. Hussein1, Nabeel G. Hashim2, Niran M. Ahmed3
Indian Journal of Forensic Medicine & Toxicology Vol. 14 No. 2 (2020): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v14i2.3149

Abstract

Background: Drowning is a main universal community health problem & In Medico- Legal Aspect the autopsy diagnosis of drowning presents one of the major problems especially when there is delay in recovering the victim from water.This study concentrates on the significance of diatoms detection in different organs to reach more accurate diagnosis of drowning. Objective: To determine the diagnostic features of drowning depending on detection of diatoms in deep tissues of drowning victims. Methods: This study was performed at Medico-legal Directorate (M.L.D.) in Baghdad for (12) months within the period from 1/1/2018- 31/12/2018. Full proper autopsy including external and internal examination of the body for all cases was performed, after obtaining complete medico-legal history, in addition to diatoms detection in different organs of drowning victims to determine the cause of the death as due to drowning. Results: The study included (60) cases, (52) male and (8 ) female with their ages ranged between ( 15-44 years old) for male , while ages ranged between (1-44 years old) for females . Drowning was the cause of death in all cases. Among the most important results of this study is the presence of diatoms in the different organs of the drowning cases. The diatoms were found in the lung in all drowning cases (100%), and found in other organs in a percentage that increased with the duration of immersion. Conclusion: Drowning is the 10th cause of violent deaths in Baghdad. And important point in the diagnosis of drowning by detection of diatoms in different organs of drowning cases and pennate diatoms was common type in Iraqi waters and also study showed Aulacasiera granulata sp. common in Iraq
Evaluation of Nurses’ Knowledge and Attitudes toward Pain Management at Baghdad Teaching Hospitals Haider M. Majeed1, Ahmed F.Hassan1, Raja I. Abid2
Indian Journal of Forensic Medicine & Toxicology Vol. 14 No. 2 (2020): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v14i2.3150

Abstract

Poorly managed or unmanaged pain is a problem that affects individuals, entire healthcare systems and societies throughout the world . Objectives: To assess nurses’ knowledge and attitudes about patient’s pain management and to find out the relationship between knowledge , attitudes and their demographical characteristic. Methodology: A descriptive cross sectional design study was carried out among 100 nurses working in male and female surgical wards, ICU, surgical ward, emergency and operating theatre of four teaching hospitals, Baghdad city. Census method was used to select the participants, in which all the nurses working in the selected wards who agreed to participate in the study were selected. Data was collected by distributing structured self-administered questionnaire which was a modified form of a standard tool, that is, Nurses’ Knowledge and Attitude Survey Regarding Pain (NKASRP) developed by Ferrel and McCaffery. Results: The majority of the study were male who accounted for (63%) of the total participants while female constituted (37%). Most of participants (49%) were ages between (18 – 27) years old, a high percentage of them were have institute graduate (40%), (50%) of the nurses were single and the remainder was married. Majority of them (37%) were employee (1-5) years in employment in nursing. Majority of them (45%) were employee (1-5) years in intensive care unit, and finally majority of nurses (77%) have training session about patient’s pain management. Conclusions: This study indicated that nurses’ have poor knowledge about pain management, as well as study indicated overall nurses’ have positive attitudes toward pain management.
The Effect of Empowerment Program on Participation of Mothers with Premature Infants Hospitalized in Neonatal Intensive Care Unit Hania Sajadi1, Golbahar Akhundzadeh2, Hamid Hojjati3
Indian Journal of Forensic Medicine & Toxicology Vol. 14 No. 2 (2020): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v14i2.3151

Abstract

Introduction: The birth of a premature infant who needs to be admitted to neonatal intensive care unit from birth impedes early communication and participation of mother in her infant’s care. The purpose of this study was to determine the effect of empowerment program on the participation of mothers with premature infants admitted to neonatal intensive care unit. Method: This study was a randomized clinical trial in 2018, which was conduct on a sample of mothers with premature infant who had randomly been divided into two intervention and control groups. The data collection tools were the Parents’ Participation Inventory designed by Melnick in 1994. Data were analyzed by descriptive statistics (tables, mean and standard deviation) and inferential statistics using SPSS-16 software. Results: There was no significant difference in the level of mothers’ participation in the care of their infants between the two groups before the intervention (p = 0.45). But after the empowerment training program, the results showed that mothers’ participation in the intervention group (19.10 ± 3.09) was higher than the control group (16.8 ± 2.01), (p = 0.01). Conclusion: The results of this study showed that implementation of empowerment training program increases mothers’ participation in the care of their premature infants. Early intervention and the use of written information along with the booklet will increase the mothers’ participation in the care of their infant.
Association of Diffusion Weighted Magnetic Resonance Imaging Profile and Apparent Diffusion Coefficient Value with Brain Tumor’s Histopathology Hartati Rusmi Tri Wilujeng1, Anggraini Dwi Sensusiati2, M. Yamin Sunaryo Suwandi3
Indian Journal of Forensic Medicine & Toxicology Vol. 14 No. 2 (2020): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v14i2.3152

Abstract

Background: Accuracy of preoperative brain tumor’s histopathologic differentiation is very important to determine preoperative staging, intraoperative management and postoperative therapy. Diffusion weighted magnetic resonance imaging is an advanced technique developed as an important method for brain tumor assessment. Objectives: This study aimed to investigate correlation between diffusion weighted imaging (DWI) profile and apparent diffusion coefficient (ADC) value with brain tumor’s histopathology. Methods: This study examined 86 subjects with brain tumors using magnetic resonance imaging and histopathology examination at Dr. Soetomo Teaching Hospital and evaluated DWI profile and ADC maps. The spherical ROI on ADC maps was placed on the solid part of the tumor to measure ADC value. Spearman’s correlation test was conducted to determine correlation between DWI profile and ADC values with histopathological grading and types of brain tumor. Results: There was a significant correlation between DWI profile and ADC values (p = 0.000), as well as DWI and ADC values with histopathological grading and types of brain tumor (p = 0.000). There was an inverse corelation between ADC value and histopathological grading. The higher the ADC value, the lower the brain tumor grade, while lower ADC value resulted in high tumor grade. The average ADC value of grade-1 meningiomas was 1.061±0.257 x 10-3 mm2/sec, pilocytic astrocytoma was 1.301±0.107 x 10-3 mm2/ sec, glioblastoma multiforme was 0.831±0.080 x 10-3 mm2/sec, and medulloblastomas was 0.600±0.078 x 10-3 mm2/sec. Conclusion: Evaluation on DWI profile and ADC value could provide additional information on conventional magnetic resonance imaging examination to determine histopathological grading and types of both intra and extra-axial brain tumors.
Mitochondrial 16S rRNA gene-dependent Blood typing as a Forensic Tool Hayder J.H. Al-Nayili1, Hussein O.M. Al-Dahmoshi2
Indian Journal of Forensic Medicine & Toxicology Vol. 14 No. 2 (2020): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v14i2.3153

Abstract

Background: Mitochondrial DNA is an important tool for human identification and is used to differentiate between human and animal blood at the crime scene, because in extreme conditions nuclear DNA is severely destroyed while Mitochondrial DNA contains multiple copies (200-2000) in per cell as well as resists harsh and more stable conditions. Methodology: Seventy-two blood samples were collected from human (Homo sapiens), sheep (Ovis aries), goat (Capra hircus) and cow (Bos taurus) (Eighteen blood samples for each). All blood samples were withdrawn by technician and 5ml were aspirated using aseptic technique and transferred to EDTA-Na2 tube and mixed well and stored in refrigerator. The collection takes 2 weeks (15th May 2019 to 30th May 2019). All samples were collected from Al-Diwanyia city. Results: The results of PCR reveal that, the primer pairs were specific and non-specific products not appear for all samples. The amplification of Homo sapiens mitochondrial DNA with primer pairs of other (Ovis aries, Capra hircus and Bos taurus) and amplification of each with primers pair of another genus gave negative results and this a primary evidence for primer pairs specificity. The amplicon of 16S rRNA gene of Homo sapiens were 1200bp ,Ovis aries were 1060bp ,Capra hircus were 820bp , and Bos taurus were 1300bp. The sequencing revealed that no crossreactivity of designed primer pairs and the PCR assay based on the designed primer pairs will be simple, fast, sensitive, specific, and cost-effective. Conclusion: Sensitivity, specificity and accuracy of the designed species specific primer pairs and applicability of the designed primer pairs in forensics to investigate blood sports or evidence belonging for human, sheep, goat and cow.

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